公开(公告)号：US09529184B2

公开(公告)日：2016-12-27

申请号：US13363061

申请日：2012-01-31

申请人： Naoki Fukutake ,  Shinichi Nakajima

发明人： Naoki Fukutake ,  Shinichi Nakajima

IPC分类号： G06K9/46 ,  G02B21/14 ,  G02B21/36

CPC分类号： G02B21/14 ,  G02B21/367

摘要： An imaging apparatus includes an imaging unit that images a test object, an analysis unit that outputs a feature amount of an image which is captured by the imaging unit, a storage unit that stores an evaluation function which has the image feature amount as a variable, for evaluation of the image, a selection unit that selects one image from two or more images including an image specified based on a value of the evaluation function, and a changing unit that changes the evaluation function based on the one image in a case where the one image selected by the selection unit is different from the specified image.

摘要翻译： 一种成像装置，包括对被检体进行成像的成像单元，输出由摄像单元拍摄的图像的特征量的分析单元，存储具有图像特征量的评价函数作为变量的存储单元， 用于评估图像的选择单元，从包括基于评估函数的值指定的图像的两个或多个图像中选择一个图像的选择单元，以及在所述图像的情况下基于所述一个图像改变评估函数的改变单元 由选择单元选择的一个图像与指定的图像不同。

公开(公告)号：US09563048B2

公开(公告)日：2017-02-07

申请号：US13362642

申请日：2012-01-31

申请人： Naoki Fukutake ,  Shinichi Nakajima ,  Hirohisa Taira

发明人： Naoki Fukutake ,  Shinichi Nakajima ,  Hirohisa Taira

IPC分类号： H04N7/18 ,  G02B21/14 ,  G02B21/12 ,  G02B21/36 ,  G06K9/20

CPC分类号： G02B21/14 ,  G02B21/12 ,  G02B21/365 ,  G06K9/2027

摘要： A microscope includes an illuminating optical system that illuminates the test object under predetermined illumination conditions, an imaging optical system that forms an image of the test object, and an image sensor that outputs an image signal. A computer includes an image analyzing unit that acquires an image feature amount of the test object on the basis of the image signal detected by the image sensor, a comparison unit that compares the image feature amount of the test object with image feature amounts of a plurality of sample test objects and specifies an image feature amount of a sample test object closest to the image feature amount of the test object, and a setting unit that sets illumination conditions of the illuminating optical system on the basis of an illumination state suitable for observation of a sample test object having the image feature amount specified by the comparison unit.

摘要翻译： 显微镜包括：照明光学系统，其在预定照明条件下照射被检查物体;成像光学系统，其形成测试对象的图像;以及图像传感器，其输出图像信号。 计算机包括：图像分析单元，其基于由图像传感器检测到的图像信号获取测试对象的图像特征量;比较单元，其将测试对象的图像特征量与多个图像特征量进行比较; 并且指定最接近测试对象的图像特征量的样本测试对象的图像特征量;以及设置单元，其基于适合于观察对象的照明状态来设置照明光学系统的照明条件 具有由比较单元指定的图像特征量的样本测试对象。

公开(公告)号：US09261690B2

公开(公告)日：2016-02-16

申请号：US13359164

申请日：2012-01-26

申请人： Naoki Fukutake ,  Hiroki Yazawa ,  Shigeru Nakayama ,  Shinichi Nakajima

发明人： Naoki Fukutake ,  Hiroki Yazawa ,  Shigeru Nakayama ,  Shinichi Nakajima

IPC分类号： H04N7/18 ,  H04N9/47 ,  G02B21/14 ,  G02B21/36

CPC分类号： G02B21/14 ,  G02B21/365 ,  G02B21/367

摘要： A phase-contrast microscope system includes: an illumination optical system that illuminates a specimen with an illumination light from a light source; an imaging optical system that forms an image of the specimen from a light from the specimen; a first spatial modulation element that is disposed in a position of a pupil of the imaging optical system and changes an amplitude transmittance distribution of the light from the specimen; an image sensor that detects the image of the specimen by the imaging optical system and outputs a picture signal; a calculation section that calculates the amplitude transmittance distribution of the light from the specimen appropriate for observing the specimen on the basis of the output data detected by the image sensor and the amplitude transmittance distribution of the light from the specimen formed by the first spatial modulation element.

摘要翻译： 相差显微镜系统包括：照明光学系统，其利用来自光源的照明光照射样本; 成像光学系统，其从来自所述样本的光形成所述样本的图像; 第一空间调制元件，其设置在所述摄像光学系统的光瞳的位置，并且改变来自所述检体的光的透射率分布; 图像传感器，其通过所述成像光学系统检测所述检体的图像，并输出图像信号; 计算部，其根据由图像传感器检测的输出数据和来自第一空间调制元件形成的试样的光的振幅透射率分布，计算适合于观察样本的样本的光的透射率分布 。

公开(公告)号：US20080259345A1

公开(公告)日：2008-10-23

申请号：US12050645

申请日：2008-03-18

申请人： Naoki Fukutake

发明人： Naoki Fukutake

IPC分类号： G01B9/02

CPC分类号： G02B21/18 ,  A61B90/20 ,  G02B21/367 ,  G03H1/0005 ,  G03H1/0443 ,  G03H1/0866 ,  G03H2001/005 ,  G03H2001/0445 ,  G03H2001/0469 ,  G03H2001/0471 ,  G03H2001/0473 ,  G03H2222/16 ,  G03H2222/36

摘要： A microscope which has a high three-dimensional resolution, does not require specimens to be stained and is easy to operate, is presented. The three-dimensional microscope includes a first optical system for illuminating an object with lights in a plurality of illuminating directions, one direction after another; an imaging section; a second optical system for guiding diffracted lights generated by the object and reference lights to the imaging section that obtains interference images of the diffracted lights and the reference lights; and a processor for generating a three-dimensional image using the interference images for respective illuminating directions, obtained by the imaging section. The processor obtains complex amplitudes of the diffracted lights from the interference images for respective illuminating directions and generates the three-dimensional image of the object from the complex amplitudes.

