公开(公告)号：US20230141860A1

公开(公告)日：2023-05-11

申请号：US17930513

申请日：2022-09-08

Applicant: Meso Scale Technologies, LLC.

Inventor： Seth B. HARKINS ,  Timothy J. BREAK

IPC: C12Q1/6818

CPC classification number: C12Q1/6818 ,  C12Q2600/16 ,  C12Q1/6837

Abstract: Described herein is a method for detecting an oligonucleotide in a sample, and in particular, to a method for detecting sense and antisense strands of an oligonucleotide duplex in a sample.

公开(公告)号：US20220404360A1

公开(公告)日：2022-12-22

申请号：US17749716

申请日：2022-05-20

Applicant: Meso Scale Technologies, LLC.

Inventor： George SIGAL ,  Seth B. HARKINS ,  Timothy J. BREAK

IPC: G01N33/569 ,  C12Q1/6818 ,  G16B25/10 ,  G16B30/00

Abstract: The invention relates to methods and kits for determining a SARS-CoV-2 strain in a sample. The invention also provides methods and kits for detecting a single nucleotide polymorphism (SNP) in a target nucleic acid, wherein the target nucleic acid is a SARS-CoV-2 nucleic acid. The invention further provides methods and kits for detecting one or more antibody biomarkers in a sample.

公开(公告)号：US20220003766A1

公开(公告)日：2022-01-06

申请号：US17246360

申请日：2021-04-30

Applicant: Meso Scale Technologies, LLC.

Inventor： Jacob N. WOHLSTADTER ,  George SIGAL ,  Anu MATHEW ,  Anastasia AKSYUK ,  David ROUTENBERG ,  Martin STENGELIN ,  John KENTEN ,  Timothy J. BREAK ,  Seth B. HARKINS ,  Michael TSIONSKY

IPC: G01N33/569 ,  C12Q1/70

Abstract: The invention relates to methods and kits for detecting a virus, e.g., a respiratory virus such as a coronavirus, in a biological sample. The invention also relates to methods and kits for detecting and/or quantifying biomarkers, e.g., antibody biomarkers against a viral antigen; inflammatory and/or tissue damage response biomarkers; and/or extracellular vesicles in response to a viral infection.

公开(公告)号：US20240368676A1

公开(公告)日：2024-11-07

申请号：US18043275

申请日：2021-09-02

Applicant: Meso Scale Technologies, LLC.

Inventor： John H. KENTEN ,  Galina NIKOLENKO ,  Seth B. HARKINS ,  Timothy J. BREAK

IPC: C12Q1/682

Abstract: Oligonucleotides, methods and kits are provided for detecting, identifying or quantifying one or more target analytes in a sample as well as methods for immobilizing oligonucleotides onto a support surface.

公开(公告)号：US20230175043A1

公开(公告)日：2023-06-08

申请号：US17607731

申请日：2020-04-30

Applicant: Meso Scale Technologies, LLC.

Inventor： John KENTEN ,  Sudeep KUMAR ,  Galina NIKOLENKO ,  Laukik SARDESAI ,  Alexander K. TUCKER-SCHWARTZ ,  George SIGAL ,  Seth Beebe HARKINS ,  Robert UMEK ,  Timothy J. BREAK ,  Laure MOLLER

IPC: C12Q1/6825

CPC classification number: C12Q1/6825 ,  C12Q1/6837 ,  C12Q2600/16

Abstract: Oligonucleotides, methods and kits are provided for detecting, identifying or quantifying one or more target analytes in a sample as well as methods for immobilizing oligonucleotides onto a support surface.