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公开(公告)号：US20210059938A1
公开(公告)日：2021-03-04
申请号：US17085223
申请日：2020-10-30
Applicant: Northwestern University
Inventor： Evan A. Scott , Sijia Yi , Sean D. Allen
IPC: A61K9/127 , A61K47/34 , C08G65/334 , A61K49/00 , C08G75/14
Abstract: The present invention provides nanomaterials for the specific targeting of immune cells. Methods of treating cardiac disease and inflammatory disease are also described.
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公开(公告)号：US10821078B2
公开(公告)日：2020-11-03
申请号：US15637333
申请日：2017-06-29
Applicant: Northwestern University
Inventor： Evan A. Scott , Sijia Yi , Sean D. Allen
IPC: A61K9/127 , A61K47/34 , C08G65/334 , A61K49/00 , C08G75/14
Abstract: The present invention provides nanomaterials for the specific targeting of immune cells. Methods of treating cardiac disease and inflammatory disease are also described.
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3.发明公开公开(公告)号：US20230263729A1
公开(公告)日：2023-08-24
申请号：US18177694
申请日：2023-03-02
Applicant: Northwestern University
Inventor： Evan A. Scott , Guillermo A. Ameer , Jacqueline A. Burke , Sean D. Allen , Sijia Yi
IPC: A61K9/127 , A61K31/593 , A61K31/436 , A61K31/192 , A61P41/00 , A61K47/60 , A61K47/64 , A61K47/54 , A61P9/10
CPC classification number: A61K9/1273 , A61K31/593 , A61K31/436 , A61K31/192 , A61P41/00 , A61K47/60 , A61K47/64 , A61K47/543 , A61P9/10 , A61K9/0019
Abstract: Provided herein are nanocarriers for delivery of immunosuppressive agents. In some embodiments, provided herein are nanocarriers comprising a core comprising a poly(ethylene glycol)-block-poly(propylene sulfide) copolymer and least one therapeutic agent. In some embodiments, the nanocarriers may further comprise a targeting ligand displayed on a surface of the nanocarrier. The at least one therapeutic agent may be an anti-inflammatory agent. The disclosed nanocarriers may be incorporated into pharmaceutical compositions for use in methods of treating an inflammatory condition or preventing transplantation rejection in a subject.
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公开(公告)号：US20220002502A1
公开(公告)日：2022-01-06
申请号：US17448151
申请日：2021-09-20
Applicant: Northwestern University
Inventor： Evan A. Scott , Sean D. Allen
IPC: C08J3/14 , A61K47/34 , A61K31/436 , A61K49/00 , A61K47/36 , A61K9/127 , A61K9/107 , A61K31/352 , A61K9/00 , A61K38/46 , C12N15/113 , B01F3/08 , B01F5/02 , B01F13/00 , A61K31/365
Abstract: Described herein are flash nanoprecipitation methods capable of encapsulating hydrophobic molecules, hydrophilic molecules, bioactive protein therapeutics, or other target molecules in amphiphilic copolymer nanocarriers.
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公开(公告)号：US20210308065A1
公开(公告)日：2021-10-07
申请号：US17301512
申请日：2021-04-05
Applicant: Northwestern University
Inventor： Evan A. Scott , Sharan Bobbala , Sean D. Allen
Abstract: Provided herein are bicontinuous nanosphere nanocarrier that allow for slow, sustained release or allow for targeted release of target molecules. Further embodiments of the present invention provide bicontinuous nanosphere nanocarrier comprising a photosensitizer and a suitable polymer. Also provided are methods for making and using the photosensitive nanocarrier.
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Patent Agency Ranking
公开(公告)号：US12162997B2
公开(公告)日：2024-12-10
申请号：US17448151
申请日：2021-09-20
Applicant: Northwestern University
Inventor： Evan A. Scott , Sean D. Allen
IPC: C08J3/14 , A61K9/00 , A61K9/107 , A61K9/127 , A61K31/352 , A61K31/365 , A61K31/436 , A61K38/46 , A61K47/34 , A61K47/36 , A61K49/00 , B01F23/41 , B01F23/45 , B01F25/20 , B01F25/23 , B01F33/30 , C12N15/113
Abstract: Described herein are flash nanoprecipitation methods capable of encapsulating hydrophobic molecules, hydrophilic molecules, bioactive protein therapeutics, or other target molecules in amphiphilic copolymer nanocarriers.
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公开(公告)号：US11124612B2
公开(公告)日：2021-09-21
申请号：US16845831
申请日：2020-04-10
Applicant: Northwestern University
Inventor： Evan A. Scott , Sean D. Allen
IPC: A61K31/352 , A61K31/436 , A61K31/365 , A61K47/34 , A61K47/36 , A61K9/00 , A61K9/107 , A61K9/127 , A61K49/00 , C08J3/14 , B01F13/00 , B01F5/02 , B01F3/08 , A61K38/46 , C12N15/113
Abstract: Described herein are flash nanoprecipitation methods capable of encapsulating hydrophobic molecules, hydrophilic molecules, bioactive protein therapeutics, or other target molecules in amphiphilic copolymer nanocarriers.
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8.发明申请公开(公告)号：US20200255603A1
公开(公告)日：2020-08-13
申请号：US16845831
申请日：2020-04-10
Applicant: Northwestern University
Inventor： Evan A. Scott , Sean D. Allen
IPC: C08J3/14 , B01F13/00 , B01F5/02 , B01F3/08 , C12N15/113 , A61K38/46 , A61K49/00 , A61K9/00 , A61K31/352 , A61K9/107 , A61K9/127 , A61K47/36 , A61K31/436 , A61K47/34 , A61K31/365
Abstract: Described herein are flash nanoprecipitation methods capable of encapsulating hydrophobic molecules, hydrophilic molecules, bioactive protein therapeutics, or other target molecules in amphiphilic copolymer nanocarriers.
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公开(公告)号：US20180028446A1
公开(公告)日：2018-02-01
申请号：US15637333
申请日：2017-06-29
Applicant: Northwestern University
Inventor： Evan A. Scott , Sijia Yi , Sean D. Allen
IPC: A61K9/127 , A61K49/00 , C08G65/334 , A61K47/34
Abstract: The present invention provides nanomaterials for the specific targeting of immune cells. Methods of treating cardiac disease and inflammatory disease are also described.
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10.发明申请公开(公告)号：US20180022878A1
公开(公告)日：2018-01-25
申请号：US15656905
申请日：2017-07-21
Applicant: Northwestern University
Inventor： Evan A. Scott , Sean D. Allen
IPC: C08J3/14 , A61K31/436 , A61K49/00 , A61K47/36 , A61K9/127 , B01F13/00 , A61K31/352 , A61K9/00 , A61K38/46 , C12N15/113 , B01F3/08 , B01F5/02 , A61K47/34 , A61K9/107
CPC classification number: C08J3/14 , A61K9/0019 , A61K9/107 , A61K9/1273 , A61K31/352 , A61K31/365 , A61K31/436 , A61K38/465 , A61K47/34 , A61K47/36 , A61K49/0047 , A61K49/0054 , A61K49/0065 , B01F3/0807 , B01F3/0861 , B01F5/02 , B01F5/0256 , B01F13/0059 , C08J2371/02 , C08J2381/02 , C08J2381/04 , C12N15/113 , C12N2310/14 , C12N2320/32 , C12Y301/03001
Abstract: Described herein are flash nanoprecipitation methods capable of encapsulating hydrophobic molecules, hydrophilic molecules, bioactive protein therapeutics, or other target molecules in amphiphilic copolymer nanocarriers.
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