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公开(公告)号：US20240415428A1
公开(公告)日：2024-12-19
申请号：US18817446
申请日：2024-08-28
Applicant: OLYMPUS CORPORATION
Inventor： Koki MORISHITA , Hiromi TAKAHASHI
IPC: A61B5/1455
Abstract: An image processing apparatus includes a processor having hardware. The processor acquires a first image, a second image, and a third image of living tissue irradiated with first light, second light, and third light, respectively, calculates an index value that is correlated with a blood volume in the living tissue based on signal values of the first image and the second image, and calculates oxygen saturation of the living tissue based on the index value and a signal value of the third image. Each of the first light and the second light has a wavelength at which an absorption coefficient of oxygenated hemoglobin and an absorption coefficient of deoxygenated hemoglobin are the same, and the third light has a wavelength at which the absorption coefficients of the oxygenated hemoglobin and the absorption coefficient of the deoxygenated hemoglobin are different from each other.
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公开(公告)号：US20140092282A1
公开(公告)日：2014-04-03
申请号：US14084713
申请日：2013-11-20
Applicant: OLYMPUS CORPORATION
Inventor： Koki MORISHITA
CPC classification number: G01J3/0205 , G01J3/26 , G01J3/32 , G01J3/36 , H04N9/097
Abstract: A spectral imaging apparatus includes a variable wavelength spectroscopic element changing a distance between surfaces of a pair of optical substrates opposite to each other to change a peak wavelength, a light splitting unit which splits light transmitted by the variable wavelength spectroscopic element into components in each of the predetermined wavelength ranges, and image-capturing units each of which captures only a spectral image formed by the components in each of the wavelength ranges into which the transmitted light is split by the light splitting unit, the wavelength ranges including the peak wavelengths respectively.
Abstract translation: 光谱成像装置包括：可变波长分光元件，改变彼此相对的一对光学基板的表面之间的距离以改变峰值波长;分光单元，其将由可变波长分光元件透射的光分成各自的分量; 所述预定波长范围和每个拍摄单元仅捕获由分光单元分离透射光的波长范围中的分量形成的分光图像，分别包括峰值波长的波长范围。
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公开(公告)号：US20240188794A1
公开(公告)日：2024-06-13
申请号：US18585612
申请日：2024-02-23
Applicant: OLYMPUS CORPORATION
Inventor： Hiromi TAKAHASHI , Koki MORISHITA
CPC classification number: A61B1/000094 , A61B1/00048 , A61B1/0638 , G06T7/00 , G06T2207/10068
Abstract: A biological-image generating method includes: acquiring first and second images of biological tissue respectively irradiated with first and second illumination light; and generating a biological image from the first and second images. The first illumination light has a wavelength which is selected from a range between 500 nm and 600 nm and at which reflectance thereof is not dependent on an oxygen saturation. The second illumination light has a wavelength which is selected from a range between 600 nm and 800 nm and at which reflectance thereof is dependent on the oxygen saturation. The generating includes: calculating an indicator value expressing the oxygen saturation from a first pixel value of each pixel in the first image and a second pixel value of each pixel in the second image; and allocating a display mode corresponding to the indicator value to each pixel of the biological image.
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Patent Agency Ranking
公开(公告)号：US20180000334A1
公开(公告)日：2018-01-04
申请号：US15704415
申请日：2017-09-14
Applicant: OLYMPUS CORPORATION
Inventor： Koki MORISHITA
CPC classification number: A61B1/0638 , A61B1/00006 , A61B1/00009 , A61B1/00045 , A61B1/04 , A61B1/045 , A61B1/0646 , A61B1/0684
Abstract: Provided is a biological observation apparatus including: illuminating portions that irradiate biological tissue with illumination light including light in R, G, and B regions, respectively; an image acquisition portion that acquires image signals from reflected light of the illumination light coming from the biological tissue; narrow-band-light generating portions that are disposed in the illuminating portions or the image acquisition portion and that, in wavelength bands of the illumination light, generate two narrow-band beams for at least one of the R, G, and B wavelength bands constituting the illumination light, on either side of a central wavelength of that wavelength band; and an image-generating portion that generates an image on the basis of two or more types of the image signals obtained from the reflected light including two or more narrow bands acquired by the image acquisition portion.
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公开(公告)号：US20140316279A1
公开(公告)日：2014-10-23
申请号：US14321978
申请日：2014-07-02
Applicant: OLYMPUS CORPORATION
Inventor： Koki MORISHITA
IPC: A61B5/00
CPC classification number: A61B5/4887 , A61B1/00009 , A61B1/0005 , A61B1/0638 , A61B5/0062 , A61B5/742
Abstract: Provided is a biological observation apparatus including irradiating portions that radiate illumination light onto biological tissue, an imaging portion that, of reflected light reflected at the biological tissue due to the illumination light radiated by the irradiating portions, captures reflected light in a wavelength band in which an absorption characteristic of β-carotene is greater than an absorption characteristic of hemoglobin, thus acquiring a reflected-light image, and a display portion that displays the reflected-light image acquired by the imaging portion.
