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公开(公告)号：US20180133711A1
公开(公告)日：2018-05-17
申请号：US15602864
申请日：2017-05-23
发明人： William E. Funk , Thomas W. McDade
CPC分类号： B01L3/5023 , A61B5/150022 , A61B5/150305 , A61B5/150358 , A61B5/150412 , A61B5/150503 , A61B5/150755 , A61B5/151 , A61B5/15105 , A61B5/15142 , B01L3/5055 , B01L2200/0689 , B01L2200/141 , B01L2200/185 , B01L2300/021 , B01L2300/0681 , B01L2300/069 , B01L2300/0816 , B01L2300/126 , G01N33/84
摘要： Disclosed are devices, kits, compositions, and methods for collecting, transporting, and detecting toxicants, pathogens, and biomarkers in a biological sample. The devices, kits, compositions and methods may be utilized to collect and transport dried blood samples from a skin prick and detect toxicants, pathogens, and biomarkers in the dried blood samples.
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公开(公告)号：US20200238275A1
公开(公告)日：2020-07-30
申请号：US16532336
申请日：2019-08-05
发明人： William E. Funk , Thomas W. McDade , Andrew Unger
摘要： Disclosed are devices, kits, compositions, and methods for collecting, transporting, and detecting toxicants, pathogens, and biomarkers in a biological sample. The devices, kits, compositions and methods may be utilized to collect and transport dried blood samples from a skin prick and detect toxicants, pathogens, and biomarkers in the dried blood samples.
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公开(公告)号：US20230074519A1
公开(公告)日：2023-03-09
申请号：US17898181
申请日：2022-08-29
发明人： Thomas W. McDade , William E. Funk
摘要： A container for collecting a sample is provided that can include a housing, an enclosure pivotally coupled to and slidably engaged with the housing, and a sample holder slidably engaged with and received within the enclosure. The sample holder can include a substrate configured to receive the sample. The container in a first configuration can include the enclosure being engaged with the housing to enclose and seal the substrate within an interior volume of the container. The container in a second configuration can include the enclosure exposing the substrate to the ambient environment.
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公开(公告)号：US11203014B2
公开(公告)日：2021-12-21
申请号：US16532336
申请日：2019-08-05
发明人： William E. Funk , Thomas W. McDade , Andrew Unger
摘要： Disclosed are devices, kits, compositions, and methods for collecting, transporting, and detecting toxicants, pathogens, and biomarkers in a biological sample. The devices, kits, compositions and methods may be utilized to collect and transport dried blood samples from a skin prick and detect toxicants, pathogens, and biomarkers in the dried blood samples.
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公开(公告)号：US20240003867A1
公开(公告)日：2024-01-04
申请号：US18469239
申请日：2023-09-18
发明人： William E. Funk , Thomas McDade
CPC分类号： G01N33/49 , A61B5/150755 , A61B5/14546 , A61B5/150022 , A61B5/150358 , G01N33/84 , A61B5/150305 , A61B5/15142 , A61B2562/0295 , A61B2562/242
摘要： The present invention provides methods, compositions, kits, and devices for detecting heavy metals in dried blood (e.g., dried blood spots). For example, the present invention provides: 1) dried blood spot paper that is detectably free of heavy metals and methods of preparing such paper using organic acid; 2) dried blood extraction solutions optimized for heavy metal detection (e.g., extraction solutions containing acetic acid and/or gold); 3) methods for estimating venous blood volume from dried blood mass; and 4) kits and kit components optimized for heavy metal detection in dried blood (e.g., kits with paper detectably free of heavy metals, heavy metal free skin wipes, metal free collection case, etc.).
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公开(公告)号：US10369564B2
公开(公告)日：2019-08-06
申请号：US15602864
申请日：2017-05-23
发明人： William E. Funk , Thomas W. McDade , Andrew Unger
摘要： Disclosed are devices, kits, compositions, and methods for collecting, transporting, and detecting toxicants, pathogens, and biomarkers in a biological sample. The devices, kits, compositions and methods may be utilized to collect and transport dried blood samples from a skin prick and detect toxicants, pathogens, and biomarkers in the dried blood samples.
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