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1.发明授权Methods and devices for the treatment of airway obstruction, sleep apnea and snoring 有权用于治疗气道阻塞，睡眠呼吸暂停和打鼾的方法和装置公开(公告)号：US08371307B2
公开(公告)日：2013-02-12
申请号：US11835966
申请日：2007-08-08
申请人： Mark Hirotsuka , Jasper Jackson , Damien Shulock , Andrew Frazier , Chad Roue , Erik van der Burg , Michael Dineen
发明人： Mark Hirotsuka , Jasper Jackson , Damien Shulock , Andrew Frazier , Chad Roue , Erik van der Burg , Michael Dineen
IPC分类号： A61F5/56
CPC分类号： A61F5/566 , A61B17/0401 , A61B17/0642 , A61B17/24 , A61B2017/00862 , A61B2017/00867 , A61B2017/044 , A61B2017/06176
摘要： Methods and devices for the treatment of airway obstruction, sleep apnea and snoring are disclosed. In some embodiments, a glossal suspension system includes a tissue tensioner that includes a suture loop made of one or more sutures configured to suspend the tongue with at least one portion configured to extend laterally through the tongue, and a securement mechanism configured to be attached to a patient's mandible that includes one more adjustment assemblies for engaging the one or more sutures and adjusting tension on the suture loop. Various tethers and anchors that can be used with the glossal suspension system are also disclosed.
摘要翻译： 公开了治疗气道阻塞，睡眠呼吸暂停和打鼾的方法和装置。 在一些实施例中，光泽悬挂系统包括组织张紧器，该组织张紧器包括由一个或多个缝合线构成的缝合线圈，所述缝合线圈被配置为使至少一部分被配置成横向延伸穿过舌部悬挂舌部;以及固定机构， 患者的下颌骨包括一个用于接合一个或多个缝合线的调节组件并调节缝线环上的张力。 还公开了可以与光泽悬挂系统一起使用的各种系绳和锚。
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2.发明申请METHODS AND DEVICES FOR THE TREATMENT OF AIRWAY OBSTRUCTION, SLEEP APNEA AND SNORING 有权用于治疗空气障碍，睡眠和睡眠的方法和装置公开(公告)号：US20080053461A1
公开(公告)日：2008-03-06
申请号：US11835966
申请日：2007-08-08
申请人： Mark Hirotsuka , Jasper Jackson , Damien Shulock , Andrew Frazier , Chad Roue , Erik van der Burg , Michael Dineen
发明人： Mark Hirotsuka , Jasper Jackson , Damien Shulock , Andrew Frazier , Chad Roue , Erik van der Burg , Michael Dineen
CPC分类号： A61F5/566 , A61B17/0401 , A61B17/0642 , A61B17/24 , A61B2017/00862 , A61B2017/00867 , A61B2017/044 , A61B2017/06176
摘要： Methods and devices for the treatment of airway obstruction, sleep apnea and snoring are disclosed. In some embodiments, a glossal suspension system includes a tissue tensioner that includes a suture loop made of one or more sutures configured to suspend the tongue with at least one portion configured to extend laterally through the tongue, and a securement mechanism configured to be attached to a patient's mandible that includes one more adjustment assemblies for engaging the one or more sutures and adjusting tension on the suture loop. Various tethers and anchors that can be used with the glossal suspension system are also disclosed.
