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公开(公告)号:US06995239B1
公开(公告)日:2006-02-07
申请号:US09275549
申请日:1999-03-24
IPC分类号: C07K14/38
摘要: The present invention provides a method for producing desired proteins or chemicals in fungal host cells which comprise modulating the nucleic acid encoding proteins associated with hyphal growth. The amino acid and nucleic acid sequence of hbrA is provided.
摘要翻译: 本发明提供了一种在真菌宿主细胞中产生所需蛋白质或化学物质的方法,其包括调节与菌丝生长相关的蛋白质的核酸。 提供hbrA的氨基酸和核酸序列。
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公开(公告)号:US07189538B2
公开(公告)日:2007-03-13
申请号:US10778804
申请日:2004-02-12
IPC分类号: C12P21/02
摘要: The present invention provides a method for producing desired proteins or chemicals in fungal host cells, which comprise modulating the nucleic acid encoding proteins associated with hyphal growth. The amino acid and nucleic acid sequences of hbrA and hbrB are provided.
摘要翻译: 本发明提供了一种在真菌宿主细胞中产生所需蛋白质或化学物质的方法,其包括调节与菌丝生长相关的蛋白质的核酸。 提供hbrA和hbrB的氨基酸和核酸序列。
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公开(公告)号:US07745189B2
公开(公告)日:2010-06-29
申请号:US12184211
申请日:2008-07-31
申请人: Ali R. Akin , Elizabeth A. Bodie , Shirley M. Burrow , Nigel Dunn-Coleman , Geoffrey Turner , Michael Ward
发明人: Ali R. Akin , Elizabeth A. Bodie , Shirley M. Burrow , Nigel Dunn-Coleman , Geoffrey Turner , Michael Ward
CPC分类号: C12N9/1205 , C07K14/38 , C12N15/80 , C12P21/02
摘要: The present invention generally relates to hyphal growth in fungi and in particular describes the modulation of genes associated with hyphal growth in filamentous fungi. The present invention provides methods and systems for the production of proteins and/or chemicals from filamentous fungi which comprise modulation of genes associated with hyphal growth. Specifically, the present invention is directed to a full length cotA gene, its gene product and methods of use.
摘要翻译: 本发明通常涉及真菌中的菌丝生长,并且具体地描述了丝状真菌中菌丝生长相关基因的调节。 本发明提供了用于从丝状真菌生产蛋白质和/或化学物质的方法和系统,其包括调节与菌丝生长相关的基因。 具体地,本发明涉及全长cotA基因,其基因产物和使用方法。
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公开(公告)号:US08304221B2
公开(公告)日:2012-11-06
申请号:US12816362
申请日:2010-06-15
申请人: Ali R. Akin , Elizabeth A. Bodie , Shirley M. Burrow , Nigel Dunn-Coleman , Geoffrey Turner , Michael Ward
发明人: Ali R. Akin , Elizabeth A. Bodie , Shirley M. Burrow , Nigel Dunn-Coleman , Geoffrey Turner , Michael Ward
CPC分类号: C12N9/1205 , C07K14/38 , C12N15/80 , C12P21/02
摘要: The present invention generally relates to hyphal growth in fungi and in particular describes the modulation of genes associated with hyphal growth in filamentous fungi. The present invention provides methods and systems for the production of proteins and/or chemicals from filamentous fungi which comprise modulation of genes associated with hyphal growth. Specifically, the present invention is directed to a full length cotA gene, its gene product and methods of use.
摘要翻译: 本发明通常涉及真菌中的菌丝生长,并且具体地描述了丝状真菌中菌丝生长相关基因的调节。 本发明提供了用于从丝状真菌生产蛋白质和/或化学物质的方法和系统,其包括调节与菌丝生长相关的基因。 具体地,本发明涉及全长cotA基因,其基因产物和使用方法。
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公开(公告)号:US20070264693A1
公开(公告)日:2007-11-15
申请号:US11642192
申请日:2006-12-20
摘要: The present invention provides a method for producing desired proteins or chemicals in fungal host cells, which comprise modulating the nucleic acid encoding proteins associated with hyphal growth. The amino acid and nucleic acid sequences of hbrA and hbrB are provided.
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公开(公告)号:US20090093039A1
公开(公告)日:2009-04-09
申请号:US12184211
申请日:2008-07-31
申请人: Ali R. Akin , Elizabeth A. Bodie , Shirley Burrow , Nigel Dunn-Coleman , Geoffrey Turner , Michael Ward
发明人: Ali R. Akin , Elizabeth A. Bodie , Shirley Burrow , Nigel Dunn-Coleman , Geoffrey Turner , Michael Ward
CPC分类号: C12N9/1205 , C07K14/38 , C12N15/80 , C12P21/02
摘要: The present invention generally relates to hyphal growth in fungi and in particular describes the modulation of genes associated with hyphal growth in filamentous fungi. The present invention provides methods and systems for the production of proteins and/or chemicals from filamentous fungi which comprise modulation of genes associated with hyphal growth. Specifically, the present invention is directed to a full length cotA gene, its gene product and methods of use.
