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公开(公告)号：US10308899B2
公开(公告)日：2019-06-04
申请号：US14786384
申请日：2014-04-23
Applicant: Novozymes A/S
Inventor： Hanne Philbert Nielsen , Lise Munch Mikkelsen , Martin Noerby , Juan Jiang
Abstract: The stabilization of subtilisins by peptide aldehydes, hydrosulfite adducts thereof or peptide methyl ketones, is particularly effective in liquid ADW detergents which contain a strong sequestering builder.
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公开(公告)号：US11312946B2
公开(公告)日：2022-04-26
申请号：US16423866
申请日：2019-05-28
Applicant: NOVOZYMES A/S
Inventor： Marco Malten , Kim Borch , Lise Munch Mikkelsen , Thomas Agersten Poulsen , Luise Erlandsen , Hanne Philbert Nielsen , Carsten Horslev Hansen , Allan Svendsen , Christian Lundager Gylstorff , Jesper Vind , Christian Jackel
Abstract: The present invention relates to detergent compositions comprising a variant of a parent lipase which variant has lipase activity, has at least 60% but less than 100% sequence identity with SEQ ID NO: 2, and comprises substitutions at positions corresponding to T231R+N233R and at least one or more (e.g., several) of D96E, D111A, D254S, G163K, P256T, G91T, and G38A of SEQ ID NO: 2. The present invention also relates to use of the compositions, methods of producing the compositions, and methods of cleaning.
The present invention furthermore relates to variants and polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides.-
公开(公告)号：US20190284541A1
公开(公告)日：2019-09-19
申请号：US16423866
申请日：2019-05-28
Applicant: NOVOZYMES A/S
Inventor： Marco Malten , Kim Borch , Lise Munch Mikkelsen , Thomas Agersten Poulsen , Luise Erlandsen , Hanne Philbert Nielsen , Carsten Horslev Hansen , Allan Svendsen , Christian Lundager Gylstorff , Jesper Vind , Christian Jackel
Abstract: The present invention relates to detergent compositions comprising a variant of a parent lipase which variant has lipase activity, has at least 60% but less than 100% sequence identity with SEQ ID NO: 2, and comprises substitutions at positions corresponding to T231R+N233R and at least one or more (e.g., several) of D96E, D111A, D254S, G163K, P256T, G91T, and G38A of SEQ ID NO: 2. The present invention also relates to use of the compositions, methods of producing the compositions, and methods of cleaning.The present invention furthermore relates to variants and polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides.
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公开(公告)号：US10351833B2
公开(公告)日：2019-07-16
申请号：US14785412
申请日：2014-05-13
Applicant: Novozymes A/S
Inventor： Marco Malten , Kim Borch , Lise Munch Mikkelsen , Thomas Agersten Poulsen , Luise Erlandsen , Hanne Philbert Nielsen , Carsten Horslev Hansen , Allan Svendsen , Christian Lundager Gylstorff , Jesper Vind , Christian Jackel
Abstract: The present invention relates to detergent compositions comprising a variant of a parent lipase which variant has lipase activity, has at least 60% but less than 100% sequence identity with SEQ ID NO: 2, and comprises substitutions at positions corresponding to T231R+N233R and at least one or more (e.g., several) of D96E, D111A, D254S, G163K, P256T, G91T, and G38A of SEQ ID NO: 2. The present invention also relates to use of the compositions, methods of producing the compositions, and methods of cleaning. The present invention furthermore relates to variants and polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides.
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Patent Agency Ranking
公开(公告)号：US20160076012A1
公开(公告)日：2016-03-17
申请号：US14785412
申请日：2014-05-13
Applicant: Novozymes A/S
Inventor： Marco Malten , Kim Borch , Lise Munch Mikkelsen , Thomas Agersten Poulsen , Luise Erlandsen , Hanne Philbert Nielsen , Carsten Horslev Hansen , Allan Svendsen , Christian Lundager Glystorff , Jesper Vind , Christian Jackel
CPC classification number: C12N9/18 , A61K8/66 , B65D65/46 , C11D3/38627 , C11D17/042 , C11D17/043 , C12N9/20 , C12Y301/01 , C12Y301/01003
Abstract: The present invention relates to detergent compositions comprising a variant of a parent lipase which variant has lipase activity, has at least 60% but less than 100% sequence identity with SEQ ID NO: 2, and comprises substitutions at positions corresponding to T231R+N233R and at least one or more (e.g., several) of D96E, D111A, D254S, G163K, P256T, G91T, and G38A of SEQ ID NO: 2. The present invention also relates to use of the compositions, methods of producing the compositions, and methods of cleaning. The present invention furthermore relates to variants and polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides.
