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1.发明申请Method for Changing Surface Properties of a Substrate from Immobilized Biomolecules 有权从固定化生物分子改变底物表面性质的方法公开(公告)号：US20130210110A1
公开(公告)日：2013-08-15
申请号：US13437340
申请日：2012-04-02
申请人： Ming-Yu Lin , Yuh-Shyong Yang , Yen-Pei Lu , Chih-Heng Lin
发明人： Ming-Yu Lin , Yuh-Shyong Yang , Yen-Pei Lu , Chih-Heng Lin
IPC分类号： C12N11/16 , C07K14/195 , C07K14/00
CPC分类号： C12N11/14
摘要： A method that modifies surface properties of a substrate by manipulating the immobilized biomolecules in mild biological condition. The manipulation comprised steps of: providing a biomolecule combined with at least one ssDNA combined with a first protein through an affinity binding tag; adding a second ssDNA conjugated with a second protein with a concentration greater than that of the first protein; and replacing the first protein on the ssDNA with the second protein through chemical competitive principle. The invention may comprise the steps with proper design of biotinylated DNA probes, the functionalized ssDNA nanotemplates can be recovered to its unbound state through a thermodynamic principle.
摘要翻译： 通过在温和的生物学条件下操纵固定化的生物分子来修饰底物的表面性质的方法。 操作包括以下步骤：通过亲和结合标签提供与至少一种与第一蛋白质组合的ssDNA组合的生物分子; 加入与第二种蛋白质缀合的第二种ssDNA，其浓度大于第一种蛋白质的浓度; 并通过化学竞争原理用ssDNA替代第二个蛋白质上的第一个蛋白质。 本发明可以包括具有适当设计生物素化DNA探针的步骤，功能化的ssDNA纳米模板可以通过热力学原理回收到其未结合状态。
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2.发明授权Method for changing surface properties of a substrate from immobilized biomolecules 有权从固定化生物分子改变底物表面性质的方法公开(公告)号：US08563245B2
公开(公告)日：2013-10-22
申请号：US13437340
申请日：2012-04-02
申请人： Ming-Yu Liu , Yuh-Shyong Yang , Yen-Pei Lu , Chih-Heng Lin
发明人： Ming-Yu Liu , Yuh-Shyong Yang , Yen-Pei Lu , Chih-Heng Lin
CPC分类号： C12N11/14
摘要： A method that modifies surface properties of a substrate by manipulating the immobilized biomolecules in mild biological condition. The manipulation comprised steps of: providing a biomolecule combined with at least one ssDNA combined with a first protein through an affinity binding tag; adding a second ssDNA conjugated with a second protein with a concentration greater than that of the first protein; and replacing the first protein on the ssDNA with the second protein through chemical competitive principle. The invention may comprise the steps with proper design of biotinylated DNA probes, the functionalized ssDNA nanotemplates can be recovered to its unbound state through a thermodynamic principle.
摘要翻译： 通过在温和的生物学条件下操纵固定化的生物分子来修饰底物的表面性质的方法。 操作包括以下步骤：通过亲和结合标签提供与至少一种与第一蛋白质组合的ssDNA组合的生物分子; 加入与第二种蛋白质缀合的第二种ssDNA，其浓度大于第一种蛋白质的浓度; 并通过化学竞争原理用ssDNA替代第二个蛋白质上的第一个蛋白质。 本发明可以包括具有适当设计生物素化DNA探针的步骤，功能化的ssDNA纳米模板可以通过热力学原理回收到其未结合状态。
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公开(公告)号：US20090137947A1
公开(公告)日：2009-05-28
申请号：US12291876
申请日：2008-11-14
申请人： Yuh-Shyong Yang , Ming-Yu Lin , Kuei-Shin Tsai , Wen-Ying Chang , Chih-Heng Lin , Jo-Fen Wei
发明人： Yuh-Shyong Yang , Ming-Yu Lin , Kuei-Shin Tsai , Wen-Ying Chang , Chih-Heng Lin , Jo-Fen Wei
IPC分类号： A61M5/00
CPC分类号： A61B5/4839 , A61B5/0002 , A61B5/0006 , A61B5/021 , A61B5/02438 , A61B5/0476 , A61B5/145 , A61B5/14532 , A61B5/1486 , A61B5/14865 , G06F19/00 , G06F19/3468
摘要： A system of a wireless physiological signal integration is provided. The system includes a wireless transmission sensor chip and a drug delivering system, wherein the wireless transmission sensor chip includes a sensor sensing a physiological signal of a patient, a signal conversion module converting the physiological signal into a converted signal, and a wireless transmission module wirelessly transmitting the converted signal, and the drug delivering system determines a dose of a drug and a timing for providing the drug according to the converted signal.
摘要翻译： 提供无线生理信号整合的系统。 该系统包括无线传输传感器芯片和药物递送系统，其中无线传输传感器芯片包括感测患者的生理信号的传感器，将生理信号转换为转换信号的信号转换模块以及无线传输模块 发送转换的信号，并且药物递送系统根据转换的信号确定药物的剂量和提供药物的定时。
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公开(公告)号：US08808229B2
公开(公告)日：2014-08-19
申请号：US12291876
申请日：2008-11-14
申请人： Yuh-Shyong Yang , Ming-Yu Lin , Kuei-Shin Tsai , Wen-Ying Chang , Chih-Heng Lin , Jo-Fen Wei
发明人： Yuh-Shyong Yang , Ming-Yu Lin , Kuei-Shin Tsai , Wen-Ying Chang , Chih-Heng Lin , Jo-Fen Wei
IPC分类号： A61M31/00 , A61B5/00 , G06F19/00 , A61B5/021 , A61B5/145 , A61B5/024 , A61B5/1486 , A61B5/0476
CPC分类号： A61B5/4839 , A61B5/0002 , A61B5/0006 , A61B5/021 , A61B5/02438 , A61B5/0476 , A61B5/145 , A61B5/14532 , A61B5/1486 , A61B5/14865 , G06F19/00 , G06F19/3468
摘要： A system of a wireless physiological signal integration is provided. The system includes a wireless transmission sensor chip and a drug delivering system, wherein the wireless transmission sensor chip includes a sensor sensing a physiological signal of a patient, a signal conversion module converting the physiological signal into a converted signal, and a wireless transmission module wirelessly transmitting the converted signal, and the drug delivering system determines a dose of a drug and a timing for providing the drug according to the converted signal.
