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    Measurement of a blood flow rate in hemodialysis shunts
    1.
    发明申请
    Measurement of a blood flow rate in hemodialysis shunts 失效
    测量血液透析分流中的血流量

    公开(公告)号：US20050178732A1

    公开(公告)日：2005-08-18

    申请号：US11104947

    申请日：2005-04-13

    申请人： Nikolai Krivitski ,  David MacGibbon

    发明人： Nikolai Krivitski ,  David MacGibbon

    IPC分类号： A61B5/0275 ,  A61M1/16 ,  A61M1/36 ,  C02F1/00 ,  G01F1/00

    CPC分类号： A61M1/3653 ,  A61B5/0275 ,  A61M1/16 ,  A61M1/3655 ,  A61M1/3658 ,  A61M1/3663 ,  A61M1/3669 ,  A61M1/367

    摘要： The measurement of blood flow in a dialysis shunt is obtained by injection of an indicator material into a venous line leading from dialysis equipment to the shunt. The blood flow in an arterial line leading from the shunt at a location downstream of the venous line to the dialysis equipment is monitored by an arterial line sensor for the presence of the indicator material. A detector connected to the sensor provides a dilution curve in response to the presence of the indicator material and the blood flow in the shunt is calculated from the area under the dilution curve. The locations of the arterial and venous lines in the shunt can be reversed to obtain a measurement of blood recirculation from the venous line into the arterial line.

    摘要翻译： 通过将指示剂材料注射到从透析设备引导到分流器的静脉管线中，可以测量透析分流器中的血流量。 通过动脉线传感器监测从静脉线下游位置到分离设备的分流处的动脉线中的血液流动，以指示物质的存在。 连接到传感器的检测器响应于指示剂材料的存在而提供稀释曲线，并且根据稀释曲线下的面积计算分流器中的血流量。 分流器中的动脉和静脉线的位置可以反转，以获得从静脉线进入动脉线的血液再循环的测量。

    Method and apparatus to measure blood flow in hemodialysis shunts
    2.
    发明申请
    Method and apparatus to measure blood flow in hemodialysis shunts 失效
    测量血液透析分流血流量的方法和装置

    公开(公告)号：US20050051496A1

    公开(公告)日：2005-03-10

    申请号：US10871319

    申请日：2004-06-18

    申请人： Nikolai Krivitski ,  David MacGibbon

    发明人： Nikolai Krivitski ,  David MacGibbon

    IPC分类号： A61B5/0275 ,  A61M1/16 ,  A61M1/36 ,  A61B5/026 ,  A61M31/00

    CPC分类号： A61M1/3653 ,  A61B5/0275 ,  A61M1/16 ,  A61M1/3655 ,  A61M1/3658 ,  A61M1/3663 ,  A61M1/3669 ,  A61M1/367

    摘要： The measurement of blood flow in a dialysis shunt is obtained by injection of an indicator material into a venous line leading from dialysis equipment to the shunt. The blood flow in an arterial line leading from the shunt at a location downstream of the venous line to the dialysis equipment is monitored by an arterial line sensor for the presence of the indicator material. A detector connected to the sensor provides a dilution curve in response to the presence of the indicator material and the blood flow in the shunt is calculated from the area under the dilution curve. The locations of the arterial and venous lines in the shunt can be reversed to obtain a measurement of blood recirculation from the venous line into the arterial line.

