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公开(公告)号：US06868287B1
公开(公告)日：2005-03-15
申请号：US09505458
申请日：2000-02-11
CPC分类号： A61N1/326 , A61N1/0587 , A61N1/3684
摘要： The invention provides a method of treating a heart to remodel gap junctions, obtain gap junctional remodeling and/or alteration or effective refractory period comprising contacting linked multiple electrode pairs to an epicardial surface of a heart, and connecting the electrode pairs to a pacemaker to apply periodic electrical signals to the epicardial surface through the electrode pairs, the signals being applied for a sufficient time and having characteristics sufficient to remodel gap junctions, obtain gap junctional remodeling and/or alteration of effective refractory period in the heart. The invention also provides a device comprising a strip of electrode material having mounted thereon linked multiple electrode pairs arranged in two columns.
摘要翻译： 本发明提供了一种治疗心脏以重建间隙连接，获得间隙连接重建和/或改变或有效的不应期的方法，包括将连接的多个电极对接触到心脏的心外膜表面，以及将电极对连接到起搏器以施加 通过电极对向心外膜表面施加周期性电信号，信号被施加足够的时间并具有足以改造间隙连接的特征，获得心脏中有效不应期的间隙连接重构和/或改变。 本发明还提供了一种装置，其包括电极材料条，其上安装有连接的多个电极对，其布置成两列。
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公开(公告)号：US11197971B2
公开(公告)日：2021-12-14
申请号：US16541436
申请日：2019-08-15
申请人： Yoram Palti
发明人： Yoram Palti
IPC分类号： A61M16/16 , A61M16/10 , F24F11/74 , F24F6/04 , F24F110/20 , F24F110/10
摘要： A humidifier uses a field of hydrophobic, nanotubes (e.g., vertically aligned carbon nanotubes) to humidify a gas. Voids in the field form liquid flow channels that are wide enough for liquid water to pass through. The nanotubes are spaced close enough to each other to prevent the water from escaping the channels. Water in the channels is absorbed by gas that flows and/or diffuses between the nanotubes. Humidity levels in the gas can be measured and controlled to a desired level by controlling the rate of flow of gas through the humidifier, controlling heating of the gas, and/or adjusting the total area of molecular transfer from the water to the gas by providing multiple banks of nanotubes and controlling the number of banks through which the gas flows.
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公开(公告)号：US10780287B2
公开(公告)日：2020-09-22
申请号：US16499287
申请日：2018-04-05
申请人： Yoram Palti
发明人： Yoram Palti
摘要： An implantable device that (a) has an analog input configured to detect analog electrical signals and (b) is configured to accept RF commands can be retrofitted to prevent unauthorized access by modifying the software of the implantable device to (1) accept control commands that arrive via the analog input and (2) ignore control commands that arrive via the RF transceiver. Ultrasound communications can then be detected and inductively coupled onto a lead that is connected to the analog input. In some embodiments, the modified implantable device can only be controlled via ultrasound signals at all times to improve security. In other embodiments, the modified implantable device can only be controlled via non-ultrasound signals (e.g., RF signals) for short periods of time after the system has been unlocked in response to receipt of a specific ultrasound signal.
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公开(公告)号：US09138522B2
公开(公告)日：2015-09-22
申请号：US14331608
申请日：2014-07-15
申请人： Yoram Palti
发明人： Yoram Palti
CPC分类号： A61M1/1698 , A61M2202/0208 , A61M2202/0225 , B01D69/04
摘要： Blood or other fluids can be caused to interact with a gas by providing a plurality of fluid flow channels that are surrounded by nanotubes, each of the channels having an inflow end and an outflow end, wherein each of the channels is wide enough for the blood to flow through, and wherein the nanotubes are spaced close enough to each other to retain the fluid within the channels when the blood is flowing through the channels. The fluid is then passed through the through the channels while a gas is passed through the spaces between the nanotubes outside the fluid flow channels. This permits the gas to interact with the fluid in the channels.
