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公开(公告)号：US20120046457A1
公开(公告)日：2012-02-23
申请号：US13282921
申请日：2011-10-27
CPC分类号： C07D251/16 , C07H13/12 , C07H15/04 , C07H19/12
摘要： The present application relates to processes for the preparation and purification of decitabine structurally represented by formula (I): and to processes for the preparation of a crystalline form of decitabine.
摘要翻译： 本申请涉及由式（I）结构表示的地西他滨的制备和纯化方法：以及制备地西他滨结晶形式的方法。
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公开(公告)号：US20110028518A1
公开(公告)日：2011-02-03
申请号：US12921873
申请日：2009-03-18
申请人： Naveen Kumar Kolla , Nagaraju Manne , Srinivas Gangula , Udaykumar Neelam , Anitha Naredla , Sudhakar Reddy Baddam , Sumeet Vishwasrao Patil , Arjunkumar Tummala , Subbareddy Peddireddy , Sachin Gulabrao Shinde , Ashok Sigala , Satish Varma Mudunuru , Madhu Kiran Tummidi
发明人： Naveen Kumar Kolla , Nagaraju Manne , Srinivas Gangula , Udaykumar Neelam , Anitha Naredla , Sudhakar Reddy Baddam , Sumeet Vishwasrao Patil , Arjunkumar Tummala , Subbareddy Peddireddy , Sachin Gulabrao Shinde , Ashok Sigala , Satish Varma Mudunuru , Madhu Kiran Tummidi
IPC分类号： A61K31/4439 , C07D401/12 , A61P1/04
CPC分类号： C07D401/12 , A61K9/1635 , A61K9/1652 , A61K47/6951 , B82Y5/00
摘要： Processes for the preparation of dexlansoprazole, an amorphous form of dexlansoprazole, a solid dispersion of amorphous dexlansoprazole and a pharmaceutically acceptable carrier, and processes for their preparation. Also provided are crystalline compounds 2-[(R)-[(4-chloro-3-methyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole and 2-[(R)-[(4-nitro-3-methyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole, and methods for their preparation.
摘要翻译： 右兰索拉唑，无效形式的右兰索拉唑，无定形右兰索拉唑的固体分散体和药学上可接受的载体的方法及其制备方法。 还提供了结晶化合物2 - [（R） - [（4-氯-3-甲基-2-吡啶基）甲基]亚磺酰基] -1H-苯并咪唑和2 - [（R） - [（4-硝基-3- 甲基-2-吡啶基）甲基]亚磺酰基] -1H-苯并咪唑及其制备方法。
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公开(公告)号：US20100298327A1
公开(公告)日：2010-11-25
申请号：US12294986
申请日：2007-03-29
申请人： Vijayavitthal Thippannachar Mathad , Pravinchandra Jayantilal Vankawala , Raviram Chandrasekhar Elati , Prabhakar Macharla , Srinivas Gangula , Naveen Kumar Kolla , Ravi Kumar Komareddy , Surya Narayana Devarkonda , Subbareddy Peddireddy
发明人： Vijayavitthal Thippannachar Mathad , Pravinchandra Jayantilal Vankawala , Raviram Chandrasekhar Elati , Prabhakar Macharla , Srinivas Gangula , Naveen Kumar Kolla , Ravi Kumar Komareddy , Surya Narayana Devarkonda , Subbareddy Peddireddy
IPC分类号： A61K31/5377 , C07D413/06 , A61P1/08
CPC分类号： C07D413/06
摘要： Intimate mixtures of aprepitant crystalline Form I and crystalline Form II, having specific Hweight ratios of the forms.
摘要翻译： 形式I和结晶形式II的紧密混合物，其形式具有特定的重量比。
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公开(公告)号：US08217039B2
公开(公告)日：2012-07-10
申请号：US12294986
申请日：2007-03-29
申请人： Vijayavitthal Thippannachar Mathad , Pravinchandra Jayantilal Vankawala , Raviram Chandrasekhar Elati , Prabhakar Macharla , Srinivas Gangula , Naveen Kumar Kolla , Ravi Kumar Komareddy , Surya Narayana Devarkonda , Subbareddy Peddireddy
发明人： Vijayavitthal Thippannachar Mathad , Pravinchandra Jayantilal Vankawala , Raviram Chandrasekhar Elati , Prabhakar Macharla , Srinivas Gangula , Naveen Kumar Kolla , Ravi Kumar Komareddy , Surya Narayana Devarkonda , Subbareddy Peddireddy
IPC分类号： A61K31/53 , C07D417/06
CPC分类号： C07D413/06
摘要： Intimate mixtures of aprepitant crystalline Form I and crystalline Form II, having specific weight ratios of the forms.
摘要翻译： 形式I和结晶形式II的紧密混合物，具有比例的形式。
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公开(公告)号：US08133994B2
公开(公告)日：2012-03-13
申请号：US12089077
申请日：2006-10-06
申请人： Pravinchandra Jayantilal Vankawala , Ravi Ram Chandrasekhar Elati , Naveen Kumar Kolla , Subrahmanyeswara Rao Chlamala , Srinivas Gangula
发明人： Pravinchandra Jayantilal Vankawala , Ravi Ram Chandrasekhar Elati , Naveen Kumar Kolla , Subrahmanyeswara Rao Chlamala , Srinivas Gangula
IPC分类号： C07D265/32
CPC分类号： C07D265/32 , C07D413/06
摘要： A process for preparing aprepitant.