    摘要翻译： 通过将指示剂材料注射到从透析设备引导到分流器的静脉管线中，可以测量透析分流器中的血流量。 通过动脉线传感器监测从静脉线下游位置到分离设备的分流处的动脉线中的血液流动，以指示物质的存在。 连接到传感器的检测器响应于指示剂材料的存在而提供稀释曲线，并且根据稀释曲线下的面积计算分流器中的血流量。 分流器中的动脉和静脉线的位置可以反转，以获得从静脉线进入动脉线的血液再循环的测量。

    System and method for diverting flow to facilitate measurement of system parameters
    3.
    发明申请
    System and method for diverting flow to facilitate measurement of system parameters 有权
    用于转移流量的系统和方法，以方便系统参数的测量

    公开(公告)号：US20080275354A1

    公开(公告)日：2008-11-06

    申请号：US12082692

    申请日：2008-04-11

    申请人： Naveen Thuramalla ,  Nikolai Krivitski ,  Mark Alsberge

    发明人： Naveen Thuramalla ,  Nikolai Krivitski ,  Mark Alsberge

    IPC分类号： A61B5/029 ,  A61M1/00

    CPC分类号： A61M1/3621 ,  A61B5/02028 ,  A61B5/0215 ,  A61B5/02152 ,  A61B5/0275 ,  A61M1/3609 ,  A61M1/367

    摘要： A method and various devices are disclosed that facilitates the measurement of hemodynamic parameters by injection of an indicator in an indicator dilution technique using an extracorporeal circuit connected to a patient. Specifically, the invention deals with problems caused by the spike in pressure in an extracorporeal line that result from the injection of a bolus. The method and various devices provide for diversion of blood during an indictor injection process and then return of the diverted blood back into the system after the injection is completed. The variations of the invention use diversion lines, accommodating cases and other devices that are designed to accumulate blood displaced during injection and then returning the blood to the extracorporeal circuit after injection.

    摘要翻译： 公开了一种方法和各种装置，其通过使用连接到患者的体外电路在指示剂稀释技术中注射指示器来促进血液动力学参数的测量。 具体地，本发明涉及由于注射大剂量导致的体外线中的压力尖峰所引起的问题。 该方法和各种装置在指示注射过程中提供血液转移，然后在注射完成后将转移的血液返回到系统中。 本发明的变型使用引流线，容纳壳体和其他装置，其被设计成在注射期间积聚血液置换，然后在注射后将血液返回到体外电路。

    Method and Apparatus to Determine an Initial Flow Rate in a Conduit
    4.
    发明申请
    Method and Apparatus to Determine an Initial Flow Rate in a Conduit 有权
    确定管道初始流速的方法和装置

    公开(公告)号：US20060243061A1

    公开(公告)日：2006-11-02

    申请号：US11456751

    申请日：2006-07-11

    申请人： Nikolai Krivitski ,  Cornelis Drost

    发明人： Nikolai Krivitski ,  Cornelis Drost

    IPC分类号： G01F1/708

    CPC分类号： A61B5/027 ,  A61B5/0215 ,  A61B5/0255 ,  A61B5/026 ,  A61B5/0275 ,  A61B5/6852 ,  A61M25/00 ,  G01F1/34 ,  G01F1/66 ,  G01F1/704 ,  G01F1/708 ,  G01F25/0007

    摘要： A method and apparatus for determining an initial flow rate in a conduit is disclosed. A known change is made to the flow to be measured, resulting changes (or values corresponding to these changes), or relative changes in the flow to be measured are monitored and the initial flow in the conduit is calculated from the value of the known change and monitored changes. Devices to practice the method include catheters having one or two sensors and one or two sites for introducing the volume change.

    摘要翻译： 公开了一种用于确定导管中初始流速的方法和装置。 对要测量的流量进行已知的变化，监测所得到的变化（或对应于这些变化的值）或待测量流量的相对变化，并根据已知变化的值计算导管中的初始流量 并监测变化。 实施该方法的装置包括具有一个或两个传感器的导管和用于引入体积变化的一个或两个位置。

    Method and Apparatus to Determine an Initial Flow Rate in a Conduit
    5.
    发明申请
    Method and Apparatus to Determine an Initial Flow Rate in a Conduit 有权
    确定管道初始流速的方法和装置

