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公开(公告)号：US20200369733A1
公开(公告)日：2020-11-26
申请号：US16894459
申请日：2020-06-05
发明人： James A. BAUM , David J. BOWEN , Catherine A. CHAY , David J. CHI , William P. CLINTON , Crystal L. DART , Leigh ENGLISH , Stanislaw FLASINSKI , Victor M. GUZOV , Kevin A. JARRELL , Uma R. KESANAPALLI , Thomas M. MALVAR , Robert M. MCCARROLL , Jason S. MILLIGAN , Jay P. MORGENSTERN , Deborah G. RUCKER , Sara A. SALVADOR , Temple F. SMITH , Carlos E. SOTO , Collin M. STULTZ , Brian M. TURCZYK , Ty T. VAUGHN , Moritz W.F.F. VON RECHENBERG
IPC分类号： C07K14/325 , C12N15/82
摘要： Disclosed herein are nucleotide sequences encoding an insecticidal protein exhibiting Lepidopteran inhibitory activity, as well as novel insecticidal proteins referred to herein as a BCW 001, BCW 002, BCW 003, and BCW toxic protein-containing chimeras and BCW toxin insecticide, transgenic plants expressing the chimeras or the insecticide, and methods for detecting the presence of the nucleotide sequences or the insecticide in a biological sample.
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公开(公告)号：US20210100249A1
公开(公告)日：2021-04-08
申请号：US17127310
申请日：2020-12-18
发明人： James A. BAUM , Artem G. EVDOKIMOV , Farhad MOSHIRI , Timothy J. RYDEL , Eric J. STURMAN , Moritz von RECHENBERG , Halong VU , Andrew M. WOLLACOTT , Meiying ZHENG
IPC分类号： A01N63/10 , C12N15/82 , C07K14/00 , A01N37/46 , C07K14/435 , C07K14/325 , C07K14/32
摘要： The present invention discloses Hemipteran insect inhibitory proteins, methods of using such proteins, nucleotide sequences encoding such proteins, methods of detecting and isolating such proteins, and their use in agricultural systems.
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公开(公告)号：US20200277340A1
公开(公告)日：2020-09-03
申请号：US16874186
申请日：2020-05-14
发明人： James A. BAUM , Thomas A. CERRUTI , Crystal L. DART , Leigh H. ENGLISH , Stanislaw FLASINSKI , Xiaoran FU , Victor M. GUZOV , Arlene R. HOWE , Jay P. MORGENSTERN , James K. ROBERTS , Sara A. SALVADOR , Jinling WANG
IPC分类号： C07K14/325 , A01N63/10 , C12N15/82
摘要： Nucleotide sequences are disclosed that encode novel chimeric insecticidal proteins exhibiting Lepidopteran inhibitory activity. Particular embodiments provide compositions and transformed plants, plant parts, and seeds containing the recombinant nucleic acid molecules encoding one or more of the chimeric insecticidal proteins.
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4.发明申请公开(公告)号：US20180092364A1
公开(公告)日：2018-04-05
申请号：US15729114
申请日：2017-10-10
发明人： James A. BAUM , Allen T. CHRISTIAN , Artem EVDOKIMOV , Farhad MOSHIRI , Lisa Marie WEAVER , Haitao ZHANG
摘要： Compositions and methods for efficiently producing and delivering double stranded RNA (dsRNA) are provided. Vector constructs useful for in vitro and in vivo expression of dsRNA are described. Also described are cell expression systems for efficient and cost-effective production of dsRNA in living cells and methods and compositions for providing the expressed dsRNA to target organisms. The described compositions and methods can be used to produce RNA molecules for screening or other uses, and to amplify RNA sequences for analysis.
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5.发明公开公开(公告)号：US20230232838A1
公开(公告)日：2023-07-27
申请号：US18299295
申请日：2023-04-12
发明人： James A. BAUM , Allen T. CHRISTIAN , Artem EVDOKIMOV , Farhad MOSHIRI , Lisa Marie WEAVER , Haitao ZHANG
摘要： Compositions and methods for efficiently producing and delivering double stranded RNA (dsRNA) are provided. Vector constructs useful for in vitro and in vivo expression of dsRNA are described. Also described are cell expression systems for efficient and cost-effective production of dsRNA in living cells and methods and compositions for providing the expressed dsRNA to target organisms. The described compositions and methods can be used to produce RNA molecules for screening or other uses, and to amplify RNA sequences for analysis.
