公开(公告)号：US20070243290A1

公开(公告)日：2007-10-18

申请号：US11406091

申请日：2006-04-18

申请人： Melody Thompson ,  Sandra Weida ,  Bridget Barrett-Reis ,  Terrence Mazer

发明人： Melody Thompson ,  Sandra Weida ,  Bridget Barrett-Reis ,  Terrence Mazer

IPC分类号： A23L1/30

CPC分类号： A23L33/16 ,  A23L33/10 ,  A23L33/15 ,  A23L33/30 ,  A23L33/40 ,  A23V2002/00 ,  A23V2250/1578 ,  A23V2250/1642 ,  A23V2250/1588 ,  A23V2250/1614 ,  A23V2250/702 ,  A23V2250/71 ,  A23V2250/7056 ,  A23V2250/7046 ,  A23V2250/705 ,  A23V2250/706 ,  A23V2250/708

摘要： Disclosed is a method of tailoring infant formulas to individual nutrition needs prior to use. The method comprises (A) determining the desired volume and optimal caloric density of a formula to be fed to a preterm or low birth weight infant; (B) obtaining a plurality of base infant formulas, all in liquid form, comprising fat, protein, carbohydrate, vitamins, and minerals, each of which has an osmolality of from about 200 to about 360 mOsm/kg water and a different caloric density within a range of from about 609 to about 1082 kcal/L; (C) selecting two of the base liquid formulas having a caloric density value above and below the optimal caloric density, (D) calculating the volume of each selected base formula needed to produce the desired volume of an infant formula blend having the optimal caloric density; (E) combining the calculated volumes to produce a an isotonic blend having the desired feeding volume and optimal caloric density. The formula is then fed to the preterm or low birth weight infant. Also disclosed is a hypercaloric infant formula suitable for use in the disclosed method, and infant formula kits comprising the plurality of base formulas and a device (e.g. calculator, computer program, chart with precalculated blend volumes) for calculating blend volumes.

摘要翻译： 公开了一种在使用前将婴儿配方调配到个体营养需求的方法。 该方法包括（A）确定要喂给早产或低出生体重婴儿的配方的期望体积和最佳热量密度; （B）获得多种液体形式的基础婴儿配方食品，包括脂肪，蛋白质，碳水化合物，维生素和矿物质，其各自具有约200至约360mOsm / kg水的重量摩尔渗透压浓度和不同的热量密度 在约609至约1082kcal / L的范围内; （C）选择具有高于和低于最佳热量密度的热量密度值的两种基础液体配方，（D）计算产生具有最佳热量密度的婴儿配方配方所需体积所需的每种所选碱基配方的体积 ; （E）组合计算的体积以产生具有所需进料体积和最佳热量密度的等渗混合物。 然后将该配方喂给早产或低出生体重的婴儿。 还公开了适用于所公开的方法的超热量婴儿配方食品，以及包含多种基础配方的婴儿配方药盒和用于计算混合体积的装置（例如计算器，计算机程序，具有预先计算的混合物体积的图表）。

公开(公告)号：US20060204632A1

公开(公告)日：2006-09-14

申请号：US11370610

申请日：2006-03-08

申请人： Bridget Barrett-Reis ,  Cynthia Black ,  Terrence Mazer

发明人： Bridget Barrett-Reis ,  Cynthia Black ,  Terrence Mazer

IPC分类号： A23C9/154

CPC分类号： A23C9/206 ,  A23L33/18 ,  A23L33/185 ,  A23L33/19 ,  A23L33/40 ,  A23V2002/00 ,  A23V2250/1578 ,  A23V2250/1642 ,  A23V2250/1592 ,  A23V2250/1588 ,  A23V2250/1612 ,  A23V2250/1626 ,  A23V2250/1598 ,  A23V2250/702 ,  A23V2250/704 ,  A23V2250/71 ,  A23V2250/712 ,  A23V2250/714 ,  A23V2250/628 ,  A23V2250/54252 ,  A23V2250/5424 ,  A23V2250/1944 ,  A23V2250/1868 ,  A23V2250/1842 ,  A23V2250/1862 ,  A23V2250/70 ,  A23V2250/0644 ,  A23V2250/641 ,  A23V2250/54246

摘要： Disclosed are concentrated, liquid, human milk fortifier compositions comprising from about 15% to about 45% by weight of protein, on a dry weight basis, and having a caloric density of from about 1.25 kcauml to about 6.0 kcau/ml, wherein the liquid human milk fortifier composition is added to human milk in a volume-volume ratio of from about 1:3 to about 1:9. These composition include embodiments comprising carbohydrate and fat, that are formulated with improved stability by selecting any one of the following variations: 1) certain whey-casein protein blends, 2) water insoluble calcium-containing materials, 3) protein hydrolysates, and 4) aseptically packaged concentrates. The liquid concentrates are especially useful for providing nutrition to preterm infants in neonatal intensive care units or similar other institutional setting, and to minimize the risk of introducing microbial contaminants such as Enterobacter sakazakii to infant feedings during preparation in such institutional settings.