摘要翻译： 可以通过提供由纳米管围绕的多个流体流动通道使血液或其它流体与气体相互作用，每个通道具有流入端和流出端，其中每个通道足够宽以使血液 流过，并且其中，当血液流过通道时，纳米管彼此间隔足够近以将流体保持在通道内。 然后使流体通过通道，同时气体通过流体流动通道外的纳米管之间的空间。 这允许气体与通道中的流体相互作用。
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公开(公告)号：US20140275967A1
公开(公告)日：2014-09-18
申请号：US14179346
申请日：2014-02-12
申请人： Yoram Palti
发明人： Yoram Palti
IPC分类号： A61B8/08
CPC分类号： A61B8/0841 , A61B5/064 , A61B5/6861 , A61B8/4461 , A61B8/488 , A61B8/5261 , A61B90/39 , A61B2090/3925
摘要： An apparatus, method and system for detecting a position within a body are provided. A dipole that is free to rotate or oscillate within a capsule is inserted at a target location within the body. The dipole can be either electric or magnetic, and the dipole rotates or oscillates within the capsule when an alternating or rotating electric or magnetic field is applied in the vicinity of the dipole. Ultrasound energy is impinged upon the target location and a position of the dipole is determined based on detected ultrasound reflections.
摘要翻译： 提供了一种用于检测身体内的位置的装置，方法和系统。 在胶囊内自由旋转或振荡的偶极子插入到体内的目标位置。 当在偶极子附近施加交替或旋转的电场或磁场时，偶极子可以是电的或磁的，并且偶极子在胶囊内旋转或振荡。 超声能量撞击目标位置，并且基于检测到的超声反射来确定偶极子的位置。
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公开(公告)号：US08447396B2
公开(公告)日：2013-05-21
申请号：US13428887
申请日：2012-03-23
申请人： Yoram Palti , Moshe Giladi
发明人： Yoram Palti , Moshe Giladi
IPC分类号： A61N1/18
摘要： Cells that are in the process division are vulnerable to damage by AC electric fields that have specific frequency and field strength characteristics. The selective destruction of rapidly dividing cells can therefore be accomplished by imposing an AC electric field in a target region for extended periods of time. Some of the cells that divide while the field is applied will be damaged, but the cells that do not divide will not be harmed. This selectively damages rapidly dividing cells like bacteria, but does not harm normal cells that are not dividing. Since the vulnerability of the dividing cells is strongly related to the alignment between the long axis of the dividing cells and the lines of force of the electric field, improved results can be obtained when the field is sequentially imposed in different directions.
摘要翻译： 处于过程部分的电池容易受到具有特定频率和场强特性的交流电场的损害。 因此，快速分裂细胞的选择性破坏可以通过在目标区域中长时间施加AC电场来实现。 一些应用场地分割的细胞将被破坏，但不分裂的细胞不会受到伤害。 这有选择地损害快速分裂的细胞，如细菌，但不会伤害不分裂的正常细胞。 由于分割单元的脆弱性与分割单元的长轴与电场的力线之间的对准强烈相关，所以当场依次施加在不同的方向时，可以获得改进的结果。
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公开(公告)号：US20120323094A1
公开(公告)日：2012-12-20
申请号：US13527708
申请日：2012-06-20
申请人： Yoram Palti
发明人： Yoram Palti
IPC分类号： A61B5/00
CPC分类号： G01N33/5073 , A61B5/14532 , A61B5/1459 , A61B5/686 , G01N33/66
摘要： Methods and apparatuses for monitoring the level of glucose or other constituents in live subjects are disclosed. Stem cells are obtained from the subject and processed into cells that change their optical characteristics in response to a level of the constituent. The responsive cells are formed into clusters and implanted into in the subject's body at locations that permit optical monitoring from outside the subject's body. The implanted cell clusters are illuminated and the reflected illumination from each of the cell clusters is detected. Changes in the optical characteristics of the cell clusters that correspond to the responses of the cell clusters are identified, and the identified changes are mapped to a constituent level based on calibration data for each cell cluster. An indication of the constituent level in the subject is then output.
