公开(公告)号：US20160274345A1

公开(公告)日：2016-09-22

申请号：US15060585

申请日：2016-03-03

Applicant: OLYMPUS CORPORATION

Inventor： Makio UENO ,  Masahito DOHI ,  Atsuhiro TSUCHIYA ,  Hiroyasu HEBIISHI

IPC: G02B21/00 ,  G01N21/64 ,  G02B27/00 ,  G02B21/36 ,  G02B27/14

CPC classification number: G02B21/0076 ,  A61B5/0059 ,  A61B5/0062 ,  G01N21/6402 ,  G01N21/6458 ,  G01N21/6486 ,  G02B21/0032 ,  G02B21/0084 ,  G02B21/361 ,  G02B27/0025 ,  G02B27/141

Abstract: A fluorescence observation unit includes a scanner that scans ultrashort pulsed laser light, a pupil projection lens that focuses the scanned ultrashort pulsed laser light, an image-forming lens that converts the focused ultrashort pulsed laser light to substantially collimated light and causes the ultrashort pulsed laser light to be incident on the objective lens, and a dichroic mirror that splits off, from the optic path of the ultrashort pulsed laser light, fluorescence generated in a sample due to irradiation with the ultrashort pulsed laser light and collected by the objective lens. The image-forming lens includes a first optical system having positive refractive power, and a second optical system having negative refractive power and disposed at a position closer to the scanner than the first optical system is. The dichroic mirror is disposed between the first optical system and the second optical system.

Abstract translation: 荧光观察单元包括扫描超短脉冲激光的扫描器，聚焦扫描的超短脉冲激光的瞳孔投影透镜，将聚焦的超短脉冲激光转换成基本准直的光并使超短脉冲激光 入射在物镜上的光和从超短脉冲激光的光路分离的二向色镜，由于用超短脉冲激光照射并由物镜收集而在样品中产生的荧光。 图像形成透镜包括具有正屈光力的第一光学系统和具有负屈光力的第二光学系统，并且设置在比第一光学系统更靠近扫描仪的位置处。 分色镜设置在第一光学系统和第二光学系统之间。

公开(公告)号：US20150212310A1

公开(公告)日：2015-07-30

申请号：US14608979

申请日：2015-01-29

Applicant: OLYMPUS CORPORATION

Inventor： Tatsushi FUKUDA ,  Hiroyasu HEBIISHI

IPC: G02B21/33

CPC classification number: G02B21/33

Abstract: It is an object of the present invention to provide a microscope that is capable of precisely controlling the amount of an immersion medium held in a gap between an objective lens and a mounting part, and that is capable of observing a specimen without varying the mounting part. The microscope includes a supply port from which an immersion medium is supplied to a gap between a film-like mounting part on which a specimen is loaded and an immersion objective lens, and a suction port that is arranged so as to be able to be brought into contact with an immersion medium supplied from the supply port, and from which the immersion medium can be sucked.

Abstract translation: 本发明的目的是提供一种能够精确地控制保持在物镜和安装部之间的间隙中的浸渍介质的量的显微镜，并且能够观察样本而不改变安装部分 。 显微镜包括供给口，浸没介质从供给口供给到载置有试样的薄膜状安装部和浸没物镜之间的间隙，以及能够被配置的吸入口 与从供给口供给的浸渍介质接触，从该浸渍介质吸入浸渍介质。

公开(公告)号：US20160004061A1

公开(公告)日：2016-01-07

申请号：US14789293

申请日：2015-07-01

Applicant: OLYMPUS CORPORATION

Inventor： Hiroyasu HEBIISHI ,  Masaru MIZUNAKA ,  Shintaro KOBAYASHI ,  Akihiro KITAHARA

IPC: G02B21/06

CPC classification number: G02B21/0088 ,  G02B21/242 ,  G02B21/248

Abstract: A microscope includes: an objective lens having an optical system; a correction collar provided on the objective lens and configured to move the optical system in a direction of an optical axis of the optical system by rotating around the objective lens to correct aberration; a switching unit to which the objective lens is attachable and which switches a position of the objective lens; a supporting unit for supporting the switching unit; and a focusing unit that holds the supporting unit such that the supporting unit is movable along the optical axis of the objective lens. A correction collar operating device is detachably attached to the supporting unit and includes: an input unit for inputting rotary force to rotate the correction collar; and a correction collar driving unit for rotating the correction collar according to the rotary force while the correction collar driving unit has contact with the correction collar.