摘要翻译： 公开了治疗气道阻塞，睡眠呼吸暂停和打鼾的方法和装置。 在一些实施例中，光泽悬挂系统包括组织张紧器，该组织张紧器包括由一个或多个缝合线构成的缝合线圈，所述缝合线圈被配置为使至少一部分被配置成横向延伸穿过舌部悬挂舌部;以及固定机构， 患者的下颌骨包括一个用于接合一个或多个缝合线的调节组件并调节缝线环上的张力。 还公开了可以与光泽悬挂系统一起使用的各种系绳和锚。
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公开(公告)号：US08757163B2
公开(公告)日：2014-06-24
申请号：US13350867
申请日：2012-01-16
申请人： Michael Dineen , Mark Hirotsuka , Jasper Jackson , Damien Shulock , Andrew Frazier , Chad Roue , Erik Van Der Burg
发明人： Michael Dineen , Mark Hirotsuka , Jasper Jackson , Damien Shulock , Andrew Frazier , Chad Roue , Erik Van Der Burg
CPC分类号： A61F5/566 , A61B17/0401 , A61B17/0487 , A61B17/06166 , A61B17/24 , A61B2017/00004 , A61B2017/00814 , A61B2017/00862 , A61B2017/00986 , A61B2017/0403 , A61B2017/0409 , A61B2017/0412 , A61B2017/0414 , A61B2017/0417 , A61B2017/042 , A61B2017/0422 , A61B2017/0427 , A61B2017/0433 , A61B2017/0435 , A61B2017/0437 , A61B2017/0438 , A61B2017/044 , A61B2017/0451 , A61B2017/0454 , A61B2017/0458 , A61B2017/0461 , A61B2017/0462 , A61B2017/0464 , A61B2017/0496 , A61B2017/06171 , A61B2017/06176 , A61B2017/0618 , A61B2017/248 , A61F5/56
摘要： Embodiments of the present invention relate to methods and devices for the treatment of airway obstruction, such as obstructive sleep apnea, and devices and methods that facilitate insertion and retrieval of the same. In one embodiment, disclosed is a tissue tensioner that includes an elongate flexible tether having a first end and a second end, a bone anchor configured to be connected to a patient's mandible, a tissue ingrowth implant configured to be implanted in a patient's tongue and connected to the second end of the tether, and an adjustment mechanism configured to be held by the bone anchor adjacent the patient's mandible and configured to receive the first end of the tether and configured to adjust tension in the flexible tether between the patient's mandible and tongue. Various anchors, tethers, securement mechanisms, and adjustment mechanisms that can be used with glossal and palatal remodeling systems are also disclosed.
摘要翻译： 本发明的实施例涉及用于治疗气道阻塞的方法和装置，例如阻塞性睡眠呼吸暂停，以及便于其插入和取回的装置和方法。 在一个实施例中，公开了一种组织张紧器，其包括具有第一端和第二端的细长柔性系绳，构造成连接到患者下颌骨的骨锚固件，构造成植入患者舌头并连接的组织向内植入物 到所述系绳的第二端，以及调整机构，其被构造成由所述骨锚固体邻近所述患者的下颌骨并被配置为接收所述系绳的所述第一端并且被配置为调节所述患者的下颌骨和舌头之间的柔性系绳中的张力。 还公开了可以与光泽和腭重建系统一起使用的各种锚，系绳，固定机构和调节机构。
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公开(公告)号：US08096303B2
公开(公告)日：2012-01-17
申请号：US11835931
申请日：2007-08-08
申请人： Michael Dineen , Mark Hirotsuka , Jasper Jackson , Damien Shulock , Andrew Frazier , Chad Roue , Erik van der Burg
发明人： Michael Dineen , Mark Hirotsuka , Jasper Jackson , Damien Shulock , Andrew Frazier , Chad Roue , Erik van der Burg
CPC分类号： A61F5/566 , A61B17/0401 , A61B17/0487 , A61B17/06166 , A61B17/24 , A61B2017/00004 , A61B2017/00814 , A61B2017/00862 , A61B2017/00986 , A61B2017/0403 , A61B2017/0409 , A61B2017/0412 , A61B2017/0414 , A61B2017/0417 , A61B2017/042 , A61B2017/0422 , A61B2017/0427 , A61B2017/0433 , A61B2017/0435 , A61B2017/0437 , A61B2017/0438 , A61B2017/044 , A61B2017/0451 , A61B2017/0454 , A61B2017/0458 , A61B2017/0461 , A61B2017/0462 , A61B2017/0464 , A61B2017/0496 , A61B2017/06171 , A61B2017/06176 , A61B2017/0618 , A61B2017/248 , A61F5/56
摘要： Embodiments of the present invention relate to methods and devices for the treatment of airway obstruction, such as obstructive sleep apnea, and devices and methods that facilitate insertion and retrieval of the same. In one embodiment, disclosed is a tissue tensioner that includes an elongate flexible tether having a first end and a second end, a bone anchor configured to be connected to a patient's mandible, a tissue ingrowth implant configured to be implanted in a patient's tongue and connected to the second end of the tether, and an adjustment mechanism configured to be held by the bone anchor adjacent the patient's mandible and configured to receive the first end of the tether and configured to adjust tension in the flexible tether between the patient's mandible and tongue. Various anchors, tethers, securement mechanisms, and adjustment mechanisms that can be used with glossal and palatal remodeling systems are also disclosed.