摘要翻译： 提供无线生理信号整合的系统。 该系统包括无线传输传感器芯片和药物递送系统，其中无线传输传感器芯片包括感测患者的生理信号的传感器，将生理信号转换为转换信号的信号转换模块以及无线传输模块 发送转换的信号，并且药物递送系统根据转换的信号确定药物的剂量和提供药物的定时。
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公开(公告)号：US20210280973A1
公开(公告)日：2021-09-09
申请号：US16995784
申请日：2020-08-17
申请人： Chun-Cheng Chan , Shih-Chia Liu , Yen-Hao Yu , Li-Chun Lee , Chao-Lin Wu , Jui-Hung Lai , Chih-Heng Lin
发明人： Chun-Cheng Chan , Shih-Chia Liu , Yen-Hao Yu , Li-Chun Lee , Chao-Lin Wu , Jui-Hung Lai , Chih-Heng Lin
摘要： The disclosure provides an antenna structure, including at least one supporting module, a first antenna, and a second antenna. The first antenna is disposed on the at least one supporting module and includes a first feeding point and a first zero-current zone. The first antenna is connected to a ground plane. The second antenna is disposed on the at least one supporting module and includes a second feeding point and a second zero-current zone. The second antenna is connected to the ground plane. The first feeding point of the first antenna is disposed in the second zero-current zone of the second antenna, and the second feeding point of the second antenna is disposed in the first zero-current zone of the first antenna.
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公开(公告)号：US20220223996A1
公开(公告)日：2022-07-14
申请号：US17506687
申请日：2021-10-21
申请人： Jhih-Ciang Chen , Shih-Chia Liu , Yen-Hao Yu , Li-Chun Lee , Chih-Heng Lin , Je-Wei Liao , Chun-Cheng Chan , Jui-Hung Lai
发明人： Jhih-Ciang Chen , Shih-Chia Liu , Yen-Hao Yu , Li-Chun Lee , Chih-Heng Lin , Je-Wei Liao , Chun-Cheng Chan , Jui-Hung Lai
摘要： An electronic device including a first body, a second body, and at least one cavity antenna module is provided. The second body has a pivot side and a plurality of non-pivot sides, and the pivot side is connected pivotally to the first body. The cavity antenna module includes a metal cavity body and a first antenna structure. The metal cavity body is disposed in the second body and has an opening. A distance between one of the non-pivot sides and the metal cavity body is smaller than a distance between the pivot side and the metal cavity body, and the opening faces the one of the non-pivot sides. The first antenna structure is disposed in the opening of the metal cavity body, and the first antenna structure includes a feeding portion, a radiating portion, and a ground portion connected with one another.
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公开(公告)号：US11588244B2
公开(公告)日：2023-02-21
申请号：US16995784
申请日：2020-08-17
申请人： Chun-Cheng Chan , Shih-Chia Liu , Yen-Hao Yu , Li-Chun Lee , Chao-Lin Wu , Jui-Hung Lai , Chih-Heng Lin
发明人： Chun-Cheng Chan , Shih-Chia Liu , Yen-Hao Yu , Li-Chun Lee , Chao-Lin Wu , Jui-Hung Lai , Chih-Heng Lin
摘要： The disclosure provides an antenna structure, including at least one supporting module, a first antenna, and a second antenna. The first antenna is disposed on the at least one supporting module and includes a first feeding point and a first zero-current zone. The first antenna is connected to a ground plane. The second antenna is disposed on the at least one supporting module and includes a second feeding point and a second zero-current zone. The second antenna is connected to the ground plane. The first feeding point of the first antenna is disposed in the second zero-current zone of the second antenna, and the second feeding point of the second antenna is disposed in the first zero-current zone of the first antenna.
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公开(公告)号：US20210344119A1
公开(公告)日：2021-11-04
申请号：US17374954
申请日：2021-07-13
申请人： Chun-Cheng Chan , Shih-Chia Liu , Yen-Hao Yu , Li-Chun Lee , Jui-Hung Lai , Chih-Heng Lin
发明人： Chun-Cheng Chan , Shih-Chia Liu , Yen-Hao Yu , Li-Chun Lee , Jui-Hung Lai , Chih-Heng Lin
摘要： The disclosure provides an antenna structure including a ground plane, a first coupling antenna and a reference antenna. The first coupling antenna includes a first excitation source connected to the ground plane. The first excitation source is configured to excite a first resonant mode, and the first coupling antenna forms a first zero current area on the ground plane in response to the first resonant mode. The reference antenna includes a second excitation source connected to the ground plane. The second excitation source is configured to excite a second resonant mode, and the reference antenna forms a second zero current area on the ground plane in response to the second resonant mode. The first excitation source is located in the second zero current area, and the second excitation source is located in the first zero current area.
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