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公开(公告)号：US10466258B2
公开(公告)日：2019-11-05
申请号：US15477692
申请日：2017-04-03
Applicant: Omrix Biopharmaceuticals Ltd.
Inventor： Elena Grimberg , Roberto Meidler , Yonit Tiberman , Nadav Orr , Nadav Ashkenazy
Abstract: Provided is a method, device and system for an in-situ preparation of a sample, for example, for use in detecting the presence of, and/or quantifying, clottable fibrinogen in such a sample.
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公开(公告)号：US11009513B2
公开(公告)日：2021-05-18
申请号：US16566387
申请日：2019-09-10
Applicant: Omrix Biopharmaceuticals Ltd.
Inventor： Elena Grimberg , Roberto Meidler , Yonit Tiberman , Nadav Orr , Nadav Ashkenazy
Abstract: The present invention is directed to devices having a substance receiving portion; a membrane; and at least one blocking member configured for taking one position and another position to allow fluid communication when a vacuum force is applied to the bottom of the substance receiving portion for the purpose of an in-situ preparation of a sample to detect the presence of, and/or quantify, clottable fibrinogen. The present invention is also directed to corresponding methods, processes and systems.
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公开(公告)号：US10806755B2
公开(公告)日：2020-10-20
申请号：US14631099
申请日：2015-02-25
Applicant: Omrix Biopharmaceuticals Ltd.
Inventor： Roberto Meidler , Elena Grimberg , Oleg Belyaev , Yonit Tiberman , Israel Nur , Tamar Auerbach-Nevo
Abstract: Provided herein is a plasma-supplemented fibrinogen and/or fibrin formulation, method for the preparation and use thereof.
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Patent Agency Ranking
公开(公告)号：US12203947B2
公开(公告)日：2025-01-21
申请号：US17318707
申请日：2021-05-12
Applicant: Omrix Biopharmaceuticals Ltd.
Inventor： Elena Grimberg , Roberto Meidler , Yonit Tiberman , Nadav Orr , Nadav Ashkenazy
Abstract: The present invention is directed to devices having a substance receiving portion and a membrane constituting the bottom of the substance receiving portion and having such a structure as to allow fluid disposed in the substance receiving portion to be transferred therefrom through the membrane when a vacuum force is applied to the bottom of the substance receiving portion for the purpose of an in-situ preparation of a sample to detect the presence and/or quantify of clottable fibrinogen. The present invention is also directed to corresponding methods, processes and systems.
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公开(公告)号：US11918629B2
公开(公告)日：2024-03-05
申请号：US16710541
申请日：2019-12-11
Applicant: Omrix Biopharmaceuticals Ltd.
Inventor： Israel Nur , Elena Grimberg , Itai Podoler , Inbar Gahali-Sass , Erez Ilan , Ronen Eavri
IPC: A61K38/00 , A61K9/08 , A61K33/06 , A61K38/36 , A61K38/37 , A61K38/38 , A61K38/48 , A61P7/04 , A61P41/00
CPC classification number: A61K38/363 , A61K9/08 , A61K33/06 , A61K38/366 , A61K38/37 , A61K38/38 , A61K38/4833 , A61P7/04 , A61P41/00 , C12Y304/21005
Abstract: Provided herein are kits comprised of a first container including a solution of fibrinogen-containing component that includes fibrinogen at a concentration range of about 5 mg/ml to about 30 mg/ml, and having a total protein concentration range of about 15 mg/ml to about 40 mg/ml; and a second container that includes a solution of thrombin-containing component. Further provided are mixtures comprised of fibrinogen and thrombin, calcium ions, and albumin, the mixture being comprised of total protein in a range of about 2.5 mg/ml to about 30 mg/ml, fibrinogen in a range of about 50% to about 80% of total protein, and albumin in a range of more than 0.65 mg/ml to about 3 mg/ml. Further provided herein are methods for preventing or reducing tissue adhesion, and hydrogel materials made of fibrin.
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公开(公告)号：US20210263053A1
公开(公告)日：2021-08-26
申请号：US17318707
申请日：2021-05-12
Applicant: Omrix Biopharmaceuticals Ltd.
Inventor： Elena Grimberg , Roberto Meidler , Yonit Tiberman , Nadav Orr , Nadav Ashkenazy
Abstract: The present invention is directed to devices having a substance receiving portion; a membrane; and at least one blocking member configured for taking one position and another position to allow fluid communication when a vacuum force is applied to the bottom of the substance receiving portion for the purpose of an in-situ preparation of a sample to detect the presence of, and/or quantify, clottable fibrinogen. The present invention is also directed to corresponding methods, processes and systems.
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公开(公告)号：US20200033369A1
公开(公告)日：2020-01-30
申请号：US16566387
申请日：2019-09-10
Applicant: Omrix Biopharmaceuticals Ltd.
Inventor： Elena Grimberg , Roberto Meidler , Yonit Tiberman , Nadav Orr , Nadav Ashkenazy
Abstract: The present invention is directed to devices having a substance receiving portion; a membrane; and at least one blocking member configured for taking one position and another position to allow fluid communication when a vacuum force is applied to the bottom of the substance receiving portion for the purpose of an in-situ preparation of a sample to detect the presence of, and/or quantify, clottable fibrinogen. The present invention is also directed to corresponding methods, processes and systems.
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公开(公告)号：US20170285047A1
公开(公告)日：2017-10-05
申请号：US15477692
申请日：2017-04-03
Applicant: Omrix Biopharmaceuticals Ltd.
Inventor： Elena Grimberg , Roberto Meidler , Yonit Tiberman , Nadav Orr , Nadav Ashkenazy
CPC classification number: G01N33/86 , B01D61/18 , B01D2325/38 , B01L3/502 , B01L2300/0681 , B01L2300/0829 , C12Q1/56
Abstract: Provided is a method, device and system for an in-situ preparation of a sample, for example, for use in detecting the presence of, and/or quantifying, clottable fibrinogen in such a sample.
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