摘要翻译： 本发明公开了浓缩液体，人乳增强剂组合物，其包含按重量计约15％至约45％重量的蛋白质，其热密度为约1.25kcal / ml至约6.0kcau / ml，其中液体 将人乳强化剂组合物以体积比体积比为约1:3至约1:9添加到人乳中。 这些组合物包括含有碳水化合物和脂肪的实施方案，通过选择以下变化之一来改进稳定性：1）某些乳清酪蛋白混合物，2）水不溶性含钙材料，3）蛋白质水解产物，和4） 无菌包装浓缩液。 液体浓缩物特别适用于为新生儿重症监护病房或类似的其他机构环境中的早产儿提供营养，并且在制备过程中尽可能减少将阪崎肠杆菌等微生物污染物引入婴儿喂养的风险。

公开(公告)号：US20080063753A1

公开(公告)日：2008-03-13

申请号：US11851473

申请日：2007-09-07

申请人： Normanella DeWille ,  Judith Atkinson ,  Neile Edens ,  Terrence Mazer ,  Kelley Lowe ,  Douglas Wearly ,  Allison Ogilvie

发明人： Normanella DeWille ,  Judith Atkinson ,  Neile Edens ,  Terrence Mazer ,  Kelley Lowe ,  Douglas Wearly ,  Allison Ogilvie

IPC分类号： A23L1/10 ,  A23L1/105

CPC分类号： A23L7/126 ,  A23L7/122 ,  A23P20/12 ,  A23P20/18 ,  A23P20/20 ,  A23V2002/00 ,  A23V2200/22 ,  A23V2200/328 ,  A23V2250/606

摘要： The present invention provides a food product comprising: a formed reduced glycemic response cereal component; and a non-sticky reduced glycemic response sweetener coating over the formed cereal component, the sweetener coating comprising: a first sticky layer comprising at least about 30% fructose (of the total sweetener coating); a second less sticky layer having a DE value of about 60 or less and comprising up to about 17% fructose and at least about 1% non-fructose carbohydrates (of the total sweetener coating); and third layer comprising crystalline fructose. The present invention also provides a process for forming the sweetener coating over the formed cereal component comprising the following steps: (a) providing a formed cereal component having thereon a first sticky layer comprising fructose; (b) forming over the first sticky layer a less stick second layer comprising non-fructose carbohydrates and optionally fructose; and (c) applying crystalline fructose over the second layer.

摘要翻译： 本发明提供一种食品，其包含：形成的降低的血糖反应谷物成分; 和在形成的谷物成分上的非粘性降低的血糖响应甜味剂涂层，所述甜味剂涂层包含：包含至少约30％的果糖（总甜味剂包衣的）的第一粘性层; DE值为约60或更小的第二较低粘性层，包含高达约17％的果糖和至少约1％的非果糖碳水化合物（总甜味剂涂层）; 和包含结晶果糖的第三层。 本发明还提供了一种用于在所形成的谷物成分上形成甜味剂涂层的方法，包括以下步骤：（a）提供形成有谷物成分的谷物成分，其上含有果糖的第一粘性层; （b）在第一粘性层上形成较少的第二层，其包含非果糖碳水化合物和任选的果糖; 和（c）在第二层上施加结晶果糖。

公开(公告)号：US20050085632A1

公开(公告)日：2005-04-21

申请号：US10929334

申请日：2004-08-27

申请人： Paul Johns ,  Andre Daab-Krzykowski ,  Terrence Mazer ,  John Suh

发明人： Paul Johns ,  Andre Daab-Krzykowski ,  Terrence Mazer ,  John Suh

IPC分类号： C07H15/00 ,  C07F9/02 ,  C07D311/76

CPC分类号： C07H15/00

摘要： Methods for sequentially removing isoflavones and phytates from an active surface by utilizing an aqueous medium for isoflavone removal and an aqueous medium for phytate removal. The aqueous medium for isoflavone removal contains at least one alcohol and at least one acid. The aqueous medium for phytate removal is either a relatively stronger acidic solution, a basic solution, or with some active surfaces may be an aqueous solution of pH 2-7, which is essentially free of alcohol and organic solvents. The use of the methods disclosed allows sequential isolation of isoflavones and phytates, compounds which may then be utilized in various foods for human consumption.

