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公开(公告)号:US07241770B2
公开(公告)日:2007-07-10
申请号:US11007255
申请日:2004-12-09
申请人: Matthias Mentzel , Dania B. Reiche , Reinhard Brückner , Samuel David , Bartholomeus J. Van Steen , Uwe Schön , Daniel Jasserand , Ulf Preuschoff
发明人: Matthias Mentzel , Dania B. Reiche , Reinhard Brückner , Samuel David , Bartholomeus J. Van Steen , Uwe Schön , Daniel Jasserand , Ulf Preuschoff
IPC分类号: A61K31/438 , C07D471/10
CPC分类号: C07D471/10
摘要: The invention relates to a group of hydronopol derivatives which are agonists on human ORL1 (nociceptin) receptors. The invention also relates to the preparation of these compounds, to pharmaceutical compositions containing a pharmacologically active amount of at least one of these novel hydronopol derivatives as an active ingredient, as well as to the use of these pharmaceutical compositions for the treatment of disorders in which ORL1 receptors are involved.The invention relates to compounds of the general formula (1) wherein the symbols have the meanings as given in the description.
摘要翻译: 本发明涉及作为人类ORL1(伤害感受素)受体的激动剂的一组水诺酮衍生物。 本发明还涉及这些化合物的制备,含有药理学活性量的这些新型水葫芦醇衍生物中的至少一种作为活性成分的药物组合物,以及这些药物组合物用于治疗其中 涉及ORL1受体。 本发明涉及通式(1)的化合物,其中符号具有说明书中给出的含义。
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公开(公告)号:US06445276B2
公开(公告)日:2002-09-03
申请号:US09262475
申请日:1999-03-04
申请人: Uwe Schön , Dieter Bornhorst , Joachim Korherr , Joachim Jüngst
发明人: Uwe Schön , Dieter Bornhorst , Joachim Korherr , Joachim Jüngst
IPC分类号: H01H85055
CPC分类号: H01H85/46 , H01H85/36 , H01H2085/0266 , H01H2085/466 , Y10T307/865
摘要: A fuse apparatus (1) is provided for selectively interrupting a load current (Ia) flowing between a pair of associated conductor leads. The fuse apparatus includes at least two spaced apart electrically conductive contact elements (5) operatively connected with the associated conductor leads. A fuse element (7) is connected to the contact elements (5) using an electrically conductive connection material (9) to allow the current (Ia) to flow between the pair of associated conductor leads. The connection material (9) is adapted to electrically disconnect the fuse element (7) from the contact elements (5) when the current (Ia) exceeds a predetermined current intensity. The connection material (9) has an intrinsic electrical transition resistance characteristic whereby the material develops a temperature in proportion to an intensity of the current. The connection material melts as the current increases to separate the fuse element from the contact elements.
摘要翻译: 提供了一种熔丝装置(1),用于选择性地中断在一对相关联的导体引线之间流动的负载电流(Ia)。 保险丝装置包括与相关联的导体引线可操作地连接的至少两个间隔开的导电接触元件(5)。 使用导电连接材料(9)将熔丝元件(7)连接到接触元件(5),以允许电流(Ia)在所述一对相关联的导体引线之间流动。 当电流(Ia)超过预定电流强度时,连接材料(9)适于将熔丝元件(7)与接触元件(5)电断开。 连接材料(9)具有本征的电过渡电阻特性,由此该材料与电流的强度成比例地形成温度。 当电流增加时,连接材料熔化,以将熔丝元件与接触元件分开。
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公开(公告)号:US07634917B2
公开(公告)日:2009-12-22
申请号:US11576406
申请日:2005-09-30
申请人: Günter Fuhr , Heiko Zimmermann , Young-Joo Oh , Uwe Schön
发明人: Günter Fuhr , Heiko Zimmermann , Young-Joo Oh , Uwe Schön
IPC分类号: F25D25/00
CPC分类号: A01N1/02 , A01N1/0257 , F25D3/10 , F25D2600/06 , F25D2700/16 , G01N1/42
摘要: The invention relates to a cryoapparatus for freezing and/or thawing a sample (1), especially in the cryopreservation of a biological sample (1), with a coolable cooling space (3) and with a sample container (10) arranged in the cooling space (3) for temporarily receiving the sample (1) when freezing or thawing the sample (1). It is suggested that the sample container (10) can be tempered separately from the cooling space. Furthermore, the invention includes an associated operating method.
摘要翻译: 本发明涉及一种用于冷冻和/或解冻样品(1)的冷冻装置,特别是在具有可冷却冷却空间(3)的冷冻保存中的生物样品(1)的冷冻保存以及布置在冷却中的样品容器(10) 用于在冷冻或解冻样品(1)时临时接收样品(1)的空间(3)。 建议将样品容器(10)与冷却空间分开回火。 此外,本发明包括相关的操作方法。
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公开(公告)号:US07596957B2
公开(公告)日:2009-10-06
申请号:US10564904
申请日:2004-07-19
申请人: Günter Fuhr , Uwe Schön , Heiko Zimmermann , Young-Joo Oh
发明人: Günter Fuhr , Uwe Schön , Heiko Zimmermann , Young-Joo Oh
IPC分类号: F24F3/16
CPC分类号: G01N1/42 , A01N1/0252 , B25J21/02
摘要: The invention relates to a device and method for handling a probe, in particular, for treating, examining, inserting or extracting a cryoprobe. According to the invention, said probe is surrounded by an ambient gas, during handling, and an air-conditioning device (33) cools, dries and/or at least partially replaces the ambient gas by a protective gas, in order to prevent deterioration of the probe by the ambient gas during handling.
