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1.发明授权Slidable door and sidewall associated with tents, awnings, and other protective enclosures 失效与帐篷，遮阳篷和其他保护罩相关的可滑动的门和侧壁公开(公告)号：US06484739B1
公开(公告)日：2002-11-26
申请号：US09387308
申请日：1999-08-31
申请人： Michael P. Sofie , John A. Barrett
发明人： Michael P. Sofie , John A. Barrett
IPC分类号： E04H1558
摘要： The invention is generally directed to a foldable door and sidewall, and more particularly, to a foldable door and sidewall suitable for use with tents, awnings, restaurant patio shielding, and other protective enclosures. The invention is also directed to methods for retrofitting a protective enclosure (e.g., frame structure associated with a collapsible tent) with a foldable door or sidewall, as well as to kits for accomplishing the same. In one embodiment, a foldable door or sidewall is disclosed that is adapted for detachable attachment with a protective enclosure, wherein the foldable door or sidewall comprises a flexible sheet having a continuous perimeter that defines a plurality of discrete door or sidewall edges, wherein at least one of the door or sidewall edges is adapted to slidably engage a slide track, and at least one magnet integrally associated with at least one of the door or sidewall edges of the flexible sheet, wherein the door or sidewall edge having the at least one magnet integrally associated therewith is not the same as the door or sidewall edge adapted to slidably engage the slide track.
摘要翻译： 本发明通常涉及可折叠的门和侧壁，更具体地涉及适用于帐篷，遮阳篷，餐厅露台屏蔽和其它保护罩的可折叠门和侧壁。 本发明还涉及用可折叠的门或侧壁改装保护性外壳（例如与可折叠帐篷相关联的框架结构）以及用于完成其的套件的方法。 在一个实施例中，公开了一种可折叠的门或侧壁，其适于与保护性外壳可拆卸地连接，其中可折叠门或侧壁包括具有限定多个离散门或侧壁边缘的连续周界的柔性片，其中至少 门或侧壁边缘中的一个适于滑动地接合滑动轨道，以及与柔性片材的门或侧壁边缘中的至少一个整体相关联的至少一个磁体，其中门或侧壁边缘具有至少一个磁体 与其整体相关联的门与侧壁边缘不同于适于滑动地接合滑轨的门或侧壁边缘。
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公开(公告)号：USD372287S
公开(公告)日：1996-07-30
申请号：US33867
申请日：1995-01-23
申请人： Michael P. Sofie , John A. Barrett
设计人： Michael P. Sofie , John A. Barrett
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3.发明授权Method for adhering a flexible sheet to a semi-rigid thermoplastic resinous sheet and products relating thereto 失效将柔性片粘附到半刚性热塑性树脂片和与其相关的产品的方法
公开(公告)号：US5851637A
公开(公告)日：1998-12-22
申请号：US887485
申请日：1997-07-02
申请人： Michael P. Sofie , John A. Barrett
发明人： Michael P. Sofie , John A. Barrett
CPC分类号： B60J1/1815 , B63B17/02 , C08J5/124 , C09J5/02 , E04H15/54 , C08L63/00 , C09J2463/00 , Y10T156/10 , Y10T428/169 , Y10T428/24777 , Y10T428/24826
摘要： There is disclosed a method for adhering a flexible sheet (such as a fibrous or resinous sheet) to a semi-rigid thermoplastic resinous sheet (such as a polycarbonate or acrylic sheet). In one embodiment, the method comprises the steps of contacting an edge surface of a flexible fibrous sheet with a thermosetting resin and allowing the resin to cure to yield a unified surface, applying an adhesive along of an edge surface of the semi-rigid sheet to yield an adhesive surface and contacting the unified surface of the flexible fibrous sheet with the adhesive surface of the semi-rigid sheet to adhere the flexible fibrous sheet to the semi-rigid sheet. The products made by this method are suitable for a variety of applications, including use as boat and dwelling enclosures.
