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1.发明授权公开(公告)号：US07420734B2
公开(公告)日：2008-09-02
申请号：US10526096
申请日：2003-08-26
IPC分类号： G02B5/18
CPC分类号： G02B6/124 , G02B5/1857 , G02B5/32 , G02B6/29325
摘要： Diffraction gratings are formed from grooves each having a reflective facet and a non-reflective facet. The net reflection of TE (Transverse Electric) and TM (Transverse Magnetic) polarizations from the grating structure is traded off against the polarization dependent reflection, by controlling the degree of metallization of the reflective facet and by ensuring that there is no metallization of non-reflective sidewalls. other diffraction gratings are manufactured from trenches etched perpendicular to a waveguide. The trenches are metallized and back-filled with a filling material having a refractive index matched to that of the waveguide. The gratings essentially have no non-reflecting sidewalls with insignificant polarization influence from side walls.
摘要翻译： 衍射光栅由各自具有反射小面和非反射小面的凹槽形成。 通过控制反射面的金属化程度，并通过确保不存在非金属化反射，通过光栅结构的TE（横向电）和TM（横向磁性）偏振的净反射抵消偏振相关反射， 反射侧壁。 其他衍射光栅由垂直于波导蚀刻的沟槽制造。 沟槽被金属化并用填充材料反向填充，该填充材料的折射率与波导的折射率相匹配。 光栅基本上不具有侧壁具有不显着偏振影响的非反射侧壁。
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2.发明授权Planar waveguide based grating device and spectrometer for species-specific wavelength detection 有权用于物种特异性波长检测的平面波导光栅装置和光谱仪公开(公告)号：US07324195B2
公开(公告)日：2008-01-29
申请号：US11031039
申请日：2005-01-10
CPC分类号： G01J3/2803 , B82Y10/00 , B82Y20/00 , G01J3/0259 , G01N21/05 , G01N21/31 , G01N21/6428 , G01N21/645 , G01N2021/0346 , G01N2021/058 , G01N2021/6482 , G01N2021/6484 , G02B6/12007
摘要： Planar waveguide based grating devices and spectrometers, for species-specific wavelength detection for example, are disclosed. A planar waveguide spectrometer apparatus may have a microfluidic channel or compartment microfabricated integrally with a planar waveguide or hybrid assembled with the planar waveguide and optically coupled thereto. The planar waveguide may also include a thin planar substrate which is made of a transparent waveguiding optical material and has a planar multilayer, one or more input waveguides, a waveguide-based spectrometer, and one or more output waveguides integrally formed thereon. An apparatus which incorporates a planar waveguide, a diffractive construct for diffracting light through the planar waveguide onto a curved image surface, and a plurality of output waveguides emanating from the curved image surface at locations selected to extract predetermined wavelengths or wavelength ranges, is also disclosed.
摘要翻译： 公开了用于物种特异性波长检测的基于平面波导的光栅装置和光谱仪。 平面波导光谱仪装置可以具有与平面波导或与平面波导组装的光学耦合的平面波导或混合物整体微加工的微流体通道或隔室。 平面波导还可以包括由透明波导光学材料制成并且具有平面多层，一个或多个输入波导，基于波导的光谱仪以及一体地形成在其上的一个或多个输出波导的薄平面基板。 还公开了一种装置，其包括平面波导，用于将光从平面波导衍射到弯曲图像表面上的衍射构造，以及从被选择提取预定波长或波长范围的位置处的弯曲图像表面发出的多个输出波导 。
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3.发明申请公开(公告)号：US20060119945A1
公开(公告)日：2006-06-08
申请号：US10526096
申请日：2003-08-26
IPC分类号： G02B5/18
CPC分类号： G02B6/124 , G02B5/1857 , G02B5/32 , G02B6/29325
摘要： Diffraction gratings are formed from grooves each having a reflective facet and a non-reflective facet. The net reflection of TE (Transverse Electric) and TM (Transverse Magnetic) polarizations from the grating structure is traded off against the polarization dependent reflection, by controlling the degree of metallization of the reflective facet and by ensuring that there is no metallization of non-reflective sidewalls. other diffraction gratings are manufactured from trenches etched perpendicular to a waveguide. The trenches are metallized and back-filled with a filling material having a refractive index matched to that of the waveguide. The gratings essentially have no non-reflecting sidewalls with insignificant polarization influence from side walls.
