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公开(公告)号：US11630079B2
公开(公告)日：2023-04-18
申请号：US17207653
申请日：2021-03-20
申请人： Mohammad Abdolahad , Zohreh Sadat Miripour , Hassan Sanati koloukhi , Fatemeh Zahra Shojaeian Zanjani , Hadi Ghafari , Naser Namdar Habashi , Ashkan Zandi , Fereshteh Abbasvandi
发明人： Mohammad Abdolahad , Zohreh Sadat Miripour , Hassan Sanati koloukhi , Fatemeh Zahra Shojaeian Zanjani , Hadi Ghafari , Naser Namdar Habashi , Ashkan Zandi , Fereshteh Abbasvandi
IPC分类号： G01N33/487 , G01N27/327 , G01N27/48 , A61B10/00
摘要： A method for diagnosing COVID-19 infection of a person. The method includes acquiring a sputum sample of the person, measuring a level of reactive oxygen species (ROS) in the sputum sample, and detecting a COVID-19 infection status of the person based on the measured level of ROS. Measuring the level of ROS in the sputum sample includes recording a cyclic voltammetry (CV) pattern from the sputum sample and measuring a current peak of the recorded CV pattern. Detecting the COVID-19 infection status of the person based on the measured level of ROS includes detecting the person is infected with COVID-19 if the measured current peak is in a first range of current peaks and detecting the person is not infected with COVID-19 if the measured current peak is in a second range of current peaks.
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公开(公告)号：US11844955B2
公开(公告)日：2023-12-19
申请号：US17026243
申请日：2020-09-20
申请人： Mohammad Abdolahad , Ashkan Zandi , Seyyed Hossein Miraghaie , Farid Abedin dorkoosh , Zahra Davari-shamsabadi
发明人： Mohammad Abdolahad , Ashkan Zandi , Seyyed Hossein Miraghaie , Farid Abedin dorkoosh , Zahra Davari-shamsabadi
IPC分类号： A61N1/40 , A61N1/30 , A61N1/36 , A61K31/704 , A61K33/243 , A61K9/00 , A61K9/107 , A61N1/05 , A61N1/10 , B82Y5/00
CPC分类号： A61N1/40 , A61K9/0009 , A61K9/1075 , A61K31/704 , A61K33/243 , A61N1/0502 , A61N1/10 , A61N1/306 , A61N1/36002 , A61K9/0019 , B82Y5/00
摘要： A method for targeted drug delivery. The method includes preparing a drug composition with a surface electric charge, injecting the drug composition into a cancer patient's body, placing an electrically conductive element in a region next to a tumor location inside the cancer patient's body, and delivering the drug composition to the tumor location. Delivering the drug composition to the tumor location includes electrostatically trapping the drug composition within the tumor location by applying an electrostatic field with an opposite sign of electric charge to a sign of the surface electric charge of the drug composition to the electrically conductive element.
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公开(公告)号：US20210022800A1
公开(公告)日：2021-01-28
申请号：US17063689
申请日：2020-10-05
申请人： Mohammad Abdolahad , Ashkan Zandi , Yasin Kordehlachin , Sahar Najafikhoshnoo , Ali Gilani , Fatemeh Zahra Shojaeian Zanjani , Seyed Mohamad Sadegh Mousavi Kiasary
发明人： Mohammad Abdolahad , Ashkan Zandi , Yasin Kordehlachin , Sahar Najafikhoshnoo , Ali Gilani , Fatemeh Zahra Shojaeian Zanjani , Seyed Mohamad Sadegh Mousavi Kiasary
摘要： A method for tumor suppression. The method includes inserting an active part of a wire into a cancerous tumor, electrostatically stimulating cancer cells of the cancerous tumor by injecting positive electrostatic charges to the cancer cells, and reducing size of the cancerous tumor responsive to the electrostatically stimulating cancer cells of the cancerous tumor. The active part of the wire is located at a first end of the wire. Injecting the positive electrostatic charges to the cancer cells includes accumulating the positive electrostatic charges on the inserted active part of the wire, and generating a positive electrostatic charge flow through the cancerous tumor responsive to accumulating the positive electrostatic charges on the inserted active part of the wire.
