公开(公告)号：US20130044200A1

公开(公告)日：2013-02-21

申请号：US13211875

申请日：2011-08-17

申请人： Michael H. Brill ,  Hong Wei ,  Taeyoung Park

发明人： Michael H. Brill ,  Hong Wei ,  Taeyoung Park

IPC分类号： H04N7/18 ,  G06K9/00

CPC分类号： G02B21/365

摘要： A system and apparatus for the color calibration of images recorded through a microscope. An integrated color calibration target microscope slide device and specimen are recorded with an imaging device that acquires both the color values of the specimen and the color values of the color calibration target under a plurality of illuminations and trans-illuminations. A composite image is formed to provide a spectral estimation of the relevant color values of the image. The image is converted into multi-stimulus values governed by a plurality of illuminating conditions. The multi-stimulus values are used to provide image calibration data so that color values of the image, when displayed on a display devices, are faithfully reproduced.

摘要翻译： 用于通过显微镜记录的图像的颜色校准的系统和装置。 使用在多个照明和反照照下获取样本的颜色值和颜色校准目标的颜色值的成像装置来记录集成的颜色校准目标显微镜载玻片装置和样本。 形成合成图像以提供图像的相关颜色值的谱估计。 图像被转换为​​由多个照明条件控制的多刺激值。 多刺激值用于提供图像校准数据，使得当显示在显示装置上时，图像的颜色值被忠实地再现。

公开(公告)号：US08976239B2

公开(公告)日：2015-03-10

申请号：US13594107

申请日：2012-08-24

申请人： Hong Wei ,  Michael H. Brill

发明人： Hong Wei ,  Michael H. Brill

IPC分类号： H04N7/18

CPC分类号： G02B21/34 ,  G01J3/465 ,  G01J3/513 ,  G01J3/52 ,  G01J3/522 ,  G01J3/524 ,  G02B21/0064 ,  G02B21/365

摘要： The present invention concerns a system and method for calibration and adjustment of the pixel color values represented within a digital image of a sample by a transmission microscope. Furthermore the present invention is directed to providing sufficient color information in order to generate a color mapping matrix that allows for the creation of a synthetic image to depict the sample under a desired illumination. The system and method provides a solution that generates a destination-device independent image that is configurable to any calibrated display device.

摘要翻译： 本发明涉及通过透射显微镜校准和调整在样品的数字图像内表示的像素颜色值的系统和方法。 此外，本发明旨在提供足够的颜色信息，以便产生颜色映射矩阵，其允许创建合成图像以在期望的照明下描绘样本。 该系统和方法提供了一种解决方案，其生成可配置为任何校准显示设备的目标设备独立映像。

公开(公告)号：US20140055592A1

公开(公告)日：2014-02-27

申请号：US13594107

申请日：2012-08-24

申请人： Hong Wei ,  Michael H. Brill

发明人： Hong Wei ,  Michael H. Brill

IPC分类号： H04N7/18

CPC分类号： G02B21/34 ,  G01J3/465 ,  G01J3/513 ,  G01J3/52 ,  G01J3/522 ,  G01J3/524 ,  G02B21/0064 ,  G02B21/365

摘要： The present invention concerns a system and method for calibration and adjustment of the pixel color values represented within a digital image of a sample by a transmission microscope. Furthermore the present invention is directed to providing sufficient color information in order to generate a color mapping matrix that allows for the creation of a synthetic image to depict the sample under a desired illumination. The system and method provides a solution that generates a destination-device independent image that is configurable to any calibrated display device.

