公开(公告)号：US11630079B2

公开(公告)日：2023-04-18

申请号：US17207653

申请日：2021-03-20

申请人： Mohammad Abdolahad ,  Zohreh Sadat Miripour ,  Hassan Sanati koloukhi ,  Fatemeh Zahra Shojaeian Zanjani ,  Hadi Ghafari ,  Naser Namdar Habashi ,  Ashkan Zandi ,  Fereshteh Abbasvandi

发明人： Mohammad Abdolahad ,  Zohreh Sadat Miripour ,  Hassan Sanati koloukhi ,  Fatemeh Zahra Shojaeian Zanjani ,  Hadi Ghafari ,  Naser Namdar Habashi ,  Ashkan Zandi ,  Fereshteh Abbasvandi

IPC分类号： G01N33/487 ,  G01N27/327 ,  G01N27/48 ,  A61B10/00

摘要： A method for diagnosing COVID-19 infection of a person. The method includes acquiring a sputum sample of the person, measuring a level of reactive oxygen species (ROS) in the sputum sample, and detecting a COVID-19 infection status of the person based on the measured level of ROS. Measuring the level of ROS in the sputum sample includes recording a cyclic voltammetry (CV) pattern from the sputum sample and measuring a current peak of the recorded CV pattern. Detecting the COVID-19 infection status of the person based on the measured level of ROS includes detecting the person is infected with COVID-19 if the measured current peak is in a first range of current peaks and detecting the person is not infected with COVID-19 if the measured current peak is in a second range of current peaks.

公开(公告)号：US11911628B2

公开(公告)日：2024-02-27

申请号：US17026238

申请日：2020-09-20

申请人： Mohammad Abdolahad ,  Ashkan Zandi

发明人： Mohammad Abdolahad ,  Ashkan Zandi

IPC分类号： A61N1/40 ,  A61N1/30 ,  A61N1/36 ,  A61K31/704 ,  A61K33/243 ,  A61K9/00 ,  A61K9/107 ,  A61N1/05 ,  A61N1/10 ,  B82Y5/00

CPC分类号： A61N1/40 ,  A61K9/0009 ,  A61K9/1075 ,  A61K31/704 ,  A61K33/243 ,  A61N1/0502 ,  A61N1/10 ,  A61N1/306 ,  A61N1/36002 ,  A61K9/0019 ,  B82Y5/00

摘要： A method for targeted drug delivery. The method includes injecting a drug composition into a cancer patient's body including forming an ion of an anticancer agent of the drug composition in bloodstream of the cancer patient, placing an electrically conductive element in a region next to a tumor location inside the cancer patient's body, and delivering the drug composition to the tumor location. Delivering the drug composition to the tumor location includes electrostatically trapping the drug composition within the tumor location by applying an electrostatic field with an opposite sign of electric charge to a sign of electric charge of the ion of the anticancer agent to the electrically conductive element.

公开(公告)号：US20220192583A1

公开(公告)日：2022-06-23

申请号：US17568335

申请日：2022-01-04

申请人： Mohammad Abdolahad ,  Ashkan Zandi ,  Amir Mamdouh ,  Alireza Madannejad ,  Yasin Kordehlachin ,  Seyed Mohammad Sadegh Mousavi-Kiasary ,  Fereshteh Abbasvandi

发明人： Mohammad Abdolahad ,  Ashkan Zandi ,  Amir Mamdouh ,  Alireza Madannejad ,  Yasin Kordehlachin ,  Seyed Mohammad Sadegh Mousavi-Kiasary ,  Fereshteh Abbasvandi

IPC分类号： A61B5/00 ,  A61B5/0507 ,  C12Q1/6886

摘要： A method for detecting sentinel lymph nodes during surgery. The method includes injecting a crystalloid solution into a region, measuring a plurality of electrical parameters utilizing a sensor, and detecting a sentinel lymph node among a plurality of lymph nodes based on the plurality of electrical parameters. The region is associated with a tumor in a patient's body. Measuring the plurality of electrical parameters includes measuring each respective electrical parameter of a respective lymph node of the plurality of lymph nodes. The plurality of lymph nodes are associated with the tumor. The sentinel lymph node is located at a shortest distance from the tumor among the plurality of lymph nodes.

