公开(公告)号：US10517892B2

公开(公告)日：2019-12-31

申请号：US14512788

申请日：2014-10-13

申请人： Medtronic MiniMed, Inc.

发明人： Sarnath Chattaraj ,  Kiem H. Dang ,  Hsi Chung Fusselman ,  Poonam S. Gulati ,  Lance P. Hoffman ,  Guangping Zhang

IPC分类号： A61K31/727 ,  A61M5/142 ,  A61K38/28 ,  A61L29/08 ,  A61L29/16 ,  A61M5/158 ,  A61M5/168

摘要： Methods and devices are provided for reducing a diabetic patient's foreign body immune response, including infusion site-loss and/or occlusion. Such foreign body responses are associated with the treatment of the diabetic patient where the treatment requires subcutaneous implantation of a foreign body, such as a cannula or catheter. In certain embodiments of the invention, a response-inhibiting agent is administered to a patient at the site of cannula/catheter insertion, thereby facilitating delivery of insulin to the diabetic patient and mitigating site-loss and/or occlusion over a period of time.

公开(公告)号：US10279126B2

公开(公告)日：2019-05-07

申请号：US14508934

申请日：2014-10-07

申请人： MEDTRONIC MINIMED, INC.

发明人： Sarnath Chattaraj ,  Kiem H. Dang ,  Poonam S. Gulati ,  Guangping Zhang

IPC分类号： A61M5/38 ,  A61M5/162 ,  A61M5/142 ,  A61M39/10

摘要： A fluid delivery system and a fluid conduit assembly suitable for use with the system are disclosed herein. The system includes a fluid infusion pump and a fluid conduit assembly coupled to the pump to deliver medication fluid to a user. The fluid conduit assembly includes a structure defining a flow path for the medication fluid, and a gas trapping filter coupled to the structure and positioned in the flow path. The gas trapping filter functions to filter particulates from the medication fluid and retain gas bubbles from the medication fluid.

公开(公告)号：US20240001046A1

公开(公告)日：2024-01-04

申请号：US18469739

申请日：2023-09-19

申请人： MEDTRONIC MINIMED, INC.

发明人： Sarnath Chattaraj ,  Kiem H. Dang ,  Poonam S. Gulati ,  Guangping Zhang

IPC分类号： A61M5/38 ,  A61M5/162 ,  A61M5/142 ,  A61M39/10

CPC分类号： A61M5/38 ,  A61M5/162 ,  A61M5/142 ,  A61M39/10 ,  A61M5/14244

摘要： A fluid delivery system and a fluid conduit assembly suitable for use with the system are disclosed herein. The system includes a fluid infusion pump and a fluid conduit assembly coupled to the pump to deliver medication fluid to a user. The fluid conduit assembly includes a structure defining a flow path for the medication fluid, and a gas trapping filter coupled to the structure and positioned in the flow path. The gas trapping filter functions to filter particulates from the medication fluid and retain gas bubbles from the medication fluid.

公开(公告)号：US11439352B2

公开(公告)日：2022-09-13

申请号：US16248623

申请日：2019-01-15

申请人： MEDTRONIC MINIMED, INC.

发明人： Matthew William Yavorsky ,  Sarnath Chattaraj ,  Kiem H. Dang ,  Guangping Zhang

IPC分类号： A61B5/00 ,  A61B5/145 ,  A61M5/158 ,  A61B5/1486 ,  A61M39/00 ,  A61M5/14 ,  A61M39/02

摘要： A medical device includes a hub and an adhesive patch coupled to the hub. The adhesive patch is to couple the hub to an anatomy. The adhesive patch defines an edge that extends along a perimeter of the adhesive patch. The medical device includes an anisotropic shim coupled to the adhesive patch along the perimeter of the adhesive patch proximate the edge to resist an uncoupling of the adhesive patch from the anatomy. The anisotropic shim has an inner periphery spaced apart from an outer periphery and the anisotropic shim is locally rigid between the inner periphery and the outer periphery.

公开(公告)号：US20190336078A1

公开(公告)日：2019-11-07

申请号：US16400878

申请日：2019-05-01

申请人： MEDTRONIC MINIMED, INC.

发明人： Kiem Dang ,  Sarnath Chattaraj ,  Hsi C. Fusselman ,  Guangping Zhang

IPC分类号： A61B5/00 ,  A61B5/1486 ,  A61M5/142 ,  A61B5/145

摘要： An adhesive patch for a medical device having a hub, such as an infusion device, is provided. The adhesive patch includes a first backing layer to be coupled to the medical device. The first backing layer is composed of a first material. The adhesive patch includes a first adhesive layer coupled to the first backing layer and a second backing layer coupled to the first adhesive layer. The second backing layer is composed of a second material, and the second material is different than the first material. The adhesive patch includes a biocompatible second adhesive layer coupled to the second backing layer, and the second adhesive layer is to be coupled to an anatomy.

公开(公告)号：US20180200412A1

公开(公告)日：2018-07-19

申请号：US15874757

申请日：2018-01-18

申请人： Medtronic MiniMed, Inc.

