公开(公告)号：US20090043102A1

公开(公告)日：2009-02-12

申请号：US12063316

申请日：2006-08-02

申请人： Nils Bottke ,  Andrea Haunert

发明人： Nils Bottke ,  Andrea Haunert

IPC分类号： C07D213/62

CPC分类号： C07D213/30

摘要： A process for preparing heteroaromatic alcohols by catalytically hydrogenating heteroaromatic carboxylic acids or esters thereof by hydrogenating with hydrogen in the presence of a ruthenium-phosphine complex in an organic solvent.

摘要翻译： 通过在有机溶剂中在钌 - 膦配合物的存在下用氢气氢化杂芳族羧酸或其酯来制备杂芳族醇的方法。

公开(公告)号：US07601861B2

公开(公告)日：2009-10-13

申请号：US10577321

申请日：2004-10-29

申请人： Nils Bottke ,  Regina Benfer ,  Marco Bosch ,  Thomas Narbeshuber ,  Ulrich Steinbrenner ,  Juergen Stephan

发明人： Nils Bottke ,  Regina Benfer ,  Marco Bosch ,  Thomas Narbeshuber ,  Ulrich Steinbrenner ,  Juergen Stephan

IPC分类号： C07C309/31

CPC分类号： C11D1/22 ,  C07C2/66 ,  C07C2529/18 ,  C07C2529/70 ,  C07C15/107

摘要： In a process for preparing alkylaryl compounds by reacting a C10-14-monoolefin mixture with an aromatic hydrocarbon in the presence of an alkylation catalyst to form alkyl aromatic compounds and if appropriate subsequently sulfonating and neutralizing the resulting alkylaryl compounds, in the C10-14-monoolefins, on average, more than 0% and up to 100% of methyl branches are present in the longest carbon chain and fewer than 50% of the methyl branches are in the 2-, 3- and 4-position, calculated starting from the chain ends of the longest carbon chain.

摘要翻译： 在烷基芳基化合物存在下，通过使C10-14-单烯烃混合物与芳族烃反应制备烷基芳基化合物的方法形成烷基芳香族化合物，如果合适，则随后磺化和中和得到的烷基芳基化合物，在C10-14- 平均来说，最长碳链中存在大于0％和高达100％的甲基支链的单烯烃，并且少于50％的甲基支链位于2-，3-和4-位，从 最长碳链的链端。

公开(公告)号：US20080110763A1

公开(公告)日：2008-05-15

申请号：US11908506

申请日：2006-03-23

申请人： Ingo Richter ,  Hermann Putter ,  Ulrich Griesbach ,  Nils Bottke

发明人： Ingo Richter ,  Hermann Putter ,  Ulrich Griesbach ,  Nils Bottke

IPC分类号： C25D3/62 ,  C07D307/02

CPC分类号： C07D307/32 ,  C07D307/88 ,  C07D307/89 ,  C25B3/02

摘要： A process for the preparation of 2,5-dihydrofuran derivatives substituted in the 3- or 4-position, which in the 2- or in the 5-position or at both positions each carry a C1- to C6-alkoxy radical (DHF-alkoxy derivatives 1), or 1,1,4,4-tetraalkoxy-but-2-ene derivatives substituted in the 3- or 4-position, from 2-butene-1 ,4-diol derivatives of the general formula (I) in which the radicals R1 and R2 independently of one another are hydrogen, C1- to C6-alkyl, C6- to C12-aryl or C5- to C12-cycloalkylene orR1 and R2, together with the double bond to which they are bonded, form a C6- to C12-aryl radical or a mono- or polyunsaturated C5- to C12-cycloalkyl radical,orfrom their mixture with 2,5-dihydrofuran derivatives substituted in the 3- position or 4-position, which in the 2- or in the 5-position carry a C1- to C6-alkoxy radical, by electro-chemical oxidation in the presence of a C1- to C6-monoalkyl alcohol.

摘要翻译： 制备在3-或4-位取代的2,5-二氢呋喃衍生物的方法，其中2-或5-位或两个位置各自携带C 1 - 至C 6 - 烷氧基（DHF-烷氧基衍生物1）或在3-或4-位取代的1,1,4,4-四烷氧基 - 丁-2-烯衍生物，2 其中基团R 1和R 2彼此独立的通式（I）的1-丁烯-1,4-二醇衍生物是氢，C 1 -C 6烷基， 1〜C 6 - 烷基，C 6 - 至C 12 - 芳基或C 5〜 > - > C 12 - 亚环烷基或R 1和R 2与它们所键合的双键一起形成C < C 6 -C 12 - C 12 - 芳基或单不饱和C 5〜C 12 - 环烷基 ，或它们与3-或4-位取代的2,5-二氢呋喃衍生物的混合物，其在2-或5-位上携带C 1 H 通过在C 1 -C 6 - C 6 - 单烷基醇存在下的电化学氧化反应生成C 6〜C 6 - 烷氧基 。