公开(公告)号：US20210231638A1

公开(公告)日：2021-07-29

申请号：US17207653

申请日：2021-03-20

申请人： Mohammad Abdolahad ,  Zohreh Sadat Miripour ,  Hassan Sanati koloukhi ,  Fatemeh Zahra Shojaeian Zanjani ,  Hadi Ghafari ,  Naser Namdar Habashi ,  Ashkan Zandi ,  Fereshteh Abbasvandi

发明人： Mohammad Abdolahad ,  Zohreh Sadat Miripour ,  Hassan Sanati koloukhi ,  Fatemeh Zahra Shojaeian Zanjani ,  Hadi Ghafari ,  Naser Namdar Habashi ,  Ashkan Zandi ,  Fereshteh Abbasvandi

IPC分类号： G01N33/487 ,  G01N27/48 ,  G01N27/327

摘要： A method for diagnosing COVID-19 infection of a person. The method includes acquiring a sputum sample of the person, measuring a level of reactive oxygen species (ROS) in the sputum sample, and detecting a COVID-19 infection status of the person based on the measured level of ROS. Measuring the level of ROS in the sputum sample includes recording a cyclic voltammetry (CV) pattern from the sputum sample and measuring a current peak of the recorded CV pattern. Detecting the COVID-19 infection status of the person based on the measured level of ROS includes detecting the person is infected with COVID-19 if the measured current peak is in a first range of current peaks and detecting the person is not infected with COVID-19 if the measured current peak is in a second range of current peaks.

公开(公告)号：US20210001138A1

公开(公告)日：2021-01-07

申请号：US17026243

申请日：2020-09-20

申请人： Mohammad Abdolahad ,  Ashkan Zandi ,  Seyyed Hossein Miraghaie ,  Farid Abedin Dorkoosh ,  Zahra Davari-Shamsabadi

发明人： Mohammad Abdolahad ,  Ashkan Zandi ,  Seyyed Hossein Miraghaie ,  Farid Abedin Dorkoosh ,  Zahra Davari-Shamsabadi

IPC分类号： A61N1/40 ,  A61N1/30 ,  A61N1/36 ,  A61K33/243 ,  A61K31/704

摘要： A method for targeted drug delivery. The method includes preparing a drug composition with a surface electric charge, injecting the drug composition into a cancer patient's body, placing an electrically conductive element in a region next to a tumor location inside the cancer patient's body, and delivering the drug composition to the tumor location. Delivering the drug composition to the tumor location includes electrostatically trapping the drug composition within the tumor location by applying an electrostatic field with an opposite sign of electric charge to a sign of the surface electric charge of the drug composition to the electrically conductive element.

公开(公告)号：US20200049641A1

公开(公告)日：2020-02-13

申请号：US16654174

申请日：2019-10-16

申请人： Mohammad Abdolahad ,  Ashkan Zandi

发明人： Mohammad Abdolahad ,  Ashkan Zandi

IPC分类号： G01N27/02 ,  G01N33/487 ,  G01R27/22 ,  G01R31/28

摘要： A method for detecting cancerous status of a biological sample. The method includes calculating a charge transfer resistance (Rct) of an electrochemical impedance spectroscopy (EIS) associated with lipid secretion of a biological sample, detecting a cancerous state for the biological sample responsive to the calculated Rct being equal to or more than a threshold value, and detecting a normal state for the biological sample responsive to the calculated Rct being less than the threshold value. The biological sample includes a biological sample suspected to be cancerous.

公开(公告)号：US20190001151A1

公开(公告)日：2019-01-03

申请号：US16027315

申请日：2018-07-04

申请人： Mohammad Abdolahad ,  Saeed Rafizadeh Tafti ,  Ashkan Zandi

发明人： Mohammad Abdolahad ,  Saeed Rafizadeh Tafti ,  Ashkan Zandi

IPC分类号： A61N5/10

CPC分类号： A61N5/10 ,  A61N2005/1087 ,  B82Y15/00 ,  B82Y30/00 ,  C12Q2600/158 ,  G01N33/57415 ,  G01N33/57434 ,  G21K1/10

摘要： A method for tumor suppression is disclosed. The method includes preparing a chip by forming a layer of electrically conductive nanostructures on a substrate, placing the chip adjacent to a cancerous tumor, positively charging the layer of electrically conductive nanostructures by applying a positive electrostatic voltage on the chip, and reducing size of the cancerous tumor by electrostatically stimulating cancer cells of the cancerous tumor responsive to accumulating positive charges on the layer of electrically conductive nanostructures.