摘要翻译： 制备aprepitant的过程。
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公开(公告)号：US20110094321A1
公开(公告)日：2011-04-28
申请号：US12089077
申请日：2006-10-06
申请人： Pravinchandra Jayantilal Vankawala , Ravi Ram Chandrasekhar Elati , Naveen Kumar Kolla , Subrahmanyeswara Rao Chlamala , Srinivas Gangula
发明人： Pravinchandra Jayantilal Vankawala , Ravi Ram Chandrasekhar Elati , Naveen Kumar Kolla , Subrahmanyeswara Rao Chlamala , Srinivas Gangula
IPC分类号： G01N33/00 , C07D265/32
CPC分类号： C07D265/32 , C07D413/06
摘要： A process for preparing aprepitant.
摘要翻译： 制备aprepitant的过程。
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公开(公告)号：US20090048336A1
公开(公告)日：2009-02-19
申请号：US12193201
申请日：2008-08-18
IPC分类号： A61K31/343 , C07D307/87 , A61P25/24
CPC分类号： C07D307/87
摘要： Escitalopram oxalate powders having definite particle size distribution parameters, processes for preparing the powders, and solid pharmaceutical formulations containing the powders.
摘要翻译： 具有确定的粒度分布参数的草酮草铵盐粉末，制备粉末的方法和含有粉末的固体药物制剂。
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公开(公告)号：US20080214535A1
公开(公告)日：2008-09-04
申请号：US11997203
申请日：2006-07-31
申请人： Vijayavitthal Thippannachar Mathad , Pravinchandra Vankawala Jayantilal , Chandrasekhar Ravi Ram Elati , Subrahmanyeswara Rao Chlamala , Naveen Kumar Kolla , Srinivas Gangula , Srirami Reddy Kikkuru , Srinivasan Neti , Raveendra Reddy Chinta
发明人： Vijayavitthal Thippannachar Mathad , Pravinchandra Vankawala Jayantilal , Chandrasekhar Ravi Ram Elati , Subrahmanyeswara Rao Chlamala , Naveen Kumar Kolla , Srinivas Gangula , Srirami Reddy Kikkuru , Srinivasan Neti , Raveendra Reddy Chinta
IPC分类号： A61K31/5377
CPC分类号： A61K31/496 , A61K9/146 , A61K47/32
摘要： A coprecipitate comprising amorphous aprepitant and a pharmaceutically acceptable carrier is prepared by rapidly removing solvent from a solution containing aprepitant and the carrier.
摘要翻译： 通过从含有阿维地丁和载体的溶液中快速除去溶剂来制备包含无定形阿拉曲珠和药学上可接受的载体的共沉淀物。
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公开(公告)号：US20070249563A1
公开(公告)日：2007-10-25
申请号：US11737783
申请日：2007-04-20
申请人： Apurba Bhattacharya , Vijayabhaskar Bolugoddu , Pravinchandra Vankawala , Chandrasekhar Elati , Srinivas Gangula , Amarnath Lekkala , Ramakrishna Mallemula , Anitha Naredla , Ashok Sigala
发明人： Apurba Bhattacharya , Vijayabhaskar Bolugoddu , Pravinchandra Vankawala , Chandrasekhar Elati , Srinivas Gangula , Amarnath Lekkala , Ramakrishna Mallemula , Anitha Naredla , Ashok Sigala
IPC分类号： A61K31/675 , C07F9/6506
CPC分类号： C07D233/74 , C07F9/6506
摘要： Processes for preparing fosphenytoin.
摘要翻译： 制备芬太尼的方法
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公开(公告)号：US20090018351A1
公开(公告)日：2009-01-15
申请号：US10595794
申请日：2004-11-12
申请人： Venkataraman Sundaram , Vijayavithai Thippannachar Mathad , Pravinachandra Jayanthilal Venkavala , Chandrashekar Ravirama Elati , Naveenkumar Kolla , Shanmugam Govindan , Subrahmanyeshwara Rao Chalamala , Srinivas Gangula
发明人： Venkataraman Sundaram , Vijayavithai Thippannachar Mathad , Pravinachandra Jayanthilal Venkavala , Chandrashekar Ravirama Elati , Naveenkumar Kolla , Shanmugam Govindan , Subrahmanyeshwara Rao Chalamala , Srinivas Gangula
IPC分类号： C07D307/78
CPC分类号： C07D307/87
摘要： The present invention relates to a process for preparing enantiomerically enriched citalopram via methylating enantiomerically enriched didesmethylcitalopram, which is prepared by directly resolving racemic didesmethylcitalopram using a chiral acid.
摘要翻译： 本发明涉及通过甲基化对映异构体富集的二甲基西酞普兰来制备对映体富集的西酞普兰的方法，其通过使用手性酸直接拆分外消旋二甲基西酞普兰来制备。
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