公开(公告)号：US12114964B2

公开(公告)日：2024-10-15

申请号：US16883387

申请日：2020-05-26

Applicant: TOHOKU UNIVERSITY

Inventor： Makoto Yoshizawa ,  Norihiro Sugita

IPC: A61B5/021 ,  A61B5/00 ,  A61B5/024 ,  A61B5/347 ,  A61B5/374

CPC classification number: A61B5/02116 ,  A61B5/02416 ,  A61B5/347 ,  A61B5/374 ,  A61B5/7257 ,  A61B5/7278 ,  A61B5/7435

Abstract: A biological information measuring apparatus includes a distortion calculating unit that calculates, based on video pulse wave information representing a video pulse wave expressing a temporal change in a brightness value included in a video signal of a predetermined part of a subject, a waveform distortion obtained from a heartbeat basic component containing a frequency component of a heartbeat frequency band corresponding to a heart rate of the subject and a heartbeat high-frequency component related to a waveform of a pulse wave and containing a frequency component of a frequency band higher than the heartbeat frequency band, the heartbeat basic component and the heartbeat high-frequency component being included in the video pulse wave; and a measuring unit that measures a fluctuation in a blood pressure of the subject based on the waveform distortion calculated by the distortion calculating unit.

公开(公告)号：US20240315635A1

公开(公告)日：2024-09-26

申请号：US18734876

申请日：2024-06-05

Applicant: Covidien LP

Inventor： Susanne Koch ,  Claudia Spies

IPC: A61B5/374 ,  A61B5/00 ,  G01R23/15 ,  G16H10/60 ,  G16H50/20 ,  G16H50/70

CPC classification number: A61B5/374 ,  A61B5/7271 ,  G16H10/60 ,  G16H50/70 ,  G01R23/15 ,  G16H50/20

Abstract: The present disclosure relates to methods and devices for providing parameters that indicate a higher likelihood of a postoperative delirium occurring. According to an aspect of the present disclosure, the following steps are provided: detecting at least one EEG signal at the head of the patient; determining the average amplitude of the “direct current” EEG signal; checking whether an increase in the determined average amplitude when entering anesthetic-induced loss of consciousness is above a predefined amount, and in the event of this, providing a corresponding information in the form of a parameter that shows a higher likelihood of a postoperative delirium occurring.

公开(公告)号：US20240315611A1

公开(公告)日：2024-09-26

申请号：US18593847

申请日：2024-03-01

Applicant: SynchNeuro, Inc.

Inventor： Casey HALPERN ,  Emily MIRRO ,  Cammie ROLLE ,  Emmanuel DUMONT

IPC: A61B5/145 ,  A61B5/00 ,  A61B5/374

CPC classification number: A61B5/14532 ,  A61B5/0006 ,  A61B5/374 ,  A61B5/6814

Abstract: Blood glucose states based at least on sensed brain activity data. Blood glucose states may be predicted states using prediction models, and may be real-time or future glucose states. One or more wearable sensors, optionally adapted for use in either single channel or dual channel sensing, can record brain activity signals and communicate brain activity signal data to a remote device.

公开(公告)号：US12097037B2

公开(公告)日：2024-09-24

申请号：US16624452

申请日：2018-06-20

Applicant: The Trustees of Columbia University in the City of New York ,  The Nathan S. Kline Institute for Psychiatric Research

Inventor： Daniel Javitt ,  Antigona Martinez ,  Yaakov Stern

IPC: A61B5/378 ,  A61B5/00 ,  A61B5/374

CPC classification number: A61B5/378 ,  A61B5/374 ,  A61B5/4088 ,  A61B5/7257

Abstract: An exemplary system, method, and computer-accessible medium for generating diagnostic data associated with a likelihood a patient(s) developing a mental disease(s) can be provided, which can include, for example, providing a visual patterns to the patient(s), receiving electroencephalogram (EEG) information from the patient(s) that can be based on the visual pattern(s); and generating the diagnostic data based on the EEG information.

公开(公告)号：US20240293048A1

公开(公告)日：2024-09-05

申请号：US18593845

申请日：2024-03-01

Applicant: SynchNeuro, Inc.

Inventor： Casey HALPERN ,  Emily MIRRO ,  Cammie ROLLE ,  Emmanuel DUMONT

IPC: A61B5/145 ,  A61B5/00 ,  A61B5/374

CPC classification number: A61B5/14532 ,  A61B5/374 ,  A61B5/6814 ,  A61B5/7264 ,  A61B5/742

Abstract: Blood glucose states based at least on sensed brain activity data. Blood glucose states may be predicted states using prediction models, and may be real-time or future glucose states. One or more wearable sensors, optionally adapted for use in either single channel or dual channel sensing, can record brain activity signals and communicate brain activity signal data to a remote device.

公开(公告)号：US12076152B2

公开(公告)日：2024-09-03

申请号：US16755768

申请日：2018-10-19

Applicant: LIFESCAPES Inc. ,  Keio University

Inventor： Junichi Ushiba ,  Koji Morikawa

IPC: A61B5/37 ,  A61B5/00 ,  A61B5/291 ,  A61B5/374 ,  G06F3/01

CPC classification number: A61B5/291 ,  A61B5/374 ,  A61B5/6803 ,  G06F3/015

Abstract: An electroencephalogram decision system determines, when finding electroencephalogram information representing an electroencephalogram obtained by an electrode unit placed on a region of interest that forms part of a subject's head satisfying a predetermined condition, that a target electroencephalogram, which is an electroencephalogram with a characteristic variation, should have been produced. The predetermined condition is selected from of detection conditions including a first type of condition and a second type of condition. The first type of condition specifies that a decision should be made, based on a component falling within a single frequency band included in the electroencephalogram represented by the electroencephalogram information, whether or not the target electroencephalogram has been produced. The second type of condition specifies that a decision should be made, based on components falling within multiple different frequency bands included in the electroencephalogram represented by the electroencephalogram information, whether or not the target electroencephalogram has been produced.

