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公开(公告)号:US07422749B2
公开(公告)日:2008-09-09
申请号:US11698250
申请日:2007-01-25
申请人: Michael T. Black , Martin K. Burnham , Jason C. Fedon , John E. Hodgson , David J. Knowles , Michael A. Lonetto , Richard O. Nicholas , Leslie M. Palmer , Julie M. Pratt , Raymond W. Reichard , Martin Rosenberg , Christopher M. Traini , Judith Ward , Richard L. Warren
发明人: Michael T. Black , Martin K. Burnham , Jason C. Fedon , John E. Hodgson , David J. Knowles , Michael A. Lonetto , Richard O. Nicholas , Leslie M. Palmer , Julie M. Pratt , Raymond W. Reichard , Martin Rosenberg , Christopher M. Traini , Judith Ward , Richard L. Warren
CPC分类号: C12N9/0036 , A61K38/00 , A61K39/00 , C07K14/31 , C07K16/1275 , C07K2319/00 , C12N9/78 , C12N15/52 , C12Q1/689 , C12Q2600/158 , C12Y105/0103 , C12Y305/04025
摘要: This invention relates to newly identified Staphylococcal polynucleotides, polypeptides encoded by such polynucleotides, the uses of such polynucleotides and polypeptides, as well as the production of such polynucleotides and polypeptides and recombinant host cells transformed with the polynucleotides. This invention also relates to inhibiting the biosynthesis or action of such polynucleotides or polypeptides and to the use of such inhibitors in therapy.
摘要翻译: 本发明涉及新鉴定的葡萄球菌多核苷酸,由这种多核苷酸编码的多肽,这种多核苷酸和多肽的用途,以及这些多核苷酸和多肽的产生以及用多核苷酸转化的重组宿主细胞。 本发明还涉及抑制这些多核苷酸或多肽的生物合成或作用以及这种抑制剂在治疗中的用途。
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公开(公告)号:US5840560A
公开(公告)日:1998-11-24
申请号:US896083
申请日:1997-07-17
申请人: Michael Terence Black , John Edward Hodgson , David Justin Charles Knowles , Michael Arthur Lonetto , Richard O. Nicholas , Robert King Stodola , Martin Karl Russel Burnham
发明人: Michael Terence Black , John Edward Hodgson , David Justin Charles Knowles , Michael Arthur Lonetto , Richard O. Nicholas , Robert King Stodola , Martin Karl Russel Burnham
IPC分类号: A61K38/00 , A61K39/00 , C07K14/315 , C12N1/21 , C12N9/12 , C12N9/78 , C12N15/54 , C07H21/04 , C12N1/20 , C12N15/00
CPC分类号: C12N9/1205 , C07K14/3156 , C12N9/78 , C12Y207/01002 , A61K38/00 , A61K39/00
摘要: The invention provides Glucose Kinase polypeptides and DNA (RNA) encoding Glucose Kinase polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing Glucose Kinase polypeptides to screen for antibacterial compounds.
摘要翻译: 本发明提供了葡萄糖激酶多肽和编码葡萄糖激酶多肽的DNA(RNA)以及通过重组技术产生这种多肽的方法。 还提供了利用葡萄糖激酶多肽筛选抗菌化合物的方法。
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