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1.发明申请公开(公告)号：US20170056087A1
公开(公告)日：2017-03-02
申请号：US15229761
申请日：2016-08-05
发明人： Naomi Buckley , Benjamin J. Clark , Michael Cummins , Danny Donovan , Mark Gelfand , Luke Hughes , Brian Kelly , Gary Kelly , Grace Kelly , John Kelly , Mark S. Leung , Gwenda McMullin , Barry Mullins , Karun D. Naga , Stephen Nash , Eric Ryba , Fiachra Sweeney , Vicenzo Tilotta , Roman Turovskiy , Lana Woolley , Denise Zarins , Michael Turovskiy
IPC分类号： A61B18/02
CPC分类号： A61B18/02 , A61B2017/22054 , A61B2017/22067 , A61B2018/00023 , A61B2018/00166 , A61B2018/0022 , A61B2018/00232 , A61B2018/0025 , A61B2018/00261 , A61B2018/00404 , A61B2018/00434 , A61B2018/00511 , A61B2018/00577 , A61B2018/0212 , A61B2018/0262
摘要： Neuromodulation cryotherapeutic devices and associated systems and methods are disclosed herein. A cryotherapeutic device configured in accordance with a particular embodiment of the present technology can include an elongated shaft having distal portion and a supply lumen along at least a portion of the shaft. The shaft can be configured to locate the distal portion intravascularly at a treatment site proximate a renal artery or renal ostium. The supply lumen can be configured to receive a liquid refrigerant. The cryotherapeutic device can further include a cooling assembly at the distal portion of the shaft. The cooling assembly can include an applicator in fluid communication with the supply lumen and configured to deliver cryotherapeutic cooling to nerves proximate the target site when the cooling assembly is in a deployed state.
摘要翻译： 本文公开了神经调节冷冻治疗装置及相关系统和方法。 根据本技术的特定实施例配置的冷冻治疗装置可以包括细长轴，其具有沿轴的至少一部分的远侧部分和供应内腔。 轴可以被配置为将远端部分血管内定位在肾动脉或肾口附近的治疗部位。 供应内腔可被配置为接收液体制冷剂。 冷冻治疗装置还可以包括在轴的远端处的冷却组件。 冷却组件可以包括与供应内腔流体连通的施加器，并且构造成当冷却组件处于展开状态时，将冷冻治疗冷却递送到靠近目标部位的神经。
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公开(公告)号：US20190183556A1
公开(公告)日：2019-06-20
申请号：US16221174
申请日：2018-12-14
发明人： Naomi Buckley , Benjamin J. Clark , Michael Cummins , Danny Donovan , Mark Gelfand , Luke Hughes , Brian Kelly , Gary Kelly , Grace Kelly , John Kelly , Mark S. Leung , Gwenda McMullin , Barry Mullins , Karun D. Naga , Stephen Nash , Eric Ryba , Fiachra Sweeney , Vicenzo Tilotta , Roman Turovskiy , Lana Woolley , Denise Zarins , Michael Turovskiy
IPC分类号： A61B18/02
CPC分类号： A61B18/02 , A61B2017/22054 , A61B2017/22067 , A61B2018/00023 , A61B2018/00166 , A61B2018/0022 , A61B2018/00232 , A61B2018/0025 , A61B2018/00261 , A61B2018/00404 , A61B2018/00434 , A61B2018/00511 , A61B2018/00577 , A61B2018/0212 , A61B2018/0262
摘要： Neuromodulation cryotherapeutic devices and associated systems and methods are disclosed herein. A cryotherapeutic device configured in accordance with a particular embodiment of the present technology can include an elongated shaft having distal portion and a supply lumen along at least a portion of the shaft. The shaft can be configured to locate the distal portion intravascularly at a treatment site proximate a renal artery or renal ostium. The supply lumen can be configured to receive a liquid refrigerant. The cryotherapeutic device can further include a cooling assembly at the distal portion of the shaft. The cooling assembly can include an applicator in fluid communication with the supply lumen and configured to deliver cryotherapeutic cooling to nerves proximate the target site when the cooling assembly is in a deployed state.