公开(公告)号：US20100189623A1

公开(公告)日：2010-07-29

申请号：US12602504

申请日：2008-06-09

申请人： Veronika Wloka ,  Torsten Mattke ,  Carsten Knoesche ,  Daniel Breuninger ,  Nils Bottke

发明人： Veronika Wloka ,  Torsten Mattke ,  Carsten Knoesche ,  Daniel Breuninger ,  Nils Bottke

IPC分类号： C01B21/24 ,  C07C211/00 ,  C01B7/01 ,  C01B17/90

CPC分类号： C01B7/055 ,  B01D15/00 ,  B01J20/18 ,  C01B7/0718 ,  C07C209/78 ,  C07C211/50

摘要： The invention relates to a process for recovering acids from product streams of organic syntheses, which comprises the steps a) neutralization of the acid with a base, b) removal of the base by means of adsorption, c) recovery of the acid.

摘要翻译： 本发明涉及从有机合成产物流中回收酸的方法，其包括步骤a）用碱中和酸，b）通过吸附除去碱，c）回收酸。

公开(公告)号：US20090134066A1

公开(公告)日：2009-05-28

申请号：US11659422

申请日：2005-08-04

申请人： Nils Bottke ,  Michael Triller ,  Ulrich Muller ,  Rolf Pinkos ,  Thomas Heidemann

发明人： Nils Bottke ,  Michael Triller ,  Ulrich Muller ,  Rolf Pinkos ,  Thomas Heidemann

IPC分类号： C10G35/06 ,  C07C2/58

CPC分类号： C07C303/06 ,  C07C2/76 ,  C07C15/02 ,  C07C309/31

摘要： The present invention relates to a process for preparing alkylaromatics by reacting aromatic compounds with C1-C14-alkanes in the presence of a heterogeneous catalyst, which comprises using as the catalyst a crystalline, micro- and/or mesoporous solid comprising silicon and at least one father element selected from the group consisting of the transition metals and the main group elements gallium and tin, and activating said catalysts by a reducing pretreatment. Furthermore, the present invention relates to a process for preparing alkylarylsulfonates by sulfonating and neutralizing the alkyl aromatic compounds.

摘要翻译： 本发明涉及在非均相催化剂存在下使芳族化合物与C 1 -C 14烷烃反应制备烷基芳族化合物的方法，该方法包括使用包含硅和至少一种以上的硅的结晶，微孔和/或介孔固体作为催化剂 父元素选自过渡金属和主要元素镓和锡，并通过还原预处理活化所述催化剂。 此外，本发明涉及通过磺化和中和烷基芳族化合物来制备烷基芳基磺酸盐的方法。

公开(公告)号：US20060167323A1

公开(公告)日：2006-07-27

申请号：US10516922

申请日：2003-06-11

申请人： Michael Hesse ,  Stephan Schlitter ,  Holger Borchert ,  Markus Schubert ,  Markus Rosch ,  Nils Bottke ,  Rolf-Hartmuth Fischer ,  Alexander Weck ,  Gunther Windecker ,  Gunnar Heydrich

发明人： Michael Hesse ,  Stephan Schlitter ,  Holger Borchert ,  Markus Schubert ,  Markus Rosch ,  Nils Bottke ,  Rolf-Hartmuth Fischer ,  Alexander Weck ,  Gunther Windecker ,  Gunnar Heydrich

IPC分类号： C07C31/18

CPC分类号： C07C29/149 ,  C07C31/207

摘要： The present invention relates to a process for preparing optionally alkyl-substituted 1,4-butanediol by two-stage catalytic hydrogenation in the gas phase of C4-dicarboxylic acids and/or of derivatives thereof having the following steps: a) introducing a gas stream of a C4-dicarboxylic acid or of a derivative thereof at from 200 to 300° C. and from 2 to 60 bar into a first reactor and catalytically hydrogenating it in the gas phase to a product which contains mainly optionally alkyl-substituted γ-butyrolactone; b) removing succinic anhydride from the product obtained in step a), preferably to a residual level of from

摘要翻译： 本发明涉及通过在具有下列物质的C 4 - 二羧酸和/或其衍生物的气相中通过两阶段催化氢化制备任选的烷基取代的1,4-丁二醇的方法 步骤：a）将200-300℃和2-60巴的C 4-14二羧酸或其衍生物的气流引入第一反应器，并将其催化氢化为 气相至主要含有烷基取代的γ-丁内酯的产物; b）从步骤a）中获得的产物中除去琥珀酸酐，优选残留量为约0.3至0.2重量％; c）将步骤b）中获得的产物流在150℃至240℃的温度和15至100巴的压力下引入第二反应器，并将其在气相中催化氢化为任选的烷基 - 取代的1,4-丁二醇; d）从中间体，副产物和任何未转化的反应物中除去所需的产物; e）任选地将未转化的中间体再循环到一个或两个氢化步骤中，所述氢化步骤各自使用催化剂，所述催化剂包含95重量％，优选5至95重量％，特别是10至80重量％的CuO ，和> = 5重量％，优选5至95重量％，特别是20至90重量％的氧化载体，并且所述第二反应器具有比所述第一反应器更高的压力。

