公开(公告)号：US20170190746A1

公开(公告)日：2017-07-06

申请号：US15394663

申请日：2016-12-29

Applicant: POSTECH ACADEMY-INDUSTRY FOUNDATION

Inventor： Hyung Joon CHA ,  Bong Hyuk CHOI ,  Eun Young JEON

IPC: C07K14/435 ,  A61L24/00 ,  A61L24/10 ,  C07K7/08 ,  A61K8/64

CPC classification number: C07K14/43504 ,  A61K8/64 ,  A61K8/987 ,  A61K38/00 ,  A61L24/0015 ,  A61L24/0031 ,  A61L24/043 ,  A61L24/108 ,  A61L26/0047 ,  A61L26/0052 ,  A61L26/0061 ,  A61L26/008 ,  A61L2300/412 ,  A61L2400/06 ,  A61Q19/00 ,  C07K7/08 ,  C07K2319/70 ,  C08L5/02 ,  C08L5/04 ,  C08L5/12 ,  C08L5/08 ,  C08L89/00

Abstract: Provided are a recombinant polypeptide in which a small leucine-rich proteoglycan mimetic sequence is attached to a terminal of a mussel adhesive protein, a composition for wound healing including the same, a bioadhesive material, and a preparation method thereof. According to the present disclosure, the recombinant polypeptide in which the small leucine-rich proteoglycan mimetic sequence is attached to the terminal of the mussel adhesive protein has an excellent epidermal regeneration effect in which the wound site is uniformly restored by promoting rapid wound healing at the wound site when being applied to the wound site and inducing formation of collagens which are arranged and concentrated at the wound site, and thus can be usefully used as various drugs, cosmetics, and quasi-drugs.