公开(公告)号：US20080249384A1

公开(公告)日：2008-10-09

申请号：US11661867

申请日：2005-09-05

申请人： Ole Skyggebjerg ,  Kristian Glejbol

发明人： Ole Skyggebjerg ,  Kristian Glejbol

IPC分类号： A61B5/055

CPC分类号： A61B5/1473 ,  A61B5/0031 ,  A61B5/14532 ,  A61B5/7445

摘要： This application relates to glucose monitoring systems for continuously measuring the glucose concentration in a patients blood. The system is adapted to communicate with one or more sensors (10, 20) for transcutaneous insertion into a patient and for producing sensor signals related to the glucose concentration. The system comprises an electronic calculator unit and a display (14) for displaying the measured glucose concentration. The electronic calculator unit further comprises means for calculating an estimate of the uncertainty, i.e. the degree of accuracy of the glucose measurement, and the display is configured for displaying an interval representing said uncertainty (15).

摘要翻译： 本申请涉及用于连续测量患者血液中葡萄糖浓度的葡萄糖监测系统。 该系统适于与一个或多个传感器（10,20）进行通信，用于经皮插入患者体内并产生与葡萄糖浓度相关的传感器信号。 该系统包括电子计算器单元和用于显示所测量的葡萄糖浓度的显示器（14）。 电子计算器单元还包括用于计算不确定度的估计的装置，即葡萄糖测量的准确度，并且显示被配置为显示表示所述不确定性的间隔（15）。

公开(公告)号：US20100145262A1

公开(公告)日：2010-06-10

申请号：US12598283

申请日：2008-04-07

申请人： Henrik Bengtsson ,  Leif Engmann Kristensen ,  Joergen Smedegaard ,  Morten Simoni Spjuth ,  Ole Skyggebjerg

发明人： Henrik Bengtsson ,  Leif Engmann Kristensen ,  Joergen Smedegaard ,  Morten Simoni Spjuth ,  Ole Skyggebjerg

IPC分类号： A61M5/168 ,  G05B19/00

CPC分类号： A61B5/4839 ,  A61B5/14532 ,  A61B5/7275 ,  A61M5/1723 ,  A61M2005/14208 ,  G06F19/3456 ,  G16H10/60 ,  G16H50/50

摘要： A closed loop control system for a medical drug delivery device logs historical data such as drug delivered and corresponding physiological parameters such as blood glucose level. On the basis of the logged historical data, the system calculates an estimated event forecast on which basis the system further calculates the necessary, prudent future drug delivery profile in order to counter delay in the closed loop. The estimated event forecast is presented to the user, the user is thereby given the possibility to accept, reject or adjust the event forecast and the corresponding drug delivery profile. Dynamic and adaptive safety limits to the drug delivery and the physiological parameter can be set by the user and will dynamically follow the drug delivery profile and the event forecast and will further optimize based on the learned behavioural pattern of the user. The user can set the safety level as a percentage of deviation to the drug delivery profile.

摘要翻译： 用于医疗药物递送装置的闭环控制系统记录诸如药物递送的历史数据和相应的生理参数，例如血糖水平。 在记录的历史数据的基础上，系统计算一个估计的事件预测，在哪个基础上，系统进一步计算必要的审慎的未来药物传递概况，以便对闭环中的延迟进行计数。 向用户呈现估计的事件预测，从而给予用户接受，拒绝或调整事件预测和相应的药物递送简档的可能性。 药物输送的动态和适应性安全限制和生理参数可由用户设定，并将动态地遵循药物递送情况和事件预测，并将根据学习的用户行为模式进一步优化。 用户可以将安全等级设置为与药物输送配置文件的偏差百分比。

公开(公告)号：US07397730B2

公开(公告)日：2008-07-08

申请号：US11544525

申请日：2006-10-05

申请人： Ole Skyggebjerg ,  Lars Hofmann Christensen ,  Rasmus Panduro ,  Nina Bjorlig ,  Steffen Lav ,  Barry Weben ,  Manuel Alvarez Icaza ,  Steven Syme

发明人： Ole Skyggebjerg ,  Lars Hofmann Christensen ,  Rasmus Panduro ,  Nina Bjorlig ,  Steffen Lav ,  Barry Weben ,  Manuel Alvarez Icaza ,  Steven Syme

IPC分类号： G04B47/00 ,  A61M5/00 ,  A61M5/32

CPC分类号： A61M5/20 ,  A61J7/0436 ,  A61M5/178 ,  A61M5/28 ,  A61M5/3129 ,  A61M2005/3125 ,  A61M2205/50 ,  A61M2205/581 ,  G04B25/06 ,  G04F1/005

摘要： The invention relates to a timer device capable of performing one or more control actions in response to the time lapsed since a user initiated action took place. The timer device comprises contact means operatable between two conditions, timer means, and means for storing first and second time stamps. The device further comprises control means for setting a first time stamp in response to the contact means being operated between first and second conditions, setting a second time stamp in response to the contact means being operated between the second and first conditions, calculating the time elapsed between the two time stamps, comparing the elapsed time with a preset time value, and performing a control action if the elapsed time is greater than the preset time value.

