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公开(公告)号:US20190151451A1
公开(公告)日:2019-05-23
申请号:US16256463
申请日:2019-01-24
Applicant: Merial, Inc.
Inventor: Noel Yves Henri Jean Genin
IPC: A61K47/26 , A61K9/20 , A61K39/00 , A61K9/00 , A61K39/275 , A61K39/255 , A61K9/46 , A61K39/12 , A61K39/215 , A61K39/17
Abstract: The present invention relates to novel stable compressed vaccine composition composing at least one anhydrous antigenic component comprising a stabilizer susceptible to foaming when the composition is mixed with liquid diluent; and an effective amount of a sugar alcohol.
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公开(公告)号:US20190070117A1
公开(公告)日:2019-03-07
申请号:US16182868
申请日:2018-11-07
Applicant: Merial, Inc.
Inventor: Noel Yves Henri Jean Genin
Abstract: The present invention relates generally to the fields of immunology and vaccine technology. More specifically, the present invention relates to methods for vitrifying biological preparations, including peptides, antigens, antibodies, cells, and the like.
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公开(公告)号:US10213509B2
公开(公告)日:2019-02-26
申请号:US16125911
申请日:2018-09-10
Applicant: Merial, Inc.
Inventor: Noel Yves Henri Jean Genin
IPC: A61K47/26 , A61K9/46 , A61K9/00 , A61K39/00 , A61K39/12 , A61K39/17 , A61K39/215 , A61K39/255 , A61K39/275 , A61K9/20
Abstract: The present invention relates to novel stable compressed vaccine composition comprising at least one anhydrous antigenic component comprising a stabilizer susceptible to foaming when the composition is mixed with liquid diluent; and an effective amount of a sugar alcohol.
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公开(公告)号:US20170087230A1
公开(公告)日:2017-03-30
申请号:US15311093
申请日:2015-05-13
Applicant: MERIAL INC. , VITAMFERO S.A , L'UNIVERSITE DE BOURGOGNE , L'Institut National Superieur des Sciences Agronomiques de L'Alimentation et de L'Environmen
Inventor: Noel Yves Henri Jean Genin , Jean-Christophe Audonnet , Didier Roy , Edouard Seche , Patrick Gervais , Samira Khaldi-Plassart , Romain Useo , Joelle DeConinck
IPC: A61K39/002 , A61K9/19 , A01N1/02
CPC classification number: A61K39/002 , A01N1/02 , A01N1/0221 , A01N1/0278 , A01N1/0284 , A61K9/0019 , A61K9/19 , A61K2039/522 , Y02A50/41 , Y02A50/412
Abstract: The present invention relates generally to the fields of immunology and vaccine technology. More specifically, the present invention relates to methods for freeze-drying biological preparations, including peptides, antigens, antibodies, and especially, cells. Importantly, the disclosed methods preserve the viability, infectivity and immunogenicity of cells from the Apicomplexa phylum, the Sarcocystidae family, and in particular, cells from the Toxoplasma genus.
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公开(公告)号:US20190000978A1
公开(公告)日:2019-01-03
申请号:US16125911
申请日:2018-09-10
Applicant: Merial, Inc.
Inventor: Noel Yves Henri Jean Genin
IPC: A61K47/26 , A61K9/20 , A61K39/00 , A61K39/275 , A61K39/255 , A61K39/215 , A61K39/17 , A61K39/12 , A61K9/46 , A61K9/00
Abstract: The present invention relates to novel stable compressed vaccine composition comprising least one anhydrous antigenic component comprising a stabilizer susceptible to foaming when the composition is mixed with liquid diluent; and an effective amount of a sugar alcohol.
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公开(公告)号:US10188734B2
公开(公告)日:2019-01-29
申请号:US14880145
申请日:2015-10-09
Applicant: Merial Inc.
Inventor: Noel Yves Henri Jean Genin
IPC: A61K47/26 , A61K39/00 , A61K39/12 , A61K39/17 , A61K39/215 , A61K39/255 , A61K39/275 , A61K9/20 , A61K9/46 , A61K9/00
Abstract: The present invention relates to novel stable compressed vaccine composition comprising at least one anhydrous antigenic component comprising a stabilizer susceptible to foaming when the composition is mixed with liquid diluent; and an effective amount of a sugar alcohol.
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公开(公告)号:US20160256554A1
公开(公告)日:2016-09-08
申请号:US14880145
申请日:2015-10-09
Applicant: Merial Inc.
Inventor: Noel Yves Henri Jean Genin
IPC: A61K47/26 , A61K39/215 , A61K39/17
CPC classification number: A61K47/26 , A61K9/0007 , A61K9/0056 , A61K9/2009 , A61K9/2013 , A61K9/2018 , A61K9/2063 , A61K39/00 , A61K39/12 , A61K39/17 , A61K39/215 , A61K39/255 , A61K39/275 , A61K2039/5252 , A61K2039/552 , C12N2760/18134 , C12N2770/20034
Abstract: The present invention relates to novel stable compressed vaccine composition comprising at least one anhydrous antigenic component comprising a stabilizer susceptible to foaming when the composition is mixed with liquid diluent; and an effective amount of a sugar alcohol.
Abstract translation: 本发明涉及新颖的稳定的压缩疫苗组合物,其包含至少一种无水抗原成分,当组合物与液体稀释剂混合时,其包含易发泡的稳定剂; 和有效量的糖醇。
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