摘要翻译： 公开了一种将柔性片（如纤维或树脂片）粘附到半刚性热塑性树脂片（例如聚碳酸酯或丙烯酸片）上的方法。 在一个实施方案中，该方法包括以下步骤：使柔性纤维片材的边缘表面与热固性树脂接触，并允许树脂固化以产生统一的表面，沿着半刚性片材的边缘表面施加粘合剂到 产生粘合表面并使柔性纤维片的统一表面与半刚性片的粘合表面接触，以将柔性纤维片粘附到半刚性片上。 通过这种方法制成的产品适用于各种应用，包括用作船和住宅外壳。
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4.发明授权Method for adhering a flexible sheet to a semi-rigid thermoplastic resinous sheet and products relating thereto 失效将柔性片粘附到半刚性热塑性树脂片和与其相关的产品的方法
公开(公告)号：US5660916A
公开(公告)日：1997-08-26
申请号：US520929
申请日：1995-08-30
申请人： Michael P. Sofie , John A. Barrett
发明人： Michael P. Sofie , John A. Barrett
CPC分类号： B60J1/1815 , B63B17/02 , C08J5/124 , C09J5/02 , E04H15/54 , C08L63/00 , C09J2463/00 , Y10T156/10 , Y10T428/169 , Y10T428/24777 , Y10T428/24826
摘要： There is disclosed a method for adhering a flexible sheet (such as a fibrous or resinous sheet) to a semi-rigid thermoplastic resinous sheet (such as a polycarbonate or acrylic sheet). In one embodiment, the method comprises the steps of contacting an edge surface of a flexible fibrous sheet with a thermosetting resin and allowing the resin to cure to yield a unified surface, applying an adhesive along of an edge surface of the semi-rigid sheet to yield an adhesive surface and contacting the unified surface of the flexible fibrous sheet with the adhesive surface of the semi-rigid sheet to adhere the flexible fibrous sheet to the semi-rigid sheet. The products made by this method are suitable for a variety of applications, including use as boat and dwelling enclosures.
摘要翻译： 公开了一种将柔性片（如纤维或树脂片）粘附到半刚性热塑性树脂片（例如聚碳酸酯或丙烯酸片）上的方法。 在一个实施方案中，该方法包括以下步骤：使柔性纤维片材的边缘表面与热固性树脂接触，并允许树脂固化以产生统一的表面，沿着半刚性片材的边缘表面施加粘合剂到 产生粘合表面并使柔性纤维片的统一表面与半刚性片的粘合表面接触，以将柔性纤维片粘附到半刚性片上。 通过这种方法制成的产品适用于各种应用，包括用作船和住宅外壳。
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5.发明授权Method for adhering a flexible fibrous sheet to a semi-rigid thermoplastic resinous sheet and products relating thereto 失效将柔性纤维片粘附到半刚性热塑性树脂片和与其相关的产品的方法
公开(公告)号：US5472771A
公开(公告)日：1995-12-05
申请号：US176032
申请日：1993-12-30
申请人： Michael P. Sofie , John A. Barrett
发明人： Michael P. Sofie , John A. Barrett
CPC分类号： B60J1/1815 , B63B17/02 , C08J5/124 , C09J5/02 , E04H15/54 , C08L63/00 , C09J2463/00 , Y10T156/10 , Y10T428/169 , Y10T428/24777 , Y10T428/24826
摘要： There is disclosed a method for adhering a flexible fibrous sheet (such as a canvas) to a semi-rigid thermoplastic resinous sheet (such as a polycarbonate or acrylic sheet). The method comprises the steps of contacting an edge surface of the flexible fibrous sheet with a thermosetting resin and allowing the resin to cure to yield a unified surface, applying an adhesive along of an edge surface of the semi-rigid sheet to yield an adhesive surface and contacting the unified surface of the flexible fibrous sheet with the adhesive surface of the semi-rigid sheet to adhere the flexible fibrous sheet to the semi-rigid sheet. The products made by this method are suitable for a variety of applications, including use as boat and dwelling enclosures.
