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公开(公告)号:US11566012B2
公开(公告)日:2023-01-31
申请号:US17038690
申请日:2020-09-30
申请人: Neoculi Pty Ltd.
IPC分类号: A61K31/44 , C07C47/565 , C07C251/24 , C07D333/58 , A61K31/155 , A61K31/381 , C07C281/18 , C07D239/50 , C07D295/135 , A61K31/17 , A61K31/341 , A61K31/4045 , A61K31/4192 , A61K31/498 , C07C211/29 , C07D209/14 , C07D239/48 , C07D241/20 , C07D249/14 , C07D251/54 , C07D307/56 , C07D311/58 , C07D401/14 , A61K9/00 , A61K31/404 , A61K31/496 , A61K31/505 , A61K45/06 , C07C335/40 , C07D209/08
摘要: The invention provides compounds of Formula (I), and their use in methods for treating or preventing a protozoan infection in a subject using a compound of Formula (I). The invention also provides the use of a compound of Formula (I) in the manufacture of a medicament for the treatment of a protozoan infection in a subject. The invention further provides a medical device when used in a method of treating or preventing a protozoan infection in a subject and to a medical device comprising the composition of the invention.
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公开(公告)号:US20200290990A1
公开(公告)日:2020-09-17
申请号:US16892661
申请日:2020-06-04
申请人: Neoculi Pty Ltd.
IPC分类号: C07D333/58 , A61K31/155 , A61K31/381 , C07C281/18 , C07D239/50 , C07D295/135 , A61K31/17 , A61K31/341 , A61K31/4045 , A61K31/4192 , A61K31/44 , A61K31/498 , C07C47/565 , C07C211/29 , C07C251/24 , C07D209/14 , C07D239/48 , C07D241/20 , C07D249/14 , C07D251/54 , C07D307/56 , C07D311/58 , C07D401/14 , A61K9/00 , A61K31/404 , A61K31/496 , A61K31/505 , A61K45/06 , C07C335/40 , C07D209/08
摘要: The invention provides compounds of Formula (I), and their use in methods for treating or preventing a protozoan infection in a subject using a compound of Formula (I). The invention also provides the use of a compound of Formula (I) in the manufacture of a medicament for the treatment of a protozoan infection in a subject. The invention further provides a medical device when used in a method of treating or preventing a protozoan infection in a subject and to a medical device comprising the composition of the invention.
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公开(公告)号:US10562880B2
公开(公告)日:2020-02-18
申请号:US16505049
申请日:2019-07-08
申请人: Neoculi Pty Ltd.
IPC分类号: C07D333/50 , A61K9/00 , A61K31/155 , A61K31/341 , A61K31/44 , A61K31/505 , C07D333/58 , A61K45/06 , C07D209/08 , C07C335/40 , A61K31/496 , C07C47/565 , C07D209/14 , C07D239/50 , C07C211/29 , C07D401/14 , C07C251/24 , C07D241/20 , C07C281/18 , A61K31/498 , A61K31/4192 , A61K31/4045 , A61K31/381 , C07D307/56 , C07D295/135 , C07D251/54 , C07D249/14 , C07D239/48 , C07D311/58 , A61K31/404 , A61K31/17
摘要: The invention provides compounds of Formula (I), and their use in methods for treating or preventing a protozoan infection in a subject using a compound of Formula (I). The invention also provides the use of a compound of Formula (I) in the manufacture of a medicament for the treatment of a protozoan infection in a subject. The invention further provides a medical device when used in a method of treating or preventing a protozoan infection in a subject and to a medical device comprising the composition of the invention.
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公开(公告)号:US20190084941A1
公开(公告)日:2019-03-21
申请号:US16146894
申请日:2018-09-28
申请人: Neoculi Pty Ltd.
