公开(公告)号：US09555382B2

公开(公告)日：2017-01-31

申请号：US13261941

申请日：2013-02-18

申请人： NATIONAL RESEARCH COUNCIL OF CANADA

发明人： Liviu Clime ,  Teodor Veres

IPC分类号： B01F13/00 ,  B81B7/00 ,  B01F5/06 ,  B01F15/02

CPC分类号： B01F13/0059 ,  B01F5/0606 ,  B01F13/0069 ,  B01F15/0233 ,  B81B7/00

摘要： A centrifugal microfluidic device having a microfluidic mixing element with a microfluidic mixing chamber in which at least two flows emerging from channels into the chamber at separate places are redirected to land at substantially the same place on a mixing surface provides efficient mixing of two or more fluids in the chamber.

摘要翻译： 一种具有微流体混合元件的离心微流体装置，其具有微流体混合室，其中至少两个在分开的位置处从通道流入室中的流被重定向到在混合表面上的基本相同的位置上的平台提供了两种或多种流体的有效混合 在房间里。

公开(公告)号：US11071985B2

公开(公告)日：2021-07-27

申请号：US15313961

申请日：2015-05-26

申请人： National Research Council of Canada

发明人： Liviu Clime ,  Teodor Veres ,  Keith Morton

IPC分类号： B01L9/00 ,  B04B5/04 ,  G01N35/00

摘要： A centrifugal microfluidic chip mounting, kit and method include a swivel joint permitting a chip to rotate about an axis of the chip in a plane swept by a centrifuge, and a force applicator for controlling an angle of the swivel and for applying a force in proportion to a rotational rate of the centrifuge. The mounting includes: a blade part (18) that couples to, or defines, a blade (10) of a centrifuge at a radial distance from a centrifuge axis (12); a chip part (20) that holds the chip at an orientation having a normal not perpendicular to the axis; a one degree of freedom (DoF) joint (16) between the blade part and the chip part; and a force applicator (28) which bears on the chip part at a fixed set of one or more points, which do not surround, and are not surrounded by, the joint.

公开(公告)号：US10702868B2

公开(公告)日：2020-07-07

申请号：US15124236

申请日：2015-03-04

申请人： NATIONAL RESEARCH COUNCIL OF CANADA

发明人： Teodor Veres ,  Daniel Brassard ,  Liviu Clime ,  Francois Normandin

IPC分类号： B01L3/00 ,  G01N35/00 ,  B01F9/00 ,  B01F13/00 ,  B01F13/02 ,  B01F15/00 ,  B01F15/02 ,  G05D7/06 ,  G01N35/04 ,  B01L7/00

摘要： A technique is provided for incorporating pneumatic control in centrifugal microfluidics. The technique involves providing a chip controller that has pressurized fluid supply lines for coupling one or more pressurized chambers of the controller with ports of a microfluidic chip. At least part of the chip controller is mounted to a centrifuge for rotation with the chip. A flow control device is provided in each supply line for selectively controlling the pressurized fluid supply, and is electrically controlled. Bubble mixing, on and off-chip valving, and switching are demonstrated.