摘要翻译： 公开了将柔性纤维片（如帆布）粘合到半刚性热塑性树脂片（例如聚碳酸酯或丙烯酸类片材）上的方法。 该方法包括以下步骤：使柔性纤维片材的边缘表面与热固性树脂接触，并使树脂固化以产生统一的表面，沿着半刚性片材的边缘表面施加粘合剂以产生粘合表面 并将柔性纤维片的统一表面与半刚性片的粘合表面接触，以将柔性纤维片粘附到半刚性片上。 通过这种方法制成的产品适用于各种应用，包括用作船和住宅外壳。
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公开(公告)号：US07018611B2
公开(公告)日：2006-03-28
申请号：US10281015
申请日：2002-10-26
CPC分类号： A61K49/0002 , A61K49/04 , A61K49/085 , A61K49/10 , A61K49/223 , A61K51/0455 , A61K51/0459 , A61K51/0497 , C07D401/12 , C07D401/14
摘要： The present invention describes novel compounds of the formula: (Q)d—Ln—Ch, useful for the diagnosis and treatment of cancer, methods of imaging tumors in a patient, and methods of treating cancer in a patient. The present invention also provides novel compounds useful for monitoring therapeutic angiogenesis treatment and destruction of new angiogenic vasculature. The present invention further provides novel compounds useful for imaging atherosclerosis, restenosis, cardiac ischemia, and myocardial reperfusion injury. The present invention still further provides novel compounds useful for the treatment of rheumatoid arthritis. The pharmaceuticals are comprised of a targeting moiety that binds to a receptor that is upregulated during angiogenesis, an optional linking group, and a therapeutically effective radioisotope or diagnostically effective imageable moiety. The imageable moiety is a gamma ray or positron emitting radioisotope, a magnetic resonance imaging contrast agent, an X-ray contrast agent, or an ultrasound contrast agent.
摘要翻译： 本发明描述了新的下式化合物：<？in-line-formula description =“In-line Formulas”end =“lead”？>（Q） 对于癌症的诊断和治疗有用的<？in-line-formula description =“在线公式”end =“tail”？>，肿瘤成像方法 患者，以及在患者中治疗癌症的方法。 本发明还提供了可用于监测治疗性血管生成治疗和破坏新的血管生成脉管系统的新型化合物。 本发明还提供可用于成像动脉粥样硬化，再狭窄，心脏缺血和心肌再灌注损伤的新型化合物。 本发明还提供了可用于治疗类风湿性关节炎的新化合物。 药物由与血管发生期间上调的受体结合的靶向部分，任选的连接基团和治疗有效的放射性同位素或诊断上有效的可成像部分组成。 可成像部分是伽马射线或正电子发射放射性同位素，磁共振成像造影剂，X射线造影剂或超声造影剂。
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公开(公告)号：US06416733B1
公开(公告)日：2002-07-09
申请号：US08943659
申请日：1997-10-03
申请人： John A. Barrett , Edward H. Cheesman , Thomas D. Harris , Shuang Liu , Milind Rajopadhye , Michael Sworin
发明人： John A. Barrett , Edward H. Cheesman , Thomas D. Harris , Shuang Liu , Milind Rajopadhye , Michael Sworin
IPC分类号： A61K5100
CPC分类号： A61K51/0497 , A61K51/0455 , A61K51/0478 , C07C59/90 , C07D213/64 , C07D213/71 , C07D213/77 , C07D213/82 , C07D401/06 , C07D401/12 , C07D401/14 , C07D405/04 , C07D405/12 , C07D405/14 , C07F13/005
摘要： The present invention provides novel radiopharmaceuticals useful for the diagnosis of infection and inflammation, reagents and kits useful for preparing the radiopharmaceuticals, methods of imaging sites of infection and/or inflammation in a patient, and methods of diagnosing diseases associated with infection or inflammation in patients in need of such diagnosis. The radiopharmaceuticals bind in vivo to the leukotriene B4 (LTB4) receptor on the surface of leukocytes which accumulate at the site of infection and inflammation. The reagents provided by this invention are also useful for the treatment of diseases associated with infection and inflammation.
