公开(公告)号：US06436138B1

公开(公告)日：2002-08-20

申请号：US09155064

申请日：1998-09-18

申请人： Michael Dowd ,  Nelson L. Scarborough ,  Mark Daugherty ,  Jack McMickle

发明人： Michael Dowd ,  Nelson L. Scarborough ,  Mark Daugherty ,  Jack McMickle

IPC分类号： A61F228

CPC分类号： A61L27/3691 ,  A61F2/28 ,  A61F2/3094 ,  A61F2/4644 ,  A61F2002/30957 ,  A61F2002/4649 ,  A61L27/3608 ,  A61L27/365 ,  A61L27/3683 ,  A61L27/3687 ,  A61L2430/40 ,  Y10S623/901 ,  Y10S623/919

摘要： A process for fabricating shaped material from demineralized bone particles includes the steps of applying a liquid slurry of demineralized bone particles to a support, removing excess liquid form the demineralized bone particles to provide a cohering shaped mass of demineralized bone particles, and warming the shaped mass of demineralized bone particles at a predetermined temperature and for a predetermined time period. The resultant bone mass exhibits enhanced tensile strength and minimal bone particle disassociation upon rehydration thereby improving product handling and application at the operative site.

摘要翻译： 从软化骨粒子制造成形材料的方法包括以下步骤：将软化骨颗粒的液体浆料施加到支撑体上，从脱矿骨粒子中除去多余的液体，以提供凝固成型的脱矿质骨粒子，并加热成形质量 的软化骨颗粒在预定温度和预定时间段内。 所得骨量在再水化时表现出增强的拉伸强度和最小的骨粒子分离，从而改善在手术部位的产品处理和应用。

公开(公告)号：US5607269A

公开(公告)日：1997-03-04

申请号：US560213

申请日：1995-11-21

申请人： Michael Dowd ,  Nelson Scarborough ,  Mark Daugherty

发明人： Michael Dowd ,  Nelson Scarborough ,  Mark Daugherty

IPC分类号： B23Q11/08

CPC分类号： A61F2/4644 ,  B23Q11/0825 ,  A61F2002/4645 ,  Y10S29/056 ,  Y10S29/06 ,  Y10S29/086 ,  Y10T409/30392

摘要： A milling apparatus is disclosed which includes a milling machine having a milling cutter which is sealingly isolated from the milling machine within an enclosed work area, a support fixture disposed within the enclosed work area for supporting a work piece, and a mechanism for moving the milling cutter along a predetermined path relative to the work piece. Preferably, the milling apparatus is employed to cut bone into small fragments for subsequent utilization, and the sealed isolation of the milling cutter inhibits cross-contamination between differing work pieces.

摘要翻译： 公开了一种铣削装置，其包括具有铣削刀具的铣床，所述铣刀在封闭的工作区域内与铣床密封地隔离，设置在封闭的工作区域内用于支撑工件的支撑夹具以及用于移动铣削 切割器沿相对于工件的预定路径。 优选地，铣削装置用于将骨切割成小碎片以供后续利用，并且铣刀的密封隔离抑制不同工件之间的交叉污染。

公开(公告)号：US06530955B2

公开(公告)日：2003-03-11

申请号：US09861369

申请日：2001-05-18

申请人： John W. Boyle ,  Lawrence A. Shimp ,  David R. Kaes ,  John W. Morris ,  Erik O. Martz ,  Todd M. Boyce ,  Mark Daugherty

发明人： John W. Boyle ,  Lawrence A. Shimp ,  David R. Kaes ,  John W. Morris ,  Erik O. Martz ,  Todd M. Boyce ,  Mark Daugherty

IPC分类号： A61F244

CPC分类号： A61F2/4611 ,  A61F2/28 ,  A61F2/30771 ,  A61F2/30965 ,  A61F2/442 ,  A61F2/4465 ,  A61F2/447 ,  A61F2002/2817 ,  A61F2002/2825 ,  A61F2002/2835 ,  A61F2002/30112 ,  A61F2002/30115 ,  A61F2002/30131 ,  A61F2002/30153 ,  A61F2002/30158 ,  A61F2002/3023 ,  A61F2002/30235 ,  A61F2002/30238 ,  A61F2002/30266 ,  A61F2002/3028 ,  A61F2002/30324 ,  A61F2002/30772 ,  A61F2002/30774 ,  A61F2002/30785 ,  A61F2002/30789 ,  A61F2002/3082 ,  A61F2002/30836 ,  A61F2002/30843 ,  A61F2002/30904 ,  A61F2002/30952 ,  A61F2002/4623 ,  A61F2002/4627 ,  A61F2002/4649 ,  A61F2230/0004 ,  A61F2230/0006 ,  A61F2230/0013 ,  A61F2230/0019 ,  A61F2230/0026 ,  A61F2230/0063 ,  A61F2230/0069 ,  A61F2230/0082 ,  A61F2250/0036 ,  A61F2310/00017 ,  A61F2310/00023 ,  A61F2310/00131 ,  A61F2310/00293 ,  A61F2310/00359

摘要： A ramp-shaped intervertebral implant is disclosed. The implant has a body having a first end, a second end, a top surface and a bottom surface. At least one of the top and bottom surfaces is tapered and converges towards the second end of the body. An opening extends through the body and has one end opening onto the top surface of the implant and the other end opening onto the bottom surface of the implant. The implant can be formed from the diaphysis or metaphysis of a long bone, wherein the intramedullary canal of the long bone defines the opening. Alternately, the implant can be made from any biocompatible material having the requisite strength requirement.

