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1.发明授权Generation triple-targeting, chiral, broad-spectrum antimicrobial 7-substituted piperidino-quinolone carboxylic acid derivatives, their preparation, compositions and use as medicaments 失效产生三重靶向，手性，广谱抗微生物剂7-取代哌啶子基 - 喹诺酮羧酸衍生物，其制备，组合物和作为药物的用途公开(公告)号：US07626032B2
公开(公告)日：2009-12-01
申请号：US12150075
申请日：2008-04-24
申请人： Noel John De Souza , Mahesh Vithalbhai Patel , Prasad Keshav Deshpande , Shiv Kumar Agarwal , Kandepu Sreenivas , Sheela Chandrasekharan Nair , Yati Chugh , Milind Chintaman Shukla
发明人： Noel John De Souza , Mahesh Vithalbhai Patel , Prasad Keshav Deshpande , Shiv Kumar Agarwal , Kandepu Sreenivas , Sheela Chandrasekharan Nair , Yati Chugh , Milind Chintaman Shukla
IPC分类号： C07D211/56
CPC分类号： A61K31/47 , A61K45/06 , C07D215/233 , C07D401/04 , C07D401/14 , C07D413/12 , C07D455/04 , C07D471/04 , C07D471/08 , Y10S514/859
摘要： This invention relates to new generation triple-targeting, chiral, broad-spectrum antimicrobial 7-substituted piperidino-quinolone carboxylic acid derivatives, to their optical isomers, diastereomers or enantiomers, as well as pharmaceutically acceptable salts, hydrates, prodrugs, polymorphs and pseudopolymorphs thereof, to their preparation, to their compositions and to their use.
摘要翻译： 本发明涉及新一代三靶向，手性，广谱抗微生物7-取代的哌啶子基 - 喹诺酮羧酸衍生物，其旋光异构体，非对映异构体或对映异构体，以及其药学上可接受的盐，水合物，前药，多晶型物和假多晶型物 ，准备，组合和使用。
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2.发明授权Generation triple-targeting, chiral, broad-spectrum antimicrobial 7-substituted piperidino-quinolone carboxylic acid derivatives, their preparation, compositions and use as medicaments 失效产生三重靶向，手性，广谱抗微生物剂7-取代哌啶子基 - 喹诺酮羧酸衍生物，其制备，组合物和作为药物的用途公开(公告)号：US07393957B2
公开(公告)日：2008-07-01
申请号：US10945504
申请日：2004-09-20
申请人： Noel John De Souza , Mahesh Vithalbhai Patel , Prasad Keshav Deshpande , Shiv Kumar Agarwal , Kandepu Sreenivas , Sheela Chandrasekharan Nair , Yati Chugh , Milind Chintaman Shukla
发明人： Noel John De Souza , Mahesh Vithalbhai Patel , Prasad Keshav Deshpande , Shiv Kumar Agarwal , Kandepu Sreenivas , Sheela Chandrasekharan Nair , Yati Chugh , Milind Chintaman Shukla
IPC分类号： C07D215/38 , A61K31/47
CPC分类号： A61K31/47 , A61K45/06 , C07D215/233 , C07D401/04 , C07D401/14 , C07D413/12 , C07D455/04 , C07D471/04 , C07D471/08 , Y10S514/859
摘要： This invention relates to new generation triple-targeting, chiral, broad-spectrum antimicrobial 7-substituted piperidino-quinolone carboxylic acid derivatives, to their optical isomers, diastereomers or enantiomers, as well as pharmaceutically acceptable salts, hydrates, prodrugs, polymorphs and pseudopolymorphs thereof, to their preparation, to their compositions and to their use.