摘要翻译： 本发明涉及通过透射显微镜校准和调整在样品的数字图像内表示的像素颜色值的系统和方法。 此外，本发明旨在提供足够的颜色信息，以便产生颜色映射矩阵，其允许创建合成图像以在期望的照明下描绘样本。 该系统和方法提供了一种解决方案，其生成可配置为任何校准显示设备的目标设备独立映像。

公开(公告)号：US20090141042A1

公开(公告)日：2009-06-04

申请号：US12323432

申请日：2008-11-25

申请人： Colman Shannon ,  Cormic K. Merle ,  Michael H. Brill ,  Brian Levey

发明人： Colman Shannon ,  Cormic K. Merle ,  Michael H. Brill ,  Brian Levey

IPC分类号： G09G5/02

CPC分类号： G09G3/006 ,  G01J3/465 ,  G01J3/506 ,  G01J3/51 ,  G01J3/513 ,  G01J3/524 ,  G09G5/026 ,  G09G2320/0666

摘要： One embodiment of a method for calibrating a test color measurement device in conjunction with an emissive display includes measuring initial spectral sensitivities of at least four channels of the test color measurement device, linearly regressing the spectral sensitivities to a least-square best fit to CIE color matching functions, measuring CIE tristimulus values of test colors on the display using a reference color measurement device, measuring the CIE tristimulus values on the display using the test color measurement device, transforming the CIE tristimulus values measured by the test color measurement device to CIE tristimulus values that would have been measured by the reference color measurement device, using a nonlinear function with variable fitting coefficients, and storing initial fitting coefficient values that provide a least-square best fit of the CIE tristimulus values measured by the test color measurement device and the CIE tristimulus values measured by the reference color measurement device.

摘要翻译： 用于校准与发射显示器的测试颜色测量装置的方法的一个实施例包括测量测试颜色测量装置的至少四个通道的初始光谱灵敏度，将光谱灵敏度线性回归到CIE颜色的最小二乘最佳拟合 使用参考颜色测量装置测量显示器上的测试颜色的CIE三刺激值，使用测试颜色测量装置测量显示器上的CIE三刺激值，将由测试颜色测量装置测量的CIE三刺激值转换为CIE三刺激 使用具有可变拟合系数的非线性函数，以及存储提供由测试颜色测量装置测量的CIE三刺激值的最小二乘最佳拟合的初始拟合系数值的参考颜色测量装置将测量的值，以及 CIE三刺激值由参考值测量 色彩测量装置。

公开(公告)号：US09200963B2

公开(公告)日：2015-12-01

申请号：US13585346

申请日：2012-08-14

申请人： Zhiling Xu ,  Michael H. Brill

发明人： Zhiling Xu ,  Michael H. Brill

IPC分类号： G01J3/52

CPC分类号： G01J3/524

摘要： One embodiment of a method for aligning measurements taken by a plurality of color measurement instruments with measurements taken by an industry standard color measurement instrument includes receiving a first set of spectral data from the plurality of instruments, receiving a second set of spectral data from the industry standard instrument, generating initial profiles for the plurality of instruments (by producing, for each given instrument, a first correction that aligns the spectral data taken by the given instrument with the second set of spectral data), mathematically correcting the first set of spectral data using the initial profiles to produce a third set of spectral data, and generating new profiles for the plurality of instruments (by calculating a mean of the third set of spectral data, and producing, for each given instrument, a second correction that aligns the spectral data taken by the given instrument with the mean.

摘要翻译： 用于将由多个颜色测量仪器进行的测量与由工业标准颜色测量仪器进行的测量对准的方法对准的方法的一个实施例包括从多个仪器接收第一组光谱数据，从该行业接收第二组光谱数据 生成多个仪器的初始轮廓（通过为每个给定的仪器产生将给定仪器取得的光谱数据与第二组光谱数据对齐的第一校正），在数学上校正第一组光谱数据 使用初始轮廓来产生第三组频谱数据，并且生成用于多个乐器的新轮廓（通过计算第三组频谱数据的平均值，并为每个给定乐器产生对准频谱的第二校正 给定仪器用平均值采集的数据。

