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    Neuromodulation catheters and associated systems and methods
    1.
    发明授权
    Neuromodulation catheters and associated systems and methods 有权

    公开(公告)号：US11464563B2

    公开(公告)日：2022-10-11

    申请号：US16983408

    申请日：2020-08-03

    申请人： Medtronic Ardian Luxembourg S.a.r.l.

    发明人： Brian Kelly ,  Micheál Moriarty

    IPC分类号： A61B18/14 ,  A61B18/00

    摘要： Methods for treating a patient using therapeutic renal neuromodulation and associated devices, systems, and methods are disclosed herein. One aspect of the present technology, for example, is directed to a catheter apparatus including an elongated shaft defined by a braid embedded within a polymer. The braid can include one or more thermocouple assemblies intertwined with a braiding element. The thermocouple assemblies can be coupled to one or more electrodes at a distal portion of the shaft.

    Cryotherapeutic devices for renal neuromodulation and associated systems and methods
    5.
    发明授权
    Cryotherapeutic devices for renal neuromodulation and associated systems and methods 有权

    公开(公告)号：US10905490B2

    公开(公告)日：2021-02-02

    申请号：US15586666

    申请日：2017-05-04

    申请人： Medtronic Ardian Luxembourg S.a.r.l.

    发明人： Benjamin J. Clark ,  David J. Hobbins ,  Tim Huynh ,  Grace Kelly ,  Brian Kelly

    IPC分类号： A61B18/02 ,  A61B90/00 ,  A61B18/00

    摘要： Cryotherapeutic devices for renal neuromodulation and associated systems and methods are disclosed herein. A cryotherapeutic device configured in accordance with a particular embodiment of the present technology can include an elongated shaft having a distal portion and a supply lumen along at least a portion of the shaft. The shaft can be configured to locate the distal portion intravascularly at a treatment site proximate a renal artery or renal ostium. The supply lumen can be configured to receive a liquid refrigerant. The cryotherapeutic device can further include a cooling assembly at the distal portion of the shaft. The cooling assembly can include an applicator having a distributor in fluid communication with the supply lumen and a balloon configured to deliver cryotherapeutic cooling to nerves proximate the treatment site when the cooling assembly is in a deployed state.

    MONITORING AND CONTROLLING INTERNALLY ADMINISTERED CRYOTHERAPY
    7.
    发明申请
    MONITORING AND CONTROLLING INTERNALLY ADMINISTERED CRYOTHERAPY 有权

    公开(公告)号：US20220361935A1

    公开(公告)日：2022-11-17

    申请号：US17815517

    申请日：2022-07-27

    申请人： MEDTRONIC ARDIAN LUXEMBOURG S.A.R.L.

    发明人： Micheal Moriarty ,  Brian Kelly

    IPC分类号： A61B18/02

    摘要： A method of using a cryotherapeutic system in accordance with a particular embodiment includes advancing an elongate shaft of a catheter toward a treatment location within a body lumen of a human patient and directing a flow of refrigerant toward a cryotherapeutic element at a distal end portion of the shaft. The directed refrigerant is expanded to cause cooling within a balloon of the cryotherapeutic element. The pressure within the balloon is monitored and its rate of change calculated. The rate of change is then processed using different feedback loops during different monitoring windows of a treatment cycle. The individual feedback loops include an upper and a lower threshold and are configured to cause the flow of refrigerant to the cryotherapeutic element to stop if the rate of change falls outside a range between the upper and the lower threshold.

    MONITORING AND CONTROLLING INTERNALLY ADMINISTERED CRYOTHERAPY
    8.
    发明申请
    MONITORING AND CONTROLLING INTERNALLY ADMINISTERED CRYOTHERAPY 审中-公开

    公开(公告)号：US20200085486A1

    公开(公告)日：2020-03-19

    申请号：US16690718

    申请日：2019-11-21

    申请人： Medtronic Ardian Luxembourg S.a.r.l.

    发明人： Micheal Moriarty ,  Brian Kelly

    IPC分类号： A61B18/02

    摘要： A method of using a cryotherapeutic system in accordance with a particular embodiment includes advancing an elongate shaft of a catheter toward a treatment location within a body lumen of a human patient and directing a flow of refrigerant toward a cryotherapeutic element at a distal end portion of the shaft. The directed refrigerant is expanded to cause cooling within a balloon of the cryotherapeutic element. The pressure within the balloon is monitored and its rate of change calculated. The rate of change is then processed using different feedback loops during different monitoring windows of a treatment cycle. The individual feedback loops include an upper and a lower threshold and are configured to cause the flow of refrigerant to the cryotherapeutic element to stop if the rate of change falls outside a range between the upper and the lower threshold.