公开(公告)号：US20240341691A1

公开(公告)日：2024-10-17

申请号：US18753295

申请日：2024-06-25

申请人： ENTERASENSE LIMITED

发明人： Maria Chiara DICARLO ,  Donal DEVERY

IPC分类号： A61B5/00 ,  A61B5/07 ,  A61B5/1459

CPC分类号： A61B5/6861 ,  A61B5/0071 ,  A61B5/073 ,  A61B5/1459 ,  A61B5/7225

摘要： A biosensor system has a capsule with a housing configured for ingesting in a mammal GI tract, being cylindrical with domed ends. The housing forms an external space akin to a “cut-out” shape with two opposing transparent walls facing each other in the longitudinal direction and a base wall facing radially. An LED emitter emits at a number of wavelengths in time sequence, and radiation is detected by a photo-detector via the wall which forms a concave lens. An antenna is for wireless transmission of data to an external device and is in the form of conical spiral in an overall conical shape, located for optimum space efficiency in a domed end. A battery compartment is at the opposed end of the housing, separated from the antenna by the external space.

公开(公告)号：US12109007B2

公开(公告)日：2024-10-08

申请号：US18492038

申请日：2023-10-23

申请人： Medtronic, Inc.

发明人： Alfonso Aranda Hernandez ,  Richard Cornelussen ,  Mirko de Melis ,  Richard Sutton ,  Berthold Stegemann

IPC分类号： A61B5/0205 ,  A61B5/00 ,  A61B5/024 ,  A61B5/07 ,  A61B5/08 ,  A61B5/11 ,  A61B5/282 ,  A61B5/349 ,  A61N1/375

CPC分类号： A61B5/0205 ,  A61B5/076 ,  A61B5/686 ,  A61B5/6861 ,  A61B5/7282 ,  A61B5/02405 ,  A61B5/0816 ,  A61B5/1116 ,  A61B5/1118 ,  A61B5/282 ,  A61N1/3756

摘要： In some examples, determining a heart failure status using a medical device comprising one or more sensors includes determining a first value of a heart beat variability metric of a patient while an activity state of a patient satisfies an inactivity criterion based on a signal received from the one or more sensors, and determining, within a predetermined period of time after further determining that the activity state of the patient no longer satisfies the inactivity criterion, a second value of the heart beat variability metric while the activity state of the patient no longer satisfies the inactivity criterion based on the signal. A difference between the first value of the heart beat variability metric and the second value of the heart beat variability metric may be determined and the heart failure status of the patient may be determined based on the difference.

公开(公告)号：US20240315560A1

公开(公告)日：2024-09-26

申请号：US18734231

申请日：2024-06-05

申请人： EFFERENT LABS, INC.

发明人： Spencer Z. Rosero ,  William K. Rader

IPC分类号： A61B5/00 ,  A61B5/01 ,  A61B5/021 ,  A61B5/145 ,  A61B5/318 ,  A61L27/36

CPC分类号： A61B5/0031 ,  A61B5/0017 ,  A61B5/01 ,  A61B5/021 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/318 ,  A61B5/6861 ,  A61L27/3604

摘要： An implantable device for monitoring physiological changes in a patient is provided. The device can include a vessel adapted to being implanted within a patient's body; a chamber having a cell layer and capable of being secured to the vessel; a light source for shining light onto the cell layer; and a reader for detecting and/or decoding signals from the cell layer to monitor physiological changes in the patient. The device is capable of engaging in a two-way communication with a second device through transmission of one or more electromagnetic signals through at least a portion of the patient's body.

公开(公告)号：US12070321B2

公开(公告)日：2024-08-27

申请号：US17348954

申请日：2021-06-16

申请人： Boston Scientific Scimed, Inc.