公开(公告)号：US20140019079A1

公开(公告)日：2014-01-16

申请号：US13585346

申请日：2012-08-14

申请人： Zhiling Xu ,  Michael H. Brill

发明人： Zhiling Xu ,  Michael H. Brill

IPC分类号： G01J3/46

CPC分类号： G01J3/524

摘要： One embodiment of a method for aligning measurements taken by a plurality of color measurement instruments with measurements taken by an industry standard color measurement instrument includes receiving a first set of spectral data from the plurality of instruments, receiving a second set of spectral data from the industry standard instrument, generating initial profiles for the plurality of instruments (by producing, for each given instrument, a first correction that aligns the spectral data taken by the given instrument with the second set of spectral data), mathematically correcting the first set of spectral data using the initial profiles to produce a third set of spectral data, and generating new profiles for the plurality of instruments (by calculating a mean of the third set of spectral data, and producing, for each given instrument, a second correction that aligns the spectral data taken by the given instrument with the mean.

摘要翻译： 用于将由多个颜色测量仪器进行的测量与由工业标准颜色测量仪器进行的测量对准的方法对准的方法的一个实施例包括从多个仪器接收第一组光谱数据，从该行业接收第二组光谱数据 生成多个仪器的初始轮廓（通过为每个给定的仪器产生将给定仪器取得的光谱数据与第二组光谱数据对齐的第一校正），在数学上校正第一组光谱数据 使用初始轮廓来产生第三组频谱数据，并且生成用于多个乐器的新轮廓（通过计算第三组频谱数据的平均值，并为每个给定乐器产生对准频谱的第二校正 给定仪器用平均值采集的数据。

公开(公告)号：US20120082374A1

公开(公告)日：2012-04-05

申请号：US12897583

申请日：2010-10-04

申请人： Niraj AGARWAL ,  Michael H. Brill

发明人： Niraj AGARWAL ,  Michael H. Brill

IPC分类号： G06K9/00

CPC分类号： H04N1/6033 ,  H04N1/6088

摘要： A method for evaluating a color of a sample includes acquiring an image having a plurality of pixels from a sample and a plurality of pixels from known color calibration patches. The image is color calibrated using the known color patches to endow the pixels from the sample with the tristimulus values they would have under one or more known illuminants. The calibrated image is transmitted, together with metadata, to a remote location where further computations and an approval process are performed. The further computations include comparing all of the pixels in the image of a standard that are of a first color to all pixels of a second color in the similarly calibrated image of the sample, where the second color is a color in the image of the sample that is most similar to the first color from the image of the standard.

摘要翻译： 用于评估样本的颜色的方法包括从已知颜色校准块的样本和多个像素获取具有多个像素的图像。 图像使用已知的色标进行颜色校准，以使来自样品的像素具有它们在一种或多种已知光源下具有的三刺激值。 经校准的图像与元数据一起发送到进行进一步计算和批准处理的远程位置。 进一步的计算包括在样本的类似校准图像中比较第一颜色的标准图像中的所有像素与第二颜色的所有像素，其中第二颜色是样本图像中的颜色 这与标准图像中的第一种颜色最相似。

公开(公告)号：US07230707B2

公开(公告)日：2007-06-12

申请号：US11016033

申请日：2004-12-17

申请人： Alan Ingleson ,  David Slocum ,  Michael H. Brill

发明人： Alan Ingleson ,  David Slocum ,  Michael H. Brill

IPC分类号： G01J3/46

CPC分类号： G01N21/255 ,  G01J3/0251 ,  G01J3/0262 ,  G01J3/0264 ,  G01J3/50 ,  G01N21/274 ,  G01N21/57 ,  G01N2201/0642 ,  G01N2201/065 ,  G06T7/90

摘要： Systems, methodologies, media, and other embodiments associated with color measuring are described. One exemplary system embodiment includes a spectrophotometer, one or more light sources for illuminating an interior of the spectrophotometer, and a digital camera configured at a port of the spectrophotometer and being configured to measure light components from a sample. In the present invention, segmentation logic is provided for the spectrophotometer that is configured to employ computational image segmentation to characterize specular reflection from a sample and to characterize a selected patch or portion from the test sample, such as a selected color in a multicolor pattern. In accordance with the present invention, the spectrophotometer and the included digital camera may be color-characterized in situ.