摘要翻译： 具有高三维分辨率的显微镜不需要标本染色并易于操作。 三维显微镜包括：第一光学系统，用于沿着多个照明方向用一个方向照亮物体; 成像部分; 用于将由物体产生的衍射光和参考光引导到获得衍射光和参考光的干涉图像的成像部分的第二光学系统; 以及处理器，用于使用由成像部获得的各个照明方向的干涉图像来生成三维图像。 处理器从相应的照明方向的干涉图像中获得衍射光的复振幅，并从复振幅产生物体的三维图像。

公开(公告)号：US5889618A

公开(公告)日：1999-03-30

申请号：US961569

申请日：1997-10-30

申请人： Naoki Fukutake

发明人： Naoki Fukutake

IPC分类号： G02B21/02

CPC分类号： G02B21/02

摘要： An inexpensive achromatic object lens for a microscope has a magnification of about 20 and a relatively long working distance. Aberrations are satisfactorily corrected even at the periphery of the image. The object lens includes a first lens group having a positive refractive power, a second lens group having a positive refractive power, and a third lens group having a negative refractive power in this order from the object side. The first lens group consists of a positive lens and a cemented lens which is composed of a negative lens and a positive lens. The second lens group consists of a positive lens for converting the divergent light flux that has exited the first lens group into convergent light flux. The third lens group consists of a negative meniscus lens with its concave surface facing the image side. The object lens satisfies the conditions 4.0.ltoreq.f1/d0.ltoreq.15.0, 55.ltoreq.v2p, and 35.ltoreq.v1p-v1n.

摘要翻译： 用于显微镜的便宜的消色差物镜具有约20的放大率和相对较长的工作距离。 即使在图像的周围也能令人满意地校正像差。 该物镜包括具有正折光力的第一透镜组，具有正折射光焦度的第二透镜组和从物体侧起依次具有负折光力的第三透镜组。 第一透镜组由正透镜和由透镜和正透镜组成的胶合透镜组成。 第二透镜组包括用于将已经退出第一透镜组的发散光束转换成会聚光束的正透镜。 第三透镜组由凹面朝向像侧的负凹凸透镜组成。 物镜满足条件4.0

公开(公告)号：US6128139A

公开(公告)日：2000-10-03

申请号：US961054

申请日：1997-10-30

申请人： Naoki Fukutake

发明人： Naoki Fukutake

IPC分类号： G02B9/12 ,  G02B21/02

CPC分类号： G02B9/12 ,  G02B21/02

摘要： An achromat-class microscope objective lens, which has a magnification of about 10 times and in which various types of aberration are corrected in peripheral portions of an image, includes a first lens group having a cemented lens composed of a double-concave lens and a double-convex lens, a second lens group having a positive lens, and a third lens group having a cemented lens composed of a double-concave lens and a double-convex lens. The first, second and third lens groups are arranged in that order from an object. The microscope objective lens satisfies certain predetermined expressions.

摘要翻译： 具有大约10倍的放大倍率并且在图像的周边部分校正各种像差的消色差级显微镜物镜包括具有由双凹透镜构成的胶合透镜的第一透镜组和 双凸透镜，具有正透镜的第二透镜组和具有由双凹透镜和双凸透镜构成的胶合透镜的第三透镜组。 第一，第二和第三透镜组按照从物体的顺序排列。 显微镜物镜满足某些预定表达。

公开(公告)号：US07633631B2

公开(公告)日：2009-12-15

申请号：US12050645

申请日：2008-03-18

申请人： Naoki Fukutake

发明人： Naoki Fukutake

IPC分类号： G01B9/02 ,  G01B11/02 ,  G01D5/36

CPC分类号： G02B21/18 ,  A61B90/20 ,  G02B21/367 ,  G03H1/0005 ,  G03H1/0443 ,  G03H1/0866 ,  G03H2001/005 ,  G03H2001/0445 ,  G03H2001/0469 ,  G03H2001/0471 ,  G03H2001/0473 ,  G03H2222/16 ,  G03H2222/36

摘要： A microscope which has a high three-dimensional resolution, does not require specimens to be stained and is easy to operate, is presented. The three-dimensional microscope includes a first optical system for illuminating an object with lights in a plurality of illuminating directions, one direction after another; an imaging section; a second optical system for guiding diffracted lights generated by the object and reference lights to the imaging section that obtains interference images of the diffracted lights and the reference lights; and a processor for generating a three-dimensional image using the interference images for respective illuminating directions, obtained by the imaging section. The processor obtains complex amplitudes of the diffracted lights from the interference images for respective illuminating directions and generates the three-dimensional image of the object from the complex amplitudes.

摘要翻译： 具有高三维分辨率的显微镜不需要标本染色并易于操作。 三维显微镜包括：第一光学系统，用于沿着多个照明方向用一个方向照亮物体; 成像部分; 用于将由物体产生的衍射光和参考光引导到获得衍射光和参考光的干涉图像的成像部分的第二光学系统; 以及处理器，用于使用由成像部获得的各个照明方向的干涉图像来生成三维图像。 处理器从相应的照明方向的干涉图像中获得衍射光的复振幅，并从复振幅产生物体的三维图像。