摘要翻译： 衍射光栅由各自具有反射小面和非反射小面的凹槽形成。 通过控制反射面的金属化程度，并通过确保不存在非金属化反射，通过光栅结构的TE（横向电）和TM（横向磁性）偏振的净反射抵消偏振相关反射， 反射侧壁。 其他衍射光栅由垂直于波导蚀刻的沟槽制造。 沟槽被金属化并用填充材料反向填充，该填充材料的折射率与波导的折射率相匹配。 光栅基本上不具有侧壁具有不显着偏振影响的非反射侧壁。
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4.发明申请Planar waveguide based grating device and spectrometer for species-specific wavelength detection 有权用于物种特异性波长检测的平面波导光栅装置和光谱仪公开(公告)号：US20050151966A1
公开(公告)日：2005-07-14
申请号：US11031039
申请日：2005-01-10
CPC分类号： G01J3/2803 , B82Y10/00 , B82Y20/00 , G01J3/0259 , G01N21/05 , G01N21/31 , G01N21/6428 , G01N21/645 , G01N2021/0346 , G01N2021/058 , G01N2021/6482 , G01N2021/6484 , G02B6/12007
摘要： Planar waveguide based grating devices and spectrometers, for species-specific wavelength detection for example, are disclosed. A planar waveguide spectrometer apparatus may have a microfluidic channel or compartment microfabricated integrally with a planar waveguide or hybrid assembled with the planar waveguide and optically coupled thereto. The planar waveguide may also include a thin planar substrate which is made of a transparent waveguiding optical material and has a planar multilayer, one or more input waveguides, a waveguide-based spectrometer, and one or more output waveguides integrally formed thereon. An apparatus which incorporates a planar waveguide, a diffractive construct for diffracting light through the planar waveguide onto a curved image surface, and a plurality of output waveguides emanating from the curved image surface at locations selected to extract predetermined wavelengths or wavelength ranges, is also disclosed.
摘要翻译： 公开了用于物种特异性波长检测的基于平面波导的光栅装置和光谱仪。 平面波导光谱仪装置可以具有与平面波导或与平面波导组装的光学耦合的平面波导或混合物整体微加工的微流体通道或隔室。 平面波导还可以包括由透明波导光学材料制成并且具有平面多层，一个或多个输入波导，基于波导的光谱仪以及一体地形成在其上的一个或多个输出波导的薄平面基板。 还公开了一种装置，其包括平面波导，用于将光从平面波导衍射到弯曲图像表面上的衍射构造，以及从被选择提取预定波长或波长范围的位置处的弯曲图像表面发出的多个输出波导 。
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公开(公告)号：US20130220032A1
公开(公告)日：2013-08-29
申请号：US13881673
申请日：2011-10-26
IPC分类号： G01L1/24
摘要： A sensing element for sensing a mechanical property of a sample defining a sample surface using a contact force exerted the sample surface. The sensing element includes: a deformable element defining a contact surface and a deformable section in register with the contact surface, the deformable section being deformable between an undeformed configuration and a deformed configuration; a deformation sensor operatively coupled to the deformable section for sensing and quantifying a deformation of the deformable section between the deformed and undeformed configurations, the deformation sensor being an optical deformation sensor; and a force sensor operatively coupled to the deformable element for sensing the contact force exerted on the contact surface.
摘要翻译： 感测元件，用于感测使用接触力施加样品表面的限定样品表面的样品的机械性能。 感测元件包括：可变形元件，其限定接触表面和与接触表面对准的可变形部分，可变形部分可在未变形构型和变形构型之间变形; 变形传感器，其可操作地耦合到所述变形部分，用于感测和量化所述变形部分在变形和未变形构型之间的变形，所述变形传感器是光学变形传感器; 以及力传感器，其可操作地联接到所述可变形元件，用于感测施加在所述接触表面上的接触力。
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公开(公告)号：US10564358B2
公开(公告)日：2020-02-18
申请号：US15992632
申请日：2018-05-30
摘要： Wavelength division multiplexing (WDM) has enabled telecommunication service providers to fully exploit the transmission capacity of optical fibers. State of the art systems in long-haul networks now have aggregated capacities of terabits per second. Moreover, by providing multiple independent multi-gigabit channels, WDM technologies offer service providers with a straight forward way to build networks and expand networks to support multiple clients with different requirements. In order to reduce costs, enhance network flexibility, reduce spares, and provide re-configurability many service providers have migrated away from fixed wavelength transmitters, receivers, and transceivers, to wavelength tunable transmitters, receivers, and transceivers as well as wavelength dependent add-drop multiplexer, space switches etc. However, to meet the competing demands for improved performance, increased integration, reduced footprint, reduced power consumption, increased flexibility, re-configurability, and lower cost it is desirable to exploit/adopt monolithic optical circuit technologies, hybrid optoelectronic integration, and microelectromechanical systems (MEMS).