公开(公告)号：US11844955B2

公开(公告)日：2023-12-19

申请号：US17026243

申请日：2020-09-20

申请人： Mohammad Abdolahad ,  Ashkan Zandi ,  Seyyed Hossein Miraghaie ,  Farid Abedin dorkoosh ,  Zahra Davari-shamsabadi

发明人： Mohammad Abdolahad ,  Ashkan Zandi ,  Seyyed Hossein Miraghaie ,  Farid Abedin dorkoosh ,  Zahra Davari-shamsabadi

IPC分类号： A61N1/40 ,  A61N1/30 ,  A61N1/36 ,  A61K31/704 ,  A61K33/243 ,  A61K9/00 ,  A61K9/107 ,  A61N1/05 ,  A61N1/10 ,  B82Y5/00

CPC分类号： A61N1/40 ,  A61K9/0009 ,  A61K9/1075 ,  A61K31/704 ,  A61K33/243 ,  A61N1/0502 ,  A61N1/10 ,  A61N1/306 ,  A61N1/36002 ,  A61K9/0019 ,  B82Y5/00

摘要： A method for targeted drug delivery. The method includes preparing a drug composition with a surface electric charge, injecting the drug composition into a cancer patient's body, placing an electrically conductive element in a region next to a tumor location inside the cancer patient's body, and delivering the drug composition to the tumor location. Delivering the drug composition to the tumor location includes electrostatically trapping the drug composition within the tumor location by applying an electrostatic field with an opposite sign of electric charge to a sign of the surface electric charge of the drug composition to the electrically conductive element.

公开(公告)号：US20210022800A1

公开(公告)日：2021-01-28

申请号：US17063689

申请日：2020-10-05

申请人： Mohammad Abdolahad ,  Ashkan Zandi ,  Yasin Kordehlachin ,  Sahar Najafikhoshnoo ,  Ali Gilani ,  Fatemeh Zahra Shojaeian Zanjani ,  Seyed Mohamad Sadegh Mousavi Kiasary

发明人： Mohammad Abdolahad ,  Ashkan Zandi ,  Yasin Kordehlachin ,  Sahar Najafikhoshnoo ,  Ali Gilani ,  Fatemeh Zahra Shojaeian Zanjani ,  Seyed Mohamad Sadegh Mousavi Kiasary

IPC分类号： A61B18/14 ,  A61B18/12 ,  A61B90/00 ,  A61B34/30

摘要： A method for tumor suppression. The method includes inserting an active part of a wire into a cancerous tumor, electrostatically stimulating cancer cells of the cancerous tumor by injecting positive electrostatic charges to the cancer cells, and reducing size of the cancerous tumor responsive to the electrostatically stimulating cancer cells of the cancerous tumor. The active part of the wire is located at a first end of the wire. Injecting the positive electrostatic charges to the cancer cells includes accumulating the positive electrostatic charges on the inserted active part of the wire, and generating a positive electrostatic charge flow through the cancerous tumor responsive to accumulating the positive electrostatic charges on the inserted active part of the wire.

公开(公告)号：US20210001118A1

公开(公告)日：2021-01-07

申请号：US17026238

申请日：2020-09-20

申请人： Mohammad Abdolahad ,  Ashkan Zandi

发明人： Mohammad Abdolahad ,  Ashkan Zandi

IPC分类号： A61N1/10 ,  A61N1/05 ,  A61K33/243 ,  A61K31/704 ,  A61K9/107 ,  A61K9/00

摘要： A method for targeted drug delivery. The method includes injecting a drug composition into a cancer patient's body including forming an ion of an anticancer agent of the drug composition in bloodstream of the cancer patient, placing an electrically conductive element in a region next to a tumor location inside the cancer patient's body, and delivering the drug composition to the tumor location. Delivering the drug composition to the tumor location includes electrostatically trapping the drug composition within the tumor location by applying an electrostatic field with an opposite sign of electric charge to a sign of electric charge of the ion of the anticancer agent to the electrically conductive element.