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1.
公开(公告)号:US10550102B2
公开(公告)日:2020-02-04
申请号:US16216420
申请日:2018-12-11
Applicant: NOVARTIS AG
Inventor: Christopher M. Adams , Doug Bevan , Michael Paul Capparelli , Takeru Ehara , Luciana Ferrara , Nan Ji , Erik Meredith , Muneto Mogi , James J. Powers , Ganesh Prasanna , Nello Mainolfi , Mitsunori Kato
IPC: C07D401/14 , C07D413/14 , C07D401/10 , C07D401/12 , A61K9/00 , A61K31/4439 , A61K31/454 , A61K31/4545 , A61K31/4725 , C07D405/14 , C07D401/04
Abstract: The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof; a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.
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公开(公告)号:US12129246B1
公开(公告)日:2024-10-29
申请号:US18589841
申请日:2024-02-28
Applicant: Novartis AG
Inventor: Daniela Angst , Philippe Bolduc , Matthew William Carson , Atwood Kim Cheung , Véronique Darsigny , Xiang Gao , Viktor Hornak , Keith Jendza , Rajesh Karki , Ajay Kumar Lal , Gang Liu , Justin Yik Ching Mao , Jeffrey M. McKenna , Erik Meredith , Muneto Mogi , Vivek Rauniyar , Liansheng Su , Ritesh Tichkule , Shuangxi Wang , Chun Zhang , Liang Zhao , Rui Zheng
IPC: C07D403/14 , A61K31/517 , A61K31/55 , A61K45/06 , C07D239/95 , C07D401/12 , C07D401/14
CPC classification number: C07D403/14 , A61K31/517 , A61K31/55 , A61K45/06 , C07D239/95 , C07D401/12 , C07D401/14
Abstract: The disclosure relates to a compound of Formula (I):
or a pharmaceutically acceptable salt thereof wherein A, Ra to Rd, and R4 to R7, are as described herein, as well as compositions and methods of using such compounds.
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