发明人： George Wilfred Duval ,  Namita M. Kallur

IPC分类号： A61B5/00 ,  A61B5/07 ,  A61B5/107 ,  A61B5/026 ,  A61B5/0295

CPC分类号： A61B5/4216 ,  A61B5/073 ,  A61B5/1076 ,  A61B5/4238 ,  A61B5/4255 ,  A61B5/7264 ,  A61B5/0086 ,  A61B5/0261 ,  A61B5/0295 ,  A61B5/1072 ,  A61B5/4233 ,  A61B5/6861

摘要： A method for evaluating a gastrointestinal tract of a subject may comprise using a sensor located in the subject to obtain data regarding qualities of a tissue of the gastrointestinal tract; using the obtained data, determining a measure of perfusion of blood in the tissue; using the obtained data, determining a measure of thickness of the tissue; using the measure of perfusion and the measure of thickness, determining a measure of inflammation of the tissue; and using one or more of the measure of perfusion, the measure of thickness, and the measure of inflammation, classifying a state of the tissue.

公开(公告)号：US12011252B2

公开(公告)日：2024-06-18

申请号：US17233776

申请日：2021-04-19

申请人： Teliatry, Inc.

发明人： Rahul Saini ,  Dane William Grasse ,  Vishnoukumaar Sivaji

IPC分类号： A61B5/0215 ,  A61B5/00 ,  A61B5/0538 ,  A61B5/07 ,  A61B5/145 ,  A61B5/1473 ,  A61B6/42 ,  A61B8/12 ,  H02J50/20

CPC分类号： A61B5/02158 ,  A61B5/0031 ,  A61B5/0538 ,  A61B5/076 ,  A61B5/14539 ,  A61B5/1473 ,  A61B5/6861 ,  A61B5/6898 ,  A61B6/425 ,  A61B8/12 ,  H02J50/20 ,  A61B2560/0214 ,  A61B2562/0233 ,  A61B2562/0247 ,  A61B2562/0261 ,  A61B2562/0271 ,  A61B2562/164

摘要： In one embodiment, a sensor includes a capsule having a cavity and a sheath, a transducer coupled to electronic circuitry in the cavity, and a clip outside the capsule. The capsule and the clip are configured to hold in vivo an object within an opening between the capsule and the clip. The transducer is configured to detect an incoming signal indicative of a physiological parameter of the object being held, and the electronic circuitry is configured to wirelessly transmit a signal containing information about the physiological parameter obtained from the incoming signal. The sensor is part of a measurement system to measure the physiological parameter. Another embodiment describes a method using the measurement system.

公开(公告)号：US20240148299A1

公开(公告)日：2024-05-09

申请号：US18549953

申请日：2022-03-14

申请人： CELERO SYSTEMS, INC.

发明人： Benjamin D. Pless ,  Daniel Bacher ,  Shannon Schuetz

IPC分类号： A61B5/16 ,  A61B5/00 ,  A61B5/053 ,  A61B5/07

CPC分类号： A61B5/165 ,  A61B5/053 ,  A61B5/073 ,  A61B5/4839 ,  A61B5/6861 ,  A61B2562/162

摘要： An anxiety monitor and treatment system is provided comprising an ingestible housing and at least one sensor configured to detect a physiological parameter indicative of anxiety. The system further includes a controller operatively coupled to the least one sensor. The controller is programmed to receive the physiological parameter and prepare the physiological parameter for transmission from the subject, analysis of the physiological parameter, or both.

公开(公告)号：US20240081654A1

公开(公告)日：2024-03-14

申请号：US18554527

申请日：2022-04-06

申请人： NICHE BIOMEDICAL, INC.

发明人： Alexander Barnes BALDWIN ,  Yi-Kai LO

IPC分类号： A61B5/02 ,  A61B5/00

CPC分类号： A61B5/02042 ,  A61B5/0086 ,  A61B5/4222 ,  A61B5/6861 ,  A61B5/7225

摘要： Systems and methods that can employ a bleeding sensor that uses an optical mechanism to detect blood in the patients GI tract are described. The bleeding sensor includes a substrate holding a centrally-located light detector with a broad sensitivity spectrum and at least two light emitters positioned radially around the centrally-located light detector, each light emitter configured to emit light of different primary wavelengths. The bleeding sensor has a gap between each of the at least two light emitters and the centrally-located light detector that accepts the contents of a patients gastrointestinal tract. An optical cap covers the centrally-located light detector and the at least two light emitters to direct the light emitted from the at least two light emitters through the gap and onto the centrally-located light detector.

