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公开(公告)号：US07841824B2
公开(公告)日：2010-11-30
申请号：US12454227
申请日：2009-05-14
IPC分类号： G01N33/497
CPC分类号： B01L3/0217 , B01L2200/0657 , B01L2300/0829 , B01L2400/043 , B03C1/0332 , B03C1/288 , B03C1/30 , B03C2201/18 , B03C2201/26 , G01N35/109 , G01N2035/0474
摘要： A control system for transferring a sample from a source vessel to a target vessel generally includes a vessel unit, a primary transfer unit, an x-drive, a y-drive, a z-drive and a control unit for controlling the drives. The vessel unit includes a support plate for supporting the source vessel and the target vessel thereon and the transfer unit includes at least one transfer device for transferring the sample from the source vessel to the target vessel. The x-, y- and z-drives reciprocally translate one of the support plate and the transfer device in a respective x-direction, y-direction and z-direction, wherein the x, y and z directions define a three axis Cartesian coordinate system.
摘要翻译： 用于将样品从源容器传送到目标容器的控制系统通常包括容器单元，一次传送单元，x驱动器，y驱动器，z驱动器和用于控制驱动器的控制单元。 容器单元包括用于在其上支撑源容器和目标容器的支撑板，并且转移单元包括用于将样品从源容器转移到目标容器的至少一个转移装置。 x，y和z驱动器在相应的x方向，y方向和z方向上将支撑板和传送装置中的一个相互平移，其中x，y和z方向限定三轴笛卡尔坐标 系统。
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公开(公告)号：US20090297327A1
公开(公告)日：2009-12-03
申请号：US12454227
申请日：2009-05-14
IPC分类号： B65G49/00
CPC分类号： B01L3/0217 , B01L2200/0657 , B01L2300/0829 , B01L2400/043 , B03C1/0332 , B03C1/288 , B03C1/30 , B03C2201/18 , B03C2201/26 , G01N35/109 , G01N2035/0474
摘要： A control system for transferring a sample from a source vessel to a target vessel generally includes a vessel unit, a primary transfer unit, an x-drive, a y-drive, a z-drive and a control unit for controlling the drives. The vessel unit includes a support plate for supporting the source vessel and the target vessel thereon and the transfer unit includes at least one transfer device for transferring the sample from the source vessel to the target vessel. The x-, y- and z-drives reciprocally translate one of the support plate and the transfer device in a respective x-direction, y-direction and z-direction, wherein the x, y and z directions define a three axis Cartesian coordinate system.
摘要翻译： 用于将样品从源容器传送到目标容器的控制系统通常包括容器单元，一次传送单元，x驱动器，y驱动器，z驱动器和用于控制驱动器的控制单元。 容器单元包括用于在其上支撑源容器和目标容器的支撑板，并且转移单元包括用于将样品从源容器转移到目标容器的至少一个转移装置。 x，y和z驱动器在相应的x方向，y方向和z方向上将支撑板和传送装置中的一个相互平移，其中x，y和z方向限定三轴笛卡尔坐标 系统。
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公开(公告)号：US07597520B2
公开(公告)日：2009-10-06
申请号：US11311558
申请日：2005-12-19
IPC分类号： G01N37/497
摘要： A transfer unit for transferring a sample from a source vessel to a target vessel. The transfer unit includes a transfer device having a pin tip with a central bore terminating at a bottom wall, an actuating element movably disposed in the pin tip bore, an actuator rod for moving the actuating element and a compensating device connected between the actuating element and the actuator rod. The actuator rod moves the actuating element between a first position adjacent the tip bottom wall and a second position away from the bottom wall. Movement of the actuating element causes a sample in proximity to the pin tip to be alternately collected and released from the pin tip. Such movement also defines a stroke length for the actuator rod, wherein the compensating device compensates for any variations in the actuator rod stroke length. The transfer unit further includes a tip ejector for removing the disposable tips from the transfer device and a tip loading station for applying the tips to the transfer device.