摘要翻译： 本发明涉及一种定时器装置，其能够响应于由于用户发起动作而发生的时间而执行一个或多个控制动作。 定时器装置包括可在两个状态之间操作的接触装置，定时器装置和用于存储第一和第二时间戳的装置。 该装置还包括控制装置，用于响应于在第一和第二条件之间操作的接触装置来设置第一时间戳，响应于在第二和第一条件之间操作的接触装置设置第二时间戳，计算经过的时间 在两个时间戳之间，将经过的时间与预设时间值进行比较，以及如果经过时间大于预设时间值，则执行控制动作。

公开(公告)号：US20070030764A1

公开(公告)日：2007-02-08

申请号：US11544525

申请日：2006-10-05

申请人： Ole Skyggebjerg ,  Lars Christensen ,  Rasmus Panduro ,  Nina Bjorlig ,  Steffen Lav ,  Barry Weben ,  Manuel Alvarez-Icaza ,  Steven Syme

发明人： Ole Skyggebjerg ,  Lars Christensen ,  Rasmus Panduro ,  Nina Bjorlig ,  Steffen Lav ,  Barry Weben ,  Manuel Alvarez-Icaza ,  Steven Syme

IPC分类号： G04F10/00

CPC分类号： A61M5/20 ,  A61J7/0436 ,  A61M5/178 ,  A61M5/28 ,  A61M5/3129 ,  A61M2005/3125 ,  A61M2205/50 ,  A61M2205/581 ,  G04B25/06 ,  G04F1/005

摘要： The invention relates to a timer device capable of performing one or more control actions in response to the time lapsed since a user initiated action took place. The timer device comprises contact means operatable between two conditions, timer means, and means for storing first and second time stamps. The device further comprises control means for setting a first time stamp in response to the contact means being operated between first and second conditions, setting a second time stamp in response to the contact means being operated between the second and first conditions, calculating the time elapsed between the two time stamps, comparing the elapsed time with a preset time value, and performing a control action if the elapsed time is greater than the preset time value.

摘要翻译： 本发明涉及一种定时器装置，其能够响应于由于用户发起动作而发生的时间而执行一个或多个控制动作。 定时器装置包括可在两个状态之间操作的接触装置，定时器装置和用于存储第一和第二时间戳的装置。 该装置还包括控制装置，用于响应于在第一和第二条件之间操作的接触装置来设置第一时间戳，响应于在第二和第一条件之间操作的接触装置设置第二时间戳，计算经过的时间 在两个时间戳之间，将经过的时间与预设时间值进行比较，以及如果经过时间大于预设时间值，则执行控制动作。

公开(公告)号：US20080312859A1

公开(公告)日：2008-12-18

申请号：US11661866

申请日：2005-09-05

申请人： Ole Skyggebjerg ,  Arne Stjernholm Madsen ,  Michael Gerstenberg

发明人： Ole Skyggebjerg ,  Arne Stjernholm Madsen ,  Michael Gerstenberg

IPC分类号： G06F19/00 ,  G01N33/48

CPC分类号： A61B5/1495 ,  A61B5/14532 ,  A61B2562/0295

摘要： This invention relates to procedures for the calibration of systems for continuously measuring the concentration of substances in a body fluid. The system comprises first and second sensors adapted for subcutaneous insertion and an electronic calculator unit adapted for measuring signals from the two sensors. The system is calibrated following the steps of: a) introducing the first sensor subcutaneously, b) calibrating the first sensor, c) obtaining sensor data S1(t) provided by the first sensor, d) introducing the second sensor subcutaneously, e) obtaining sensor data S2(t) provided by the second sensor, f) determining the rate of change over time δR(t)/δt, R(t) being a signal which correlates to sensor data S2(t) over time, and g) performing a calibration of the second sensor when δR(t)/δt is less than a predetermined value, said calibration of the second sensor being performed using sensor data S1(t) obtained by the first sensor.