摘要翻译： 本发明提供了可用于诊断感染和炎症的新型放射性药物，可用于制备放射性药物的试剂和试剂盒，成像患者感染和/或炎症部位成像方法以及诊断患者感染或炎症相关疾病的方法 需要这样的诊断。 放射性药物在体内结合白细胞表面的白细胞三烯B4（LTB4）受体，其在感染和炎症部位积聚。 本发明提供的试剂也可用于治疗与感染和炎症相关的疾病。
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公开(公告)号：US06511649B1
公开(公告)日：2003-01-28
申请号：US09599364
申请日：2000-06-21
IPC分类号： A61K5100
CPC分类号： A61K49/0002 , A61K49/04 , A61K49/085 , A61K49/10 , A61K49/223 , A61K51/0455 , A61K51/0459 , A61K51/0497 , C07D401/12 , C07D401/14
摘要： The present invention describes novel compounds of the formula: (Q)d—Ln—Ch, useful for the diagnosis and treatment of cancer, methods of imaging tumors in a patient, and methods of treating cancer in a patient. The present invention also provides novel compounds useful for monitoring therapeutic angiogenesis treatment and destruction of new angiogenic vasculature. The present invention further provides novel compounds useful for imaging atherosclerosis, restenosis, cardiac ischemia, and myocardial reperfusion injury. The present invention still further provides novel compounds useful for the treatment of rheumatoid arthritis. The pharmaceuticals are comprised of a targeting moiety that binds to a receptor that is upregulated during angiogenesis, an optional linking group, and a therapeutically effective radioisotope or diagnostically effective imageable moiety. The imageable moiety is a gamma ray or positron emitting radioisotope, a magnetic resonance imaging contrast agent, an X-ray contrast agent, or an ultrasound contrast agent.
摘要翻译： 本发明描述了新的下式化合物：可用于癌症的诊断和治疗，对患者肿瘤成像的方法，以及治疗患者癌症的方法。 本发明还提供了可用于监测治疗性血管生成治疗和破坏新的血管生成脉管系统的新型化合物。 本发明还提供可用于成像动脉粥样硬化，再狭窄，心脏缺血和心肌再灌注损伤的新型化合物。 本发明还提供了可用于治疗类风湿性关节炎的新化合物。 药物由与血管发生期间上调的受体结合的靶向部分，任选的连接基团和治疗有效的放射性同位素或诊断上有效的可成像部分组成。 可成像部分是伽马射线或正电子发射放射性同位素，磁共振成像造影剂，X射线造影剂或超声造影剂。
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公开(公告)号：US07052673B2
公开(公告)日：2006-05-30
申请号：US10622246
申请日：2003-07-18
申请人： Milind Rajopadhye , D. Scott Edwards , John A. Barrett , Alan P. Carpenter, Jr. , Thomas D Harris , Stuart D Heminway , Shuang Liu , Singh R Prahlad
发明人： Milind Rajopadhye , D. Scott Edwards , John A. Barrett , Alan P. Carpenter, Jr. , Thomas D Harris , Stuart D Heminway , Shuang Liu , Singh R Prahlad
CPC分类号： C07D401/14 , A61K38/00 , A61K45/06 , A61K49/0002 , A61K49/227 , A61K51/082 , A61K51/088 , C07D401/12 , C07K7/06 , C07K7/08 , C07K7/64
摘要： The present invention describes novel compounds of the formula: (Q)d—Ln—Ch, useful for the diagnosis and treatment of cancer, methods of imaging tumors in a patient, and methods of treating cancer in a patient. The present invention also provides novel compounds useful for monitoring therapeutic angiogenesis treatment and destruction of new angiogenic vasculature. The pharmaceuticals are comprised of a targeting moiety that binds to a receptor that is upregulated during angiogenesis, an optional linking group, and a therapeutically effective radioisotope or diagnostically effective imageable moiety. The imageable moiety is a gamma ray or positron emitting radioisotope, a magnetic resonance imaging contrast agent, an X-ray contrast agent, or an ultrasound contrast agent.