摘要翻译： 用于将样品从源容器转移到目标容器的转移单元。 传送单元包括具有销末端的传送装置，其中心孔终止在底壁处，可移动地设置在销尖孔中的致动元件，用于移动致动元件的致动杆和连接在致动元件和 执行器杆。 致动器杆将致动元件移动到与尖端底壁相邻的第一位置和远离底壁的第二位置之间。 致动元件的运动导致靠近销尖的样品交替地从销尖收集和释放。 这种运动还限定了致动器杆的行程长度，其中补偿装置补偿致动器杆行程长度中的任何变化。 传送单元还包括用于从传送装置移除一次性尖端的尖端喷射器和用于将尖端施加到传送装置的尖端装载站。
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4.发明申请Disposable vessels or tips having ultra-thin areas therein, and methods for manufacture of same 审中-公开具有超薄区域的一次性容器或尖端及其制造方法公开(公告)号：US20070172941A1
公开(公告)日：2007-07-26
申请号：US11338891
申请日：2006-01-25
申请人： Amir Porat , Moshe Gombinsky , Agmon Porat
发明人： Amir Porat , Moshe Gombinsky , Agmon Porat
IPC分类号： C12M3/00
CPC分类号： B01L3/508 , B01L3/5082 , B01L3/5085 , B01L2300/0829 , B01L2300/0851
摘要： The invention discloses disposable polymeric vessels or tip products, having a thin area upon at least a portion of the vessel or tip, for use in medical and scientific laboratories. The thin area has a thickness of less than 100 microns. Examples of such products are test-tubes, microtubes and multiwell plates. The thin area is transparent, and is advantageous for performance of optical assays, and in performance of attraction and transfer of magnetic particles. Methods for manufacturing the polymeric vessel and tip products are disclosed.
摘要翻译： 本发明公开了一种在医疗和科学实验室中使用的在容器或尖端的至少一部分上具有薄区域的一次性聚合物容器或尖端产品。 薄区域的厚度小于100微米。 这些产品的实例是试管，微管和多孔板。 薄区域是透明的，并且对于光学测定的性能以及磁性颗粒的吸引和转移的性能是有利的。 公开了制造聚合物容器和尖端产品的方法。
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公开(公告)号：US20060144169A1
公开(公告)日：2006-07-06
申请号：US11029013
申请日：2005-01-05
申请人： Amir Porat , Moshe Gombinsky
发明人： Amir Porat , Moshe Gombinsky
IPC分类号： G01N1/14
CPC分类号： B01L3/0217 , B01L3/021 , B01L2200/0657 , Y10T436/2575
摘要： A combinatorial pipettor device for the collection of a sample adapted for use with different size microtiter plates. The device comprises an upper plate having first and second halves, each half independently movable between an upper and a lower position, and a lower plate having tip connectors for the attachment of collecting tips. Also included are sample collector members having proximal ends and distal ends and a mechanism for moving at least one half of the upper plate between the upper and lower positions. Proximal ends of the sample collector members are held by the upper plate and distal ends of the sample collector members are engagable with the lower plate such that when at least one half of the upper plate is moved from the upper to the lower position, the corresponding sample collector members are lowered, thereby facilitating collection of a sample into a tip attached to one of the connectors.
摘要翻译： 用于收集适于与不同尺寸微量滴定板一起使用的样品的组合移液器装置。 该装置包括具有第一和第二半部的上板，每个半部可独立地在上部和下部位置之间移动，下部板具有用于附接收集尖端的尖端连接器。 还包括具有近端和远端的样本收集器构件和用于在上位置和下位置之间移动上板的至少一半的机构。 样品收集器构件的近端由上板保持，并且样品收集器构件的远端可与下板接合，使得当上板的至少一半从上位移到下位时，相应的 样品收集器构件被降低，从而便于将样品收集到连接到一个连接器的尖端中。
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公开(公告)号：US07534081B2
公开(公告)日：2009-05-19
申请号：US11135962
申请日：2005-05-24
IPC分类号： G01N33/497
CPC分类号： B01L3/0217 , B01L2200/0657 , B01L2300/0829 , B01L2400/043 , B03C1/0332 , B03C1/288 , B03C1/30 , B03C2201/18 , B03C2201/26 , G01N35/109 , G01N2035/0474
摘要： A control system for transferring a sample from a source vessel to a target vessel generally includes a vessel unit, a primary transfer unit, an x-drive, a y-drive, a z-drive and a control unit for controlling the drives. The vessel unit includes a support plate for supporting the source vessel and the target vessel thereon and the transfer unit includes at least one transfer device for transferring the sample from the source vessel to the target vessel. The x-, y- and z-drives reciprocally translate one of the support plate and the transfer device in a respective x-direction, y-direction and z-direction, wherein the x, y and z directions define a three axis Cartesian coordinate system.
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公开(公告)号：US07219567B2
公开(公告)日：2007-05-22
申请号：US11029013
申请日：2005-01-05
申请人： Amir Porat , Moshe Gombinsky
发明人： Amir Porat , Moshe Gombinsky
IPC分类号： G01N1/14
CPC分类号： B01L3/0217 , B01L3/021 , B01L2200/0657 , Y10T436/2575
摘要： A combinatorial pipettor device for the collection of a sample adapted for use with different size microtiter plates. The device comprises an upper plate having first and second halves, each half independently movable between an upper and a lower position, and a lower plate having tip connectors for the attachment of collecting tips. Also included are sample collector members having proximal ends and distal ends and a mechanism for moving at least one half of the upper plate between the upper and lower positions. Proximal ends of the sample collector members are held by the upper plate and distal ends of the sample collector members are engagable with the lower plate such that when at least one half of the upper plate is moved from the upper to the lower position, the corresponding sample collector members are lowered, thereby facilitating collection of a sample into a tip attached to one of the connectors.
