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公开(公告)号:US08550497B2
公开(公告)日:2013-10-08
申请号:US13009543
申请日:2011-01-19
申请人: Naoyuki Takezawa , Yoshiyuki Sato , Toru Ito
发明人: Naoyuki Takezawa , Yoshiyuki Sato , Toru Ito
IPC分类号: B62D1/18
摘要: Provided is a steering device in which play of a bolt shaft and the like during telescopic adjustment can be prevented using a telescopic adjustment function enabling a driver to adjust a position of a steering wheel in a front-rear direction. The steering device includes a column pipe, an outer housing, a fixed bracket, a stopper bracket, a tightening member having a bolt shaft, a slide guide, an elastic stopper rubber material mounted on the slide guide, and an elastic pushing member in which torsional coil spring portions are formed at both axial ends of a pushing shaft portion. The bolt shaft is passed through a tightening hole of the outer housing and a support hole of the fixed bracket along shaft support portions of the slide guide, and the elastic pushing member is locked and fixed to the fixed bracket.
摘要翻译: 提供了一种转向装置,其中可以使用伸缩调节功能来防止伸缩调节期间的螺栓轴等的游隙,从而能够使驾驶员在前后方向上调整方向盘的位置。 转向装置包括柱管,外壳,固定支架,止动支架,具有螺栓轴的紧固构件,滑动导轨,安装在滑动导轨上的弹性止动橡胶材料以及弹性推动构件, 扭转螺旋弹簧部分形成在推动轴部分的两个轴向端部处。 螺栓轴穿过外壳的紧固孔和固定支架的支撑孔沿着滑动引导件的轴支撑部分,并且弹性推动构件被锁定并固定到固定支架。
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公开(公告)号:US20110175335A1
公开(公告)日:2011-07-21
申请号:US13009543
申请日:2011-01-19
申请人: Naoyuki Takezawa , Yoshiyuki Sato , Toru Ito
发明人: Naoyuki Takezawa , Yoshiyuki Sato , Toru Ito
IPC分类号: B62D1/185
摘要: Provided is a steering device in which play of a bolt shaft and the like during telescopic adjustment can be prevented using a telescopic adjustment function enabling a driver to adjust a position of a steering wheel in a front-rear direction. The steering device includes a column pipe, an outer housing, a fixed bracket, a stopper bracket, a tightening member having a bolt shaft, a slide guide, an elastic stopper rubber material mounted on the slide guide, and an elastic pushing member in which torsional coil spring portions are formed at both axial ends of a pushing shaft portion. The bolt shaft is passed through a tightening hole of the outer housing and a support hole of the fixed bracket along shaft support portions of the slide guide, and the elastic pushing member is locked and fixed to the fixed bracket.
摘要翻译: 提供了一种转向装置,其中可以使用伸缩调节功能来防止伸缩调节期间的螺栓轴等的游隙,从而能够使驾驶员在前后方向上调整方向盘的位置。 转向装置包括柱管,外壳,固定支架,止动支架,具有螺栓轴的紧固构件,滑动导轨,安装在滑动导轨上的弹性止动橡胶材料以及弹性推动构件, 扭转螺旋弹簧部分形成在推动轴部分的两个轴向端部处。 螺栓轴穿过外壳的紧固孔和固定支架的支撑孔沿着滑动引导件的轴支撑部分,并且弹性推动构件被锁定并固定到固定支架。
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公开(公告)号:US20120198956A1
公开(公告)日:2012-08-09
申请号:US13363299
申请日:2012-01-31
申请人: Naoyuki TAKEZAWA , Yoshiyuki Sato
发明人: Naoyuki TAKEZAWA , Yoshiyuki Sato
IPC分类号: B62D1/187
摘要: A steering device includes an outer column including fastening pieces formed to face each other at both sides, in the width direction, of a slot portion formed at either of a lower side or an upper side of an embracing body portion along an axial direction thereof, a fixed bracket clamping the outer column, a fastener that fastens the outer column and the fixed bracket, an inner column, and a pushing member having an expanding shaft portion. The two fastening pieces of the embracing body portion are connected by the fastener so that the two fastening pieces can be expanded and contracted, and the expanding shaft portion is elastically biased in an axial center direction of the outer column so as to abut on end zones of the slot portion and expand the two fastening pieces.
