利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

12 条记录 (耗时 0.043 秒)

    SYSTEMS, DEVICES AND METHODS USING PHASE-AMPLITUDE COUPLING MEASURES IN IMPLANTABLE MEDICAL DEVICES
    1.
    发明申请
    SYSTEMS, DEVICES AND METHODS USING PHASE-AMPLITUDE COUPLING MEASURES IN IMPLANTABLE MEDICAL DEVICES 有权

    公开(公告)号：US20210186407A1

    公开(公告)日：2021-06-24

    申请号：US17191175

    申请日：2021-03-03

    申请人： NeuroPace, Inc.

    发明人： Sharanya ARCOT DESAI ,  Thomas K. TCHENG ,  Stephen T. ARCHER

    IPC分类号： A61B5/374 ,  A61B5/00 ,  A61N1/372 ,  A61M5/172 ,  A61N1/36 ,  A61B5/291 ,  A61B5/316

    摘要： A sensor of an implantable medical device senses electrical activity of the brain. A data analyzer of the device monitors an electrographic signal corresponding to the electrical activity of the sensed brain signal, and processes the brain signal to obtain a measure of phase-amplitude coupling. For a selected portion of the electrographic signal, the data analyzer detects first features and second features of the electrographic signal. The first features represent oscillations in a low frequency range, while the second features represent oscillations in a frequency range higher than the low frequency range. For example, the low frequency range may correspond to theta frequency and the higher frequency range may correspond to gamma frequency. The data analyzer determines a measure of phase-amplitude coupling between oscillations in the low frequency range and oscillations in the higher frequency range based on occurrences of second features which coincide with first features.

    MEASURING CURRENT DURING DELIVERY OF VOLTAGE REGULATED STIMULATION TO A PATIENT
    3.
    发明申请
    MEASURING CURRENT DURING DELIVERY OF VOLTAGE REGULATED STIMULATION TO A PATIENT 有权
    在电压调节期间测量电流到患者

    公开(公告)号：US20160339254A1

    公开(公告)日：2016-11-24

    申请号：US15225719

    申请日：2016-08-01

    申请人： NeuroPace, Inc.

    发明人： Stephen T. ARCHER

    IPC分类号： A61N1/36 ,  A61N1/372

    CPC分类号： A61N1/36153 ,  A61N1/37264 ,  A61N1/37282

    摘要： A system and method for estimating the current delivered to a patient during voltage-regulated electrical stimulation therapy by an implantable medical device includes calculating a total charge delivered and a peak current delivered and the time at which the peak current was delivered using a proxy for the current delivered to the patient and a component such as a current controlled oscillator, the output of which is proportional to the current proxy together with memory for storing values relating to the output proportional to the current proxy. The stored values also may be used to construct a waveform approximating the current delivered to the patient during a therapy of voltage-regulated stimulation. The system and method may be implemented in an active implantable medical device such as an implantable neurostimulator.

    摘要翻译： 用于估计在通过可植入医疗装置进行的电压调节电刺激治疗期间递送给患者的电流的系统和方法包括计算所递送的总电荷和所递送的峰值电流以及使用代用于 传递到患者的电流和诸如电流控制振荡器的组件，其输出与当前代理成比例，与用于存储与当前代理成比例的输出相关的值的存储器成比例。 所存储的值也可用于构建在电压调节刺激的治疗期间接近递送给患者的电流的波形。 该系统和方法可以在诸如可植入神经刺激器的有源可植入医疗装置中实现。

    ANATOMICALLY COMPLIANT ANTENNA FOR IMPLANTABLE MEDICAL DEVICE
    4.
    发明申请
    ANATOMICALLY COMPLIANT ANTENNA FOR IMPLANTABLE MEDICAL DEVICE 有权
    用于可植入医疗器械的合适的天线

    公开(公告)号：US20140266933A1

    公开(公告)日：2014-09-18

    申请号：US14205051

    申请日：2014-03-11

    申请人： NeuroPace, Inc.

    发明人： Dean ANDERSEN ,  Stephen T. ARCHER ,  John Dunagan PEARSON

    IPC分类号： H01Q1/27

    CPC分类号： H01Q1/273 ,  A61N1/37229 ,  H01Q1/36 ,  H01Q1/40 ,  H01Q7/00

    摘要： A flexible antenna is associated with an active implantable medical device to facilitate communication between the implantable medical device and an external component in the outside world via, for example, long range or far field telemetry. The flexibility of the antenna allows it to conform to the shape of the location at which it is situated, such as on the cranial bone of a patient for an antenna associated with a cranially implanted medical device. The conformability of the antenna helps to maintain the antenna in the desired shape and to maintain it in the desired location relative to implantable medical device and the patient and improves patient comfort.

    摘要翻译： 柔性天线与有源可植入医疗装置相关联，以通过例如远距离或远场遥测来促进可植入医疗装置与外界的外部部件之间的通信。 天线的灵活性允许其符合其所在位置的形状，例如与患有颅骨植入的医疗装置相关联的天线的患者的颅骨上。 天线的一致性有助于将天线保持在期望的形状并且将其保持在相对于可植入医疗装置和患者的期望位置并改善患者的舒适度。

    CURRENT MANAGEMENT SYSTEM FOR A STIMULATION OUTPUT STAGE OF AN IMPLANTABLE NEUROSTIMULATION SYSTEM
    10.
    发明申请
    CURRENT MANAGEMENT SYSTEM FOR A STIMULATION OUTPUT STAGE OF AN IMPLANTABLE NEUROSTIMULATION SYSTEM 有权
    可植入神经系统刺激输出阶段的电流管理系统

    公开(公告)号：US20170001018A1

    公开(公告)日：2017-01-05

    申请号：US15261822

    申请日：2016-09-09

    申请人： NeuroPace, Inc.

    发明人： Stephen T. ARCHER

    IPC分类号： A61N1/36

    CPC分类号： A61N1/36157 ,  A61N1/36125

    摘要： A current management system for use in the stimulation output stage of a neurostimulation system can be programmed to steer different amounts of current through different stimulation electrodes to vary how strongly the tissue adjacent each electrode is stimulated during a particular programmed stimulation episode. An stimulation electrode drive circuit associated with each electrode that is available for stimulation allows independent control of the flow of current through that electrode. A reference electrode is provided in the circuit to source or sink current as necessary to balance the currents going into and out of the patient, so that no stimulation electrode is required to serve that purpose. More specifically, by configuring the circuit to maintain a constant potential at the reference electrode (e.g., a potential that is approximately half way between a top and bottom voltage rail), the reference electrode will source or sink currents as necessary to cause the net current flow into the patient to be equal to the net current flowing out of the patient, thus satisfying Kirchhoff's current law.

    摘要翻译： 用于神经刺激系统的刺激输出阶段的当前管理系统可以被编程为通过不同的刺激电极引导不同量的电流，以改变在特定的程序化刺激发作期间刺激相邻每个电极的组织的强度。 与可用于刺激的每个电极相关联的刺激电极驱动电路允许独立地控制通过该电极的电流。 在电路中提供参考电极以根据需要来源或吸收电流以平衡进入和流出患者的电流，使得不需要刺激电极来满足该目的。 更具体地，通过将​​电路配置为在参考电极处保持恒定电位（例如，在顶部和底部电压轨道之间的大约一半的电位），参考电极将根据需要来源或吸收电流以使净电流 流入患者等于流出患者的净流量，从而满足基尔霍夫现行的法律。