摘要翻译： 本发明涉及新一代三靶向，手性，广谱抗微生物7-取代的哌啶子基 - 喹诺酮羧酸衍生物，其旋光异构体，非对映异构体或对映异构体，以及其药学上可接受的盐，水合物，前药，多晶型物和假多晶型物 ，准备，组合和使用。
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3.发明申请New generation triple-targeting, chiral, broad-spectrum antimicrobial 7-substituted piperidino-quinolone carboxylic acid derivatives, their preparation, compositions and use as medicaments 失效新一代三靶向，手性，广谱抗微生物剂7-取代哌啶子基 - 喹诺酮羧酸衍生物，其制备，组合物和作为药物的用途公开(公告)号：US20080214608A1
公开(公告)日：2008-09-04
申请号：US12150075
申请日：2008-04-24
申请人： Noel John De Souza , Mahesh Vithalbhai Patel , Prasad Keshav Deshpande , Shiv Kumar Agarwal , Kandepu Sreenivas , Sheela Chandrasekharan Nair , Yati Chugh , Milind Chintaman Shukla
发明人： Noel John De Souza , Mahesh Vithalbhai Patel , Prasad Keshav Deshpande , Shiv Kumar Agarwal , Kandepu Sreenivas , Sheela Chandrasekharan Nair , Yati Chugh , Milind Chintaman Shukla
IPC分类号： A61K31/4468 , C07D211/58
CPC分类号： A61K31/47 , A61K45/06 , C07D215/233 , C07D401/04 , C07D401/14 , C07D413/12 , C07D455/04 , C07D471/04 , C07D471/08 , Y10S514/859
摘要： This invention relates to new generation triple-targeting, chiral, broad-spectrum antimicrobial 7-substituted piperidino-quinolone carboxylic acid derivatives, to their optical isomers, diastereomers or enantiomers, as well as pharmaceutically acceptable salts, hydrates, prodrugs, polymorphs and pseudopolymorphs thereof, to their preparation, to their compositions and to their use.
摘要翻译： 本发明涉及新一代三靶向，手性，广谱抗微生物7-取代的哌啶子基 - 喹诺酮羧酸衍生物，其旋光异构体，非对映异构体或对映异构体，以及其药学上可接受的盐，水合物，前药，多晶型物和假多晶型物 ，准备，组合和使用。
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4.发明授权Generation triple-targeting, chiral, broad-spectrum antimicrobial 7-substituted piperidino-quinolone carboxylic acid derivatives, their preparation, compositions and use as medicaments 失效产生三重靶向，手性，广谱抗微生物剂7-取代哌啶子基 - 喹诺酮羧酸衍生物，其制备，组合物和作为药物的用途公开(公告)号：US06964966B2
公开(公告)日：2005-11-15
申请号：US10128996
申请日：2002-04-23
申请人： Noel John De Souza , Mahesh Vithalbhai Patel , Prasad Keshav Deshpande , Shiv Kumar Agarwal , Shrikant V. Gupte , Dilip J. Upadhyay , Satish B. Bhawsar , Rupinder K. Beri , Kandepu Sreenivas , Sheela Chandrasekharan Nair , Milind Chintaman Shukla , Yati Chugh , Nitin Shetty , Ravindra D. Yeole , M. Madhav Reddy
发明人： Noel John De Souza , Mahesh Vithalbhai Patel , Prasad Keshav Deshpande , Shiv Kumar Agarwal , Shrikant V. Gupte , Dilip J. Upadhyay , Satish B. Bhawsar , Rupinder K. Beri , Kandepu Sreenivas , Sheela Chandrasekharan Nair , Milind Chintaman Shukla , Yati Chugh , Nitin Shetty , Ravindra D. Yeole , M. Madhav Reddy
IPC分类号： A61K31/095 , A61K31/191 , A61K31/47 , A61K31/4709 , A61K45/06 , A61P3/04 , A61P11/00 , A61P13/10 , A61P13/12 , A61P19/02 , A61P27/16 , A61P29/00 , A61P31/00 , A61P31/04 , C07D215/22 , C07D215/233 , C07D401/04 , C07D401/14 , C07D413/12 , C07D455/04 , C07D471/04 , C07D471/08 , C07D519/00 , A61K31/497 , C07D215/36 , C07D279/12 , C07D401/00 , C07F5/02
CPC分类号： C07D215/233 , A61K31/47 , A61K45/06 , C07D401/04 , C07D401/14 , C07D413/12 , C07D455/04 , C07D471/04 , C07D471/08
摘要： This invention relates to new generation triple-targeting, chiral, broad-spectrum antimicrobial 7-substituted piperidino-quinolone carboxylic acid derivatives, to their optical isomers, diastereomers or enantiomers, as well as pharmaceutically acceptable salts, hydrates, prodrugs, polymorphs and pseudopolymorphs thereof, to their preparation, to their compositions and to their use.