摘要翻译： 本发明描述了新的下式化合物：<？in-line-formula description =“In-line Formulas”end =“lead”？>（Q） 对于癌症的诊断和治疗有用的<？in-line-formula description =“在线公式”end =“tail”？>，肿瘤成像方法 患者，以及在患者中治疗癌症的方法。 本发明还提供了可用于监测治疗性血管生成治疗和破坏新的血管生成脉管系统的新型化合物。 药物由与血管发生期间上调的受体结合的靶向部分，任选的连接基团和治疗有效的放射性同位素或诊断上有效的可成像部分组成。 可成像部分是伽马射线或正电子发射放射性同位素，磁共振成像造影剂，X射线造影剂或超声造影剂。
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公开(公告)号：US07090828B2
公开(公告)日：2006-08-15
申请号：US10348268
申请日：2003-01-21
申请人： Edward H. Cheesman , John A. Barrett , Alan P. Carpenter, Jr. , Milind Rajopadhye , Michael Sworin
发明人： Edward H. Cheesman , John A. Barrett , Alan P. Carpenter, Jr. , Milind Rajopadhye , Michael Sworin
CPC分类号： A61K49/0002 , A61K51/0497 , C07D401/12 , C07D401/14 , C07D403/12 , C07D403/14 , C07K5/0207 , C07K5/0806 , C07K5/0821 , C07K5/1008 , C07K5/1024 , C07K7/02 , C07K7/06 , C07K7/64 , C07K9/003
摘要： The present invention describes novel compounds of the formula: (Q)d-Ln-Ch, useful for the diagnosis and treatment of cancer, methods of imaging tumors in a patient, and methods of treating cancer in a patient. The present invention also provides novel compounds useful for monitoring therapeutic angiogenesis treatment and destruction of new angiogenic vasculature. The present invention further provides novel compounds useful for imaging atherosclerosis, restenosis, cardiac ischemia and myocardial reperfusion injury. The present invention still further provides novel compounds useful for the treatment of rheumatoid arthritis. The pharmaceuticals are comprised of a targeting moiety that binds to a receptor that is upregulated during angiogenesis, an optional linking group, and a therapeutically effective radioisotope or diagnostically effective imageable moiety. The imageable moiety is a gamma ray or positron emitting radioisotope, a magnetic resonance imaging contrast agent, an X-ray contrast agent, or an ultrasound contrast agent.
摘要翻译： 本发明描述了新的下式化合物：<？in-line-formula description =“In-line Formulas”end =“lead”？>（Q） 对于癌症的诊断和治疗有用的<？in-line-formula description =“在线公式”end =“tail”？>，肿瘤成像方法 患者，以及在患者中治疗癌症的方法。 本发明还提供了可用于监测治疗性血管生成治疗和破坏新的血管生成脉管系统的新型化合物。 本发明还提供了用于成像动脉粥样硬化，再狭窄，心脏缺血和心肌再灌注损伤的新型化合物。 本发明还提供了可用于治疗类风湿性关节炎的新化合物。 药物由与血管发生期间上调的受体结合的靶向部分，任选的连接基团和治疗有效的放射性同位素或诊断上有效的可成像部分组成。 可成像部分是伽马射线或正电子发射放射性同位素，磁共振成像造影剂，X射线造影剂或超声造影剂。
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