    公开(公告)号：US20070137296A1

    公开(公告)日：2007-06-21

    申请号：US11674448

    申请日：2007-02-13

    申请人： Nikolai Krivitski ,  Cornelis Drost

    发明人： Nikolai Krivitski ,  Cornelis Drost

    IPC分类号： G01F7/00

    CPC分类号： A61B5/027 ,  A61B5/0215 ,  A61B5/0255 ,  A61B5/026 ,  A61B5/0275 ,  A61B5/6852 ,  A61M25/00 ,  G01F1/34 ,  G01F1/66 ,  G01F1/704 ,  G01F1/708 ,  G01F25/0007

    摘要： A method and apparatus for determining an initial flow rate in a conduit is disclosed. A known change is made to the flow to be measured, resulting changes (or values corresponding to these changes), or relative changes in the flow to be measured are monitored and the initial flow in the conduit is calculated from the value of the known change and monitored changes. Devices to practice the method include catheters having one or two sensors and one or two sites for introducing the volume change.

    摘要翻译： 公开了一种用于确定导管中初始流速的方法和装置。 对要测量的流量进行已知的变化，监测所得到的变化（或对应于这些变化的值）或待测量流量的相对变化，并根据已知变化的值计算导管中的初始流量 并监测变化。 实施该方法的装置包括具有一个或两个传感器的导管和用于引入体积变化的一个或两个位置。

    Method and apparatus for measuring cardiac output via an extracorporeal cardiopulmonary support circuit
    6.
    发明申请
    Method and apparatus for measuring cardiac output via an extracorporeal cardiopulmonary support circuit 有权
    通过体外心肺支持电路测量心输出量的方法和装置

    公开(公告)号：US20060052715A1

    公开(公告)日：2006-03-09

    申请号：US10937191

    申请日：2004-09-09

    申请人： Nikolai Krivitski

    发明人： Nikolai Krivitski

    IPC分类号： A61B5/0275

    CPC分类号： A61B5/0275

    摘要： A method and apparatus for determining cardiac output in conjunction with flow through an extracorporeal circuit, wherein flow through an arterial line of the extracorporeal circuit is temporarily reversed and an indicator is passed through the cardiopulmonary circuit. A dilution curve is measured in the arterial line of the extracorporeal circuit during the reversed flow, and cardiac output is determined corresponding to the measured dilution curve.

    摘要翻译： 一种用于通过体外循环流动测定心输出量的方法和装置，其中通过体外循环的动脉线的流动暂时反转，并且指示器通过心肺回路。 在逆流期间在体外循环的动脉线中测量稀释曲线，并且根据测量的稀释曲线确定心输出量。

    METHOD FOR MEASURING CARDIAC OUTPUT VIA AN EXTRACORPOREAL CARDIOPULMONARY SUPPORT CIRCUIT
    8.
    发明申请
    METHOD FOR MEASURING CARDIAC OUTPUT VIA AN EXTRACORPOREAL CARDIOPULMONARY SUPPORT CIRCUIT 有权
    通过超声心动图支持电路测量心脏输出的方法

    公开(公告)号：US20080033314A1

    公开(公告)日：2008-02-07

    申请号：US11781536

    申请日：2007-07-23

    申请人： Nikolai Krivitski

    发明人： Nikolai Krivitski

    IPC分类号： A61B5/028

    CPC分类号： A61B5/0275

    摘要： A method for determining cardiac output in conjunction with flow through an extracorporeal circuit, wherein flow through an arterial line of the extracorporeal circuit is temporarily reversed and an indicator is passed through the cardiopulmonary circuit. A dilution curve is measured in the arterial line of the extracorporeal circuit during the reversed flow, and cardiac output is determined corresponding to the measured dilution curve.

    摘要翻译： 一种用于通过体外循环流动测定心输出量的方法，其中通过体外循环的动脉线的流动被暂时反转，并且指示器通过心肺回路。 在逆流期间在体外循环的动脉线中测量稀释曲线，并且根据测量的稀释曲线确定心输出量。