公开(公告)号：US20240165401A1

公开(公告)日：2024-05-23

申请号：US18429259

申请日：2024-01-31

Applicant: StimScience Inc.

Inventor： Anantha Pradeep

IPC: A61N1/05 ,  A61B5/00 ,  A61B5/374 ,  A61N1/08 ,  A61N1/36

CPC classification number: A61N1/0534 ,  A61B5/374 ,  A61B5/4812 ,  A61B5/4836 ,  A61N1/36025 ,  A61N1/36078 ,  A61N1/36092 ,  A61N1/36139 ,  A61N1/0531 ,  A61N1/08

Abstract: Provided are systems, methods, and devices for brain stimulation and monitoring. Brain stimulation may be provided to enhance slow wave and spindle synchrony. Such stimulation may provide increased memory consolidation. Furthermore, brain stimulation modalities may provide enhanced sleep and awakening. For example, transcranial direct current stimulation of the brain stimulation may enhance sleep quality. Moreover, one or more markers characterizing unconsciousness are may be identified based on changes in measured power densities or spectra. Further still, the above described modalities of brain stimulation may be implemented in an open-loop or closed loop manner. Brain state parameters may be generated for building models of the brain based on determined synchrony patterns between slow waves and spindles. The models may be used to determine a mediation procedure for adjusting the intensity of slow wave oscillations to enhance slow wave and spindle synchrony.

公开(公告)号：US11986649B2

公开(公告)日：2024-05-21

申请号：US17125793

申请日：2020-12-17

Applicant: StimScience Inc.

Inventor： Anantha K. Pradeep

IPC: A61N1/05 ,  A61B5/00 ,  A61B5/374 ,  A61N1/36 ,  A61N1/08

CPC classification number: A61N1/0534 ,  A61B5/374 ,  A61B5/4812 ,  A61B5/4836 ,  A61N1/36025 ,  A61N1/36078 ,  A61N1/36092 ,  A61N1/36139 ,  A61N1/0531 ,  A61N1/08

Abstract: Provided are systems, methods, and devices for brain stimulation and monitoring. Brain stimulation may be provided to enhance slow wave and spindle synchrony. Such stimulation may provide increased memory consolidation. Furthermore, brain stimulation modalities may provide enhanced sleep and awakening. For example, transcranial direct current stimulation of the brain stimulation may enhance sleep quality. Moreover, one or more markers characterizing unconsciousness are may be identified based on changes in measured power densities or spectra. Further still, the above described modalities of brain stimulation may be implemented in an open-loop or closed loop manner. Brain state parameters may be generated for building models of the brain based on determined synchrony patterns between slow waves and spindles. The models may be used to determine a mediation procedure for adjusting the intensity of slow wave oscillations to enhance slow wave and spindle synchrony.

公开(公告)号：US20240091531A1

公开(公告)日：2024-03-21

申请号：US18254153

申请日：2021-11-23

Applicant: THE UNIVERSITY OF BIRMINGHAM ,  DALHOUSIE UNIVERSITY

Inventor： Sara Assecondi ,  Kimron Lewis Shapiro ,  Gail Ann Eskes

IPC: A61N1/36 ,  A61B5/00 ,  A61B5/374 ,  A61B5/383

CPC classification number: A61N1/36025 ,  A61B5/374 ,  A61B5/383 ,  A61B5/4064 ,  A61N1/36031

Abstract: A system for improving cognitive function is disclosed. The system comprises a non-invasive brain stimulation device (150); a human computer interface; and a computer (101) configured to control the non-invasive brain stimulation device (150) and the human computer interface. The computer (101) controls the brain stimulation device (150) and the human computer interface to assess a subject's baseline cognitive function by interaction with the subject using the human computer interface. If the subject's baseline cognitive function is impaired, the computer (101) uses the human computer interface to provide the subject with a strategy for improving performance in a cognitive function test and stimulates the subjects brain with the non-invasive brain stimulation device (150) while training the subjects cognitive function.

公开(公告)号：US20240032870A1

公开(公告)日：2024-02-01

申请号：US18480239

申请日：2023-10-03

Applicant: NeuroPace, Inc.

Inventor： Felice Sun ,  Rosana Esteller ,  Adam Lee

IPC: A61B5/00 ,  A61N1/36 ,  A61B5/316 ,  A61B5/369 ,  A61B5/374

CPC classification number: A61B5/686 ,  A61B5/7435 ,  A61B5/748 ,  A61N1/36135 ,  A61B5/316 ,  A61B5/369 ,  A61B5/374 ,  A61B5/4094 ,  A61N1/36064 ,  A61B5/4836 ,  A61B5/6868 ,  A61B5/7278 ,  A61B5/7282

Abstract: An initial set of parameters for operating one or more detection tools is automatically derived and subsequently adjusted so that each detection tool is more or less sensitive to signal characteristics in a region of interest. Detection tool(s) may be applied to physiological signals sensed from a patient (such as EEG signals) and may be configured to run in an implanted medical device that is programmable with the parameters to look for rhythmic activity, spiking, and power changes in the sensed signals, etc. A detection tool may be selected and parameter values derived in a logical sequence and/or in pairs based on a graphical representation of an activity type which may be selected by a user, for example, by clicking and dragging on the graphic via a GUI. Displayed simulations allow a user to assess what will be detected with a derived parameter set and then to adjust the sensitivity of the set or start over as desired.