公开(公告)号：US20210262013A1

公开(公告)日：2021-08-26

申请号：US17180337

申请日：2021-02-19

Applicant: McMaster University

Inventor： Carlos Filipe ,  Yingfu Li ,  Sahar Esmaeili Samani ,  Dingran Chang ,  Erin M. McConnell ,  Meghan Rothenbroker

IPC: C12Q1/6823

Abstract: This disclosure relates to biosensors, and in particular, biosensors based on nucleic acid cleaving enzymes such as ribonucleotide-cleaving DNAzymes for the detection of analytes, and methods of use.

公开(公告)号：US20240352540A1

公开(公告)日：2024-10-24

申请号：US18642242

申请日：2024-04-22

Applicant: McMaster University

Inventor： Yingfu Li ,  Shuwen Qian ,  Dingran Chang ,  Jimmy Gu ,  Bruno Salena

IPC: C12Q1/689 ,  C12Q1/6818

CPC classification number: C12Q1/689 ,  C12Q1/6818

Abstract: This disclosure relates to catalytic nucleic acids, catalytic nucleic acid probes, biosensors, and kits for detecting the presence of Clostridium difficile. Also provided are methods for detecting the presence of Clostridium difficile in a test sample, using the catalytic nucleic acids, catalytic nucleic acid probes, biosensors, and kits.

公开(公告)号：US11692215B2

公开(公告)日：2023-07-04

申请号：US17180337

申请日：2021-02-19

Applicant: McMaster University

Inventor： Carlos Filipe ,  Yingfu Li ,  Sahar Esmaeili Samani ,  Dingran Chang ,  Erin M. McConnell ,  Meghan Rothenbroker

IPC: C12Q1/6825 ,  C12Q1/6823

CPC classification number: C12Q1/6823 ,  C12Q1/6825 ,  C12Q1/6825 ,  C12Q2521/301 ,  C12Q2521/327 ,  C12Q2521/337 ,  C12Q2521/345 ,  C12Q2527/127 ,  C12Q2563/107

Abstract: This disclosure relates to biosensors, and in particular, biosensors based on nucleic acid cleaving enzymes such as ribonucleotide-cleaving DNAzymes for the detection of analytes, and methods of use.