公开(公告)号：US07351311B2

公开(公告)日：2008-04-01

申请号：US10505774

申请日：2003-02-28

申请人： Gunther Windecker ,  Alexander Weck ,  Rolf-Hartmuth Fischer ,  Markus Rösch ,  Nils Bottke ,  Michael Hesse ,  Stephan Schlitter ,  Holger Borchert

发明人： Gunther Windecker ,  Alexander Weck ,  Rolf-Hartmuth Fischer ,  Markus Rösch ,  Nils Bottke ,  Michael Hesse ,  Stephan Schlitter ,  Holger Borchert

IPC分类号： B01D3/14 ,  C07D307/08

CPC分类号： B01D3/146 ,  C07D307/08 ,  Y10S203/20

摘要： Crude water-containing tetrahydrofuran is purified by passing the crude tetrahydrofuran through three distillation columns, withdrawing water from the bottom of the first column, recycling water-containing tetrahydrofuran from the top of the second column into the first column, passing a sidestream of the first column into the second column, recycling the bottom product of the third column into the first column, and withdrawing a distillate at the top of the first column. Additionally, a sidestream of the second column is passed into the third column and the purified tetrahydrofuran is recovered as the top product of the third column.

摘要翻译： 通过将粗四氢呋喃通过三个蒸馏塔，从第一塔的底部排出水，将含水四氢呋喃从第二塔的顶部再循环到第一塔中，将第一个塔 塔进入第二列，将第三塔的底部产物回收到第一塔中，并且抽出第一塔顶部的馏出物。 此外，将第二塔的侧流送入第三塔，回收纯化的四氢呋喃作为第三塔的顶部产物。

公开(公告)号：US07271299B2

公开(公告)日：2007-09-18

申请号：US10516922

申请日：2003-06-11

申请人： Michael Hesse ,  Stephan Schlitter ,  Holger Borchert ,  Markus Schubert ,  Markus Rösch ,  Nils Bottke ,  Rolf-Hartmuth Fischer ,  Alexander Weck ,  Gunther Windecker ,  Gunnar Heydrich

发明人： Michael Hesse ,  Stephan Schlitter ,  Holger Borchert ,  Markus Schubert ,  Markus Rösch ,  Nils Bottke ,  Rolf-Hartmuth Fischer ,  Alexander Weck ,  Gunther Windecker ,  Gunnar Heydrich

IPC分类号： C07C31/18

CPC分类号： C07C29/149 ,  C07C31/207

摘要： Optionally alkyl-substituted 1,4-butanediol is prepared from C4-dicarboxylic acids and/or of derivatives thereof by: a) a gas stream of the C4-dicarboxylic acid or the derivative thereof in a first reactor in the gas phase to obtain a product which contains mainly optionally alkyl-substituted γ-butyro-lactone; b) removing succinic anhydride from the product of step a); c) catalytically hydrogenating the product of step b) in a second reactor in the gas phase to obtain optionally alkyl-substituted 1,4-butanediol; d) removing the desired product from intermediates, by-products and any unconverted reactants; and e) optionally recycling unconverted intermediates into one or both hydrogenation stages. The catalysts employed in each of the hydrogenation stages comprise ≦95% by weight of CuO, and ≦5% by weight of an oxidic support, and the second reactor has a higher pressure than the first reactor.

摘要翻译： 任选地，烷基取代的1,4-丁二醇由C 4-14二羧酸和/或其衍生物通过以下方法制备：a）引入C 4 - 二羧酸或其衍生物在气相中的第一反应器中，以获得主要含有烷基取代的γ-丁内酯的产物; b）从步骤a）的产物中除去琥珀酸酐; c）在气相中的第二反应器中催化氢化步骤b）的产物以获得任选的烷基取代的1,4-丁二醇; d）从中间体，副产物和任何未转化的反应物中除去所需的产物; 和e）任选地将未转化的中间体再循环到一个或两个氢化阶段。 在每个氢化阶段中使用的催化剂包含<95重量％的CuO和<= 5重量％的氧化载体，并且第二反应器具有比第一反应器更高的压力。

公开(公告)号：US20070078075A1

公开(公告)日：2007-04-05

申请号：US10577321

申请日：2004-10-29

申请人： Nils Bottke ,  Regina Benfer ,  Marco Bosch ,  Thomas Narbeshuber ,  Ulrich Steinbrenner ,  Jurgen Stephan