发明人: Stephen Page , Sanjay Garg , Martine Keenan , Adam McCluskey , Andrew Stevens
IPC分类号: C07D239/50 , C07D251/48 , A61K45/06 , C07D251/54 , C07C281/16 , C07F9/6512 , C07C281/18 , C07C281/08 , A01N47/44 , A01N43/54 , C07D295/125 , C07D209/14 , A61K31/381 , A61K31/155 , C07D333/58 , C07D307/56 , C07D213/53 , C07D209/40 , C07D251/66 , C07D215/12 , C07C337/08 , C07C323/45 , C07D239/48 , A61K31/14 , A61K31/17 , A61K31/175 , A61K31/404 , A61K31/505
CPC分类号: C07D239/50 , A01N43/54 , A01N47/44 , A61K31/14 , A61K31/155 , A61K31/17 , A61K31/175 , A61K31/381 , A61K31/404 , A61K31/505 , A61K45/06 , C07C281/08 , C07C281/16 , C07C281/18 , C07C323/45 , C07C337/08 , C07D209/14 , C07D209/40 , C07D213/53 , C07D215/12 , C07D239/48 , C07D251/48 , C07D251/54 , C07D251/66 , C07D295/125 , C07D307/56 , C07D333/58 , C07F9/6512 , A61K2300/00
摘要: The invention provides compounds of Formula I, and methods of treating or preventing a bacterial infection in a subject using a compound of Formula I. The invention also provides the use of a compound of Formula I in the manufacture of a medicament for the treatment of a bacterial infection in a subject. The invention further provides a medical device when used in a method of treating or preventing a bacterial infection in a subject and to a medical device comprising the composition of the invention.
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公开(公告)号:US10752606B2
公开(公告)日:2020-08-25
申请号:US16699476
申请日:2019-11-29
申请人: Neoculi Pty Ltd.
IPC分类号: A61K31/155 , A61K31/505 , C07C251/24 , C07D239/48 , C07D333/58 , A61K31/381 , C07C281/18 , C07D239/50 , C07D295/135 , A61K31/17 , A61K31/341 , A61K31/4045 , A61K31/4192 , A61K31/44 , A61K31/498 , C07C47/565 , C07C211/29 , C07D209/14 , C07D241/20 , C07D249/14 , C07D251/54 , C07D307/56 , C07D311/58 , C07D401/14 , A61K9/00 , A61K31/404 , A61K31/496 , A61K45/06 , C07C335/40 , C07D209/08
摘要: The invention provides compounds of Formula (I), and their use in methods for treating or preventing a protozoan infection in a subject using a compound of Formula (I). The invention also provides the use of a compound of Formula (I) in the manufacture of a medicament for the treatment of a protozoan infection in a subject. The invention further provides a medical device when used in a method of treating or preventing a protozoan infection in a subject and to a medical device comprising the composition of the invention.
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公开(公告)号:US10253002B2
公开(公告)日:2019-04-09
申请号:US14888306
申请日:2014-05-01
申请人: Neoculi Pty Ltd.
发明人: Stephen Page , Sanjay Garg , Martine Keenan , Adam McCluskey , Andrew Stevens
IPC分类号: C07D239/50 , C07D239/48 , C07D251/48 , C07D251/54 , C07D251/66 , C07D281/16 , C07C281/18 , C07C281/16 , C07D333/58 , A61K31/155 , A61K31/381 , C07D209/14 , C07D295/125 , C07C281/08 , A61K45/06 , A61K31/14 , A61K31/17 , A61K31/175 , A61K31/404 , A61K31/505 , C07C323/45 , C07C337/08 , C07D215/12 , C07D209/40 , C07D213/53 , C07D307/56 , A01N43/54 , A01N47/44 , C07F9/6512
摘要: The invention provides compounds of Formula I, and methods of treating or preventing a bacterial infection in a subject using a compound of Formula I. The invention also provides the use of a compound of Formula I in the manufacture of a medicament for the treatment of a bacterial infection in a subject. The invention further provides a medical device when used in a method of treating or preventing a bacterial infection in a subject and to a medical device comprising the composition of the invention.