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公开(公告)号：US10188445B2
公开(公告)日：2019-01-29
申请号：US15229761
申请日：2016-08-05
发明人： Naomi Buckley , Benjamin J. Clark , Michael Cummins , Danny Donovan , Mark Gelfand , Luke Hughes , Brian Kelly , Gary Kelly , Grace Kelly , John Kelly , Mark S. Leung , Gwenda Francis , Barry Mullins , Karun D. Naga , Stephen Nash , Eric Ryba , Fiachra Sweeney , Vincenzo Tilotta , Roman Turovskiy , Lana Woolley , Denise Zarins , Michael Turovskiy
摘要： Neuromodulation cryotherapeutic devices and associated systems and methods are disclosed herein. A cryotherapeutic device configured in accordance with a particular embodiment of the present technology can include an elongated shaft having distal portion and a supply lumen along at least a portion of the shaft. The shaft can be configured to locate the distal portion intravascularly at a treatment site proximate a renal artery or renal ostium. The supply lumen can be configured to receive a liquid refrigerant. The cryotherapeutic device can further include a cooling assembly at the distal portion of the shaft. The cooling assembly can include an applicator in fluid communication with the supply lumen and configured to deliver cryotherapeutic cooling to nerves proximate the target site when the cooling assembly is in a deployed state.
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公开(公告)号：US20210068886A1
公开(公告)日：2021-03-11
申请号：US17099465
申请日：2020-11-16
发明人： Naomi Buckley , Benjamin J. Clark , Michael Cummins , Danny Donovan , Mark Gelfand , Luke Hughes , Brian Kelly , Gary Kelly , Grace Kelly , John Kelly , Mark S. Leung , Gwenda Francis , Barry Mullins , Karun D. Naga , Stephen Nash , Eric Ryba , Fiachra Sweeney , Vincenzo Tilotta , Roman Turovskiy , Lana Woolley , Denise Zarins , Michael Turovskiy
IPC分类号： A61B18/02
摘要： Neuromodulation cryotherapeutic devices and associated systems and methods are disclosed herein. A cryotherapeutic device configured in accordance with a particular embodiment of the present technology can include an elongated shaft having distal portion and a supply lumen along at least a portion of the shaft. The shaft can be configured to locate the distal portion intravascularly at a treatment site proximate a renal artery or renal ostium. The supply lumen can be configured to receive a liquid refrigerant. The cryotherapeutic device can further include a cooling assembly at the distal portion of the shaft. The cooling assembly can include an applicator in fluid communication with the supply lumen and configured to deliver cryotherapeutic cooling to nerves proximate the target site when the cooling assembly is in a deployed state.
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公开(公告)号：US10004550B2
公开(公告)日：2018-06-26
申请号：US14799743
申请日：2015-07-15
发明人： Eric Ryba , Naomi Buckley , Benjamin J. Clark , Danny Donovan , Luke Hughes , Brian Kelly , Gwenda McMullin , Karun D. Naga , Stephen Nash , Roman Turovskiy , Lana Wooley , Denise Zarins , Mark Gelfand , Mark S. Leung
CPC分类号： A61B18/02 , A61B2018/0022 , A61B2018/0212 , A61B2018/0262 , A61B2018/0268
摘要： Catheter apparatuses, systems, and methods for cryogenically modulating neural structures of the renal plexus by intravascular access are disclosed herein. One aspect of the present application, for example, is directed to apparatuses, systems, and methods that incorporate a catheter treatment device comprising an elongated shaft. The elongated shaft is sized and configured to deliver a cryo-applicator to a renal artery via an intravascular path. Cryogenic renal neuromodulation may be achieved via application of cryogenic temperatures to modulate neural fibers that contribute to renal function, or of vascular structures that feed or perfuse the neural fibers.
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