发明人： Kiem H. Dang ,  Sarnath Chattaraj ,  Hsi C. Fusselman ,  Lance P. Hoffman ,  Guangping Zhang

IPC分类号： A61L29/14 ,  A61K9/00 ,  A61K38/28 ,  A61K31/727 ,  A61L29/04 ,  A61M5/142 ,  A61M5/158 ,  A61M5/38

CPC分类号： A61L29/146 ,  A61K9/0019 ,  A61K31/727 ,  A61K38/28 ,  A61L29/049 ,  A61M5/142 ,  A61M5/14248 ,  A61M5/14276 ,  A61M5/158 ,  A61M5/38 ,  A61M39/10 ,  A61M39/162 ,  A61M2005/1586 ,  A61M2205/0272 ,  A61M2205/3334 ,  A61M2205/584 ,  A61M2205/7545 ,  A61M2207/00 ,  A61M2230/201

摘要： This invention pertains to systems and components useful for infusing medications such as insulin. Typically, the components are used to deliver insulin to a diabetic patient at a site of infusion over a period of time greater than 4 days. The system components typically comprise a cannula adapted for subcutaneous insertion into a diabetic patient. The system further comprises a fluid conduit adapted to deliver the insulin solution from a medication reservoir to the site of infusion and a depot in operable contact with the fluid conduit. The depot comprises selected materials including a site-loss mitigating agent (such as heparin) which inhibits inflammation at the site of infusion, and encapsulation of the cannula at the site of infusion. The site-loss mitigating agent is not premixed with the insulin, and instead is adapted to contact the insulin solution in the depot as the insulin solution flows from the medication reservoir to the site of infusion.

公开(公告)号：US20160095987A1

公开(公告)日：2016-04-07

申请号：US14508934

申请日：2014-10-07

申请人： MEDTRONIC MINIMED, INC.

发明人： Sarnath Chattaraj ,  Kiem H. Dang ,  Poonam S. Gulati ,  Guangping Zhang

IPC分类号： A61M5/38 ,  A61M5/142 ,  A61M39/10 ,  A61M5/162

CPC分类号： A61M5/38 ,  A61M5/142 ,  A61M5/14244 ,  A61M5/162 ,  A61M39/10

摘要： A fluid delivery system and a fluid conduit assembly suitable for use with the system are disclosed herein. The system includes a fluid infusion pump and a fluid conduit assembly coupled to the pump to deliver medication fluid to a user. The fluid conduit assembly includes a structure defining a flow path for the medication fluid, and a gas trapping filter coupled to the structure and positioned in the flow path. The gas trapping filter functions to filter particulates from the medication fluid and retain gas bubbles from the medication fluid.

摘要翻译： 本文公开了适用于该系统的流体输送系统和流体导管组件。 该系统包括流体输注泵和连接到泵的流体导管组件，以向使用者输送药物流体。 流体导管组件包括限定用于药物流体的流动路径的结构以及耦合到结构并且定位在流动路径中的气体捕获过滤器。 气体捕集过滤器用于过滤来自药物流体的颗粒并保留来自药物流体的气泡。

公开(公告)号：US11786673B2

公开(公告)日：2023-10-17

申请号：US17374226

申请日：2021-07-13

申请人： MEDTRONIC MINIMED, INC.

发明人： Sarnath Chattaraj ,  Kiem H. Dang ,  Poonam S. Gulati ,  Guangping Zhang

IPC分类号： A61M5/38 ,  A61M5/162 ,  A61M5/142 ,  A61M39/10

CPC分类号： A61M5/38 ,  A61M5/142 ,  A61M5/14244 ,  A61M5/162 ,  A61M39/10

摘要： A fluid delivery system and a fluid conduit assembly suitable for use with the system are disclosed herein. The system includes a fluid infusion pump and a fluid conduit assembly coupled to the pump to deliver medication fluid to a user. The fluid conduit assembly includes a structure defining a flow path for the medication fluid, and a gas trapping filter coupled to the structure and positioned in the flow path. The gas trapping filter functions to filter particulates from the medication fluid and retain gas bubbles from the medication fluid.

公开(公告)号：US11197949B2

公开(公告)日：2021-12-14

申请号：US15874757

申请日：2018-01-18

申请人： Medtronic MiniMed, Inc.

发明人： Kiem H. Dang ,  Sarnath Chattaraj ,  Hsi C. Fusselman ,  Lance P. Hoffman ,  Guangping Zhang

IPC分类号： A61L29/14 ,  A61K38/28 ,  A61K31/727 ,  A61L29/04 ,  A61M5/142 ,  A61M5/38 ,  A61K9/00 ,  A61M39/10 ,  A61M39/16 ,  A61M5/158

摘要： This invention pertains to systems and components useful for infusing medications such as insulin. Typically, the components are used to deliver insulin to a diabetic patient at a site of infusion over a period of time greater than 4 days. The system components typically comprise a cannula adapted for subcutaneous insertion into a diabetic patient. The system further comprises a fluid conduit adapted to deliver the insulin solution from a medication reservoir to the site of infusion and a depot in operable contact with the fluid conduit. The depot comprises selected materials including a site-loss mitigating agent (such as heparin) which inhibits inflammation at the site of infusion, and encapsulation of the cannula at the site of infusion. The site-loss mitigating agent is not premixed with the insulin, and instead is adapted to contact the insulin solution in the depot as the insulin solution flows from the medication reservoir to the site of infusion.

公开(公告)号：US20210146047A1

公开(公告)日：2021-05-20

申请号：US16687481

申请日：2019-11-18

申请人： MEDTRONIC MINIMED, INC.

发明人： Guangping Zhang ,  Kiem H. Dang ,  Valerie Chen ,  Ling Jiang ,  Evan Anselmo ,  Zhiwu Fang ,  Sarnath Chattaraj

IPC分类号： A61M5/172 ,  A61M5/142 ,  A61M5/14 ,  A61M5/168

摘要： Disclosed herein are combined devices and methods of manufacturing such combined devices. The combined devices disclosed herein include an analyte sensor including a sensor probe; an infusion set hub including a cannula; and a flexible base. The analyte sensor and infusion set hub are attached to the flexible base such that movement of one of the analyte sensor and the infusion set hub is substantially not transferred to the other one of the analyte sensor and the infusion set hub.