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    PHARMACEUTICAL COMPOSITIONS COMPRISING MONOTERPENES
    2.
    发明申请
    PHARMACEUTICAL COMPOSITIONS COMPRISING MONOTERPENES 有权
    包含单体的药物组合物

    公开(公告)号：US20150368173A1

    公开(公告)日：2015-12-24

    申请号：US14817286

    申请日：2015-08-04

    Applicant: NEONC Technologies, Inc.

    Inventor： Thomas CHEN ,  DANIEL LEVIN ,  SATISH PUPPALI

    IPC: C07C29/88 ,  C07C201/12 ,  C07C67/14 ,  C07C201/16

    CPC classification number: C07C29/92 ,  A61K31/045 ,  A61K31/4188 ,  A61K45/06 ,  A61N5/10 ,  C07B2200/07 ,  C07C29/78 ,  C07C29/86 ,  C07C29/88 ,  C07C67/14 ,  C07C201/12 ,  C07C201/16 ,  C07C2601/16 ,  C07C33/14 ,  C07C205/57 ,  C07C69/76 ,  C07C69/92

    Abstract: The present invention provides a process for purifying a monoterpene or sesquiterpene having a purity greater than about 98.5% (w/w). The process comprises the steps of derivatizing the monoterpene (or sesquiterpene) to produce a monoterpene (or sesquiterpene) derivative, separating the monoterpene (or sesquiterpene) derivative, and releasing the monoterpene (or sesquiterpene) from the derivative. Also encompassed by the scope of the present invention is a pharmaceutical composition comprising a monoterpene (or sesquiterpene) having a purity greater than about 98.5% (w/w). The purified monoterpene can be used to treat a disease such as cancer. The present monoterpene (or sesquiterpene) may be administered alone, or may be co-administered with radiation or other therapeutic agents, such as chemotherapeutic agents.

    Abstract translation: 本发明提供纯化大于约98.5％（w / w）的单萜或倍半萜的方法。 该方法包括衍生单萜（或倍半萜烯）以产生单萜（或倍半萜烯）衍生物，分离单萜（或倍半萜烯）衍生物和从衍生物中释放单萜（或倍半萜烯）的步骤。 包括本发明范围的药物组合物是包含纯度大于约98.5％（w / w）的单萜（或倍半萜烯）的药物组合物。 纯化的单萜可用于治疗癌症等疾病。 本单萜（或倍半萜烯）可以单独施用，或者可以与辐射或其它治疗剂如化学治疗剂共同施用。

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