摘要翻译: 转向装置包括外柱,该外柱包括形成为沿宽度方向彼此面对的紧固件,所述紧固件形成在沿其轴向方向的包围主体部分的下侧或上侧的槽部中, 夹紧外柱的固定支架,紧固外柱和固定支架的紧固件,内柱和具有扩张轴部分的推动构件。 包围主体部分的两个紧固件通过紧固件连接,使得两个紧固件可以膨胀和收缩,并且扩展轴部分沿外柱的轴向中心方向弹性偏置,以便抵靠端部区域 并扩大两个紧固件。
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公开(公告)号:US08826769B2
公开(公告)日:2014-09-09
申请号:US13363299
申请日:2012-01-31
申请人: Naoyuki Takezawa , Yoshiyuki Sato
发明人: Naoyuki Takezawa , Yoshiyuki Sato
摘要: A steering device includes an outer column including fastening pieces formed to face each other at both sides, in the width direction, of a slot portion formed at either of a lower side or an upper side of an embracing body portion along an axial direction thereof, a fixed bracket clamping the outer column, a fastener that fastens the outer column and the fixed bracket, an inner column, and a pushing member having an expanding shaft portion. The two fastening pieces of the embracing body portion are connected by the fastener so that the two fastening pieces can be expanded and contracted, and the expanding shaft portion is elastically biased in an axial center direction of the outer column so as to abut on end zones of the slot portion and expand the two fastening pieces.
摘要翻译: 转向装置包括外柱,该外柱包括形成为沿宽度方向彼此面对的紧固件,所述紧固件形成在沿其轴向方向的包围主体部分的下侧或上侧的槽部中, 夹紧外柱的固定支架,紧固外柱和固定支架的紧固件,内柱和具有扩张轴部分的推动构件。 包围主体部分的两个紧固件通过紧固件连接,使得两个紧固件可以膨胀和收缩,并且扩展轴部分沿外柱的轴向中心方向弹性偏置,以便抵靠端部区域 并扩大两个紧固件。
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公开(公告)号:US20080305081A1
公开(公告)日:2008-12-11
申请号:US12002546
申请日:2007-12-18
IPC分类号: A61K38/21 , C07D471/04 , A61K39/395 , A61K33/24 , A61K38/50 , A61P35/00 , A61K31/506
CPC分类号: C07D471/04
摘要: The present invention relates to a compound represented by Formula [I]: or a pharmaceutically acceptable salt or ester thereof, wherein R1 and R2, which may be the same or different, are each a hydrogen atom, a lower alkyl group, a cycloalkyl group, or the like; R3 and R4, which may be the same or different, are each a hydrogen atom, a lower alkyl group, NRaRb, a phenyl group, a lower alkyl group substituted with a phenyl group, a 4- to 7-membered aliphatic heterocyclic group, a lower alkyl group substituted with a 4- to 7-membered aliphatic heterocyclic group, a 5- or 6-membered aromatic heterocyclic group, a lower alkyl group substituted with a 5- or 6-membered aromatic heterocyclic group, or the like; and R5 is a hydrogen atom, a cyano group, a halogen atom, or a lower alkyl group.