摘要翻译： 通过使用去除异黄酮的水性介质和去除植酸盐的水性介质从活性表面依次除去异黄酮和植酸盐的方法。 用于异黄酮去除的水性介质含有至少一种醇和至少一种酸。 去除植酸盐的水性介质是相对较强的酸性溶液，碱性溶液，或者与一些活性表面可以是pH2-7的水溶液，其基本上不含醇和有机溶剂。 使用所公开的方法允许顺序分离异黄酮和植酸盐，然后可以将其用于各种食物用于人类消费。

公开(公告)号：US20070225348A1

公开(公告)日：2007-09-27

申请号：US11385302

申请日：2006-03-21

申请人： Neile Edens ,  Marti Bergana ,  Kati Shearer ,  Terrence Mazer ,  Joseph Walton ,  David Wolf

发明人： Neile Edens ,  Marti Bergana ,  Kati Shearer ,  Terrence Mazer ,  Joseph Walton ,  David Wolf

IPC分类号： A61K31/4172 ,  A61K31/405 ,  A61K31/401 ,  A61K31/198

CPC分类号： A61K31/223 ,  A61K31/198 ,  A61K31/401 ,  A61K31/405 ,  A61K31/4172 ,  A61K2300/00 ,  Y10S514/866

摘要： Disclosed are compositions, including low-calorie beverages or liquids, comprising isoleucine, leucine, valine, cysteine, and methionine, in specified amounts, weight ratios, or both. The compositions are especially useful in treating individuals afflicted with impaired glucose tolerance or diabetes.

摘要翻译： 公开了包含特定量，重量比或两者的异亮氨酸，亮氨酸，缬氨酸，半胱氨酸和甲硫氨酸的组合物，包括低热量饮料或液体。 该组合物特别可用于治疗患有葡萄糖耐量降低或糖尿病的个体。

公开(公告)号：US20060034944A1

公开(公告)日：2006-02-16

申请号：US11117236

申请日：2005-04-28

申请人： Keith Rushlow ,  Robert Shalwitz ,  Terrence Mazer ,  Normanella Dewille ,  Tapas Das ,  Anand Seth

发明人： Keith Rushlow ,  Robert Shalwitz ,  Terrence Mazer ,  Normanella Dewille ,  Tapas Das ,  Anand Seth

IPC分类号： A61K36/30 ,  A61K36/064 ,  A61K31/202 ,  A61K31/198 ,  A61K33/04

CPC分类号： A61K36/30 ,  A23L33/12 ,  A23L33/15 ,  A23L33/165 ,  A23L33/40 ,  A23V2002/00 ,  A61K31/198 ,  A61K31/202 ,  A61K33/04 ,  A61K36/064 ,  A61K2300/00 ,  A23V2250/5424 ,  A23V2250/1578 ,  A23V2250/1882 ,  A23V2250/1842 ,  A23V2250/1598 ,  A23V2200/308 ,  A23V2250/714 ,  A23V2250/7106 ,  A23V2250/712 ,  A23V2250/1874

摘要： Disclosed are compositions and corresponding methods for treating fibrocystic breast disease or other breast-related disease or condition. The compositions comprise, per serving or dose, from zero to about 400 μg selenium, from about 100 mg to about 6000 mg gamma linolenic acid, and about 0.15 mg to about 5 mg iodine, with nutritional embodiments further comprising one or more of protein, fat, carbohydrate, vitamins, and minerals and providing from about 50 to about 1000 kcal of energy per severing or dose. Also disclosed are in-vitro studies showing that certain combinations of gamma linolenic acid, iodine, and/or selenium may 1) inhibit breast cancer or fibrocystic cell proliferation, 2) reinforce the function of tight junctions of endothelial cells and of mammary epithelial cells in estrogen-sensitive conditions, and 3) reduce the risk of vascular invasion by breast cancer cells.

摘要翻译： 公开了治疗纤维囊性乳腺疾病或其它乳腺相关疾病或病症的组合物和相应的方法。 该组合物每份或剂量包含从0至约400杯硒，约100mg至约6000mgγ亚麻酸和约0.15mg至约5mg的碘，营养实施方案还包含一种或多种蛋白质， 脂肪，碳水化合物，维生素和矿物质，并且每切断或剂量提供约50至约1000千卡的能量。 还公开了体外研究，显示γ亚麻酸，碘和/或硒的某些组合可以1）抑制乳腺癌或纤维囊性细胞增殖，2）增强内皮细胞和乳腺上皮细胞紧密连接的功能 雌激素敏感条件，以及3）降低乳腺癌细胞血管侵袭的风险。