发明人： Nils Bottke ,  Regina Benfer ,  Marco Bosch ,  Thomas Narbeshuber ,  Ulrich Steinbrenner ,  Jurgen Stephan

IPC分类号： C11D17/08 ,  C07C309/24

CPC分类号： C11D1/22 ,  C07C2/66 ,  C07C2529/18 ,  C07C2529/70 ,  C07C15/107

摘要： In a process for preparing alkylaryl compounds by reacting a C10-14-monoolefin mixture with an aromatic hydrocarbon in the presence of an alkylation catalyst to form alkyl aromatic compounds and if appropriate subsequently sulfonating and neutralizing the resulting alkylaryl compounds, in the C10-14-monoolefins, on average, more than 0% and up to 100% of methyl branches are present in the longest carbon chain and fewer than 50% of the methyl branches are in the 2-, 3- and 4-position, calculated starting from the chain ends of the longest carbon chain.

摘要翻译： 在烷基芳基化合物的存在下通过使C 10-14 - 单烯烃混合物与芳族烃反应制备烷基芳基化合物的方法，以形成烷基芳族化合物，并且如果合适，则随后磺化和中和所得的烷基芳基 在最长的碳链中存在C 10-14 - 单烯烃中的平均超过0％和高达100％的甲基支链的化合物，少于50％的甲基支链是 在2-，3-和4-位，从最长碳链的链端开始计算。

公开(公告)号：US07169958B2

公开(公告)日：2007-01-30

申请号：US10516923

申请日：2003-06-10

申请人： Michael Hesse ,  Stephan Schlitter ,  Holger Borchert ,  Markus Schubert ,  Markus Rösch ,  Nils Bottke ,  Rolf-Hartmuth Fischer ,  Alexander Weck ,  Gunther Windecker ,  Gunnar Heydrich

发明人： Michael Hesse ,  Stephan Schlitter ,  Holger Borchert ,  Markus Schubert ,  Markus Rösch ,  Nils Bottke ,  Rolf-Hartmuth Fischer ,  Alexander Weck ,  Gunther Windecker ,  Gunnar Heydrich

IPC分类号： C07C29/132 ,  C07C29/149 ,  C07C29/136 ,  C07C29/147

CPC分类号： C07C29/149 ,  C07C31/207

摘要： The present invention relates to a process for preparing optionally alkyl-substituted 1,4-butanediol by two-stage catalytic hydrogenation in the gas phase of C4-dicarboxylic acids and/or of derivatives thereof having the following steps: a) introducing a gas stream of a C4-dicarboxylic acid or of a derivative thereof at from 200 to 300° C. and from 2 to 60 bar into a first reactor and catalytically hydrogenating it to a product which contains mainly optionally alkyl-substituted γ-butyrolactone; b) converting the product stream into the liquid phase; c) introducing the product stream obtained in this way into a second reactor at a temperature of from 100° C. to 240° C. and a pressure of from 20 to 250 bar and catalytically hydrogenating it in the liquid phase to optionally alkyl-substituted 1,4-butanediol; d) removing the desired product from by-products and any unconverted reactants; e) optionally recycling unconverted intermediates into one or both hydrogenation stages, said hydrogenation stages both using a catalyst which comprises ≦95% by weight, preferably from 5 to 95% by weight, in particular from 10 to 80% by weight, of CuO, and ≧5% by weight, preferably from 5 to 95% by weight, in particular from 20 to 90% by weight, of a support, said second reactor having a higher pressure than said first reactor, and the product mixture removed from said first reactor being introduced without further purification into said second reactor.

摘要翻译： 本发明涉及通过在具有下列物质的C 4 - 二羧酸和/或其衍生物的气相中通过两阶段催化氢化制备任选的烷基取代的1,4-丁二醇的方法 步骤：a）将200-300℃和2-60巴的C 4-14二羧酸或其衍生物的气流引入第一反应器，并将其催化氢化至 主要含烷基取代的γ-丁内酯的产品; b）将产物流转化成液相; c）将以这种方式获得的产物流在100℃至240℃的温度和20至250巴的压力下引入第二反应器，并将其在液相中催化氢化为任选的烷基取代的 1,4-丁二醇 d）从副产物和任何未转化的反应物中除去所需的产物; e）任选地将未转化的中间体再循环到一个或两个氢化阶段中，所述氢化步骤均使用包含<= 95重量％，优选5至95重量％，特别是10至80重量％的CuO ，和> = 5重量％，优选5至95重量％，特别是20至90重量％的载体，所述第二反应器具有比所述第一反应器更高的压力，并将产物混合物从 所述第一反应器不经进一步纯化地引入所述第二反应器。