摘要翻译： 本发明的实施例涉及用于治疗气道阻塞的方法和装置，例如阻塞性睡眠呼吸暂停，以及便于其插入和取回的装置和方法。 在一个实施例中，公开了一种组织张紧器，其包括具有第一端和第二端的细长柔性系绳，构造成连接到患者下颌骨的骨锚固件，构造成植入患者舌头并连接的组织向内植入物 到所述系绳的第二端，以及调整机构，其被构造成由所述骨锚固体邻近所述患者的下颌骨并被配置为接收所述系绳的所述第一端并且被配置为调节所述患者的下颌骨和舌头之间的柔性系绳中的张力。 还公开了可以与光泽和腭重建系统一起使用的各种锚，系绳，固定机构和调节机构。
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5.发明申请公开(公告)号：US20080066769A1
公开(公告)日：2008-03-20
申请号：US11835931
申请日：2007-08-08
申请人： Michael Dineen , Mark Hirotsuka , Jasper Jackson , Damien Shulock , Andrew Frazier , Chad Roue , Erik van der Burg
发明人： Michael Dineen , Mark Hirotsuka , Jasper Jackson , Damien Shulock , Andrew Frazier , Chad Roue , Erik van der Burg
IPC分类号： A61B19/00
CPC分类号： A61F5/566 , A61B17/0401 , A61B17/0487 , A61B17/06166 , A61B17/24 , A61B2017/00004 , A61B2017/00814 , A61B2017/00862 , A61B2017/00986 , A61B2017/0403 , A61B2017/0409 , A61B2017/0412 , A61B2017/0414 , A61B2017/0417 , A61B2017/042 , A61B2017/0422 , A61B2017/0427 , A61B2017/0433 , A61B2017/0435 , A61B2017/0437 , A61B2017/0438 , A61B2017/044 , A61B2017/0451 , A61B2017/0454 , A61B2017/0458 , A61B2017/0461 , A61B2017/0462 , A61B2017/0464 , A61B2017/0496 , A61B2017/06171 , A61B2017/06176 , A61B2017/0618 , A61B2017/248 , A61F5/56
摘要： Embodiments of the present invention relate to methods and devices for the treatment of airway obstruction, such as obstructive sleep apnea, and devices and methods that facilitate insertion and retrieval of the same. In one embodiment, disclosed is a tissue tensioner that includes an elongate flexible tether having a first end and a second end, a bone anchor configured to be connected to a patient's mandible, a tissue ingrowth implant configured to be implanted in a patient's tongue and connected to the second end of the tether, and an adjustment mechanism configured to be held by the bone anchor adjacent the patient's mandible and configured to receive the first end of the tether and configured to adjust tension in the flexible tether between the patient's mandible and tongue. Various anchors, tethers, securement mechanisms, and adjustment mechanisms that can be used with glossal and palatal remodeling systems are also disclosed.
摘要翻译： 本发明的实施例涉及用于治疗气道阻塞的方法和装置，例如阻塞性睡眠呼吸暂停，以及便于其插入和取回的装置和方法。 在一个实施例中，公开了一种组织张紧器，其包括具有第一端和第二端的细长柔性系绳，构造成连接到患者下颌骨的骨锚固件，构造成植入患者舌头并连接的组织向内植入物 到所述系绳的第二端，以及调整机构，其被构造成由所述骨锚固体邻近所述患者的下颌骨并被配置为接收所述系绳的所述第一端并且被配置为调节所述患者的下颌骨和舌头之间的柔性系绳中的张力。 还公开了可以与光泽和腭重建系统一起使用的各种锚，系绳，固定机构和调节机构。
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公开(公告)号：US20080027560A1
公开(公告)日：2008-01-31
申请号：US11762652
申请日：2007-06-13
申请人： Jasper Jackson , Andrew Frazier , Chad Roue , Erik van der Burg , Michael Dineen , Mark Hirotsuka
发明人： Jasper Jackson , Andrew Frazier , Chad Roue , Erik van der Burg , Michael Dineen , Mark Hirotsuka
IPC分类号： A61F2/02
CPC分类号： A61B17/0401 , A61B17/24 , A61B2017/00814 , A61B2017/0412 , A61B2017/042 , A61B2017/0422 , A61B2017/0427 , A61B2017/0433 , A61B2017/0435 , A61B2017/0437 , A61B2017/0438 , A61B2017/044 , A61B2017/0443 , A61B2017/045 , A61B2017/0451 , A61B2017/0453 , A61B2017/0458 , A61B2017/0461 , A61B2017/0462 , A61B2017/0464 , A61B2017/0496 , A61B2017/06057 , A61B2017/0618 , A61B2017/248 , A61B2018/00327 , A61F5/566
摘要： Methods and devices are disclosed for manipulating the tongue. An implant is positioned within at least a portion of the tongue and may be secured to other surrounding structures such as the mandible and/or hyoid bone. In general, the implant is manipulated to displace at least a portion of the posterior tongue in an anterior or lateral direction, or to alter the tissue tension or compliance of the tongue. Methods and devices for engaging the tongue are also disclosed. One embodiment of a tongue remodeling system includes an elongate implant configured to be positioned within a selected region of the tongue and a tether configured to suspend the tongue. The tether can be configured to be looped around the elongate implant and connected to another structure.