公开(公告)号：US20240074672A1

公开(公告)日：2024-03-07

申请号：US18260862

申请日：2022-01-28

申请人： Biograil APS

发明人： Nikolaj Skak ,  Karsten Lindhardt ,  Kamille Majken Dumong Erichsen

IPC分类号： A61B5/07 ,  A61B5/00 ,  A61M31/00

CPC分类号： A61B5/073 ,  A61B5/6861 ,  A61M31/002

摘要： A drug delivery device having an axis, the drug delivery device comprising a carrier and an insert, the carrier comprising a first body part having a first recess, a first attachment part attached to the first body part and having a first distal end, a second body part having a second recess an actuator mechanism configured to rotate at least one of the first body part or the second body part with respect to one another about the axis, and an insert configured to be inserted and fixed in the second recess, the insert comprising a second attachment part and an insert body with an insert recess, the second attachment part having a second distal end.

公开(公告)号：US20240049968A1

公开(公告)日：2024-02-15

申请号：US18492038

申请日：2023-10-23

申请人： Medtronic, Inc.

发明人： Alfonso Aranda Hernandez ,  Richard Cornelussen ,  Mirko de Melis ,  Richard Sutton ,  Berthold Stegemann

IPC分类号： A61B5/0205 ,  A61B5/07 ,  A61B5/00

CPC分类号： A61B5/0205 ,  A61B5/076 ,  A61B5/7282 ,  A61B5/6861 ,  A61B5/686 ,  A61N1/3756

摘要： In some examples, determining a heart failure status using a medical device comprising one or more sensors includes determining a first value of a heart beat variability metric of a patient while an activity state of a patient satisfies an inactivity criterion based on a signal received from the one or more sensors, and determining, within a predetermined period of time after further determining that the activity state of the patient no longer satisfies the inactivity criterion, a second value of the heart beat variability metric while the activity state of the patient no longer satisfies the inactivity criterion based on the signal. A difference between the first value of the heart beat variability metric and the second value of the heart beat variability metric may be determined and the heart failure status of the patient may be determined based on the difference.

公开(公告)号：US11890092B2

公开(公告)日：2024-02-06

申请号：US17252600

申请日：2019-06-14

申请人： OTSUKA PHARMACEUTICAL CO. LTD.

发明人： Robert Azevedo ,  Neraj P. Bobra ,  Aditya Dua ,  Ronny X. Li ,  William A. Weeks

IPC分类号： A61B5/11 ,  A61B5/00 ,  A61B5/07 ,  A61B5/318 ,  G01C22/00 ,  G16H20/30 ,  G16H40/67

CPC分类号： A61B5/1118 ,  A61B5/0002 ,  A61B5/073 ,  A61B5/318 ,  A61B5/6801 ,  A61B5/6861 ,  A61B5/725 ,  A61B5/7282 ,  G01C22/006 ,  G16H20/30 ,  G16H40/67 ,  A61B2562/0219

摘要： A system, a wearable device, and a method are provided which can increase the accuracy of physiological metrics while detecting if the patient ingested digital medicine and/or improve performance of the wearable device. The wearable device can comprise machine executable instructions that when executed by the processor, cause the processor to perform various algorithms, such as, for example, at least one of a step count algorithm, a body angle algorithm, a heart rate algorithm, a peak finder algorithm, an adaptive thresholding algorithm, a heart rate variability algorithm, a R-R cleaning Algorithm, a deltaR-R cleaning algorithm, a merge twin interval algorithm, a split tall intervals algorithm, an absorb short intervals algorithm, a bimodal detection algorithm, and a resting algorithm.