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公开(公告)号：US20210001118A1
公开(公告)日：2021-01-07
申请号：US17026238
申请日：2020-09-20
申请人： Mohammad Abdolahad , Ashkan Zandi
发明人： Mohammad Abdolahad , Ashkan Zandi
IPC分类号： A61N1/10 , A61N1/05 , A61K33/243 , A61K31/704 , A61K9/107 , A61K9/00
摘要： A method for targeted drug delivery. The method includes injecting a drug composition into a cancer patient's body including forming an ion of an anticancer agent of the drug composition in bloodstream of the cancer patient, placing an electrically conductive element in a region next to a tumor location inside the cancer patient's body, and delivering the drug composition to the tumor location. Delivering the drug composition to the tumor location includes electrostatically trapping the drug composition within the tumor location by applying an electrostatic field with an opposite sign of electric charge to a sign of electric charge of the ion of the anticancer agent to the electrically conductive element.
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公开(公告)号：US20180251901A1
公开(公告)日：2018-09-06
申请号：US15960524
申请日：2018-04-23
IPC分类号： C25B1/02 , C25B9/06 , C25B11/04 , C23C14/20 , C23C14/34 , C23C14/58 , C23C14/00 , G01N27/48 , A61B5/1473 , G01N33/49
CPC分类号： G01N27/48 , A61B5/1473 , C23C14/0005 , C23C14/022 , C23C14/205 , C23C14/3464 , C23C14/5806 , C23C14/5846 , C25B1/02 , C25B9/06 , C25B11/0405 , C25B11/0415 , C25B11/0478 , G01N27/327 , G01N33/4833 , G01N33/49 , G03F7/70
摘要： A method for in-situ generation of microbubbles is disclosed. The method includes preparing an electrochemical apparatus, where the electrochemical apparatus includes a substrate and an integrated three-electrodes array patterned on the substrate. The integrated three-electrodes array includes a working electrode, a reference electrode, and a counter electrode. The method further includes growing a nano-structured layer on the working electrode of the integrated three-electrodes array, putting the electrochemical apparatus in contact with a medium fluid, electrolyzing the medium fluid by applying an instantaneous electrical potential to the electrochemical apparatus, and generating a plurality of microbubbles around the electrochemical apparatus in contact with the medium fluid responsive to electrolyzing of the medium fluid.
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公开(公告)号：US20210231638A1
公开(公告)日：2021-07-29
申请号：US17207653
申请日：2021-03-20
申请人： Mohammad Abdolahad , Zohreh Sadat Miripour , Hassan Sanati koloukhi , Fatemeh Zahra Shojaeian Zanjani , Hadi Ghafari , Naser Namdar Habashi , Ashkan Zandi , Fereshteh Abbasvandi
发明人： Mohammad Abdolahad , Zohreh Sadat Miripour , Hassan Sanati koloukhi , Fatemeh Zahra Shojaeian Zanjani , Hadi Ghafari , Naser Namdar Habashi , Ashkan Zandi , Fereshteh Abbasvandi
IPC分类号： G01N33/487 , G01N27/48 , G01N27/327
摘要： A method for diagnosing COVID-19 infection of a person. The method includes acquiring a sputum sample of the person, measuring a level of reactive oxygen species (ROS) in the sputum sample, and detecting a COVID-19 infection status of the person based on the measured level of ROS. Measuring the level of ROS in the sputum sample includes recording a cyclic voltammetry (CV) pattern from the sputum sample and measuring a current peak of the recorded CV pattern. Detecting the COVID-19 infection status of the person based on the measured level of ROS includes detecting the person is infected with COVID-19 if the measured current peak is in a first range of current peaks and detecting the person is not infected with COVID-19 if the measured current peak is in a second range of current peaks.
