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    Antiplasma animal model
    2.
    发明授权
    Antiplasma animal model 失效
    抗体动物模型

    公开(公告)号：US5804159A

    公开(公告)日：1998-09-08

    申请号：US663031

    申请日：1996-06-07

    申请人： Johann Eibl ,  Peter Turecek ,  Hans Peter Schwarz

    发明人： Johann Eibl ,  Peter Turecek ,  Hans Peter Schwarz

    IPC分类号： A61K38/00 ,  C07K16/36 ,  A61K48/00 ,  C07K16/00 ,  C12N15/63

    CPC分类号： C07K16/36 ,  A61K38/00

    摘要： There is disclosed an anti-plasma antibody preparation for treatment of a mammal, which preparation is capable of directly or indirectly inhibiting and/or eliminating several blood factors, a method of producing such a preparation and a method of evaluating substances for treating clotting disorders by using said anti-plasma antibody preparation. There is further disclosed a method of determining the bleeding characteristics of a mammal.

    摘要翻译： 公开了一种用于治疗哺乳动物的抗血浆抗体制剂，该制剂能够直接或间接地抑制和/或消除多种血液因子，制备这种制剂的方法和评估用于治疗凝血障碍的物质的方法通过 使用所述抗血浆抗体制剂。 还公开了确定哺乳动物的出血特征的方法。

    Stable preparation for the treatment of blood coagulation disorders
    4.
    发明授权
    Stable preparation for the treatment of blood coagulation disorders 失效
    稳定的治疗凝血障碍的准备

    公开(公告)号：US6017891A

    公开(公告)日：2000-01-25

    申请号：US924533

    申请日：1997-09-05

    申请人： Johann Eibl ,  Hans Peter Schwarz ,  Juergen Siekmann ,  Peter Turecek

    发明人： Johann Eibl ,  Hans Peter Schwarz ,  Juergen Siekmann ,  Peter Turecek

    IPC分类号： C12N9/64 ,  C12N9/96 ,  A61K38/00 ,  A01N57/26 ,  A61K9/127

    CPC分类号： B82Y5/00 ,  C12N9/6424 ,  C12N9/96

    摘要： The invention relates to a stable preparation which comprises a protein, such as thrombin, that is bound in and/or on (i.e., to) lipid vesicles and that was treated for the inactivation of potentially present viruses. Further, the invention relates to methods for the production of a stable preparation for the treatment of blood coagulation disorders, wherein a protein is bound in and/or on lipid vesicles, and the method comprises a step in which the protein lipid complex is subjected to a treatment for the inactivation of potentially present viruses.

    摘要翻译： 本发明涉及一种稳定的制剂，其包含结合于脂质囊泡中和/或上（即）脂质囊泡上的蛋白质，例如凝血酶，并且被处理用于灭活潜在的存在的病毒。 此外，本发明涉及生产用于治疗凝血障碍的稳定制剂的方法，其中蛋白质与脂质囊泡中和/或结合，该方法包括将蛋白质脂质复合物经受 用于灭活潜在存在的病毒的治疗。

    Devices and methods for removing pathogens from biological fluids
    9.
    发明授权
    Devices and methods for removing pathogens from biological fluids 有权
    用于从生物流体中除去病原体的装置和方法

    公开(公告)号：US06270672B1

    公开(公告)日：2001-08-07

    申请号：US09369692

    申请日：1999-08-06

    申请人： Peter Turecek ,  Erwin Mattes ,  Hans Peter Schwarz

    发明人： Peter Turecek ,  Erwin Mattes ,  Hans Peter Schwarz

    IPC分类号： B01D6114

    CPC分类号： B01D61/425 ,  A61L2/0011 ,  A61L2/0017 ,  B01D57/02

    摘要： A method for removing pathogens from biological liquids and an apparatus for performing such a method, said method comprising the steps of providing a biological liquid, wherein pathogens are potentially present, in an apparatus comprising an anode and a kathode and a separation means suitable for separating said pathogens from said pharmaceutically active molecule, said separation means being positioned between said anode and said kathode, applying current between said anode and said kathode, thereby causing one of said pathogens or said pharmaceutically active molecule to pass said separation means and recovering said pharmaceutically active molecule in a form being free of said pathogens as well as an apparatus carrying out the present method.

    摘要翻译： 一种用于从生物液体中除去病原体的方法和用于进行这种方法的装置，所述方法包括以下步骤：在包含阳极和阴极的设备中提供其中潜在存在病原体的生物液体，以及适于分离所述 来自所述药物活性分子的病原体，所述分离装置位于所述阳极和所述阴极之间，在所述阳极和所述阴极之间施加电流，从而使所述病原体或所述药物活性分子之一通过所述分离装置并将所述药物活性分子 没有所述病原体的形式以及实施本方法的装置。