1,4 Substituted Pyrazolopyrimidines as Kinase Inhibitors
    2.
    发明申请
    1,4 Substituted Pyrazolopyrimidines as Kinase Inhibitors 审中-公开
    1,4取代吡唑并嘧啶作为激酶抑制剂

    公开(公告)号:US20080096868A1

    公开(公告)日:2008-04-24

    申请号:US11718730

    申请日:2005-11-10

    CPC分类号: C07D487/04

    摘要: The invention relates to 1,4-substituted pyrazolopyrimidine compounds of the formula I, pharmaceuticals comprising a 1,4-substituted pyrazolopyrimidine compound, the use of a 1,4-substituted pyrazolopyrimidine compound in the treatment or the use thereof in the manufacture of a pharmaceutical formulation for the treatment of a disease that depends on inadequate activity of a protein kinase, methods of treatment comprising administering a 1,4-substituted pyrazolopyrimidine compound, methods for the manufacture of a novel compound of that class, and novel intermediates and partial steps for their synthesis.

    摘要翻译: 本发明涉及式I的1,4-取代吡唑并嘧啶化合物,包含1,4-取代的吡唑并嘧啶化合物的药物,1,4-取代的吡唑并嘧啶化合物在其制备中的用途和用途 用于治疗依赖于蛋白激酶活性不足的疾病的药物制剂,包括施用1,4-取代的吡唑并嘧啶化合物的方法,制备该类新化合物的方法,以及新的中间体和部分步骤 为他们的合成。