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Patent Agency Ranking
公开(公告)号：US20160274345A1
公开(公告)日：2016-09-22
申请号：US15060585
申请日：2016-03-03
Applicant: OLYMPUS CORPORATION
Inventor： Makio UENO , Masahito DOHI , Atsuhiro TSUCHIYA , Hiroyasu HEBIISHI
CPC classification number: G02B21/0076 , A61B5/0059 , A61B5/0062 , G01N21/6402 , G01N21/6458 , G01N21/6486 , G02B21/0032 , G02B21/0084 , G02B21/361 , G02B27/0025 , G02B27/141
Abstract: A fluorescence observation unit includes a scanner that scans ultrashort pulsed laser light, a pupil projection lens that focuses the scanned ultrashort pulsed laser light, an image-forming lens that converts the focused ultrashort pulsed laser light to substantially collimated light and causes the ultrashort pulsed laser light to be incident on the objective lens, and a dichroic mirror that splits off, from the optic path of the ultrashort pulsed laser light, fluorescence generated in a sample due to irradiation with the ultrashort pulsed laser light and collected by the objective lens. The image-forming lens includes a first optical system having positive refractive power, and a second optical system having negative refractive power and disposed at a position closer to the scanner than the first optical system is. The dichroic mirror is disposed between the first optical system and the second optical system.
Abstract translation: 荧光观察单元包括扫描超短脉冲激光的扫描器，聚焦扫描的超短脉冲激光的瞳孔投影透镜，将聚焦的超短脉冲激光转换成基本准直的光并使超短脉冲激光 入射在物镜上的光和从超短脉冲激光的光路分离的二向色镜，由于用超短脉冲激光照射并由物镜收集而在样品中产生的荧光。 图像形成透镜包括具有正屈光力的第一光学系统和具有负屈光力的第二光学系统，并且设置在比第一光学系统更靠近扫描仪的位置处。 分色镜设置在第一光学系统和第二光学系统之间。
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公开(公告)号：US20160313545A1
公开(公告)日：2016-10-27
申请号：US15098092
申请日：2016-04-13
Applicant: OLYMPUS CORPORATION
Inventor： Kanako KONDO , Makio UENO
CPC classification number: G02B21/0048 , G02B21/0032 , G02B21/0076 , G02B21/08 , G02B26/101 , G02B26/105
Abstract: In order to allow precise observation of a specimen at an observation point with a desired depth without changing the working distance of an objective optical system while employing a simple configuration, a laser scanning microscope according to the present invention includes an objective lens having a plurality of optical elements that are disposed with gaps therebetween in an optical-axis direction and that condense laser light emitted from a light source onto a specimen and also having an adjustment ring that allows changing of the focal point by moving the optical elements in the optical-axis direction; a scanner that has a galvanometer mirror capable of oscillating about a predetermined oscillation axis and that scans the laser light condensed onto the specimen by the objective lens in accordance with an oscillation angle of the galvanometer mirror; a light detecting unit that obtains image information of the specimen on the basis of return light returned from the specimen scanned with the laser light; and a scanner controlling unit that controls the oscillation angle of the galvanometer mirror so as to maintain an observation range of the specimen observed by the light detecting unit on the basis of the positions of the optical elements moved by the adjustment ring.