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公开(公告)号:US10392363B2
公开(公告)日:2019-08-27
申请号:US15508266
申请日:2015-08-28
申请人: Neoculi Pty Ltd.
IPC分类号: A61K31/155 , A61K31/341 , A61K31/404 , A61K31/44 , C07C211/29 , C07C281/18 , C07D333/58 , A61K31/381 , A61K31/4045 , A61K31/4192 , A61K31/498 , C07D241/20 , C07C251/24 , C07D401/14 , C07D239/50 , C07D209/14 , C07C47/565 , C07D311/58 , C07D239/48 , C07D249/14 , C07D251/54 , C07D295/135 , C07D307/56 , A61K9/00 , A61K31/496 , A61K31/505 , A61K45/06 , C07C335/40 , C07D209/08 , A61K31/17
摘要: The invention provides compounds of Formula (I), and their use in methods for treating or preventing a protozoan infection in a subject using a compound of Formula (I). The invention also provides the use of a compound of Formula (I) in the manufacture of a medicament for the treatment of a protozoan infection in a subject. The invention further provides a medical device when used in a method of treating or preventing a protozoan infection in a subject and to a medical device comprising the composition of the invention.
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公开(公告)号:US10370341B2
公开(公告)日:2019-08-06
申请号:US16146894
申请日:2018-09-28
申请人: Neoculi Pty Ltd.
发明人: Stephen Page , Sanjay Garg , Martine Keenan , Adam McCluskey , Andrew Stevens
IPC分类号: A61K31/155 , A61K31/381 , A61K31/14 , A61K31/17 , A61K31/175 , A61K31/404 , A61K31/505 , C07D239/50 , C07D251/54 , C07D239/48 , C07D251/48 , C07C281/16 , C07D333/58 , C07D209/14 , C07D295/125 , C07C281/08 , C07C281/18 , A61K45/06 , C07C323/45 , C07C337/08 , C07D215/12 , C07D251/66 , C07D209/40 , C07D213/53 , C07D307/56 , A01N43/54 , A01N47/44 , C07F9/6512
摘要: The invention provides compounds of Formula I, and methods of treating or preventing a bacterial infection in a subject using a compound of Formula I. The invention also provides the use of a compound of Formula I in the manufacture of a medicament for the treatment of a bacterial infection in a subject. The invention further provides a medical device when used in a method of treating or preventing a bacterial infection in a subject and to a medical device comprising the composition of the invention.
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公开(公告)号:US09775818B2
公开(公告)日:2017-10-03
申请号:US15363523
申请日:2016-11-29
申请人: Neoculi Pty Ltd.
发明人: Stephen Page , Sanjay Garg
IPC分类号: A61K31/155 , A61K45/06 , A61K31/43 , A61K9/00
CPC分类号: A61K31/155 , A61K9/0014 , A61K9/0053 , A61K31/43 , A61K45/06 , A61K2300/00
摘要: The invention comprises methods for treating and preventing a bacterial infection in a subject, methods for preparing a medicament for use in treating and preventing a bacterial infection in a subject, and pharmaceutical and veterinary antibacterial compositions when used therein.
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公开(公告)号:US20160058717A1
公开(公告)日:2016-03-03
申请号:US14888289
申请日:2014-05-01
申请人: NEOCULI PTY LTD
发明人: Stephen Page , Sanjay Garg
IPC分类号: A61K31/155 , A61K45/06
CPC分类号: A61K31/155 , A61K9/0014 , A61K9/0053 , A61K31/43 , A61K45/06 , A61K2300/00
摘要: The invention comprises methods for treating and preventing a bacterial infection in a subject, methods for preparing a medicament for use in treating and preventing a bacterial infection in a subject, and pharmaceutical and veterinary antibacterial compositions when used therein.
摘要翻译: 本发明包括治疗和预防受试者细菌感染的方法,制备用于治疗和预防受试者细菌感染的药物的方法,以及当其中使用时的药用和兽用抗菌组合物。
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