摘要翻译: 本发明涉及一种用于处理探头的装置和方法,特别是用于处理,检查,插入或提取冷冻探针。 根据本发明,在处理期间,所述探针被环境气体包围,并且空气调节装置(33)通过保护气体冷却,干燥和/或至少部分地替代环境气体,以防止劣化 在处理期间由环境气体探测。
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公开(公告)号:US06520019B1
公开(公告)日:2003-02-18
申请号:US09673550
申请日:2001-01-19
申请人: Uwe Schön , Cornelius Peter , Frank Hacke
发明人: Uwe Schön , Cornelius Peter , Frank Hacke
IPC分类号: G01H1108
CPC分类号: G01H11/08 , G01D11/30 , G10K11/004
摘要: The invention relates to an Ultrasound Sensor, especially for a vehicle and the passenger compartment thereof, comprising a can-shaped housing, a housing base, a housing closure and a sensor element arranged at the base inside the housing, and in the area of the housing closure there is arranged a contact device which is attachable, in locally fixed fashion, inside housing; the contact device presenting, in the direction of the longitudinal axis, a penetrating recess and being connected, in electrically conductive fashion, in at least one contact point with at least one electrode of the sensor element by means of thick-stranded wire. The invention also relates to a method for producing the Ultrasound Sensor.
摘要翻译: 本发明涉及一种超声波传感器,特别是一种用于车辆及其乘客舱的超声波传感器,包括壳体,壳体基座,壳体封闭件和布置在壳体内部的基座处的传感器元件,以及在 壳体封闭件布置有接触装置,其可以局部固定的方式附接到壳体内; 所述接触装置在所述纵向轴线方向呈现穿透凹槽,并且以导电的方式通过粗绞线与所述传感器元件的至少一个电极在至少一个接触点中连接。 本发明还涉及一种用于生产超声波传感器的方法。
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公开(公告)号:US20120177557A1
公开(公告)日:2012-07-12
申请号:US13383965
申请日:2010-05-17
申请人: Hartwig Rauleder , Ekkehard Müh , Reinhold Schork , Uwe Schön
发明人: Hartwig Rauleder , Ekkehard Müh , Reinhold Schork , Uwe Schön
IPC分类号: C01B33/107 , B01J37/08 , B01J31/06
CPC分类号: B01J31/08 , B01J37/08 , B01J41/04 , B01J41/07 , C01B33/107 , C01B33/10773 , C01P2006/80 , C07F7/125
摘要: The invention relates to a process for treating a substantially water-containing amino-functional, polymeric catalyst precursor while retaining the inner porous structure thereof and the outer spherical form thereof to form a catalyst, in which the catalyst precursor is treated at mild temperatures and under reduced pressure to prepare a catalyst having a water content below 2.5% by weight. The process is preferably integrated into an industrial scale process for preparing dichlorosilane, monosilane, silane, or solar silicon or semiconductor silicon from silanes.
摘要翻译: 本发明涉及一种用于处理基本上含水氨基官能的聚合催化剂前体的方法,同时保持其内部多孔结构和其外部球形形式,以形成催化剂,其中催化剂前体在温和的温度下和在 减压以制备水含量低于2.5重量%的催化剂。 该方法优选整合到从硅烷制备二氯硅烷,硅烷,硅烷或太阳硅或半导体硅的工业规模方法中。
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公开(公告)号:US20070267419A1
公开(公告)日:2007-11-22
申请号:US11576406
申请日:2005-09-30
申请人: Günter Fuhr , Heiko Zimmermann , Young-Joo Oh , Uwe Schön
发明人: Günter Fuhr , Heiko Zimmermann , Young-Joo Oh , Uwe Schön
IPC分类号: F25D3/10
CPC分类号: A01N1/02 , A01N1/0257 , F25D3/10 , F25D2600/06 , F25D2700/16 , G01N1/42
摘要: The invention relates to a cryoapparatus for freezing and/or thawing a sample (1), especially in the cryopreservation of a biological sample (1), with a coolable cooling space (3) and with a sample container (10) arranged in the cooling space (3) for temporarily receiving the sample (1) when freezing or thawing the sample (1). It is suggested that the sample container (10) can be tempered separately from the cooling space. Furthermore, the invention comprises an associated operating method.
摘要翻译: 本发明涉及一种用于冷冻和/或解冻样品(1)的冷冻装置,特别是在具有可冷却冷却空间(3)的冷冻保存中的生物样品(1)的冷冻保存以及布置在冷却中的样品容器(10) 用于在冷冻或解冻样品(1)时临时接收样品(1)的空间(3)。 建议将样品容器(10)与冷却空间分开回火。 此外,本发明包括相关的操作方法。
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