Abstract translation: 本发明的激光扫描显微镜为了能够在不改变物镜光学系统的工作距离的同时以期望深度的观察点精确观察样本，包括具有多个 光学元件，其在光轴方向上设置有间隙，并且将从光源发射的激光聚焦到样本上，并且还具有允许通过在光轴中移动光学元件来改变焦点的调节环 方向; 扫描仪，其具有能够围绕预定的摆动轴摆动的电流计反射镜，并且根据所述电流计反射镜的振荡角度来扫描由所述物镜聚集在所述样本上的激光; 光检测单元，其基于从用激光扫描的样本返回的返回光获取样本的图像信息; 以及扫描器控制单元，其基于由调节环移动的光学元件的位置来控制检流计镜的振荡角度，以保持由光检测单元观察到的样本的观察范围。
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公开(公告)号：US20140376078A1
公开(公告)日：2014-12-25
申请号：US14298707
申请日：2014-06-06
Applicant: OLYMPUS CORPORATION
Inventor： Yoshihiro SHIMADA , Makio UENO , Shingo TAMANO , Naoki HAYASHI , Eiji YOKOI
CPC classification number: G02B21/0032 , G02B21/002 , G02B21/0036 , G02B21/0096 , G02B21/06 , G02B21/26 , G02B27/4261
Abstract: A scanning optical microscope includes a light source, a light converging optical system, a stage, a scanning unit which displaces an illumination light and the stage relatively, a detecting optical system, and a photodetector. A light modulation element and a relay optical system are disposed on the light converging optical system side of the light source, and a modulated signal having only amplitude changed is input to the light modulation element, and the light modulation element is positioned such that the illumination light emerged from the light modulation element with respect to the modulated signal of a predetermined amplitude coincides with an optical axis of the light converging optical system, and a position of a pupil of the light converging optical system and a position of the light modulation element are conjugate through at least the relay optical system.
Abstract translation: 扫描光学显微镜包括光源，聚光光学系统，舞台，相对地移动照明光和舞台的扫描单元，检测光学系统和光电检测器。 光调制元件和中继光学系统设置在光源的聚光光学系统侧，并且只有振幅改变的调制信号被输入到光调制元件，并且光调制元件被定位成使得照明 相对于预定幅度的调制信号从光调制元件出射的光与会聚光学系统的光轴重合，会聚光学系统的光瞳位置和光调制元件的位置是 通过至少中继光学系统共轭。
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公开(公告)号：US20180149849A1
公开(公告)日：2018-05-31
申请号：US15878603
申请日：2018-01-24
Applicant: OLYMPUS CORPORATION
Inventor： Makio UENO , Masahito DOHI , Atsuhiro TSUCHIYA , Hiroyasu HEBIISHI
CPC classification number: G02B21/0076 , A61B5/0059 , A61B5/0062 , G01N21/6402 , G01N21/6458 , G01N21/6486 , G02B21/0032 , G02B21/0084 , G02B21/361 , G02B27/0025 , G02B27/141
Abstract: A fluorescence observation apparatus includes a fluorescence observation unit, which includes a scanner that scans ultrashort pulsed laser light from a light source, a pupil projection lens that focuses the laser light scanned by the scanner, an image-forming lens that converts the focused laser light to substantially collimated light and causes the laser light to be incident on an objective lens, and a dichroic mirror that splits off fluorescence that is generated by the laser light focused on a sample by the objective lens and is collected by the objective lens. A photodetector detects the fluorescence split off by the dichroic mirror. A multi-mode optical fiber connects the fluorescence observation unit and the photodetector. A swiveling mechanism causes the fluorescence observation unit to swivel about an axis near the focal position of the objective lens. And a light-source optical fiber connects the light source and the fluorescence observation unit.
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公开(公告)号：US20160103309A1
公开(公告)日：2016-04-14
申请号：US14874009
申请日：2015-10-02
Applicant: OLYMPUS CORPORATION
Inventor： Shingo SUZUKI , Takuma KIMURA , Makio UENO
CPC classification number: G02B21/06 , G02B21/24 , G02B26/0816 , G02B27/144 , G02B27/145
Abstract: A microscope system according to the present invention includes a laser light source, a plurality of laser microscopes, and an optical path switching unit that is provided between the laser light source and the laser microscopes and switches a supply destination of a laser beam among the plurality of laser microscopes by changing a beam splitter to be arranged on an incident optical axis, in which each of the laser microscopes includes an optical axis adjustment unit that adjusts an optical axis of the laser beam, and a control unit that controls the optical axis adjustment unit based on identification information about the beam splitter arranged on the incident optical axis.
Abstract translation: 根据本发明的显微镜系统包括激光源，多个激光显微镜和光路切换单元，其设置在激光光源和激光显微镜之间并切换多个激光束的激光束的供给目的地 通过改变配置在入射光轴上的分束器，其中每个激光显微镜包括调整激光束的光轴的光轴调节单元和控制光轴调节的控制单元 基于关于在入射光轴上布置的分束器的识别信息的单元。
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