摘要翻译： 公开了用于操纵舌头的方法和装置。 植入物定位在舌头的至少一部分内，并且可以固定到其他周围结构，例如下颌骨和/或舌骨。 通常，植入物被操纵以在前侧或后侧方向上移位后舌的至少一部分，或改变组织张力或舌的顺应性。 还公开了用于接合舌头的方法和装置。 舌重建系统的一个实施例包括被配置为定位在舌的选定区域内的细长植入物和构造成悬挂舌头的系绳。 系绳可被配置为环绕细长植入物并且连接到另一结构。
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公开(公告)号：US09408742B2
公开(公告)日：2016-08-09
申请号：US11762642
申请日：2007-06-13
申请人： Michael Dineen , Mark Hirotsuka , Jasper Jackson , Andrew Frazier , Chad Roue , Erik van der Burg
发明人： Michael Dineen , Mark Hirotsuka , Jasper Jackson , Andrew Frazier , Chad Roue , Erik van der Burg
CPC分类号： A61B17/0401 , A61B17/24 , A61B2017/0412 , A61B2017/042 , A61B2017/0422 , A61B2017/0427 , A61B2017/0433 , A61B2017/0435 , A61B2017/0437 , A61B2017/0438 , A61B2017/044 , A61B2017/0443 , A61B2017/0445 , A61B2017/045 , A61B2017/0451 , A61B2017/0453 , A61B2017/0458 , A61B2017/0461 , A61B2017/0462 , A61B2017/0464 , A61B2017/0496 , A61B2017/06057 , A61B2017/0618 , A61B2017/248 , A61F5/566
摘要： Methods and devices are disclosed for manipulating the tongue. An implant is positioned within at least a portion of the tongue and may be secured to other surrounding structures such as the mandible and/or hyoid bone. In general, the implant is manipulated to displace at least a portion of the posterior tongue in an anterior or lateral direction, or to alter the tissue tension or compliance of the tongue. Methods and devices for adjusting a glossopexy system are also disclosed. Adjusting a distance between two body-engaging structures can be performed without disengaging a tether from either of the body-engaging structures in some embodiments.
摘要翻译： 公开了用于操纵舌头的方法和装置。 植入物定位在舌头的至少一部分内，并且可以固定到其他周围结构，例如下颌骨和/或舌骨。 通常，植入物被操纵以在前侧或后侧方向上移位后舌的至少一部分，或改变组织张力或舌的顺应性。 还公开了用于调节glossopexy系统的方法和装置。 在一些实施例中，可以在不脱离任何身体接合结构的系绳的情况下执行调节两个身体接合结构之间的距离。
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8.发明授权Glassoplasty using tissue anchor glossopexy with volumetric tongue reduction 有权玻璃体成形术使用组织锚glossopexy与体积舌头减少公开(公告)号：US09393067B2
公开(公告)日：2016-07-19
申请号：US13461894
申请日：2012-05-02
申请人： Erik van der Burg , Beverly Tucker Woodson , Michael Dineen , Mark Hirotsuka , Jasper Jackson , Andrew Frazier , Chad Roue
发明人： Erik van der Burg , Beverly Tucker Woodson , Michael Dineen , Mark Hirotsuka , Jasper Jackson , Andrew Frazier , Chad Roue
CPC分类号： A61B18/1477 , A61B17/0401 , A61B17/0487 , A61B2017/00814 , A61B2017/0412 , A61B2017/0422 , A61B2017/0427 , A61B2017/0451 , A61B2017/0454 , A61B2017/0461 , A61B2017/0462 , A61B2017/0464 , A61B2017/0496 , A61B2017/06176 , A61B2017/248 , A61B2018/00279 , A61B2018/00327
摘要： Methods and devices are disclosed for remodeling the tongue. One or more spaces or cavities are formed in the tongue using, for example, surgical or RF ablative techniques. The cavities can be closed or collapsed by inserting a tethered soft tissue anchor into the tongue and attaching the tethered portion of the soft tissue anchor to a bony structure such as the mandible or hyoid bone in order to exert a collapsing force on the one or more spaces or cavities. The insertion pathway of the tethered soft tissue anchor may pass adjacent to or even through one or more cavities. Also disclosed herein is a tongue remodeling system that includes means for creating a space in the tongue, and a tissue anchor configured to close the space. The tissue anchor may be tethered or expandable.