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公开(公告)号：US20160265989A1
公开(公告)日：2016-09-15
申请号：US15163264
申请日：2016-05-24
IPC分类号： G01L1/24
CPC分类号： G01L1/242 , A61B34/30 , A61B34/76 , A61B2090/065 , G01B11/18 , G01D5/268 , G01D5/353 , G01L1/16 , G01L1/18 , G01L1/24 , G01L1/243 , G01M11/085
摘要： A sensing element for sensing a mechanical property of a sample defining a sample surface using a contact force exerted the sample surface. The sensing element includes: a deformable element defining a contact surface and a deformable section in register with the contact surface, the deformable section being deformable between an undeformed configuration and a deformed configuration; a deformation sensor operatively coupled to the deformable section for sensing and quantifying a deformation of the deformable section between the deformed and undeformed configurations, the deformation sensor being an optical deformation sensor; and a force sensor operatively coupled to the deformable element for sensing the contact force exerted on the contact surface.
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8.发明授权公开(公告)号：US08926906B2
公开(公告)日：2015-01-06
申请号：US13055364
申请日：2009-07-21
CPC分类号： G01N21/645 , G01N21/05 , G01N21/6428 , G01N2021/0325 , G01N2021/0346 , G01N2021/056 , G01N2021/6417 , G01N2021/6439 , G01N2021/6484 , G01N2201/062 , G01N2201/08 , Y10T29/494
摘要： The present application is directed to a technological platform with integrated microfluidic and optical modules for bio-detection. The platform enables in-situ detection by integrating fluidics with optical source and detection capabilities within a fabricated microchip. The platform is a polymer-based microfluidic chip having integrated excitation source and detection elements in a vicinity of a microfluidic reaction chamber configured to contain a micro-volume of a test sample. The principle of detection is based on an excitation source induced fluorescence of the test sample within the microfluidic reaction chamber.
摘要翻译： 本申请涉及具有用于生物检测的集成微流体和光学模块的技术平台。 该平台通过将流体学与光源和检测能力集成在制造的微芯片内，实现原位检测。 该平台是一种基于聚合物的微流体芯片，其具有在微流体反应室附近的集成的激发源和检测元件，该微流体反应室配置成容纳测试样品的微量体积。 检测原理是基于微流体反应室内测试样品的激发源诱导荧光。
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9.发明申请NANO-ENHANCED EVANESCENCE INTEGRATED TECHNIQUE (NEET) BASED MICROPHOTONIC DEVICE AND SAMPLE ANALYSIS SYSTEM 有权纳米增强型集成技术（NEET）基于微波器件和样品分析系统公开(公告)号：US20120269683A1
公开(公告)日：2012-10-25
申请号：US13395384
申请日：2010-09-16
CPC分类号： G02B6/1225 , B82Y20/00
摘要： A device, a method of fabricating the device and a sample analysis system that includes the device are provided. The device includes an optical waveguide having a plurality of nanofeatures integrated thereon to influence at least one of evanescence and coupling of an optical field of the optical waveguide. The sample analysis system includes a fluidic actuation system for introducing sample specimen fluid into a microfluidic channel of the device for evanescence based detection.
摘要翻译： 提供了一种器件，制造器件的方法和包括该器件的样品分析系统。 该器件包括其上集成有多个纳米尺度的光波导，以影响光波导的光场的消逝和耦合中的至少一个。 样品分析系统包括流体致动系统，用于将样品样品流体引入装置的微流体通道以进行基于消逝的检测。
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10.发明申请METHODS AND DEVICES FOR EARLY DETECTION OF CANCER CELLS AND TYPES THROUGH MICROMECHANICAL INTERACTIONS 审中-公开通过微生物相互作用早期检测癌细胞和类型的方法和装置公开(公告)号：US20120135891A1
公开(公告)日：2012-05-31
申请号：US13361328
申请日：2012-01-30
IPC分类号： G01N33/574 , C40B40/10 , C40B40/06 , C12Q1/68
CPC分类号： G01N33/5091 , G01N33/574
摘要： Methods and devices for detecting a cancer cell and cancer cell types in a sample of a subject are provided.
摘要翻译： 提供了用于检测受试者样品中的癌细胞和癌细胞类型的方法和装置。
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