摘要翻译: 本发明通常涉及真菌中的菌丝生长,并且具体地描述了丝状真菌中菌丝生长相关基因的调节。 本发明提供了用于从丝状真菌生产蛋白质和/或化学物质的方法和系统,其包括调节与菌丝生长相关的基因。 具体地,本发明涉及全长cotA基因,其基因产物和使用方法。
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公开(公告)号:US07425450B2
公开(公告)日:2008-09-16
申请号:US11113837
申请日:2005-04-25
申请人: Ali R. Akin , Elizabeth A. Bodie , Shirley M. Burrow , Nigel Dunn-Coleman , Geoffrey Turner , Michael Ward
发明人: Ali R. Akin , Elizabeth A. Bodie , Shirley M. Burrow , Nigel Dunn-Coleman , Geoffrey Turner , Michael Ward
CPC分类号: C12N9/1205 , C07K14/38 , C12N15/80 , C12P21/02
摘要: The present invention generally relates to hyphal growth in fungi and in particular describes the modulation of genes associated with hyphal growth in filamentous fungi. The present invention provides methods and systems for the production of proteins and/or chemicals from filamentous fungi which comprise modulation of genes associated with hyphal growth. Specifically, the present invention is directed to a full length cotA gene, its gene product and methods of use.
摘要翻译: 本发明通常涉及真菌中的菌丝生长,并且具体地描述了丝状真菌中菌丝生长相关基因的调节。 本发明提供了用于从丝状真菌生产蛋白质和/或化学物质的方法和系统,其包括调节与菌丝生长相关的基因。 具体地,本发明涉及全长cotA基因,其基因产物和使用方法。
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公开(公告)号:US20050255513A1
公开(公告)日:2005-11-17
申请号:US11113837
申请日:2005-04-25
申请人: Ali Akin , Elizabeth Bodie , Shirley Burrow , Nigel Dunn-Coleman , Geoffrey Turner , Michael Ward
发明人: Ali Akin , Elizabeth Bodie , Shirley Burrow , Nigel Dunn-Coleman , Geoffrey Turner , Michael Ward
IPC分类号: C07K14/38 , C12N9/12 , C12N15/80 , C12P21/02 , C12Q1/68 , C07H21/04 , C07K14/39 , C12N1/18 , C12N15/74 , C12P21/06
CPC分类号: C12N9/1205 , C07K14/38 , C12N15/80 , C12P21/02
摘要: The present invention generally relates to hyphal growth in fungi and in particular describes the modulation of genes associated with hyphal growth in filamentous fungi. The present invention provides methods and systems for the production of proteins and/or chemicals from filamentous fungi which comprise modulation of genes associated with hyphal growth. Specifically, the present invention is directed to a full length cotA gene, its gene product and methods of use.
摘要翻译: 本发明通常涉及真菌中的菌丝生长,并且具体地描述了丝状真菌中菌丝生长相关基因的调节。 本发明提供了用于从丝状真菌生产蛋白质和/或化学物质的方法和系统,其包括调节与菌丝生长相关的基因。 具体地,本发明涉及全长cotA基因,其基因产物和使用方法。
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公开(公告)号:US20110059507A1
公开(公告)日:2011-03-10
申请号:US12816362
申请日:2010-06-15
申请人: Ali R. Akin , Elizabeth A. Bodie , Shirley M. Burrow , Nigel Dunn-Coleman , Geoffrey Turner , Michael Ward
发明人: Ali R. Akin , Elizabeth A. Bodie , Shirley M. Burrow , Nigel Dunn-Coleman , Geoffrey Turner , Michael Ward
CPC分类号: C12N9/1205 , C07K14/38 , C12N15/80 , C12P21/02
摘要: The present invention generally relates to hyphal growth in fungi and in particular describes the modulation of genes associated with hyphal growth in filamentous fungi. The present invention provides methods and systems for the production of proteins and/or chemicals from filamentous fungi which comprise modulation of genes associated with hyphal growth. Specifically, the present invention is directed to a full length cotA gene, its gene product and methods of use.
摘要翻译: 本发明通常涉及真菌中的菌丝生长,并且具体地描述了丝状真菌中菌丝生长相关基因的调节。 本发明提供了用于从丝状真菌生产蛋白质和/或化学物质的方法和系统,其包括调节与菌丝生长相关的基因。 具体地,本发明涉及全长cotA基因,其基因产物和使用方法。
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公开(公告)号:US06936449B2
公开(公告)日:2005-08-30
申请号:US10100252
申请日:2002-03-14
申请人: Ali R. Akin , Elizabeth A. Bodie , Shirley Burrow , Nigel Dunn-Coleman , Geoffrey Turner , Michael Ward
发明人: Ali R. Akin , Elizabeth A. Bodie , Shirley Burrow , Nigel Dunn-Coleman , Geoffrey Turner , Michael Ward
IPC分类号: C07K14/38 , C12N9/12 , C12N15/80 , C12P21/02 , C12N9/10 , C07H21/04 , C07K1/00 , C12N1/12 , C12N1/14
CPC分类号: C12N9/1205 , C07K14/38 , C12N15/80 , C12P21/02
摘要: The present invention generally relates to hyphal growth in fungi and in particular describes the modulation of genes associated with hyphal growth in filamentous fungi. The present invention provides methods and systems for the production of proteins and/or chemicals from filamentous fungi which comprise modulation of genes associated with hyphal growth. Specifically, the present invention is directed to a full length cotA gene, its gene product and methods of use.
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