摘要翻译： 本发明涉及用于校准连续测量体液中物质浓度的系统的方法。 该系统包括适于皮下插入的第一和第二传感器以及适于测量来自两个传感器的信号的电子计算器单元。 按照以下步骤校准系统：a）皮下引入第一传感器，b）校准第一传感器，c）获得由第一传感器提供的传感器数据S1（t），d）皮下引入第二传感器，e）获得 由第二传感器提供的传感器数据S2（t），f）确定随时间的变化率ΔR（t）/ deltat，R（t）是与传感器数据S2（t）随时间相关联的信号，g） 当deltaR（t）/ deltat小于预定值时，执行第二传感器的校准，使用由第一传感器获得的传感器数据S1（t）来执行第二传感器的校准。

公开(公告)号：US20080208627A1

公开(公告)日：2008-08-28

申请号：US11908522

申请日：2006-03-14

申请人： Ole Skyggebjerg

发明人： Ole Skyggebjerg

IPC分类号： G06Q50/00

CPC分类号： A61M5/14248 ,  A61M5/1413 ,  A61M2005/14208 ,  A61M2205/3569 ,  A61M2205/3592 ,  G06Q50/22 ,  H04L63/10 ,  H04L63/108 ,  H04W12/003

摘要： The present invention relates to secure paring of electronically controlled devices adapted to communicate with each other. The invention provides a system comprising a local (200) unit and a remote (100) unit. The local unit comprises a local transmitter (270), a local receiver (280), a local sensor (290), and a local processor (210) connected to the local transmitter, the local receiver and the local sensor. The remote unit comprises a remote transmitter (170) adapted to transmit information to the local receiver (180), a remote receiver adapted for receiving information from the local transmitter, a remote sensor (190), and a remote processor (110) connected to the remote transmitter, the remote receiver and the remote sensor. The local sensor and the remote sensor are adapted to detect that the units have been arranged in a mating relationship with each other at a given point in time, this allowing the units to exchange information based upon that time.

摘要翻译： 本发明涉及适于彼此通信的电子控制装置的安全配对。 本发明提供一种包括本地（200）单元和远程（100）单元的系统。 本地单元包括本地发射机（270），本地接收机（280），本地传感器（290）和连接到本地发射机，本地接收机和本地传感器的本地处理器（210）。 远程单元包括适于向本地接收机（180）发送信息的远程发射机（170），适于从本地发射机接收信息的远程接收机，远程传感器（190）和连接到 遥控发射器，遥控接收器和遥控传感器。 本地传感器和远程传感器适于检测单元在给定时间点彼此配对关系，这允许单元基于该时间交换信息。

公开(公告)号：US07133329B2

公开(公告)日：2006-11-07

申请号：US10618878

申请日：2003-07-14

申请人： Ole Skyggebjerg ,  Lars Hofmann Christensen ,  Rasmus Panduro ,  Nina Bjorlig ,  Steffen Lav ,  Barry Weben ,  Manuel Alvarez-Icaza ,  Steven Syme

发明人： Ole Skyggebjerg ,  Lars Hofmann Christensen ,  Rasmus Panduro ,  Nina Bjorlig ,  Steffen Lav ,  Barry Weben ,  Manuel Alvarez-Icaza ,  Steven Syme

IPC分类号： G04F8/00 ,  G04F10/00

CPC分类号： A61M5/20 ,  A61J7/0436 ,  A61M5/178 ,  A61M5/28 ,  A61M5/3129 ,  A61M2005/3125 ,  A61M2205/50 ,  A61M2205/581 ,  G04B25/06 ,  G04F1/005

摘要： The invention relates to a timer device capable of performing one or more control actions in response to the time lapsed since a user initiated action took place. The timer device comprises contact means operatable between two conditions, timer means, and means for storing first and second time stamps. The device further comprises control means for setting a first time stamp in response to the contact means being operated between first and second conditions, setting a second time stamp in response to the contact means being operated between the second and first conditions, calculating the time elapsed between the two time stamps, comparing the elapsed time with a preset time value, and performing a control action if the elapsed time is greater than the preset time value.

摘要翻译： 本发明涉及一种定时器装置，其能够响应于由于用户发起动作而发生的时间而执行一个或多个控制动作。 定时器装置包括可在两个状态之间操作的接触装置，定时器装置和用于存储第一和第二时间戳的装置。 该装置还包括控制装置，用于响应于在第一和第二条件之间操作的接触装置来设置第一时间戳，响应于在第二和第一条件之间操作的接触装置设置第二时间戳，计算经过的时间 在两个时间戳之间，将经过的时间与预设时间值进行比较，以及如果经过时间大于预设时间值，则执行控制动作。