Abstract translation: 本发明提供一种生物观察装置，其包括将照射光照射到生物体组织上的照射部，由于照射部照射的照明光而在生物体组织反射的反射光捕获其波长带的反射光的成像部， 胡萝卜素的吸收特性大于血红蛋白的吸收特性，从而获得反射光图像，显示部分显示由成像部分获取的反射光图像。
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公开(公告)号：US20220287554A1
公开(公告)日：2022-09-15
申请号：US17831649
申请日：2022-06-03
Applicant: OLYMPUS CORPORATION
Inventor： Takeshi ITO , Masayoshi SAITO , Koki MORISHITA
Abstract: A light source device includes a first light source, a second light source, and a processor. The processor controls, based on spectrum setting information, an emitted light amount of the first light source and an emitted light amount of the second light source so that the emitted light amount of the first light source becomes larger than the emitted light amount of the second light source. The observation object includes a region of interest, a merkmal, and a peripheral portion. The spectrum setting information is set based on a merkmal observed ratio that is a ratio between a spectral reflectance in the merkmal and a spectral reflectance in the peripheral portion. A degree of disassociation of the merkmal observed ratio in the first wavelength region from 1 is greater than a degree of disassociation of the merkmal observed ratio in the second wavelength region from 1.
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公开(公告)号：US20160302652A1
公开(公告)日：2016-10-20
申请号：US15198407
申请日：2016-06-30
Applicant: OLYMPUS CORPORATION
Inventor： Koki MORISHITA
CPC classification number: A61B1/043 , A61B1/00006 , A61B1/0638 , A61B1/07 , G01N21/474 , G01N21/6456 , G01N2021/4742 , G01N2201/061 , G01N2201/0612 , G01N2201/08 , G02B23/243 , G02B23/2469 , G02B2207/113 , H04N5/2256 , H04N2005/2255
Abstract: A fluorescence observation apparatus including: a light source unit that simultaneously irradiates a subject with illumination light and excitation light having a partial wavelength band of the wavelength band of the illumination light; an objective lens unit that forms an image of reflected light reflected at the subject due to being irradiated with the illumination light and an image of fluorescence generated at the subject due to being irradiated with the excitation light; a single image capturing element that simultaneously acquires the images of reflected light and fluorescence; a filter that is disposed between the objective lens unit and the image capturing and that transmits the light, except the excitation light, to the image capturing element; and a light-adjusting unit that adjusts the output intensity of the illumination light and the output intensity of the excitation light from the light source unit independently of each other.
Abstract translation: 一种荧光观察装置，包括：光源单元，其用照明光和具有所述照明光的波长带的部分波段的激发光同时照射被检体; 物镜单元，其通过照射照射光而形成在被检体上反射的反射光的图像和由于照射激发光而在被检体处产生的荧光的图像; 同时获取反射光和荧光的图像的单个图像捕获元件; 滤光器，设置在所述物镜单元与所述图像拍摄之间，并将所述激发光以外的光透射到所述图像拍摄元件; 以及调节单元，其彼此独立地调节照明光的输出强度和来自光源单元的激发光的输出强度。
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公开(公告)号：US20150342447A1
公开(公告)日：2015-12-03
申请号：US14823381
申请日：2015-08-11
Applicant: OLYMPUS CORPORATION
Inventor： Koki MORISHITA
CPC classification number: A61B1/00009 , A61B1/00186 , A61B1/043 , A61B1/0638 , A61B1/0646
Abstract: A fluoroscopy apparatus includes a light-source configured to irradiate biological tissue with illumination light including excitation light; and a processor including hardware, wherein the processor is configured to implement: a reflected-light-image generating portion configured to generate a reflected-light-image of the biological tissue based on captured reflected light reflected from the biological tissue irradiated with the illumination light from the light-source; and a fluorescence-image generating portion configured to generate a fluorescence image based on captured fluorescence generated at the biological tissue due to irradiation thereof with the excitation light from the light-source, wherein the illumination light is visible light that does not include at least a portion of the wavelength region between 490 nm and 540 nm, and wherein the excitation light includes some wavelengths of the illumination light and generates fluorescence having a wavelength included in the at least a portion of the wavelength region.
Abstract translation: 荧光透视装置包括被配置为用生物组织照射包括激发光的照明光的光源; 以及包括硬件的处理器，其中所述处理器被配置为实现：反射光图像生成部分，被配置为基于从所述照射光照射的生物组织反射的所捕获的反射光产生所述生物组织的反射光图像 从光源; 以及荧光图像生成部，其被配置为基于由于来自所述光源的激发光的照射而在所述生物体组织处产生的捕捉到的荧光而产生荧光图像，其中，所述照明光是不包括至少一个 波长区域的部分在490nm和540nm之间，并且其中激发光包括照明光的一些波长并且产生具有包括在波长区域的至少一部分中的波长的荧光。
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