摘要翻译： 用于收集适于与不同尺寸微量滴定板一起使用的样品的组合移液器装置。 该装置包括具有第一和第二半部的上板，每个半部可独立地在上部和下部位置之间移动，下部板具有用于附接收集尖端的尖端连接器。 还包括具有近端和远端的样本收集器构件和用于在上位置和下位置之间移动上板的至少一半的机构。 样品收集器构件的近端由上板保持，并且样品收集器构件的远端可与下板接合，使得当上板的至少一半从上位移到下位时，相应的 样品收集器构件被降低，从而便于将样品收集到连接到一个连接器的尖端中。
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公开(公告)号：US20060269385A1
公开(公告)日：2006-11-30
申请号：US11135962
申请日：2005-05-24
申请人： Hans-Jorg Zobel , Gerard Leeman , Amir Porat , Moshe Gombinsky
发明人： Hans-Jorg Zobel , Gerard Leeman , Amir Porat , Moshe Gombinsky
IPC分类号： B65B21/02
CPC分类号： B01L3/0217 , B01L2200/0657 , B01L2300/0829 , B01L2400/043 , B03C1/0332 , B03C1/288 , B03C1/30 , B03C2201/18 , B03C2201/26 , G01N35/109 , G01N2035/0474
摘要： A control system for transferring a sample from a source vessel to a target vessel generally includes a vessel unit, a primary transfer unit, an x-drive, a y-drive, a z-drive and a control unit for controlling the drives. The vessel unit includes a support plate for supporting the source vessel and the target vessel thereon and the transfer unit includes at least one transfer device for transferring the sample from the source vessel to the target vessel. The x-, y- and z-drives reciprocally translate one of the support plate and the transfer device in a respective x-direction, y-direction and z-direction, wherein the x, y and z directions define a three axis Cartesian coordinate system.
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公开(公告)号：US20060266130A1
公开(公告)日：2006-11-30
申请号：US11311558
申请日：2005-12-19
申请人： Hans-Jorg Zobel , Gerard Leeman , Amir Porat , Moshe Gombinsky
发明人： Hans-Jorg Zobel , Gerard Leeman , Amir Porat , Moshe Gombinsky
摘要： A transfer unit for transferring a sample from a source vessel to a target vessel. The transfer unit includes a transfer device having a pin tip with a central bore terminating at a bottom wall, an actuating element movably disposed in the pin tip bore, an actuator rod for moving the actuating element and a compensating device connected between the actuating element and the actuator rod. The actuator rod moves the actuating element between a first position adjacent the tip bottom wall and a second position away from the bottom wall. Movement of the actuating element causes a sample in proximity to the pin tip to be alternately collected and released from the pin tip. Such movement also defines a stroke length for the actuator rod, wherein the compensating device compensates for any variations in the actuator rod stroke length. The transfer unit further includes a tip ejector for removing the disposable tips from the transfer device and a tip loading station for applying the tips to the transfer device.
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公开(公告)号：US20060056993A1
公开(公告)日：2006-03-16
申请号：US11224947
申请日：2005-09-14
申请人： Moshe Gombinsky , Amir Porat
发明人： Moshe Gombinsky , Amir Porat
CPC分类号： F16F6/00 , F15B15/1476 , F16F2224/0216 , H01F7/0231 , H01F7/0242
摘要： A magnetic spring actuator comprising a ring, a piston movably disposed inside of the ring, and a-non-magnetic holding cylinder. At least one of the ring and the piston is magnetic. Due to a magnetic force caused by at least one of the ring and the piston, the piston is initially located in a first position with respect to the ring. Application of an outside force results in movement of the piston to a second position with respect to the ring. The magnetic force produces a return force for causing the piston to return to the first position with respect to the ring. Alternatively, the piston can be fixed and the ring can be adapted for moving with respect to the piston in a similar manner. A bi-metal coil spring may be wound around the piston.
摘要翻译： 一种磁性弹簧致动器，包括环，可移动地设置在所述环内部的活塞和非磁性保持筒。 环和活塞中的至少一个是磁性的。 由于由环和活塞中的至少一个引起的磁力，活塞最初位于相对于环的第一位置。 施加外力导致活塞相对于环移动到第二位置。 磁力产生使活塞相对于环返回到第一位置的返回力。 或者，活塞可以被固定，并且环可以适于相对于活塞以类似的方式移动。 双金属螺旋弹簧可以缠绕在活塞周围。
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