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    Monoterpenes, sesquiterpenes and diterpenes as cancer therapy
    5.
    发明授权
    Monoterpenes, sesquiterpenes and diterpenes as cancer therapy 失效
    单萜，倍半萜烯和二萜类作为癌症治疗

    公开(公告)号：US5602184A

    公开(公告)日：1997-02-11

    申请号：US25471

    申请日：1993-03-03

    申请人： Charles E. Myers ,  Jane Trepel ,  Edward Sausville ,  Dvorit Samid ,  Alexandra Miller ,  Gregory Curt

    发明人： Charles E. Myers ,  Jane Trepel ,  Edward Sausville ,  Dvorit Samid ,  Alexandra Miller ,  Gregory Curt

    IPC分类号： A61K31/01 ,  A61K31/015 ,  A61K31/045 ,  A61K41/00 ,  H61K31/045

    CPC分类号： A61K31/01 ,  A61K31/015 ,  A61K31/045 ,  A61K41/0038

    摘要： The invention provides methods of treating cancer including administering an effective amount of selected terpenes to a mammal having the cancer when the cancer is prostate cancer, colon cancer, astrocytoma, or sarcoma. The terpene is selected from the group consisting of a cyclic monoterpene, a noncyclic monoterpene, a noncyclic sesquiterpene and a noncyclic diterpene. The invention also provides a method of sensitizing a cancer to radiation including administering an effective amount of a terpene to a mammal having the cancer wherein the terpene is selected from the group noted above. Additionally, the invention provides methods of inhibiting the growth of cancer cells including applying an effective amount of a selected terpene to the cancer cells which are cells of prostate cancer, colon cancer, osteosarcoma, or glioblastoma.

    摘要翻译： 本发明提供了治疗癌症的方法，包括当癌症是前列腺癌，结肠癌，星形细胞瘤或肉瘤时向具有癌症的哺乳动物施用有效量的选择的萜烯。 萜烯选自环状单萜，非环状单萜，非环倍半萜烯和非环双萜。 本发明还提供了使癌症对辐射致敏的方法，包括向具有癌症的哺乳动物施用有效量的萜烯，其中萜烯选自上述组。 此外，本发明提供抑制癌细胞生长的方法，包括将有效量的选择的萜烯施用于作为前列腺癌，结肠癌，骨肉瘤或成胶质细胞瘤的细胞的癌细胞。

    Toner dispensing apparatus
    6.
    发明授权
    Toner dispensing apparatus 失效
    墨粉分配装置

    公开(公告)号：US3985098A

    公开(公告)日：1976-10-12

    申请号：US542319

    申请日：1975-01-20

    申请人： Charles E. Myers ,  James E. Genthe

    发明人： Charles E. Myers ,  James E. Genthe

    IPC分类号： G03G15/08

    CPC分类号： G03G15/0891 ,  G03G15/0877

    摘要： A toner dispensing apparatus for electrophotographic copiers. The dispenser includes an elongated hollow tubular member extending across the developer assembly of the copier within which is positioned a rotatable auger of novel construction having a helical groove formed around its surface. One end of the auger extends out of the tubular member into a toner supply container which is adapted to feed fresh toner into the groove of the auger. Rotation of the auger transports closely metered amounts of toner from the supply container into and along the tubular member and as it is carried there along, the toner will be automatically dispensed in precise amounts through a plurality of apertures extending along the bottom of the tubular member. According to one important feature of the invention, the toner dispenser is supported across the developer assembly in a position to dispense toner into the developer as it is falling from the development zone toward the elevator sump. This provides an opportunity for effective mixing of the toner with the developer without the need for rotating mixing screws or the like in the elevator sump, although a stationary crossmixer is preferably provided to assist in the mixing activity.

    摘要翻译： 一种用于电子照相复印机的调色剂分配装置。 分配器包括延伸穿过复印机的显影剂组件的细长的中空管状构件，其中定位有具有围绕其表面形成的螺旋槽的新颖结构的可旋转螺旋钻。 螺旋钻的一端从管状构件延伸到调色剂供应容器中，该调色剂供应容器适于将新鲜调色剂输送到螺旋推运器的凹槽中。 螺旋钻的旋转将来自供应容器的紧密计量的调色剂从管状构件输送并沿着管状构件运送，并且随着其被携带在那里，调色剂将通过沿着管状构件的底部延伸的多个孔以精确的量自动分配 。 根据本发明的一个重要特征，调色剂分配器被支撑在整个显影剂组件上，以便当调色剂从显影区向着电梯槽排出时将调色剂分配到显影剂中。 这提供了调色剂与显影剂的有效混合的机会，而不需要在电梯槽中旋转混合螺杆等，尽管优选地提供固定的交错混合器来辅助混合活动。