摘要翻译: 本发明涉及由式[I]表示的化合物或其药学上可接受的盐或酯,其中R 1和R 2可以相同或不同,分别为氢原子,低级烷基,环烷基 ,等等; R 3和R 4可以相同或不同,分别为氢原子,低级烷基,NR a R b,苯基,被苯基取代的低级烷基,4-至7-元脂族杂环基, 被4-至7-元脂族杂环基取代的低级烷基,5或6元芳族杂环基,被5或6元芳族杂环基取代的低级烷基等; R5为氢原子,氰基,卤素原子或低级烷基。
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公开(公告)号:US20080070894A1
公开(公告)日:2008-03-20
申请号:US11661486
申请日:2005-08-30
申请人: Mikako Kawamura , Takashi Hashihayata , Satoshi Sunami , Tetsuya Sugimoto , Fuyuki Yamamoto , Yoshiyuki Sato , Kaori Kamijo , Morihiro Mitsuya , Yoshikazu Iwasawa , Hideya Komatani
发明人: Mikako Kawamura , Takashi Hashihayata , Satoshi Sunami , Tetsuya Sugimoto , Fuyuki Yamamoto , Yoshiyuki Sato , Kaori Kamijo , Morihiro Mitsuya , Yoshikazu Iwasawa , Hideya Komatani
IPC分类号: A61K31/397 , A61K31/496 , A61K31/497 , A61K31/501 , A61K31/506 , A61K31/52 , A61K31/5377 , A61K31/5513 , A61P35/00 , C07D237/06 , C07D239/24 , C07D243/14 , C07D295/00 , C07D473/00
CPC分类号: C07D471/04 , C07D487/04
摘要: The present invention relates to a compound represented by Formula [I] or a pharmaceutically acceptable salt or ester thereof: wherein: X1, X2, X3, and X4, which may be identical or different, are each C or N, provided that none to two of X1, X2, X3, and X4 is/are N; Y is CH or N; R1, R1′, R2, R2′, R3, R3′, R4, and R4′, which may be identical or different, are each a hydrogen atom, a lower alkyl group, or the like; R5 is a hydrogen atom or a methyl group; R6 and R7, which may be identical or different, are each a hydrogen atom, a lower alkyl group, or the like; R8 and R8′, which may be identical or different, are each a hydrogen atom, a lower alkyl group, or the like; R9 is an aryl group or a heteroaryl group which may be substituted; and n is an integer from 1 to 3, and a PLK1 inhibitor or an anticancer agent containing the same.
摘要翻译: 本发明涉及由式[I]表示的化合物或其药学上可接受的盐或酯:其中:X 1,X 2,X 3, / SUB>和X 4可以相同或不同,各自为C或N,条件是X 1,X 2, / SUB>,X 3和X 4是N; Y是CH或N; R 1,R 1,R 2,R 2,R 3,N 3, R 3,R 4,R 4,R 4和R 4可以相同或不同,分别为氢原子,低级 烷基等; R 5是氢原子或甲基; R 6和R 7可以相同或不同,分别为氢原子,低级烷基等; R 8和R 8可以相同或不同,分别为氢原子,低级烷基等; R 9是可以被取代的芳基或杂芳基; n为1〜3的整数,PLK1抑制剂或含有该PLK1抑制剂的抗癌剂。
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公开(公告)号:USD563213S1
公开(公告)日:2008-03-04
申请号:US29262524
申请日:2006-07-05
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公开(公告)号:US06777410B2
公开(公告)日:2004-08-17
申请号:US10408220
申请日:2003-04-08
IPC分类号: A61K31423
CPC分类号: C07D498/04
摘要: This invention relates to compounds represented by the general formula [I] wherein, R represents an azido group, etc., R1 and R2 are the same or different and represent hydrogen atoms, etc., R3 and R4 are the same or different and represent hydrogen atoms, etc., X1 represents an oxygen atom, etc., X2 represents an oxygen atom, etc., Y represents an oxygen atom, etc., and Z represents a condensed aryl group, etc., or a pharmaceutically acceptable salt thereof, preparation processes thereof, and an agent for treating diabetes, a prophylactic agent for chronic complications of diabetes or a drug against obesity, containing, as an effective ingredient, the compound or the pharmaceutically acceptable salt thereof.