摘要翻译： 公开了用于监测活体受试者中葡萄糖或其他成分水平的方法和装置。 从受试者获得干细胞并将其处理成响应成分水平改变其光学特性的细胞。 响应细胞被形成簇并且在允许从对象体外外部进行光学监测的位置处植入受试者的身体。 照射植入的细胞簇，并检测来自每个细胞簇的反射照明。 识别与细胞簇的响应对应的细胞簇的光学特性的变化，并且基于每个细胞簇的校准数据将鉴定的变化映射到组成水平。 然后输出主体中的构成等级的指示。
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公开(公告)号：US07890183B2
公开(公告)日：2011-02-15
申请号：US12190886
申请日：2008-08-13
申请人： Yoram Palti , Moshe Giladi
发明人： Yoram Palti , Moshe Giladi
IPC分类号： A61N1/00
摘要： Cells that are in the process division are vulnerable to damage by AC electric fields that have specific frequency and field strength characteristics. The selective disruption of rapidly dividing cells can therefore be accomplished by imposing an AC electric field in a target region for extended periods of time. Some of the cells that divide while the field is applied will be damaged, but the cells that do not divide will not be harmed. This selectively damages or disrupts rapidly dividing cells like parasites, but does not harm normal cells that are not dividing.
摘要翻译： 处于过程部分的电池容易受到具有特定频率和场强特性的交流电场的损害。 因此，快速分裂细胞的选择性破坏可以通过在目标区域中长时间施加AC电场来实现。 一些应用场地分割的细胞将被破坏，但不分裂的细胞不会受到伤害。 这会选择性地损害或破坏快速分裂的细胞，如寄生虫，但不会损害不分裂的正常细胞。
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9.发明申请公开(公告)号：US20100324547A1
公开(公告)日：2010-12-23
申请号：US12851761
申请日：2010-08-06
申请人： Yoram Palti
发明人： Yoram Palti
摘要： AC electric fields at particular frequencies and field strengths have been shown to be effective for destroying rapidly proliferating cells such as cancer cells. The effectiveness of such fields is improved when the field is sequentially switched between two or more different directions. The effectiveness of such fields can be improved even further by choosing the rate at which the field is switched between the various directions.
摘要翻译： 已经显示特定频率和场强的AC电场对于破坏快速增殖的细胞如癌细胞是有效的。 当场在两个或更多个不同方向之间顺序切换时，这种场的有效性得到改善。 通过选择在各个方向之间切换的速率，可进一步提高这些领域的有效性。
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公开(公告)号：US20100282528A1
公开(公告)日：2010-11-11
申请号：US12774200
申请日：2010-05-05
申请人： Yoram Palti
发明人： Yoram Palti
CPC分类号： H02K7/025 , B60K1/04 , B60K8/00 , B60L50/30 , B60L2200/26 , H02K7/09 , Y02E60/16 , Y02T10/6204 , Y02T10/641 , Y02T10/7027 , Y02T10/7033
摘要： An electro-mechanical battery includes a support member. The electro-mechanical battery also includes a first rotating frame. The first rotating frame is supported by the support member and configured to rotate about an axis. The electro-mechanical battery also includes at least one battery, which is supported by the first rotating frame. A mechanical coupling system is configured to store rotational kinetic energy in the first rotating frame and facilitate retrieval of the rotational kinetic energy. The electro-mechanical battery also includes a rotating electrical connection between the support member and the at least one battery. The rotating electrical connection is configured to permit charging of the at least one battery and discharging of the at least one battery while the first rotating frame is rotating.
摘要翻译： 机电电池包括支撑构件。 机电电池还包括第一旋转框架。 第一旋转框架由支撑构件支撑并且构造成绕轴线旋转。 机电电池还包括由第一旋转框架支撑的至少一个电池。 机械联接系统被配置为将旋转动能存储在第一旋转框架中并且促进旋转动能的取回。 机电电池还包括在支撑构件和至少一个电池之间的旋转电连接。 旋转电连接被配置为允许至少一个电池充电并且当第一旋转框架旋转时至少一个电池的放电。
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