Polymer Coatings Containing Drug Powder Of Controlled Morphology

    公开(公告)号:US20210161687A1

    公开(公告)日:2021-06-03

    申请号:US17157115

    申请日:2021-01-25

    IPC分类号: A61F2/82 A61L31/10 A61L31/16

    摘要: A method for depositing a coating comprising a polymer and pharmaceutical agent on a substrate, comprising the following steps: discharging at least one pharmaceutical agent in a therapeutically desirable morphology in dry powder form through a first orifice; discharging at least one polymer in dry powder form through a second orifice; depositing the polymer and/or pharmaceutical particles onto said substrate, wherein an electrical potential is maintained between the substrate and the pharmaceutical and/or polymer particles, thereby forming said coating; and sintering said coating under conditions that do not substantially modify the morphology of said pharmaceutical agent.

    Polymer coatings containing drug powder of controlled morphology

    公开(公告)号:US10898353B2

    公开(公告)日:2021-01-26

    申请号:US15705489

    申请日:2017-09-15

    IPC分类号: A61F2/82 A61L31/10 A61L31/16

    摘要: A method for depositing a coating comprising a polymer and pharmaceutical agent on a substrate, comprising the following steps: discharging at least one pharmaceutical agent in a therapeutically desirable morphology in dry powder form through a first orifice; discharging at least one polymer in dry powder form through a second orifice; depositing the polymer and/or pharmaceutical particles onto said substrate, wherein an electrical potential is maintained between the substrate and the pharmaceutical and/or polymer particles, thereby forming said coating; and sintering said coating under conditions that do not substantially modify the morphology of said pharmaceutical agent.