Fitting for fluidic coupling in a chromatography system

    公开(公告)号:US11782032B2

    公开(公告)日:2023-10-10

    申请号:US16991687

    申请日:2020-08-12

    IPC分类号: G01N30/60 F16L19/02

    摘要: A fitting for fluidic coupling in a chromatography system includes a compression screw including an axial bore, a threaded portion, and a drive end, a tube assembly including a tube sleeve and an inner tube disposed through the sleeve, the tube sleeve and the inner tube each extending to an endface of the tube assembly, the tube sleeve including an outer surface, a seal body extending between a first endface and a second endface, the first endface abutting the endface of the tube assembly, the seal body including an outer surface, and a collar secured to the outer surface of the tube sleeve and the outer surface of the seal body. Other Fittings, Methods of manufacture of fittings, and methods of fluidic coupling are further disclosed.

    Manifold Connection Assembly
    7.
    发明申请

    公开(公告)号:US20170268704A1

    公开(公告)日:2017-09-21

    申请号:US15588408

    申请日:2017-05-05

    摘要: A manifold assembly has a manifold and can be located between a block and a plate, and serve as a stator for a valve or other component. The manifold, block or plate can have a plurality of ports either integral thereto or removably connected thereto, with the ports adapted to receive and sealingly engage with a tube having an inner tube layer, an outer tube layer, a sleeve, a tip portion, and a nut. Each of the nut, sleeve, inner and outer tubing layers, and tip portion have a passageway therethrough, with at least the passageways in the sleeve, tip portion, outer tube layer, and nut adapted to allow the inner tube layer to pass therethrough or extend over the inner layer. The ends of the tip portion and inner layer together can define a substantially flat surface which can form a seal in a flat-bottomed port of the manifold, block, or plate, which can be used in a component in an analytical instrument system, including for example a liquid chromatography system. The nut, tube, ferrule, and transfer tube or liner tube may comprise biocompatible materials. In addition, the nut may have a slot, such as a slot adapted to allow the tube and the nut to be easily and quickly separated or to allow a portion of the tube to be easily and quickly inserted in the nut.

    COLUMN ATTACHMENT DEVICE
    8.
    发明申请

    公开(公告)号:US20170120251A1

    公开(公告)日:2017-05-04

    申请号:US15311584

    申请日:2014-05-16

    IPC分类号: B01L9/00 B01D53/02 G01N30/60

    摘要: A ferrule 10 is pressed by a pressing plate 35, and the ferrule 10 is thereby sandwiched and fixed between a ferrule receiving part 20 and ferrule pressing part 30. The pressing plate 35 is displaced by a displacing mechanism 350, whereby the pressing plate 35 is switched between a contacting state in which the pressing plate 35 is in contact with the ferrule 10 and a non-contacting state in which the pressing plate 35 is not in contact with the ferrule 10 and the ferrule 10 can pass thorough the inside of the ferrule pressing part 30. By displacement of the pressing plate 35 to the non-contacting state, the ferrule pressing part 30 can be extracted from the ferrule 10 side, and the ferrule pressing part 30 can therefore be removed from a column 2 in a state in which the ferrule 10 is attached in a swaged fashion.