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公开(公告)号：US20210001138A1
公开(公告)日：2021-01-07
申请号：US17026243
申请日：2020-09-20
申请人： Mohammad Abdolahad , Ashkan Zandi , Seyyed Hossein Miraghaie , Farid Abedin Dorkoosh , Zahra Davari-Shamsabadi
发明人： Mohammad Abdolahad , Ashkan Zandi , Seyyed Hossein Miraghaie , Farid Abedin Dorkoosh , Zahra Davari-Shamsabadi
IPC分类号： A61N1/40 , A61N1/30 , A61N1/36 , A61K33/243 , A61K31/704
摘要： A method for targeted drug delivery. The method includes preparing a drug composition with a surface electric charge, injecting the drug composition into a cancer patient's body, placing an electrically conductive element in a region next to a tumor location inside the cancer patient's body, and delivering the drug composition to the tumor location. Delivering the drug composition to the tumor location includes electrostatically trapping the drug composition within the tumor location by applying an electrostatic field with an opposite sign of electric charge to a sign of the surface electric charge of the drug composition to the electrically conductive element.
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公开(公告)号：US20200049641A1
公开(公告)日：2020-02-13
申请号：US16654174
申请日：2019-10-16
申请人： Mohammad Abdolahad , Ashkan Zandi
发明人： Mohammad Abdolahad , Ashkan Zandi
IPC分类号： G01N27/02 , G01N33/487 , G01R27/22 , G01R31/28
摘要： A method for detecting cancerous status of a biological sample. The method includes calculating a charge transfer resistance (Rct) of an electrochemical impedance spectroscopy (EIS) associated with lipid secretion of a biological sample, detecting a cancerous state for the biological sample responsive to the calculated Rct being equal to or more than a threshold value, and detecting a normal state for the biological sample responsive to the calculated Rct being less than the threshold value. The biological sample includes a biological sample suspected to be cancerous.
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公开(公告)号：US20190001151A1
公开(公告)日：2019-01-03
申请号：US16027315
申请日：2018-07-04
IPC分类号： A61N5/10
CPC分类号： A61N5/10 , A61N2005/1087 , B82Y15/00 , B82Y30/00 , C12Q2600/158 , G01N33/57415 , G01N33/57434 , G21K1/10
摘要： A method for tumor suppression is disclosed. The method includes preparing a chip by forming a layer of electrically conductive nanostructures on a substrate, placing the chip adjacent to a cancerous tumor, positively charging the layer of electrically conductive nanostructures by applying a positive electrostatic voltage on the chip, and reducing size of the cancerous tumor by electrostatically stimulating cancer cells of the cancerous tumor responsive to accumulating positive charges on the layer of electrically conductive nanostructures.
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公开(公告)号：US11911628B2
公开(公告)日：2024-02-27
申请号：US17026238
申请日：2020-09-20
申请人： Mohammad Abdolahad , Ashkan Zandi
发明人： Mohammad Abdolahad , Ashkan Zandi
IPC分类号： A61N1/40 , A61N1/30 , A61N1/36 , A61K31/704 , A61K33/243 , A61K9/00 , A61K9/107 , A61N1/05 , A61N1/10 , B82Y5/00
CPC分类号： A61N1/40 , A61K9/0009 , A61K9/1075 , A61K31/704 , A61K33/243 , A61N1/0502 , A61N1/10 , A61N1/306 , A61N1/36002 , A61K9/0019 , B82Y5/00
摘要： A method for targeted drug delivery. The method includes injecting a drug composition into a cancer patient's body including forming an ion of an anticancer agent of the drug composition in bloodstream of the cancer patient, placing an electrically conductive element in a region next to a tumor location inside the cancer patient's body, and delivering the drug composition to the tumor location. Delivering the drug composition to the tumor location includes electrostatically trapping the drug composition within the tumor location by applying an electrostatic field with an opposite sign of electric charge to a sign of electric charge of the ion of the anticancer agent to the electrically conductive element.
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