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    Monosaccharide Derivatives as Anti-Inflammatory and/or Anti-Cancer Agents
    4.
    发明申请
    Monosaccharide Derivatives as Anti-Inflammatory and/or Anti-Cancer Agents 审中-公开
    单糖衍生物作为抗炎和/或抗癌剂

    公开(公告)号：US20090048186A1

    公开(公告)日：2009-02-19

    申请号：US11912064

    申请日：2005-04-19

    申请人： Vishwajanani Jitendra Sattigeri ,  Sudershan K. Arora ,  Mohammad Salman ,  Venkata P. Palle ,  Ashis Mukherjee ,  Abhijit Ray ,  Raj Kumar Shirumalla

    发明人： Vishwajanani Jitendra Sattigeri ,  Sudershan K. Arora ,  Mohammad Salman ,  Venkata P. Palle ,  Ashis Mukherjee ,  Abhijit Ray ,  Raj Kumar Shirumalla

    IPC分类号： A61K31/7052 ,  C07H15/18 ,  A61K31/7034 ,  C07D493/04 ,  C07H17/02

    CPC分类号： C07H9/04 ,  C07H3/02 ,  C07H15/00

    摘要： The present invention relates to monosaccharide derivatives as anti-inflammatory agents. The compounds disorder herein can be useful for inhibition and prevention of inflammation and associated pathologies including inflammatory and autoimmune diseases such as bronchial asthma, rheumatoid arthritis, type I diabetes, multiple sclerosis, allograft rejection, psoriasis, inflammatory bowel disease, ulcerative colitis, acne, atherosclerosis, cancer, pruritis and allergic rhinitis. Pharmacological compositions containing compounds disclosed herein and the methods of treating bronchial asthma, chronic obstructive pulmonary disease, rheumatoid arthritis, multiple sclerosis, type I diabetes, psoriasis, allograft rejection, inflammatory bowel disease, ulcerative colitis, acne, atherosclerosis, cancer, pruritis, allergic rhinitis and other inflammatory and/or autoimmune disorders, using the compounds are also provided.

    摘要翻译： 本发明涉及作为抗炎剂的单糖衍生物。 本文中的化合物障碍可用于抑制和预防炎症和相关病理，包括炎症和自身免疫性疾病，例如支气管哮喘，类风湿性关节炎，I型糖尿病，多发性硬化，同种异体移植排斥，牛皮癣，炎性肠病，溃疡性结肠炎，痤疮， 动脉粥样硬化，癌症，瘙痒和过敏性鼻炎。 含有本文公开的化合物的药理学组合物和治疗支气管哮喘，慢性阻塞性肺病，类风湿性关节炎，多发性硬化，I型糖尿病，牛皮癣，同种异体移植排斥，炎性肠病，溃疡性结肠炎，痤疮，动脉粥样硬化，癌症，瘙痒，过敏性 还提供使用该化合物的鼻炎和其它炎性和/或自身免疫性疾病。

    MONOSACCHARIDE DERIVATIVES
    5.
    发明申请
    MONOSACCHARIDE DERIVATIVES 审中-公开
    单糖衍生物

    公开(公告)号：US20090221515A1

    公开(公告)日：2009-09-03

    申请号：US11574465

    申请日：2005-08-31

    申请人： Viswajanani Jitendra Sattigeri ,  Sudershan K. Arora ,  Venkata P. Palle ,  Mohammad Salman ,  Abhijit Ray ,  Raj Kumar Shirumalla ,  Abdul Rehaman Abdul Rauf

    发明人： Viswajanani Jitendra Sattigeri ,  Sudershan K. Arora ,  Venkata P. Palle ,  Mohammad Salman ,  Abhijit Ray ,  Raj Kumar Shirumalla ,  Abdul Rehaman Abdul Rauf

    IPC分类号： A61K31/7008 ,  C07H5/04

    CPC分类号： C07H15/18

    摘要： The present invention relates to monosaccharide derivatives as anti-inflammatory agents. The compounds disclosed herein can be useful for inhibition and prevention of inflammation and associated pathologies, including inflammatory and autoimmune diseases such as bronchial asthma, rheumatoid arthritis, type I diabetes, multiple sclerosis, allograft rejection, psoriasis, inflammatory bowel disease, ulcerative colitis, acne, atherosclerosis, cancer, pruritis or allergic rhinitis. Pharmacological compositions containing the compounds of the present invention and the methods of treating bronchial asthma, chronic obstructive pulmonary disease, rheumatoid arthritis, multiple sclerosis, type I diabetes, psoriasis, allograft rejection, inflammatory bowel disease, ulcerative colitis, acne, atherosclerosis, cancer, pruritis, allergic rhinitis and other inflammatory and/or autoimmune disorders, using the compounds are also provided.

    摘要翻译： 本发明涉及作为抗炎剂的单糖衍生物。 本文公开的化合物可用于抑制和预防炎症和相关病理学，包括炎症和自身免疫性疾病如支气管哮喘，类风湿性关节炎，I型糖尿病，多发性硬化，同种异体移植排斥，牛皮癣，炎性肠病，溃疡性结肠炎，痤疮 ，动脉粥样硬化，癌症，瘙痒症或过敏性鼻炎。 包含本发明化合物的药物组合物，治疗支气管哮喘，慢性阻塞性肺病，类风湿性关节炎，多发性硬化，I型糖尿病，牛皮癣，同种异体移植排斥，炎性肠病，溃疡性结肠炎，痤疮，动脉粥样硬化，癌症， 还提供了使用该化合物的瘙痒症，过敏性鼻炎和其它炎性和/或自身免疫性疾病。

    Muscarinic Receptor Antagonists
    10.
    发明申请
    Muscarinic Receptor Antagonists 审中-公开
    毒蕈碱受体拮抗剂

    公开(公告)号：US20080255188A1

    公开(公告)日：2008-10-16

    申请号：US11995433

    申请日：2006-07-11

    申请人： Naresh Kumar ,  Mohammad Salman ,  Kirandeep Kaur ,  Anita Chugh ,  Sandeep Sinha

    发明人： Naresh Kumar ,  Mohammad Salman ,  Kirandeep Kaur ,  Anita Chugh ,  Sandeep Sinha

    IPC分类号： A61K31/472 ,  C07D217/26

    CPC分类号： C07D471/08

    摘要： This present invention generally relates to muscarinic receptor antagonists of Formula (I), which are useful, among other uses, for the treatment of various diseases of the respiratory, urinary and gastrointestinal systems mediated through muscarinic receptors. The invention also relates to the process for the preparation of disclosed compounds, pharmaceutical compositions containing the disclosed compounds, and the methods for treating diseases mediated through muscarinic receptors.

    摘要翻译： 本发明一般涉及式（I）的毒蕈碱受体拮抗剂，其可用于治疗通过毒蕈碱受体介导的呼吸，泌尿和胃肠系统的各种疾病。 本发明还涉及制备所公开的化合物的方法，含有所公开的化合物的药物组合物，以及用于治疗通过毒蕈碱受体介导的疾病的方法。