摘要翻译： 本发明涉及新一代三靶向，手性，广谱抗微生物7-取代的哌啶子基 - 喹诺酮羧酸衍生物，其旋光异构体，非对映异构体或对映异构体，以及其药学上可接受的盐，水合物，前药，多晶型物和假多晶型物 ，准备，组合和使用。
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公开(公告)号：US06878713B2
公开(公告)日：2005-04-12
申请号：US10318367
申请日：2002-12-12
申请人： Noel John De Souza , Mahesh Vithalbhai Patel , Prasad Keshav Deshpande , Shiv Kumar Agarwal , Kandepu Sreenivas , Sheela Chandrasekharan Nair , Yati Chugh , Milind Chintaman Shukla
发明人： Noel John De Souza , Mahesh Vithalbhai Patel , Prasad Keshav Deshpande , Shiv Kumar Agarwal , Kandepu Sreenivas , Sheela Chandrasekharan Nair , Yati Chugh , Milind Chintaman Shukla
IPC分类号： A61K31/47 , A61K45/06 , C07D215/22 , C07D215/233 , C07D401/04 , C07D401/14 , C07D413/12 , C07D455/04 , C07D471/04 , C07D471/08 , C07D519/00 , A61K31/497 , A61K31/44 , C07D215/16 , C07D455/06
CPC分类号： A61K31/47 , A61K45/06 , C07D215/233 , C07D401/04 , C07D401/14 , C07D413/12 , C07D455/04 , C07D471/04 , C07D471/08 , Y10S514/859
摘要： This invention relates to new generation triple-targeting, chiral, broad-spectrum antimicrobial 7-substituted piperidino-quinolone carboxylic acid derivatives, to their optical isomers, diastereomers or enantiomers, as well as pharmaceutically acceptable salts, hydrates, prodrugs, polymorphs and pseudopolymorphs thereof, to their preparation, to their compositions and to their use.
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公开(公告)号：US20050065164A1
公开(公告)日：2005-03-24
申请号：US10945504
申请日：2004-09-20
申请人： Noel De Souza , Mahesh Patel , Prasad Deshpande , Shiv Agarwal , Kandepu Sreenivas , Sheela Nair , Yati Chugh , Milind Shukla
发明人： Noel De Souza , Mahesh Patel , Prasad Deshpande , Shiv Agarwal , Kandepu Sreenivas , Sheela Nair , Yati Chugh , Milind Shukla
IPC分类号： A61K31/47 , A61K45/06 , C07D215/22 , C07D215/233 , C07D401/04 , C07D401/14 , C07D413/12 , C07D455/04 , C07D471/04 , C07D471/08 , C07D519/00 , C07D471/02 , A61K31/4709 , A61K31/4745 , A61K31/496
CPC分类号： A61K31/47 , A61K45/06 , C07D215/233 , C07D401/04 , C07D401/14 , C07D413/12 , C07D455/04 , C07D471/04 , C07D471/08 , Y10S514/859
摘要： This invention relates to new generation triple-targeting, chiral, broad-spectrum antimicrobial 7-substituted piperidino-quinolone carboxylic acid derivatives, to their optical isomers, diastereomers or enantiomers, as well as pharmaceutically acceptable salts, hydrates, prodrugs, polymorphs and pseudopolymorphs thereof, to their preparation, to their compositions and to their use.
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