摘要翻译： 描述了与颜色测量相关联的系统，方法，介质和其它实施例。 一个示例性系统实施例包括分光光度计，用于照亮分光光度计内部的一个或多个光源，以及配置在分光光度计的端口处并被配置为测量来自样品的光分量的数字照相机。 在本发明中，为分光光度计提供分割逻辑，其被配置为采用计算图像分割来表征来自样本的镜面反射并且从所述测试样品（例如多色图案中的所选颜色）表征所选择的贴片或部分。 根据本发明，分光光度计和所附的数码相机可以原位进行颜色表征。

公开(公告)号：US06563936B2

公开(公告)日：2003-05-13

申请号：US09803392

申请日：2001-03-09

申请人： Michael H. Brill ,  Michael A. Isnardi ,  Albert P. Pica

发明人： Michael H. Brill ,  Michael A. Isnardi ,  Albert P. Pica

IPC分类号： H04K100

CPC分类号： G06T1/0071 ,  G06T1/0085 ,  G06T2201/0081 ,  G06T2201/0083 ,  H04N19/186 ,  H04N19/467 ,  H04N19/577 ,  H04N21/23892 ,  H04N21/8358

摘要： A channel is inserted into a sequence of frames for an image, by varying one or more display characteristics across a display in accordance with a spatio-temporal pattern applied to, for example, successive lines of each modified frame. The channel may be employed to watermark the image, and the watermark may be defined as W(x) and its complement [1−W(x)] in counter-phase rotations of successive lines in pairs of frames. The watermark information is applied in relatively still portions of the image with sufficient lightness level. A receiver includes a watermark detector that has a priori information about the watermark. The watermark detector examines specific regions of the displayed image over time, and tests the regions for the watermark during time intervals when the image remains relatively still.

摘要翻译： 通过根据应用于例如每个修改的帧的连续行的时空模式，跨越显示器改变一个或多个显示特性，将通道插入到用于图像的帧序列中。 可以使用信道对图像进行水印，并且在成对的帧中的相继行的相位旋转中，水印可被定义为W（x）及其补码[1-W（x）]。 水印信息以足够的亮度水平施加在图像的相对静止部分中。 接收机包括具有关于水印的先验信息的水印检测器。 水印检测器随时间检查显示图像的特定区域，并且在图像保持相对静止的时间间隔期间测试水印的区域。

公开(公告)号：US08532371B2

公开(公告)日：2013-09-10

申请号：US12897583

申请日：2010-10-04

申请人： Niraj Agarwal ,  Michael H. Brill

发明人： Niraj Agarwal ,  Michael H. Brill

IPC分类号： G06K9/00

CPC分类号： H04N1/6033 ,  H04N1/6088

摘要： A method for evaluating a color of a sample includes acquiring an image having a plurality of pixels from a sample and a plurality of pixels from known color calibration patches. The image is color calibrated using the known color patches to endow the pixels from the sample with the tristimulus values they would have under one or more known illuminants. The calibrated image is transmitted, together with metadata, to a remote location where further computations and an approval process are performed. The further computations include comparing all of the pixels in the image of a standard that are of a first color to all pixels of a second color in the similarly calibrated image of the sample, where the second color is a color in the image of the sample that is most similar to the first color from the image of the standard.

摘要翻译： 用于评估样本的颜色的方法包括从已知颜色校准块的样本和多个像素获取具有多个像素的图像。 图像使用已知的色标进行颜色校准，以使来自样品的像素具有它们在一种或多种已知光源下具有的三刺激值。 经校准的图像与元数据一起发送到进行进一步计算和批准处理的远程位置。 进一步的计算包括在样本的类似校准图像中比较第一颜色的标准图像中的所有像素与第二颜色的所有像素，其中第二颜色是样本图像中的颜色 这与标准图像中的第一种颜色最相似。