Abstract translation: 本发明涉及包含变体具有脂肪酶活性的母体脂肪酶的变体的洗涤剂组合物与SEQ ID NO：2具有至少60％但小于100％的序列同一性，并且包括在对应于T231R + N233R的位置和 SEQ ID NO：2的D96E，D111A，D254S，G163K，P256T，G91T和G38A的至少一个或多个（例如数个）。本发明还涉及组合物的用途， 清洁方法 本发明还涉及编码变体的变体和多核苷酸; 核酸构建体，载体和包含多核苷酸的宿主细胞。
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公开(公告)号：US20250002880A1
公开(公告)日：2025-01-02
申请号：US18826915
申请日：2024-09-06
Applicant: Novozymes A/S
Inventor： Marco Malten , Kim Borch , Lise Munch Mikkelsen , Thomas Agersten Poulsen , Luise Erlandsen , Hanne Philbert Nielsen , Carsten Horslev Hansen , Allan Svendsen , Christian Lundager Gylstorff , Jesper Vind , Christian Jackel
Abstract: The present invention relates to detergent compositions comprising a variant of a parent lipase which variant has lipase activity, has at least 60% but less than 100% sequence identity with SEQ ID NO: 2, and comprises substitutions at positions corresponding to T231R+N233R and at least one or more (e.g., several) of D96E, D111A, D254S, G163K, P256T, G91T, and G38A of SEQ ID NO: 2. The present invention also relates to use of the compositions, methods of producing the compositions, and methods of cleaning.
The present invention furthermore relates to variants and polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides.-
公开(公告)号：US12116601B2
公开(公告)日：2024-10-15
申请号：US17700598
申请日：2022-03-22
Applicant: Novozymes A/S
Inventor： Marco Malten , Kim Borch , Lise Munch Mikkelsen , Thomas Agersten Poulsen , Luise Erlandsen , Hanne Philbert Nielsen , Carsten Horslev Hansen , Allan Svendsen , Christian Lundager Gylstorff , Jesper Vind , Christian Jackel
CPC classification number: C12N9/18 , A61K8/66 , B65D65/46 , C11D3/38627 , C11D17/042 , C11D17/043 , C12N9/20 , C12Y301/01003 , C12Y301/01
Abstract: The present invention relates to detergent compositions comprising a variant of a parent lipase which variant has lipase activity, has at least 60% but less than 100% sequence identity with SEQ ID NO: 2, and comprises substitutions at positions corresponding to T231R+N233R and at least one or more (e.g., several) of D96E, D111A, D254S, G163K, P256T, G91T, and G38A of SEQ ID NO: 2. The present invention also relates to use of the compositions, methods of producing the compositions, and methods of cleaning. The present invention furthermore relates to variants and polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides.
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公开(公告)号：US20220213453A1
公开(公告)日：2022-07-07
申请号：US17700598
申请日：2022-03-22
Applicant: Novozymes A/S
Inventor： Marco Malten , Kim Borch , Lise Munch Mikkelsen , Thomas Agersten Poulsen , Luise Erlandsen , Hanne Philbert Nielsen , Carsten Horslev Hansen , Allan Svendsen , Christian Lundager Gylstorff , Jesper Vind , Christian Jackel
Abstract: The present invention relates to detergent compositions comprising a variant of a parent lipase which variant has lipase activity, has at least 60% but less than 100% sequence identity with SEQ ID NO: 2, and comprises substitutions at positions corresponding to T231R+N233R and at least one or more (e.g., several) of D96E, D111A, D254S, G163K, P256T, G91T, and G38A of SEQ ID NO: 2. The present invention also relates to use of the compositions, methods of producing the compositions, and methods of cleaning.
The present invention furthermore relates to variants and polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides.-
公开(公告)号：US20160068788A1
公开(公告)日：2016-03-10
申请号：US14786384
申请日：2014-04-23
Applicant: NOVOZYMES A/S
Inventor： Hanne Philbert Nielsen , Lise Munch Mikkelsen , Martin Noerby , Juan Jiang
IPC: C11D3/386
CPC classification number: C11D3/38663 , C07K5/06026 , C07K5/06043 , C07K5/06052 , C07K5/06095 , C07K5/0806 , C07K5/0808 , C07K5/0812 , C07K5/0817 , C11D3/38618
Abstract: The stabilization of subtilisins by peptide aldehydes, hydrosulfite adducts thereof or peptide methyl ketones, is particularly effective in liquid ADW detergents which contain a strong sequestering builder.
Abstract translation: 通过肽醛，其连二亚硫酸酯加合物或肽甲基酮稳定枯草杆菌蛋白酶在含有强螯合助洗剂的液体ADW洗涤剂中特别有效。
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