公开(公告)号：US06277149B1

公开(公告)日：2001-08-21

申请号：US09328242

申请日：1999-06-08

申请人： John W. Boyle ,  Lawrence A. Shimp ,  David R. Kaes ,  John W. Morris ,  Erik O. Martz ,  Todd M. Boyce ,  Mark Daugherty

发明人： John W. Boyle ,  Lawrence A. Shimp ,  David R. Kaes ,  John W. Morris ,  Erik O. Martz ,  Todd M. Boyce ,  Mark Daugherty

IPC分类号： A61F244

CPC分类号： A61F2/4611 ,  A61F2/28 ,  A61F2/30771 ,  A61F2/30965 ,  A61F2/442 ,  A61F2/4465 ,  A61F2/447 ,  A61F2002/2817 ,  A61F2002/2825 ,  A61F2002/2835 ,  A61F2002/30112 ,  A61F2002/30115 ,  A61F2002/30131 ,  A61F2002/30153 ,  A61F2002/30158 ,  A61F2002/3023 ,  A61F2002/30235 ,  A61F2002/30238 ,  A61F2002/30266 ,  A61F2002/3028 ,  A61F2002/30324 ,  A61F2002/30772 ,  A61F2002/30774 ,  A61F2002/30785 ,  A61F2002/30789 ,  A61F2002/3082 ,  A61F2002/30836 ,  A61F2002/30843 ,  A61F2002/30904 ,  A61F2002/30952 ,  A61F2002/4623 ,  A61F2002/4627 ,  A61F2002/4649 ,  A61F2230/0004 ,  A61F2230/0006 ,  A61F2230/0013 ,  A61F2230/0019 ,  A61F2230/0026 ,  A61F2230/0063 ,  A61F2230/0069 ,  A61F2230/0082 ,  A61F2250/0036 ,  A61F2310/00017 ,  A61F2310/00023 ,  A61F2310/00131 ,  A61F2310/00293 ,  A61F2310/00359

摘要： A ramp-shaped intervertebral implant is disclosed. The implant has a body having a first end, a second end, a top surface and a bottom surface. At least one of the top and bottom surfaces is tapered and converges towards the second end of the body. An opening extends through the body and has one end opening onto the top surface of the implant and the other end opening onto the bottom surface of the implant. The implant can be formed from the diaphysis or metaphysis of a long bone, wherein the intramedullary canal of the long bone defines the opening. Alternately, the implant can be made from any biocompatible material having the requisite strength requirement.

摘要翻译： 公开了一种斜坡状椎间植入物。 植入物具有具有第一端，第二端，顶表面和底表面的主体。 顶表面和底表面中的至少一个是锥形的并且朝向身体的第二端会聚。 开口延伸穿过主体并且在植入物的顶表面上具有一个端部开口，并且另一端开口延伸到植入物的底表面上。 植入物可以由长骨的骨干或干be形成，其中长骨的髓内管限定开口。 或者，植入物可以由具有必要强度要求的任何生物相容性材料制成。

公开(公告)号：US20060024656A1

公开(公告)日：2006-02-02

申请号：US10509585

申请日：2003-03-31

申请人： John Morris ,  Kenneth Petersen ,  Lawrence Shimp ,  Mark Daugherty

发明人： John Morris ,  Kenneth Petersen ,  Lawrence Shimp ,  Mark Daugherty

IPC分类号： A01N1/00 ,  C12N5/08

CPC分类号： A61L27/3683 ,  A01N1/00 ,  A61F2/4644 ,  A61F2002/2835 ,  A61F2002/4645 ,  A61F2002/4649 ,  A61F2310/00365 ,  A61L27/3608 ,  A61L27/365 ,  A61L2430/02 ,  A61L2430/40

摘要： The present invention relates to a method for making bone particles from bone of a variety of sizes and a workpiece forming and holding device for use with the method. The workpiece forming device includes a base and a base frame attached to the surface of the base. An apparatus for forming a solidified mass of bone and immobilization medium is also provided which includes the workpiece forming device and a detachable former member enclosing the base frame. Bone is immersed in an immobilization medium within such workpiece forming device, which is solidified to form a solidified mass of bone and immobilization medium and then subdivided to provide particles of bone in association to with immobilization medium. The immobilization medium may be optionally removed to leave bone particles suitable for use in orthopedic applications including implants.

摘要翻译： 本发明涉及一种用于制造各种尺寸的骨的骨颗粒的方法和用于该方法的工件形成和保持装置。 工件形成装置包括基部和附接到基部的表面的基部框架。 还提供了一种用于形成固化骨和固定介质的装置，其包括工件形成装置和包围基架的可拆卸的成形构件。 将骨浸入这种工件形成装置内的固定介质中，固化介质被固化以形成骨和固定介质的固化块，然后细分以提供与固定介质相关联的骨颗粒。 可以任选地除去固定介质以留下适合用于矫形应用的骨颗粒，包括植入物。