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    Affinity-based detection of biological targets
    1.
    发明授权
    Affinity-based detection of biological targets 有权
    基于亲和力的生物靶标检测

    公开(公告)号：US08945856B2

    公开(公告)日：2015-02-03

    申请号：US14188784

    申请日：2014-02-25

    申请人： Nadezhda V. Kulagina ,  Chris Rowe Taitt ,  George P. Anderson ,  Frances S. Ligler

    发明人： Nadezhda V. Kulagina ,  Chris Rowe Taitt ,  George P. Anderson ,  Frances S. Ligler

    IPC分类号： G01N33/53 ,  G01N33/569 ,  G01N33/554 ,  G01N33/543

    CPC分类号： G01N33/56916 ,  G01N33/5308 ,  G01N33/54366 ,  G01N33/554 ,  G01N33/56911 ,  G01N33/56983

    摘要： A method of biochemical identification by: providing a plurality of capture species bound to one or more substrates and suspected of having one or more biological targets affinity bound to at least one capture species; detecting which capture species contain bound biological targets to generate a binding pattern; and identifying the biological target based on the binding pattern. The capture species are independently selected from the group consisting of antimicrobial peptides, cytotoxic peptides, antibiotics, and combinations thereof. A device having the capture species bound to the substrates. At least two of the capture species are capable of multi-specific binding to one or more biological targets and may have overlapping but not identical affinity properties.

    摘要翻译： 生物化学鉴定的方法是：提供与一种或多种底物结合的多种捕获物质，并怀疑具有与至少一种捕获物质结合的一种或多种生物靶标; 检测哪些捕获物种含有结合的生物靶标以产生结合模式; 以及基于所述结合模式识别所述生物学目标。 捕获物种独立地选自抗微生物肽，细胞毒性肽，抗生素及其组合。 具有捕获物质与基底结合的装置。 至少两种捕获物质能够与一种或多种生物靶标进行多特异性结合，并且可以具有重叠但不相同的亲和性质。

    Affinity-based detection of biological targets
    2.
    发明授权
    Affinity-based detection of biological targets 有权
    基于亲和力的生物靶标检测

    公开(公告)号：US08658372B2

    公开(公告)日：2014-02-25

    申请号：US11307399

    申请日：2006-02-06

    申请人： Nadezhda V Kulagina ,  Chris Rowe Taitt ,  George P Anderson ,  Frances S Ligler

    发明人： Nadezhda V Kulagina ,  Chris Rowe Taitt ,  George P Anderson ,  Frances S Ligler

    IPC分类号： G01N33/53

    CPC分类号： G01N33/56916 ,  G01N33/5308 ,  G01N33/54366 ,  G01N33/554 ,  G01N33/56911 ,  G01N33/56983

    摘要： A method of biochemical identification by: providing a plurality of capture species bound to one or more substrates and suspected of having one or more biological targets affinity bound to at least one capture species; detecting which capture species contain bound biological targets to generate a binding pattern; and identifying the biological target based on the binding pattern. The capture species are independently selected from the group consisting of antimicrobial peptides, cytotoxic peptides, antibiotics, and combinations thereof. A device having the capture species bound to the substrates. At least two of the capture species are capable of multi-specific binding to one or more biological targets and may have overlapping but not identical affinity properties.

    摘要翻译： 生物化学鉴定的方法是：提供与一种或多种底物结合的多种捕获物质，并怀疑具有与至少一种捕获物质结合的一种或多种生物靶标; 检测哪些捕获物种含有结合的生物靶标以产生结合模式; 以及基于所述结合模式识别所述生物学目标。 捕获物种独立地选自抗微生物肽，细胞毒性肽，抗生素及其组合。 具有捕获物质与基底结合的装置。 至少两种捕获物质能够与一种或多种生物靶标进行多特异性结合，并且可以具有重叠但不相同的亲和性质。

    AFFINITY-BASED DETECTION OF BIOLOGICAL TARGETS
    3.
    发明申请
    AFFINITY-BASED DETECTION OF BIOLOGICAL TARGETS 有权
    基于生物目标的基于亲属的检测

    公开(公告)号：US20140187446A1

    公开(公告)日：2014-07-03

    申请号：US14188784

    申请日：2014-02-25

    申请人： Nadezhda V. Kulagina ,  Chris Rowe Taitt ,  George P. Anderson ,  Frances S. Ligler

    发明人： Nadezhda V. Kulagina ,  Chris Rowe Taitt ,  George P. Anderson ,  Frances S. Ligler

    IPC分类号： G01N33/569 ,  G01N33/543

    CPC分类号： G01N33/56916 ,  G01N33/5308 ,  G01N33/54366 ,  G01N33/554 ,  G01N33/56911 ,  G01N33/56983

    摘要： A method of biochemical identification by: providing a plurality of capture species bound to one or more substrates and suspected of having one or more biological targets affinity bound to at least one capture species; detecting which capture species contain bound biological targets to generate a binding pattern; and identifying the biological target based on the binding pattern. The capture species are independently selected from the group consisting of antimicrobial peptides, cytotoxic peptides, antibiotics, and combinations thereof. A device having the capture species bound to the substrates. At least two of the capture species are capable of multi-specific binding to one or more biological targets and may have overlapping but not identical affinity properties.

    摘要翻译： 生物化学鉴定的方法是：提供与一种或多种底物结合的多种捕获物质，并怀疑具有与至少一种捕获物质结合的一种或多种生物靶标; 检测哪些捕获物种含有结合的生物靶标以产生结合模式; 以及基于所述结合模式识别所述生物学目标。 捕获物种独立地选自抗微生物肽，细胞毒性肽，抗生素及其组合。 具有捕获物质与基底结合的装置。 至少两种捕获物质能够与一种或多种生物靶标进行多特异性结合，并且可以具有重叠但不相同的亲和性质。