Abstract translation: 显微镜包括：具有光学系统的物镜; 设置在所述物镜上并且被配置为通过绕所述物镜旋转以校正像差而沿所述光学系统的光轴的方向移动所述光学系统的校正套环; 物镜可连接的开关单元，并且切换物镜的位置; 支撑单元，用于支撑切换单元; 以及聚焦单元，其保持所述支撑单元，使得所述支撑单元可沿着所述物镜的光轴移动。 校正环操作装置可拆卸地附接到支撑单元，并且包括：用于输入旋转力以旋转校正套环的输入单元; 以及校正轴环驱动单元，用于在校正轴环驱动单元与校正轴环接触的同时根据旋转力旋转校正轴环。

公开(公告)号：US20180149849A1

公开(公告)日：2018-05-31

申请号：US15878603

申请日：2018-01-24

Applicant: OLYMPUS CORPORATION

Inventor： Makio UENO ,  Masahito DOHI ,  Atsuhiro TSUCHIYA ,  Hiroyasu HEBIISHI

IPC: G02B21/00 ,  A61B5/00 ,  G01N21/64 ,  G02B27/00 ,  G02B27/14 ,  G02B21/36

CPC classification number: G02B21/0076 ,  A61B5/0059 ,  A61B5/0062 ,  G01N21/6402 ,  G01N21/6458 ,  G01N21/6486 ,  G02B21/0032 ,  G02B21/0084 ,  G02B21/361 ,  G02B27/0025 ,  G02B27/141

Abstract: A fluorescence observation apparatus includes a fluorescence observation unit, which includes a scanner that scans ultrashort pulsed laser light from a light source, a pupil projection lens that focuses the laser light scanned by the scanner, an image-forming lens that converts the focused laser light to substantially collimated light and causes the laser light to be incident on an objective lens, and a dichroic mirror that splits off fluorescence that is generated by the laser light focused on a sample by the objective lens and is collected by the objective lens. A photodetector detects the fluorescence split off by the dichroic mirror. A multi-mode optical fiber connects the fluorescence observation unit and the photodetector. A swiveling mechanism causes the fluorescence observation unit to swivel about an axis near the focal position of the objective lens. And a light-source optical fiber connects the light source and the fluorescence observation unit.

公开(公告)号：US20150260974A1

公开(公告)日：2015-09-17

申请号：US14639614

申请日：2015-03-05

Applicant: OLYMPUS CORPORATION

Inventor： Tatsushi FUKUDA ,  Hiroyasu HEBIISHI

IPC: G02B21/26

CPC classification number: G02B21/26 ,  C12M41/14 ,  C12M41/36

Abstract: Provided is a culture microscope including a culturing space that is provided with a stage on which a specimen is mounted; an adjacent space that is adjacent to the culturing space and in which a driving mechanism of the stage is disposed; a stationary partition that divides the adjacent space and the culturing space and that is also provided with a first through-hole; a tabular movable partition that is disposed at a position where the movable partition closes the first through-hole, that has a second through-hole that is smaller than the first through-hole, that is supported so as to be movable parallel to the stationary partition, and that is larger than the first through-hole; and a lid member that is disposed at a position where the lid member closes the second through-hole of the movable partition and that is supported so as to be movable parallel to the movable partition.

Abstract translation: 本发明提供一种培养显微镜，其特征在于，包括：培养空间，设置有载置有试样的台; 与所述培养空间相邻并且设置所述台架的驱动机构的相邻空间; 分隔相邻空间和培养空间并且还设置有第一通孔的固定分隔件; 该活动隔板设置在可移动隔板封闭第一通孔的位置，该第一通孔具有比第一通孔小的第二通孔，该第二通孔被平行于静止件 分隔，大于第一通孔; 以及盖构件，其设置在所述盖构件闭合所述可动隔板的第二通孔的位置，并且被支撑为能够平行于所述可动隔板移动的位置。