摘要翻译： 公开了用于重塑舌头的方法和装置。 使用例如手术或RF烧蚀技术在舌部中形成一个或多个空间或空腔。 通过将系留的软组织锚固件插入舌部并将软组织锚固件的系留部分附接到诸如下颌骨或舌骨的骨结构以便在一个或多个上施加塌陷力，可以将空腔封闭或折叠 空间或空腔 系留软组织锚的插入路径可以邻近或甚至通过一个或多个空腔。 本文还公开了一种舌头重塑系统，其包括用于在舌头中产生空间的装置和构造成关闭空间的组织锚。 组织锚可以是束缚的或可膨胀的。
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9.发明授权Glossoplasty using tissue anchor glossopexy with volumetric tongue reduction 有权使用组织锚glossopexy与舌体缩小的Glossoplasty公开(公告)号：US08186355B2
公开(公告)日：2012-05-29
申请号：US11598220
申请日：2006-11-09
申请人： Erik van der Burg , Beverly Tucker Woodson , Michael Dineen , Mark Hirotsuka , Jasper Jackson , Andrew Frazier , Chad Roue
发明人： Erik van der Burg , Beverly Tucker Woodson , Michael Dineen , Mark Hirotsuka , Jasper Jackson , Andrew Frazier , Chad Roue
CPC分类号： A61B18/1477 , A61B17/0401 , A61B17/0487 , A61B2017/00814 , A61B2017/0412 , A61B2017/0422 , A61B2017/0427 , A61B2017/0451 , A61B2017/0454 , A61B2017/0461 , A61B2017/0462 , A61B2017/0464 , A61B2017/0496 , A61B2017/06176 , A61B2017/248 , A61B2018/00279 , A61B2018/00327
摘要： Methods and devices are disclosed for remodeling the tongue. One or more spaces or cavities are formed in the tongue using, for example, surgical or RF ablative techniques. The cavities can be closed or collapsed by inserting a tethered soft tissue anchor into the tongue and attaching the tethered portion of the soft tissue anchor to a bony structure such as the mandible or hyoid bone in order to exert a collapsing force on the one or more spaces or cavities. The insertion pathway of the tethered soft tissue anchor may pass adjacent to or even through one or more cavities. Also disclosed herein is a tongue remodeling system that includes means for creating a space in the tongue, and a tissue anchor configured to close the space. The tissue anchor may be tethered or expandable.
摘要翻译： 公开了用于重塑舌头的方法和装置。 使用例如手术或RF烧蚀技术在舌部中形成一个或多个空间或空腔。 通过将系留的软组织锚固件插入舌部并将软组织锚固件的系留部分附接到诸如下颌骨或舌骨的骨结构以便在一个或多个上施加塌陷力，可以将空腔封闭或折叠 空间或空腔 系留软组织锚的插入路径可以邻近或甚至通过一个或多个空腔。 本文还公开了一种舌头重塑系统，其包括用于在舌头中产生空间的装置和构造成关闭空间的组织锚。 组织锚可以是束缚的或可膨胀的。
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10.发明授权公开(公告)号：US08038712B2
公开(公告)日：2011-10-18
申请号：US11770471
申请日：2007-06-28
申请人： Erik van der Burg , Michael Dineen , Mark Hirotsuka , Jasper Jackson , Andrew Frazier , Chad Roue
发明人： Erik van der Burg , Michael Dineen , Mark Hirotsuka , Jasper Jackson , Andrew Frazier , Chad Roue
CPC分类号： A61F5/08 , A61B17/0401 , A61B17/0469 , A61B17/24 , A61B2017/00792 , A61B2017/06052 , A61B2017/06176 , A61F2/186 , A61F2002/2885
摘要： Methods and devices for rhinoplasty and treating nasal valve stenosis are disclosed herein. The nasal valve acts as a flow-limiter and can contribute to airway obstruction if resistance within the nasal valve is excessive. In one embodiment, a system for treating nasal valve stenosis includes a first elongate implant and a second elongate implant configured to support the nasal valves when implanted. The implants can be coupled together by connecting elements, such as eyelets, tethers, complementary socket joints, and button-rivet supports.
摘要翻译： 本文公开了用于鼻整形术和治疗鼻瓣狭窄的方法和装置。 鼻阀作为流量限制器，如果鼻阀内的阻力过大，可能有助于气道阻塞。 在一个实施例中，一种用于治疗鼻瓣狭窄的系统包括第一细长植入物和构造成在植入时支撑鼻塞阀的第二细长植入物。 植入物可以通过连接元件（例如孔眼，系绳，互补的插座接头和按钮铆钉支撑件）联接在一起。
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