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公开(公告)号：US20170327547A1
公开(公告)日：2017-11-16
申请号：US15656616
申请日：2017-07-21
发明人： James A. BAUM , Thomas A. CERRUTI , Crystal L. DART , Leigh H. ENGLISH , Stanislaw FLASINSKI , Xiaoran FU , Victor M. GUZOV , Arlene R. HOWE , Jay P. MORGENSTERN , James K. ROBERTS , Sara A. SALVADOR , Jinling WANG
IPC分类号： C07K14/325 , C12N15/82 , A01N63/02
CPC分类号： C07K14/325 , A01N37/46 , A01N63/02 , C07K2319/00 , C12N15/62 , C12N15/8286 , Y02A40/162
摘要： Nucleotide sequences are disclosed that encode novel chimeric insecticidal proteins exhibiting Lepidopteran inhibitory activity. Particular embodiments provide compositions and transformed plants, plant parts, and seeds containing the recombinant nucleic acid molecules encoding one or more of the chimeric insecticidal proteins.
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公开(公告)号：US20170183683A1
公开(公告)日：2017-06-29
申请号：US15300661
申请日：2015-03-27
CPC分类号： C12N15/8286 , A01N57/16 , A01N63/02 , C12N15/8218 , C12N2310/14 , C12N2320/00 , Y02A40/162
摘要： Disclosed herein are methods of controlling insect pests which infest crop plants, in particular Spodoptera frugiperda (fall armyworm), Lygus hesperus (western tarnished plant bug), Euschistus heros (neotropical brown stink bug), and Plutella xylostella (diamondback moth), and methods of providing plants resistant to such pests. Also disclosed are polynucleotides and recombinant DNA molecules and constructs useful in such methods, insecticidal compositions such as topical sprays containing insecticidal double-stranded RNAs, and plants with improved resistance to infestation by these insects. Further disclosed are methods of selecting target genes for RNAi-mediated silencing and control of these insect pests.
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公开(公告)号：US20210010020A1
公开(公告)日：2021-01-14
申请号：US17028518
申请日：2020-09-22
发明人： James A. BAUM , Thomas Cerruti , Stanislaw Flasinski , Xiaoran Fu , Arlene R. Howe , Sara Ann Salvador
IPC分类号： C12N15/82 , C07K14/325 , A01N63/10 , A01N47/08
摘要： Engineered Cry1Da amino acid sequences are provided that exhibit improved Lepidopteran insecticidal activity and an enhanced Lepidopteran spectrum compared to the naturally occurring Cry1Da protein toxin. Polynucleotide sequences intended for use in expression of the improved proteins in plants are also provided. Particular embodiments provide compositions containing insect inhibitory amounts of the engineered proteins, as well as recombinant plants, plant parts, and seeds containing polynucleotide constructs encoding one or more of the improved engineered proteins.
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公开(公告)号：US20200040044A1
公开(公告)日：2020-02-06
申请号：US16658938
申请日：2019-10-21
发明人： James A. BAUM , Thomas A. CERRUTI , Crystal L. DART , Leigh H. ENGLISH , Stanislaw FLASINSKI , Xiaoran FU , Victor M. GUZOV , Arlene R. HOWE , Jay P. MORGENSTERN , James K. ROBERTS , Sara SALVADOR , Jinling Hung WANG
IPC分类号： C07K14/325 , A01N37/46 , A01N63/02 , C12N15/82
摘要： Nucleotide sequences are disclosed that encode novel chimeric insecticidal proteins exhibiting Lepidopteran inhibitory activity. Particular embodiments provide compositions and transformed plants, plant parts, and seeds containing the recombinant nucleic acid molecules encoding one or more of the chimeric insecticidal proteins.
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公开(公告)号：US20230348543A1
公开(公告)日：2023-11-02
申请号：US18319022
申请日：2023-05-17
发明人： James A. BAUM , David J. BOWEN , Catherine A. CHAY , David J. CHI , William P. CLINTON , Crystal L. DART , Leigh ENGLISH , Stanislaw FLASINSKI , Victor M. GUZOV , Kevin A. JARRELL , Uma R. KESANAPALLI , Thomas M. MALVAR , Robert M. MCCARROLL , Jason S. MILLIGAN , Jay P. MORGENSTERN , Deborah G. RUCKER , Sara A. SALVADOR , Temple F. SMITH , Carlos E. SOTO , Collin M. STULTZ , Brian M. TURCZYK , Ty T. VAUGHN , Moritz W.F. VON RECHENBERG
IPC分类号： C07K14/325 , A01N63/50 , C12N15/82
CPC分类号： C07K14/325 , A01N63/50 , C12N15/8286 , Y02A40/146
摘要： Disclosed herein are nucleotide sequences encoding an insecticidal protein exhibiting Lepidopteran inhibitory activity, as well as novel insecticidal proteins referred to herein as a BCW 001, BCW 002, BCW 003, and BCW toxic protein-containing chimeras and BCW toxin insecticide, transgenic plants expressing the chimeras or the insecticide, and methods for detecting the presence of the nucleotide sequences or the insecticide in a biological sample.
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