摘要翻译: 本发明涉及由通式[I]表示的化合物,其中R表示叠氮基等,R 1和R 2相同或不同,表示氢原子等,R 3, 和R 4相同或不同,表示氢原子等,X 1表示氧原子等,X 2表示氧原子等,Y表示氧原子等,Z表示缩合 芳基等,或其药学上可接受的盐,其制备方法和用于治疗糖尿病的药物,用于糖尿病慢性并发症的预防剂或抗肥胖药物,其含有作为有效成分的化合物或药学上可接受的盐 其可接受的盐。
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公开(公告)号:US06468460B2
公开(公告)日:2002-10-22
申请号:US09330919
申请日:1999-06-11
申请人: Shigeru Kinpara , Yoshiyuki Sato , Hisayoshi Osumi , Senji Suzuki
发明人: Shigeru Kinpara , Yoshiyuki Sato , Hisayoshi Osumi , Senji Suzuki
IPC分类号: B29C4514
CPC分类号: B29C39/405 , B29C33/70 , B29C37/005 , B29C45/0025 , B29C45/4421
摘要: When molding of a heat-curable resin such as unsaturated polyester resin and the like is conducted by means of the casting method, concavities in the molded product generated as a result of the curing shrinkage of this resin are prevented. A central core member comprising ABS resin or the like is disposed in advance within mold, a heat-curable resin liquid is injected thereinto, and heated, and at this time, an amount of expansion in the volume of central core member is caused which corresponds to the amount of volume shrinkage resulting from curing of the heat-curable resin, and the expansion of the central core member is synchronized with the curing shrinkage of the heat-curable resin.
摘要翻译: 当通过流延法进行诸如不饱和聚酯树脂等热固性树脂的模塑时,可以防止由于该树脂的固化收缩而产生的模制品中的凹凸。 包括ABS树脂等的中心芯部件预先设置在模具内,将热固性树脂液体注入其中并进行加热,此时,引起中心芯体的体积膨胀量 与由该固化性树脂固化而产生的体积收缩量相对应,并且中心芯体的膨胀与热固性树脂的固化收缩同步。
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公开(公告)号:US5676938A
公开(公告)日:1997-10-14
申请号:US462548
申请日:1995-06-05
申请人: Hiroshi Kimura , Yutaka Horie , Yoshiyuki Sato
发明人: Hiroshi Kimura , Yutaka Horie , Yoshiyuki Sato
IPC分类号: A61K8/58 , A61K8/891 , A61K8/892 , A61Q1/06 , A61Q3/00 , A61Q5/02 , A61Q5/12 , A61Q15/00 , A61Q19/00 , A61Q19/10 , A61K7/00 , A61K7/07
CPC分类号: A61K8/892 , A61K8/585 , A61Q19/00 , A61Q1/02 , A61Q1/06 , A61Q1/14 , A61Q15/00 , A61Q17/04 , A61Q19/10 , A61Q3/02 , A61Q5/02 , A61Q5/06 , A61Q5/12
摘要: A cosmetic composition comprising a silicone resin comprising from 50 to 99 mol % of R.sup.1 Si(O).sub.1.5 units wherein R.sup.1 represents a substituted or unsubstituted monovalent hydrocarbon group and from 1 to 50 mol % of (R.sup.2).sub.3 Si(O).sub.0.5 units wherein R.sup.2 represents a substituted or unsubstituted monovalent hydrocarbon group, sum of the R.sup.1 Si(O).sub.0.5 units and the (R.sup.2).sub.3 Si(O).sub.0.5 units being 100 mol %.
摘要翻译: 一种化妆品组合物,其包含含有50至99摩尔%的R 1 Si(O)1.5单元的硅氧烷树脂,其中R 1表示取代或未取代的单价烃基和1至50摩尔%的(R2)3Si(O)0.5单元,其中R2 表示取代或未取代的单价烃基,R1Si(O)0.5单元和(R2)3Si(O)0.5单元之和为100摩尔%。
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